MCID: SMN007
MIFTS: 46

Seminoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Seminoma

MalaCards integrated aliases for Seminoma:

Name: Seminoma 12 77 56 45 15 74
Seminoma, Pure 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4440
MeSH 45 D018239
NCIt 51 C7328 C9309
SNOMED-CT 69 36741007
UMLS 74 C0036631

Summaries for Seminoma

Disease Ontology : 12 A germinoma that has material basis in cells that make sperm and eggs.

MalaCards based summary : Seminoma, also known as seminoma, pure, is related to testicular seminoma and spermatocytoma. An important gene associated with Seminoma is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Granisetron and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include testis, bone and lymph node, and related phenotype is reproductive system.

Wikipedia : 77 A Seminoma is a germ cell tumor of the testicle or, more rarely, the mediastinum or other extra-gonadal... more...

Related Diseases for Seminoma

Diseases related to Seminoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 273)
# Related Disease Score Top Affiliating Genes
1 testicular seminoma 34.2 AFP CGA CGB3 TSPY1
2 spermatocytoma 33.4 KIT MAGEA4
3 testicular germ cell tumor 33.2 AFP ALPG ALPP CGB3 FGFR3 KIT
4 extragonadal seminoma 33.1 AFP KIT POU5F1 TNFRSF8
5 nonseminomatous germ cell tumor 32.6 AFP CGB7
6 embryonal carcinoma 32.1 AFP KIT POU5F1 TNFRSF8
7 gonadoblastoma 30.7 ALPP KIT TSPY1
8 brain germinoma 30.2 AFP POU5F1
9 testicular cancer 30.2 AFP ALPP CGA CGB3 MAGEA4 TSPY1
10 extragonadal germ cell cancer 30.2 AFP POU5F1
11 dysgerminoma 30.1 AFP ALPP ENO2 KIT TSPY1
12 teratoma 30.0 AFP CGA CGB3 ENO2 KIT POU5F1
13 mixed germ cell tumor 30.0 AFP CGA CGB3 KIT
14 mature teratoma 30.0 AFP POU5F1
15 malignant teratoma 29.9 AFP ENO2 POU5F1
16 malignant sertoli cell tumor 29.8 AFP ENO2
17 germ cell cancer 29.8 AFP ALPG ALPP CGA ESR2 KIT
18 choriocarcinoma 29.8 ALPG ALPP CGA CGB3 CGB7
19 intratubular embryonal carcinoma 29.2 AFP KIT POU5F1 TNFRSF8
20 testis seminoma 12.3
21 testicular spermatocytic seminoma 12.3
22 mediastinum seminoma 12.2
23 tubular variant testicular seminoma 12.1
24 cribriform variant testicular seminoma 12.1
25 pseudoglandular variant testicular seminoma 12.1
26 mixed germ cell cancer 11.1
27 cryptorchidism, unilateral or bilateral 10.4
28 ovarian mixed germ cell neoplasm 10.4 AFP CGA
29 hepatic angiomyolipoma 10.4 AFP KIT
30 polyembryoma 10.4 AFP CGA
31 tuberculous epididymitis 10.3 AFP CGB3
32 testicular malignant germ cell cancer 10.3 AFP ALPP
33 central nervous system germinoma 10.3 ALPP POU5F1
34 luteoma 10.3 CGA FGFR3
35 sarcomatoid renal cell carcinoma 10.3 CGB3 KIT
36 persistent mullerian duct syndrome 10.3
37 germ cells tumors 10.3
38 central nervous system germ cell tumor 10.3 AFP POU5F1
39 mediastinal cancer 10.3 AFP KIT
40 embryonal testis carcinoma 10.3 AFP POU5F1
41 mixed type thymoma 10.3 KIT PDPN
42 germinoma 10.3
43 mixed germ cell-sex cord neoplasm 10.3 KIT POU5F1 TSPY1
44 pediatric ovarian germ cell tumor 10.2 ALPP ENO2
45 chromosomal triplication 10.2 AFP CGA CGB3
46 pediatric ovarian dysgerminoma 10.2 ALPP ENO2
47 aggressive digital papillary adenocarcinoma 10.2 KIT PDPN
48 lymphoma 10.2
49 sarcoma 10.2
50 in situ carcinoma 10.2

Graphical network of the top 20 diseases related to Seminoma:



Diseases related to Seminoma

Symptoms & Phenotypes for Seminoma

MGI Mouse Phenotypes related to Seminoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 reproductive system MP:0005389 9.23 AFP ALPG CGA ESR2 FGFR3 KIT

Drugs & Therapeutics for Seminoma

Drugs for Seminoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 141)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Granisetron Approved, Investigational Phase 3 109889-09-0 3510
2
Bleomycin Approved, Investigational Phase 2, Phase 3,Phase 3 11056-06-7 5360373
3
Etoposide Approved Phase 2, Phase 3,Phase 3 33419-42-0 36462
4
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
5
Paclitaxel Approved, Vet_approved Phase 2, Phase 3,Phase 3,Phase 1 33069-62-4 36314
6
Cisplatin Approved Phase 2, Phase 3,Phase 3,Phase 1 15663-27-1 2767 441203 84093
7
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
8
Mechlorethamine Approved, Investigational Phase 3,Phase 1,Phase 2 51-75-2 4033
9
Ifosfamide Approved Phase 3,Phase 1,Phase 2 3778-73-2 3690
10
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 50-02-2 5743
11
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 1,Phase 2 1177-87-3
12
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
13
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
14
Captopril Approved Phase 3 62571-86-2 44093
15
Ribavirin Approved Phase 3 36791-04-5 37542
16
Palivizumab Approved, Investigational Phase 3 188039-54-5
17
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
18
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
19
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
20
Caspofungin Approved Phase 3 162808-62-0, 179463-17-3 2826718 468682
21
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
22
Ondansetron Approved Phase 3 99614-02-5 4595
23
Promethazine Approved, Investigational Phase 3 60-87-7 4927
24
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
25
Vinblastine Approved Phase 3 865-21-4 241903 13342
26 Serotonin Antagonists Phase 3
27 Antiemetics Phase 3,Phase 2
28 Serotonin Agents Phase 3
29 Neurotransmitter Agents Phase 3
30 Gastrointestinal Agents Phase 3,Phase 2
31 Autonomic Agents Phase 3,Phase 2
32 Peripheral Nervous System Agents Phase 3,Phase 2
33 Antibiotics, Antitubercular Phase 2, Phase 3,Phase 3
34 Antimitotic Agents Phase 2, Phase 3,Phase 3,Phase 1
35 Topoisomerase Inhibitors Phase 2, Phase 3,Phase 3
36 Etoposide phosphate Phase 2, Phase 3,Phase 3
37 Anti-Bacterial Agents Phase 2, Phase 3,Phase 3
38 Albumin-Bound Paclitaxel Phase 2, Phase 3,Phase 3,Phase 1
39 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3,Phase 1
40 Immunologic Factors Phase 3,Phase 1,Phase 2
41 Antineoplastic Agents, Alkylating Phase 3,Phase 1,Phase 2
42 Alkylating Agents Phase 3,Phase 1,Phase 2
43 Immunosuppressive Agents Phase 3,Phase 1,Phase 2
44 Antiviral Agents Phase 3,Phase 1,Phase 2
45 Anti-Infective Agents Phase 3,Phase 1,Phase 2
46 Antimetabolites Phase 3,Phase 1,Phase 2
47 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
48 Hormone Antagonists Phase 3,Phase 2,Phase 1
49 Hormones Phase 3,Phase 2,Phase 1
50
Isophosphamide mustard Phase 3,Phase 1,Phase 2 0

Interventional clinical trials:

(show top 50) (show all 57)
# Name Status NCT ID Phase Drugs
1 Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle Unknown status NCT00589537 Phase 3
2 Lerisetron Compared With Granisetron in Preventing Nausea and Vomiting in Men Being Treated With Radiation Therapy for Stage I Seminoma Unknown status NCT00004219 Phase 3 granisetron hydrochloride;lerisetron
3 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
4 Radiation Therapy Compared With Chemotherapy in Treating Patients With Stage I Testicular Cancer Completed NCT00003014 Phase 3 carboplatin
5 Combination Chemotherapy With or Without Bone Marrow or Stem Cell Transplantation in Treating Men With Untreated Germ Cell Tumors Completed NCT00002596 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
6 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
7 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
8 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
9 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
10 Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer Completed NCT00003941 Phase 3 cisplatin;etoposide;ifosfamide
11 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
12 Ondansetron With or Without Dexamethasone to Prevent Vomiting in Patients Receiving Radiation Therapy to the Upper Abdomen Completed NCT00016380 Phase 3 dexamethasone;ondansetron
13 Adjuvant Bleomycin, Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer Recruiting NCT02341989 Phase 3 Bleomycin Etoposide and Cisplatin;Carboplatin
14 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
15 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
16 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
17 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
18 Carboplatin AUC-10 With Early PET Scanning in Metastatic Seminoma Completed NCT02272816 Phase 2 Carboplatin AUC-10
19 ARQ 197 for Subjects With Relapsed or Refractory Germ Cell Tumors Completed NCT01055067 Phase 2 Tivantinib (ARQ 197)
20 Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00957905 Phase 2 Alvocidib Hydrochloride;Fluorouracil;Leucovorin Calcium;Oxaliplatin
21 Docetaxel in Treating Patients With Recurrent or Refractory Germ Cell Cancer Completed NCT00002903 Phase 2 docetaxel
22 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
23 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
24 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
25 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
26 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
27 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
28 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
29 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
30 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
31 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
32 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
33 Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases Completed NCT00154388 Phase 2 Imatinib mesylate
34 Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma Recruiting NCT01887340 Phase 2 Carboplatin;Etoposide;Cisplatin
35 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
36 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2 PD-0332991
37 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
38 Therapy De-escalation in Seminoma Stage IIA/B Active, not recruiting NCT01593241 Phase 2 Carboplatin
39 Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors Active, not recruiting NCT03158064 Phase 2 Durvalumab;Tremelimumab
40 Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma Not yet recruiting NCT03937843 Phase 2 Carboplatin;Cisplatin;Etoposide
41 Imatinib Mesylate in Treating Patients With Progressive, Refractory, or Recurrent Stage II or Stage III Testicular or Ovarian Cancer Terminated NCT00042952 Phase 2 imatinib mesylate
42 Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors Terminated NCT01808534 Phase 2 palifosfamide
43 Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer Completed NCT00060372 Phase 1 ipilimumab;therapeutic allogeneic lymphocytes
44 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
45 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1 lapatinib;paclitaxel
46 Analysis of Transposon Control Pathways in Germinal Cancers of the Testicle Unknown status NCT02873793
47 REtrospective Study of TESTIcular CAncer Patients at the University Magdeburg Completed NCT02092740
48 Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients Completed NCT00705094
49 DNA Analysis in Samples From Younger Patients With Germ Cell Tumors and Their Parents or Siblings Completed NCT01434355
50 Positron Emission Tomography in Detecting Testicle Cancer Completed NCT00045045 Not Applicable

Search NIH Clinical Center for Seminoma

Cochrane evidence based reviews: seminoma

Genetic Tests for Seminoma

Anatomical Context for Seminoma

MalaCards organs/tissues related to Seminoma:

42
Testis, Bone, Lymph Node, Prostate, Bone Marrow, Kidney, Testes

Publications for Seminoma

Articles related to Seminoma:

(show top 50) (show all 1990)
# Title Authors Year
1
Malignant epidural spinal cord compression secondary to testicular cancer (mixed choriocarcinoma and seminoma) in the immediate post radical orchidectomy period. ( 31110723 )
2019
2
Distinct metabolic features of seminoma and embryonal carcinoma revealed by combined transcriptome and metabolome analyses. ( 30835130 )
2019
3
True hermaphroditism with seminoma: A case report. ( 30655982 )
2019
4
Pure Seminoma and Concurrent Aggressive Lymphoma: Case Report of a Patient With Persistent Müllerian Duct Syndrome. ( 30587405 )
2019
5
Mixed germ cell tumor composed of a tridermic testicular teratoma and seminoma in a rooster. ( 30862303 )
2019
6
c-Src Recruitment is Involved in c-MET-Mediated Malignant Behaviour of NT2D1 Non-Seminoma Cells. ( 30646583 )
2019
7
Testicular Seminoma in a Transgender Woman: A Case Report. ( 30650051 )
2019
8
Readressing the rationale of irradiation in stage I seminoma guidelines: a critical essay. ( 30680874 )
2019
9
Re: Exploring the Spectrum of Late Effects following Radical Orchidectomy for Stage I Testicular Seminoma: . ( 30759675 )
2019
10
Positron Emission Tomography-Positive Post-Chemotherapy Seminoma Masses: Time to Reevaluate the Role of Radiotherapy? ( 30811289 )
2019
11
Primary Seminoma Localized in Mediastinum: Case Report. ( 30834006 )
2019
12
Granulomatous CNS inflammation associated with seminoma. ( 30859315 )
2019
13
m6A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance. ( 30866959 )
2019
14
Reclassification of good-risk seminoma: prognostic factors, novel biomarkers and implications for clinical management. ( 30880465 )
2019
15
Adjuvant radiotherapy for Stage I seminoma: A Single-institutional experience. ( 30900627 )
2019
16
Re: New Insights on the Mechanisms Affecting Fertility in Men with Non-Seminoma Testicular Cancer before Cancer Therapy. ( 30917083 )
2019
17
Erratum: Spermatocytic seminoma with rhabdomyoblastic differentiation: Case report and review of literature. ( 30971586 )
2019
18
Reduced semen quality in patients with testicular cancer seminoma is associated with alterations in the expression of sperm proteins. ( 31006710 )
2019
19
Prominent right ventricular mass in a young patient with a history of classic testicular seminoma: a case report. ( 31020243 )
2019
20
Synthesis of a novel platinum(II) complex with 6,7-dichloro-5,8-quinolinedione and the study of its antitumor mechanism in testicular seminoma. ( 31055215 )
2019
21
PET-CT for the management of testicular seminoma patients with post-chemotherapy residual masses. ( 31075095 )
2019
22
Controversies in the management of stage I seminoma: adjuvant carboplatin revisited. ( 29992462 )
2019
23
Seminoma component of mixed testicular germ cell tumor shows a higher incidence of loss of heterozygosity than pure-type seminoma. ( 30266250 )
2019
24
Exploring the spectrum of late effects following radical orchidectomy for stage I testicular seminoma: a systematic review of the literature. ( 30350189 )
2019
25
Mediastinal seminoma presenting as a neck mass falsely diagnosed as anaplastic thyroid carcinoma: A case report. ( 30468316 )
2019
26
CSE1L participates in regulating cell mitosis in human seminoma. ( 30485574 )
2019
27
A Qualitative Analysis of the Impact of Carboplatin AUC 10 on Physical, Work Functioning and Bone Marrow Toxicity Among Seminoma Patients - A Single-centre Experience. ( 30587629 )
2019
28
Paraneoplastic recurrent tumefactive demyelination in a 62-year-old man with metastatic seminoma. ( 30588483 )
2019
29
Ambiguous presentation of an intra-abdominal testicular seminoma in a 40-year-old man: a case report. ( 30609931 )
2019
30
Leptin Receptor as a Potential Target to Inhibit Human Testicular Seminoma Growth. ( 30610844 )
2019
31
Retroperitoneal extragonadal seminoma developed with acute lower inferior vena cava syndrome: A case report. ( 30069432 )
2018
32
Laparoscopic Management of Chylous Leakage Using a Direct Lymph Node Injection with Methylene Blue as a Leakage Point Location Strategy in a Patient with Retroperitoneal Extragonadal Seminoma. ( 30263965 )
2018
33
A Risk-Adapted Approach to Patients with Stage I Seminoma according to the Status of Rete Testis: The Fourth Spanish Germ Cell Cancer Group Study. ( 29587278 )
2018
34
Questioning the Value of Fluorodeoxyglucose Positron Emission Tomography for Residual Lesions After Chemotherapy for Metastatic Seminoma: Results of an International Global Germ Cell Cancer Group Registry. ( 30285559 )
2018
35
Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis. ( 29693409 )
2018
36
Synchronous Leydig Cell Tumor and Seminoma in the Ipsilateral Testis. ( 29670803 )
2018
37
Malignant Sertoli cell tumor of the testis masquerading as seminoma with bone metastasis. ( 30303161 )
2018
38
Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation. ( 30012875 )
2018
39
Peritoneal Myeloid Sarcoma in a Patient Treated for a Testicular Seminoma. ( 29955031 )
2018
40
Persistent Mullerian Duct Syndrome with Testicular Seminoma in Transverse Testicular Ectopia. ( 30568363 )
2018
41
Prognostic factors for tumor recurrence in patients with clinical stage I seminoma undergoing surveillance-A systematic review. ( 28712790 )
2018
42
Cervical mass as the first clinical manifestation of unsuspected metastatic seminoma. ( 28807530 )
2018
43
Testicular orphan receptor 4 promotes tumor progression and implies poor survival through AKT3 regulation in seminoma. ( 29197138 )
2018
44
Testicular seminoma: Scattered radiation dose to the contralateral testis in the modern era. ( 29306641 )
2018
45
Seminoma Metastatic to the Orbit. ( 29334543 )
2018
46
Current Practice Patterns Surrounding Fertility Concerns in Stage I Seminoma Patients: Survey of United States Radiation Oncologists. ( 29336660 )
2018
47
Changing Practice Evaluation-Stage 1 Seminoma: Outcomes With Adjuvant Treatment Versus Surveillance: Risk Factors for Recurrence and Optimizing Follow-up Protocols-Experience From a Supraregional Center. ( 29336917 )
2018
48
Recommendations for followup of stage I and II seminoma: The Princess Margaret Cancer Centre approach. ( 29381453 )
2018
49
Controversies in the Management of Clinical Stage I Seminoma: Carboplatin a Decade in-Time to Start Backing Out. ( 29389229 )
2018
50
Paratesticular seminoma: echographic features and histological diagnosis with review of the literature. ( 29411910 )
2018

Variations for Seminoma

Copy number variations for Seminoma from CNVD:

7 (show all 13)
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 55928 11 56400000 134452384 Loss Seminomas
2 61576 12 1 56300000 Gain Seminomas
3 119165 18 1 15400000 Loss Seminomas
4 120979 18 35500000 76117153 Loss Seminomas
5 138723 2 169500000 182700000 Gain Seminomas
6 146936 2 56300000 182700000 Loss Seminomas
7 157118 21 12300000 46944323 Gain Seminomas
8 160299 22 11800000 49691432 Loss Seminomas
9 217037 7 1 158821424 Gain Seminomas
10 237233 8 2200000 146274826 Gain Seminomas
11 257126 X 1 24900000 Gain Seminomas
12 262546 X 37500000 154913754 Gain Seminomas
13 262571 X 37500000 47300000 Gain Seminomas

Expression for Seminoma

Search GEO for disease gene expression data for Seminoma.

GO Terms for Seminoma

Biological processes related to Seminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide hormone processing GO:0016486 9.16 CGA CGB3
2 female gamete generation GO:0007292 8.96 CGB3 CGB7
3 cell-cell signaling GO:0007267 8.92 CGB3 CGB7 ESR2 FGFR3

Molecular functions related to Seminoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 CGA CGB3 CGB7
2 alkaline phosphatase activity GO:0004035 8.62 ALPG ALPP

Sources for Seminoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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