MCID: SMN006
MIFTS: 23

Seminal Vesicle Tumor

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Seminal Vesicle Tumor

MalaCards integrated aliases for Seminal Vesicle Tumor:

Name: Seminal Vesicle Tumor 12 15
Tumor of Seminal Vesicle 12 73
Seminal Vesicle Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3855
NCIt 50 C39908
SNOMED-CT 68 236740006
UMLS 73 C0341767

Summaries for Seminal Vesicle Tumor

MalaCards based summary : Seminal Vesicle Tumor, also known as tumor of seminal vesicle, is related to renal cell carcinoma, nonpapillary and neural crest tumor. An important gene associated with Seminal Vesicle Tumor is DIRC2 (Disrupted In Renal Carcinoma 2). Related phenotype is Decreased viability in esophageal squamous lineage.

Related Diseases for Seminal Vesicle Tumor

Diseases related to Seminal Vesicle Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)
# Related Disease Score Top Affiliating Genes
1 renal cell carcinoma, nonpapillary 29.2 DIRC2 KRT7 SDHB
2 neural crest tumor 10.8 SDHA SDHB
3 persistent generalized lymphadenopathy 10.7 SDHA SDHB
4 carney triad 10.7 SDHA SDHB
5 lymph node disease 10.5 SDHA SDHB
6 testicular malignant germ cell cancer 10.5 AFP GPC3
7 ovarian embryonal carcinoma 10.5 AFP GPC3
8 hepatic adenomas, familial 10.4 AFP GPC3
9 hereditary paraganglioma-pheochromocytoma syndromes 10.4 SDHA SDHB
10 proliferating trichilemmal cyst 10.4 KRT18 KRT7
11 epithelioid trophoblastic tumor 10.4 KRT18 KRT7
12 cutaneous adenocystic carcinoma 10.4 KRT18 KRT7
13 metanephric adenoma 10.3 KRT18 KRT7
14 mitochondrial complex ii deficiency 10.3 SDHA SDHB
15 renal oncocytoma 10.3 KRT7 SDHB
16 pleomorphic carcinoma 10.3 KRT18 KRT7
17 intrahepatic bile duct adenoma 10.3 AFP KRT7
18 mucinous tubular and spindle renal cell carcinoma 10.3 KRT18 KRT7
19 renal pelvis adenocarcinoma 10.3 AFP KRT7
20 ovarian germ cell cancer 10.3 AFP KRT7
21 lymphoepithelioma-like carcinoma 10.3 KRT18 KRT7
22 benign mesothelioma 10.3 GPC3 KRT7
23 bile duct cystadenocarcinoma 10.3 AFP KRT7
24 intratubular embryonal carcinoma 10.3 AFP KRT7
25 choriocarcinoma of the testis 10.3 AFP KRT7
26 adenomatoid tumor 10.3 AFP KRT7
27 ovarian clear cell carcinoma 10.2 GPC3 KRT7
28 sertoli-leydig cell tumor 10.2 AFP KRT7
29 malignant biphasic mesothelioma 10.2 AFP KRT7
30 mammary paget's disease 10.2 KRT18 KRT7
31 intraneural perineurioma 10.2 KRT18 KRT7
32 tuberculous epididymitis 10.2 AFP KLK3
33 nephrogenic adenofibroma 10.2 KRT18 KRT7
34 cystadenofibroma 10.2 AFP KRT7
35 nephrogenic adenoma 10.2 KLK3 KRT7
36 rete testis adenocarcinoma 10.2 AFP KLK3
37 male reproductive organ benign neoplasm 10.1 DIRC2 KLK3 STK10
38 testicular germ cell tumor 10.1 AFP GPC3 STK10
39 bladder neck obstruction 10.1 AFP KLK3
40 rete testis neoplasm 10.1 AFP KLK3
41 ovarian brenner tumor 10.1 KRT18 KRT7
42 prostate squamous cell carcinoma 10.1 KLK3 KRT7
43 acinar cell carcinoma 10.1 AFP KRT7
44 germ cell and embryonal cancer 10.1 AFP KRT7
45 urethral diverticulum 10.1 KLK3 KRT7
46 glomus tumor 10.1 SDHB SYP
47 pineal gland cancer 10.0 KRT18 SYP
48 ovary neuroendocrine neoplasm 10.0 KRT7 SYP
49 malignant sertoli cell tumor 10.0 AFP SYP
50 testicular yolk sac tumor 10.0 AFP GPC3

Graphical network of the top 20 diseases related to Seminal Vesicle Tumor:



Diseases related to Seminal Vesicle Tumor

Symptoms & Phenotypes for Seminal Vesicle Tumor

GenomeRNAi Phenotypes related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability in esophageal squamous lineage GR00235-A 9.17 AFP DIRC2 EDA KLK3 KRT7 SDHA

Drugs & Therapeutics for Seminal Vesicle Tumor

Search Clinical Trials , NIH Clinical Center for Seminal Vesicle Tumor

Genetic Tests for Seminal Vesicle Tumor

Anatomical Context for Seminal Vesicle Tumor

Publications for Seminal Vesicle Tumor

Articles related to Seminal Vesicle Tumor:

# Title Authors Year
1
Peripheral primitive neuroectodermal tumor of seminal vesicles: is there a role for relatively aggressive treatment modalities? ( 25641454 )
2014
2
Recurrent mullerian adenosarcoma like tumor of seminal vesicle. ( 20551553 )
2010
3
Epithelial-stromal tumor of seminal vesicle in a patient with chromophobe renal cell carcinoma and small lymphocytic lymphoma. ( 18995209 )
2008

Variations for Seminal Vesicle Tumor

Expression for Seminal Vesicle Tumor

Search GEO for disease gene expression data for Seminal Vesicle Tumor.

Pathways for Seminal Vesicle Tumor

GO Terms for Seminal Vesicle Tumor

Cellular components related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.62 SDHA SDHB

Biological processes related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.43 AFP GPC3 KLK3
2 tricarboxylic acid cycle GO:0006099 9.16 SDHA SDHB
3 respiratory electron transport chain GO:0022904 8.96 SDHA SDHB
4 succinate metabolic process GO:0006105 8.62 SDHA SDHB

Molecular functions related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 succinate dehydrogenase (ubiquinone) activity GO:0008177 8.62 SDHA SDHB

Sources for Seminal Vesicle Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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