Sella Turcica Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Sella Turcica Neoplasm

MalaCards integrated aliases for Sella Turcica Neoplasm:

Name: Sella Turcica Neoplasm ¹² ¹⁵ ⁷⁰

Tumor of Sella Turcica ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Bone diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3643

NCIt ⁵⁰ C4944

UMLS ⁷⁰ C0748616

Sources

Summaries for Sella Turcica Neoplasm

MalaCards based summary : Sella Turcica Neoplasm, also known as tumor of sella turcica, is related to pituitary adenoma and adenoma. An important gene associated with Sella Turcica Neoplasm is BRD1 (Bromodomain Containing 1), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and Prostaglandin Synthesis and Regulation. Affiliated tissues include pituitary, and related phenotypes are endocrine/exocrine gland and integument

Sources

Related Diseases for Sella Turcica Neoplasm

Diseases related to Sella Turcica Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)

#	Related Disease	Score	Top Affiliating Genes
1	pituitary adenoma	29.6	PRL POMC GHRH
2	adenoma	29.6	PRL POMC GHRH
3	glomus tumor	10.1
4	adenohypophysitis	10.1	PRL POMC
5	acidophil adenoma	10.1	PRL POMC
6	chromophobe adenoma	10.1	PRL POMC
7	ectopic cushing syndrome	10.1	PRL POMC
8	abducens nerve disease	10.1	PRL POMC
9	tsh producing pituitary tumor	10.1	PRL POMC
10	hypothyroidism, congenital, nongoitrous, 4	10.1	PRL POMC
11	benign essential hypertension	10.1	PRL POMC
12	nelson syndrome	10.1	PRL POMC
13	cranial nerve palsy	10.1	PRL POMC
14	pituitary apoplexy	10.1	PRL POMC
15	empty sella syndrome	10.1	PRL POMC
16	van maldergem syndrome 1	10.1	PRL POMC
17	acth deficiency, isolated	10.1	PRL POMC
18	melancholia	10.1	PRL POMC
19	steroid inherited metabolic disorder	10.1	PRL POMC
20	pituitary tumors	10.1	PRL POMC
21	diabetes insipidus, neurohypophyseal	10.0	PRL POMC
22	diabetes insipidus	10.0	PRL POMC
23	sebaceous gland disease	10.0	PRL POMC
24	endogenous depression	10.0	PRL POMC
25	sexual disorder	10.0	PRL POMC
26	acth-secreting pituitary adenoma	10.0	PRL POMC
27	acth-independent macronodular adrenal hyperplasia	10.0	POMC EDNRA
28	postpartum depression	10.0	PRL POMC
29	central nervous system benign neoplasm	10.0	PRL POMC
30	persistent fetal circulation syndrome	10.0	POMC EDNRA
31	adrenal gland disease	10.0	PRL POMC
32	gynecomastia	10.0	PRL POMC
33	disorder of sexual development	10.0	PRL POMC
34	femoral cancer	10.0	TCF21 EDNRA
35	migraine without aura	10.0	PRL EDNRA
36	amenorrhea	10.0	PRL POMC
37	hyperandrogenism	10.0	PRL POMC
38	pain agnosia	10.0	TCF21 POMC
39	agnosia	10.0	TCF21 POMC
40	thyroid gland disease	10.0	PRL POMC
41	intracranial berry aneurysm	9.9	POMC EDNRA
42	sleep disorder	9.9	PRL POMC
43	pituitary adenoma, prolactin-secreting	9.9	PRL POMC
44	substance abuse	9.9	PRL POMC
45	lactocele	9.9	PRL GHRH
46	gigantism	9.9	PRL GHRH
47	pseudohypoparathyroidism, type ia	9.9	PRL GHRH
48	hyperthyroidism	9.8	PRL POMC
49	fibrous dysplasia	9.8	PRL GHRH
50	impotence	9.8	PRL POMC EDNRA

Graphical network of the top 20 diseases related to Sella Turcica Neoplasm:

Sources

Symptoms & Phenotypes for Sella Turcica Neoplasm

MGI Mouse Phenotypes related to Sella Turcica Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.55	EDNRA GHRH POMC PRL TCF21
2	integument	MP:0010771	9.35	BRD1 EDNRA POMC PRL TCF21
3	liver/biliary system	MP:0005370	8.92	BRD1 GHRH POMC PRL

Sources

Drugs & Therapeutics for Sella Turcica Neoplasm

Search Clinical Trials , NIH Clinical Center for Sella Turcica Neoplasm

Sources

Genetic Tests for Sella Turcica Neoplasm

Sources

Anatomical Context for Sella Turcica Neoplasm

MalaCards organs/tissues related to Sella Turcica Neoplasm:

⁴⁰

Pituitary

Sources

Publications for Sella Turcica Neoplasm

Articles related to Sella Turcica Neoplasm:

#	Title	Authors	PMID	Year
1	Glomus Tumor of Sella Turcica With Synaptophysin Expression Mimicking Pituitary Adenoma. ⁶¹	Tsang JCH...Cheuk W	31948309	2020

Sources

Genes for Sella Turcica Neoplasm

Genes related to Sella Turcica Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	BRD1	Bromodomain Containing 1	Protein Coding	5.74	DISEASES inferred ¹⁵
2	POMC	Proopiomelanocortin	Protein Coding	5.29	DISEASES inferred ¹⁵
3	PRL	Prolactin	Protein Coding	5.22	DISEASES inferred ¹⁵
4	TCF21	Transcription Factor 21	Protein Coding	4.96	DISEASES inferred ¹⁵
5	GHRH	Growth Hormone Releasing Hormone	Protein Coding	4.83	DISEASES inferred ¹⁵
6	EDNRA	Endothelin Receptor Type A	Protein Coding	4.72	DISEASES inferred ¹⁵

Sources

Variations for Sella Turcica Neoplasm

Sources

Expression for Sella Turcica Neoplasm

Search GEO for disease gene expression data for Sella Turcica Neoplasm.

Sources

Pathways for Sella Turcica Neoplasm

Pathways related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Glucocorticoid receptor regulatory network ¹	11.07	PRL POMC
2	Prostaglandin Synthesis and Regulation ¹	10.43	PRL EDNRA
3	Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics ⁶⁰	9.92	PRL POMC

Sources

GO Terms for Sella Turcica Neoplasm

Biological processes related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	regulation of blood pressure	GO:0008217	8.62	POMC EDNRA

Molecular functions related to Sella Turcica Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hormone activity	GO:0005179	8.8	PRL POMC GHRH

Sources

Sources for Sella Turcica Neoplasm

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia