MCID: SLL002
MIFTS: 20

Sella Turcica Neoplasm

Categories: Bone diseases, Cancer diseases
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Aliases & Classifications for Sella Turcica Neoplasm

MalaCards integrated aliases for Sella Turcica Neoplasm:

Name: Sella Turcica Neoplasm 11 14 71
Tumor of Sella Turcica 11

Classifications:



External Ids:

Disease Ontology 11 DOID:3643
NCIt 49 C4944
UMLS 71 C0748616

Summaries for Sella Turcica Neoplasm

MalaCards based summary: Sella Turcica Neoplasm, also known as tumor of sella turcica, is related to pituitary adenoma and adenoma. An important gene associated with Sella Turcica Neoplasm is POMC (Proopiomelanocortin), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and Splicing factor NOVA regulated synaptic proteins. Affiliated tissues include bone and pituitary, and related phenotype is liver/biliary system.

Related Diseases for Sella Turcica Neoplasm

Diseases related to Sella Turcica Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 pituitary adenoma 29.8 PRL POMC GHRH
2 adenoma 29.8 PRL POMC GHRH
3 suprasellar meningioma 10.2 POMC NF2
4 chiasmal syndrome 10.1 PRL POMC
5 cranial nerve malignant neoplasm 10.1 POMC NF2
6 prolactin producing pituitary tumor 10.1 PRL POMC
7 sphenoorbital meningioma 10.1 TRAF7 NF2
8 foramen magnum meningioma 10.1 TRAF7 NF2
9 acidophil adenoma 10.1 PRL POMC
10 chromophobe adenoma 10.1 PRL POMC
11 ectopic cushing syndrome 10.1 PRL POMC
12 childhood meningioma 10.1 TRAF7 NF2
13 cavernous sinus meningioma 10.1 TRAF7 NF2
14 cerebral falx meningioma 10.1 TRAF7 NF2
15 psammomatous meningioma 10.1 TRAF7 NF2
16 parasagittal meningioma 10.1 TRAF7 NF2
17 tsh producing pituitary tumor 10.1 PRL POMC
18 microcystic meningioma 10.1 TRAF7 NF2
19 intraventricular meningioma 10.1 TRAF7 NF2
20 cerebral convexity meningioma 10.1 TRAF7 NF2
21 abducens palsy 10.1 PRL POMC
22 optic nerve sheath meningioma 10.1 TRAF7 NF2
23 olfactory groove meningioma 10.1 TRAF7 NF2
24 sheehan syndrome 10.1 PRL POMC
25 angiomatous meningioma 10.1 TRAF7 NF2
26 intraneural perineurioma 10.1 TRAF7 NF2
27 paragangliomas 1 10.1
28 glomus tumor 10.1
29 chordoid meningioma 10.1 TRAF7 NF2
30 petroclival meningioma 10.1 TRAF7 NF2
31 brain meningioma 10.1 TRAF7 NF2
32 secretory meningioma 10.1 TRAF7 NF2
33 melancholia 10.1 PRL POMC
34 rhabdoid meningioma 10.1 TRAF7 NF2
35 partial third-nerve palsy 10.1 PRL POMC
36 nelson syndrome 10.1 PRL POMC
37 skull base meningioma 10.1 TRAF7 NF2
38 sexual sadism 10.1 PRL POMC
39 meningothelial meningioma 10.1 TRAF7 NF2
40 cerebral meningioma 10.1 TRAF7 NF2
41 hypothyroidism, congenital, nongoitrous, 4 10.1 PRL POMC
42 clear cell meningioma 10.1 TRAF7 NF2
43 skull base cancer 10.1 TRAF7 NF2
44 fibrous meningioma 10.1 TRAF7 NF2
45 acth deficiency, isolated 10.1 PRL POMC
46 inappropriate adh syndrome 10.1 PRL POMC
47 pituitary apoplexy 10.1 PRL POMC
48 polyp of corpus uteri 10.1 PRL NF2
49 intracranial meningioma 10.1 TRAF7 NF2
50 van maldergem syndrome 1 10.1 PRL POMC

Graphical network of the top 20 diseases related to Sella Turcica Neoplasm:



Diseases related to Sella Turcica Neoplasm

Symptoms & Phenotypes for Sella Turcica Neoplasm

MGI Mouse Phenotypes related to Sella Turcica Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 liver/biliary system MP:0005370 9.02 EPB41 GHRH NF2 POMC PRL

Drugs & Therapeutics for Sella Turcica Neoplasm

Search Clinical Trials, NIH Clinical Center for Sella Turcica Neoplasm

Genetic Tests for Sella Turcica Neoplasm

Anatomical Context for Sella Turcica Neoplasm

Organs/tissues related to Sella Turcica Neoplasm:

MalaCards : Bone, Pituitary

Publications for Sella Turcica Neoplasm

Articles related to Sella Turcica Neoplasm:

# Title Authors PMID Year
1
Glomus Tumor of Sella Turcica With Synaptophysin Expression Mimicking Pituitary Adenoma. 62
31948309 2020

Variations for Sella Turcica Neoplasm

Expression for Sella Turcica Neoplasm

Search GEO for disease gene expression data for Sella Turcica Neoplasm.

Pathways for Sella Turcica Neoplasm

Pathways related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.93 POMC GHRH
2 10.55 EPB41L2 EPB41
3 9.92 PRL POMC

GO Terms for Sella Turcica Neoplasm

Biological processes related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actomyosin structure organization GO:0031032 9.46 EPB41L2 EPB41
2 cortical actin cytoskeleton organization GO:0030866 9.26 EPB41L2 EPB41
3 positive regulation of protein localization to cell cortex GO:1904778 8.92 EPB41L2 EPB41

Molecular functions related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 spectrin binding GO:0030507 9.46 EPB41L2 EPB41
2 hormone activity GO:0005179 9.35 PRL POMC GHRH
3 cytoskeletal protein binding GO:0008092 8.8 NF2 EPB41L2 EPB41

Sources for Sella Turcica Neoplasm

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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