Seminal Vesicle Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Seminal Vesicle Tumor

MalaCards integrated aliases for Seminal Vesicle Tumor:

Name: Seminal Vesicle Tumor ¹² ¹⁵

Tumor of Seminal Vesicle ¹² ⁷³

Seminal Vesicle Neoplasm ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3855

NCIt ⁵⁰ C39908

SNOMED-CT ⁶⁸ 236740006

UMLS ⁷³ C0341767

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Summaries for Seminal Vesicle Tumor

MalaCards based summary : Seminal Vesicle Tumor, also known as tumor of seminal vesicle, is related to renal cell carcinoma, nonpapillary and neural crest tumor. An important gene associated with Seminal Vesicle Tumor is DIRC2 (Disrupted In Renal Carcinoma 2). Related phenotype is Decreased viability in esophageal squamous lineage.

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Related Diseases for Seminal Vesicle Tumor

Diseases related to Seminal Vesicle Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 112)

#	Related Disease	Score	Top Affiliating Genes
1	renal cell carcinoma, nonpapillary	29.2	DIRC2 KRT7 SDHB
2	neural crest tumor	10.8	SDHA SDHB
3	persistent generalized lymphadenopathy	10.7	SDHA SDHB
4	carney triad	10.7	SDHA SDHB
5	lymph node disease	10.5	SDHA SDHB
6	testicular malignant germ cell cancer	10.5	AFP GPC3
7	ovarian embryonal carcinoma	10.5	AFP GPC3
8	hepatic adenomas, familial	10.4	AFP GPC3
9	hereditary paraganglioma-pheochromocytoma syndromes	10.4	SDHA SDHB
10	proliferating trichilemmal cyst	10.4	KRT18 KRT7
11	epithelioid trophoblastic tumor	10.4	KRT18 KRT7
12	cutaneous adenocystic carcinoma	10.4	KRT18 KRT7
13	metanephric adenoma	10.3	KRT18 KRT7
14	mitochondrial complex ii deficiency	10.3	SDHA SDHB
15	renal oncocytoma	10.3	KRT7 SDHB
16	pleomorphic carcinoma	10.3	KRT18 KRT7
17	intrahepatic bile duct adenoma	10.3	AFP KRT7
18	mucinous tubular and spindle renal cell carcinoma	10.3	KRT18 KRT7
19	renal pelvis adenocarcinoma	10.3	AFP KRT7
20	ovarian germ cell cancer	10.3	AFP KRT7
21	lymphoepithelioma-like carcinoma	10.3	KRT18 KRT7
22	benign mesothelioma	10.3	GPC3 KRT7
23	bile duct cystadenocarcinoma	10.3	AFP KRT7
24	intratubular embryonal carcinoma	10.3	AFP KRT7
25	choriocarcinoma of the testis	10.3	AFP KRT7
26	adenomatoid tumor	10.3	AFP KRT7
27	ovarian clear cell carcinoma	10.2	GPC3 KRT7
28	sertoli-leydig cell tumor	10.2	AFP KRT7
29	malignant biphasic mesothelioma	10.2	AFP KRT7
30	mammary paget's disease	10.2	KRT18 KRT7
31	intraneural perineurioma	10.2	KRT18 KRT7
32	tuberculous epididymitis	10.2	AFP KLK3
33	nephrogenic adenofibroma	10.2	KRT18 KRT7
34	cystadenofibroma	10.2	AFP KRT7
35	nephrogenic adenoma	10.2	KLK3 KRT7
36	rete testis adenocarcinoma	10.2	AFP KLK3
37	male reproductive organ benign neoplasm	10.1	DIRC2 KLK3 STK10
38	testicular germ cell tumor	10.1	AFP GPC3 STK10
39	bladder neck obstruction	10.1	AFP KLK3
40	rete testis neoplasm	10.1	AFP KLK3
41	ovarian brenner tumor	10.1	KRT18 KRT7
42	prostate squamous cell carcinoma	10.1	KLK3 KRT7
43	acinar cell carcinoma	10.1	AFP KRT7
44	germ cell and embryonal cancer	10.1	AFP KRT7
45	urethral diverticulum	10.1	KLK3 KRT7
46	glomus tumor	10.1	SDHB SYP
47	pineal gland cancer	10.0	KRT18 SYP
48	ovary neuroendocrine neoplasm	10.0	KRT7 SYP
49	malignant sertoli cell tumor	10.0	AFP SYP
50	testicular yolk sac tumor	10.0	AFP GPC3

Graphical network of the top 20 diseases related to Seminal Vesicle Tumor:

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Symptoms & Phenotypes for Seminal Vesicle Tumor

GenomeRNAi Phenotypes related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased viability in esophageal squamous lineage	GR00235-A	9.17	AFP DIRC2 EDA KLK3 KRT7 SDHA

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Drugs & Therapeutics for Seminal Vesicle Tumor

Search Clinical Trials , NIH Clinical Center for Seminal Vesicle Tumor

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Genetic Tests for Seminal Vesicle Tumor

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Anatomical Context for Seminal Vesicle Tumor

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Publications for Seminal Vesicle Tumor

Articles related to Seminal Vesicle Tumor:

#	Title	Authors	Year
1	Peripheral primitive neuroectodermal tumor of seminal vesicles: is there a role for relatively aggressive treatment modalities? ( 25641454 )	Crestani A....Zattoni F.	2014
2	Recurrent mullerian adenosarcoma like tumor of seminal vesicle. ( 20551553 )	Chheda N....Tongaonkar H.	2010
3	Epithelial-stromal tumor of seminal vesicle in a patient with chromophobe renal cell carcinoma and small lymphocytic lymphoma. ( 18995209 )	Thway K....Fisher C.	2008

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Genes for Seminal Vesicle Tumor

Genes related to Seminal Vesicle Tumor (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DIRC2	Disrupted In Renal Carcinoma 2	Protein Coding	16.11	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	STK10	Serine/Threonine Kinase 10	Protein Coding	16	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	SDHA	Succinate Dehydrogenase Complex Flavoprotein Subunit A	Protein Coding	15.34	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	SDHB	Succinate Dehydrogenase Complex Iron Sulfur Subunit B	Protein Coding	14.75	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	GPC3	Glypican 3	Protein Coding	14.7	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	EDA	Ectodysplasin A	Protein Coding	14.57	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	KRT18	Keratin 18	Protein Coding	14.5	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	KRT7	Keratin 7	Protein Coding	13.95	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	KLK3	Kallikrein Related Peptidase 3	Protein Coding	13.89	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	SYP	Synaptophysin	Protein Coding	13.84	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	AFP	Alpha Fetoprotein	Protein Coding	13.34	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Seminal Vesicle Tumor

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Expression for Seminal Vesicle Tumor

Search GEO for disease gene expression data for Seminal Vesicle Tumor.

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Pathways for Seminal Vesicle Tumor

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GO Terms for Seminal Vesicle Tumor

Cellular components related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	GO:0005749	8.62	SDHA SDHB

Biological processes related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular protein metabolic process	GO:0044267	9.43	AFP GPC3 KLK3
2	tricarboxylic acid cycle	GO:0006099	9.16	SDHA SDHB
3	respiratory electron transport chain	GO:0022904	8.96	SDHA SDHB
4	succinate metabolic process	GO:0006105	8.62	SDHA SDHB

Molecular functions related to Seminal Vesicle Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	succinate dehydrogenase (ubiquinone) activity	GO:0008177	8.62	SDHA SDHB

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Sources for Seminal Vesicle Tumor

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