MCID: SLL002
MIFTS: 19

Sella Turcica Neoplasm

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Sella Turcica Neoplasm

MalaCards integrated aliases for Sella Turcica Neoplasm:

Name: Sella Turcica Neoplasm 12 15 70
Tumor of Sella Turcica 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3643
NCIt 50 C4944
UMLS 70 C0748616

Summaries for Sella Turcica Neoplasm

MalaCards based summary : Sella Turcica Neoplasm, also known as tumor of sella turcica, is related to pituitary adenoma and adenoma. An important gene associated with Sella Turcica Neoplasm is BRD1 (Bromodomain Containing 1), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and Prostaglandin Synthesis and Regulation. Affiliated tissues include pituitary, and related phenotypes are endocrine/exocrine gland and integument

Related Diseases for Sella Turcica Neoplasm

Diseases related to Sella Turcica Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 pituitary adenoma 29.6 PRL POMC GHRH
2 adenoma 29.6 PRL POMC GHRH
3 glomus tumor 10.1
4 adenohypophysitis 10.1 PRL POMC
5 acidophil adenoma 10.1 PRL POMC
6 chromophobe adenoma 10.1 PRL POMC
7 ectopic cushing syndrome 10.1 PRL POMC
8 abducens nerve disease 10.1 PRL POMC
9 tsh producing pituitary tumor 10.1 PRL POMC
10 hypothyroidism, congenital, nongoitrous, 4 10.1 PRL POMC
11 benign essential hypertension 10.1 PRL POMC
12 nelson syndrome 10.1 PRL POMC
13 cranial nerve palsy 10.1 PRL POMC
14 pituitary apoplexy 10.1 PRL POMC
15 empty sella syndrome 10.1 PRL POMC
16 van maldergem syndrome 1 10.1 PRL POMC
17 acth deficiency, isolated 10.1 PRL POMC
18 melancholia 10.1 PRL POMC
19 steroid inherited metabolic disorder 10.1 PRL POMC
20 pituitary tumors 10.1 PRL POMC
21 diabetes insipidus, neurohypophyseal 10.0 PRL POMC
22 diabetes insipidus 10.0 PRL POMC
23 sebaceous gland disease 10.0 PRL POMC
24 endogenous depression 10.0 PRL POMC
25 sexual disorder 10.0 PRL POMC
26 acth-secreting pituitary adenoma 10.0 PRL POMC
27 acth-independent macronodular adrenal hyperplasia 10.0 POMC EDNRA
28 postpartum depression 10.0 PRL POMC
29 central nervous system benign neoplasm 10.0 PRL POMC
30 persistent fetal circulation syndrome 10.0 POMC EDNRA
31 adrenal gland disease 10.0 PRL POMC
32 gynecomastia 10.0 PRL POMC
33 disorder of sexual development 10.0 PRL POMC
34 femoral cancer 10.0 TCF21 EDNRA
35 migraine without aura 10.0 PRL EDNRA
36 amenorrhea 10.0 PRL POMC
37 hyperandrogenism 10.0 PRL POMC
38 pain agnosia 10.0 TCF21 POMC
39 agnosia 10.0 TCF21 POMC
40 thyroid gland disease 10.0 PRL POMC
41 intracranial berry aneurysm 9.9 POMC EDNRA
42 sleep disorder 9.9 PRL POMC
43 pituitary adenoma, prolactin-secreting 9.9 PRL POMC
44 substance abuse 9.9 PRL POMC
45 lactocele 9.9 PRL GHRH
46 gigantism 9.9 PRL GHRH
47 pseudohypoparathyroidism, type ia 9.9 PRL GHRH
48 hyperthyroidism 9.8 PRL POMC
49 fibrous dysplasia 9.8 PRL GHRH
50 impotence 9.8 PRL POMC EDNRA

Graphical network of the top 20 diseases related to Sella Turcica Neoplasm:



Diseases related to Sella Turcica Neoplasm

Symptoms & Phenotypes for Sella Turcica Neoplasm

MGI Mouse Phenotypes related to Sella Turcica Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.55 EDNRA GHRH POMC PRL TCF21
2 integument MP:0010771 9.35 BRD1 EDNRA POMC PRL TCF21
3 liver/biliary system MP:0005370 8.92 BRD1 GHRH POMC PRL

Drugs & Therapeutics for Sella Turcica Neoplasm

Search Clinical Trials , NIH Clinical Center for Sella Turcica Neoplasm

Genetic Tests for Sella Turcica Neoplasm

Anatomical Context for Sella Turcica Neoplasm

MalaCards organs/tissues related to Sella Turcica Neoplasm:

40
Pituitary

Publications for Sella Turcica Neoplasm

Articles related to Sella Turcica Neoplasm:

# Title Authors PMID Year
1
Glomus Tumor of Sella Turcica With Synaptophysin Expression Mimicking Pituitary Adenoma. 61
31948309 2020

Variations for Sella Turcica Neoplasm

Expression for Sella Turcica Neoplasm

Search GEO for disease gene expression data for Sella Turcica Neoplasm.

Pathways for Sella Turcica Neoplasm

Pathways related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.07 PRL POMC
2 10.43 PRL EDNRA
3 9.92 PRL POMC

GO Terms for Sella Turcica Neoplasm

Biological processes related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 8.62 POMC EDNRA

Molecular functions related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 PRL POMC GHRH

Sources for Sella Turcica Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....