MCID: SNL003
MIFTS: 22

Senile Angioma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Senile Angioma

MalaCards integrated aliases for Senile Angioma:

Name: Senile Angioma 12 15 71
Senile Naevus of Skin 12
Senile Hemangioma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2495
NCIt 49 C4390
SNOMED-CT 67 5050001
UMLS 71 C0343082

Summaries for Senile Angioma

MalaCards based summary : Senile Angioma, also known as senile naevus of skin, is related to testicular gonadoblastoma and liver fibroma. An important gene associated with Senile Angioma is MIR424 (MicroRNA 424), and among its related pathways/superpathways are MicroRNAs in cancer and Central carbon metabolism in cancer. Affiliated tissues include skin, b cells and endothelial.

Related Diseases for Senile Angioma

Diseases related to Senile Angioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 testicular gonadoblastoma 10.2 VIM KIT
2 liver fibroma 10.2 VIM KIT
3 mast-cell sarcoma 10.2 VIM KIT
4 embryonal sarcoma 10.2 VIM KIT
5 polymorphous low-grade adenocarcinoma 10.2 VIM KIT
6 vaginal endometrial stromal sarcoma 10.2 VIM KIT
7 benign breast phyllodes tumor 10.2 VIM KIT
8 vagina sarcoma 10.2 VIM KIT
9 acral lentiginous melanoma 10.2 VIM KIT
10 pleomorphic liposarcoma 10.2 VIM KIT
11 perineurioma 10.2 VIM KIT
12 b-cell lymphoma 10.2
13 intravascular large b-cell lymphoma 10.2
14 adenosarcoma 10.2 VIM KIT
15 pleomorphic carcinoma 10.2 VIM KIT
16 endodermal sinus tumor 10.2 VIM KIT
17 hemangiopericytoma, malignant 10.2 VIM KIT
18 smooth muscle tumor 10.1 VIM KIT
19 renal oncocytoma 10.1 VIM KIT
20 lentigines 10.1 MAP2K1 KIT
21 cavernous hemangioma 10.1 VIM KIT
22 angiomyolipoma 10.0 VIM KIT
23 fibrous histiocytoma 10.0 VIM KIT
24 mucinous adenocarcinoma 10.0 VIM KIT
25 diffuse large b-cell lymphoma 10.0
26 lymphoma 10.0
27 hemangioma 10.0
28 capillary hemangioma 10.0
29 spasticity 10.0
30 endometrial serous adenocarcinoma 9.9 MIR455 CCNE1
31 neurilemmoma 9.9 VIM KIT
32 oropharynx cancer 9.9 MIR455 KIT
33 xanthomatosis 9.9
34 pancytopenia 9.9
35 malignant fibrous histiocytoma 9.9 VIM KIT
36 fibrosarcoma 9.8 VIM MAP2K1 KIT
37 bladder urothelial carcinoma 9.7 MAP2K1 KIT CCNE1
38 rhabdomyosarcoma 9.7 VIM MAP2K1 KIT
39 neurofibroma 9.7 VIM KIT
40 thoracic cancer 9.6 MIR455 MIR424 MIR130A
41 hematologic cancer 9.1 MIRLET7F1 MIR455 MIR424 KIT
42 leukemia, acute myeloid 9.0 MIR455 MIR424 MIR130A MAP2K1 KIT
43 ovarian cancer 8.7 VIM MIR424 MIR130A MAP2K1 KIT CCNE1
44 hepatocellular carcinoma 8.5 MIR455 MIR424 MIR130A MAP2K1 KIT CCNE1
45 lung cancer 7.9 MIRLET7F1 MIR455 MIR424 MIR130A MAP2K1 KIT

Graphical network of the top 20 diseases related to Senile Angioma:



Diseases related to Senile Angioma

Symptoms & Phenotypes for Senile Angioma

Drugs & Therapeutics for Senile Angioma

Search Clinical Trials , NIH Clinical Center for Senile Angioma

Genetic Tests for Senile Angioma

Anatomical Context for Senile Angioma

MalaCards organs/tissues related to Senile Angioma:

40
Skin, B Cells, Endothelial

Publications for Senile Angioma

Articles related to Senile Angioma:

# Title Authors PMID Year
1
Inhibition of heat shock protein 90 exerts an antitumour effect in angiosarcoma: involvement of the vascular endothelial growth factor signalling pathway. 61
28078663 2017
2
Intravascular large B cell lymphoma with neurological symptoms diagnosed on the basis of a senile angioma-like eruption. 61
21686374 2009
3
Prichard's structures of the fossa ovalis are age-related phenomena composed of nonreplicating endothelial cells: the cardiac equivalent of cutaneous senile angioma. 61
18092955 2007
4
Senile angioma-like eruption: a skin manifestation of intravascular large B cell lymphoma. 61
15316168 2004
5
Intravascular large B cell lymphoma diagnosed by senile angioma biopsy. 61
12583632 2003
6
[Various histological findings in the so-called senile angioma. Phenomenon of the epidermo-dermal surveillance]. 61
4592041 1973
7
[Clinical picture and histology of so-called senile angioma of the free lip edges (Pasini)]. 61
13671883 1959
8
[Senile angioma]. 61
13533048 1958
9
[Clinical features and histology of angioma. III. Histology and pathogenesis of senile angioma]. 61
13198143 1954
10
[On incidence by age of disseminated papuliferous teleangiectases so-called senile angioma]. 61
13039348 1953

Variations for Senile Angioma

Expression for Senile Angioma

Search GEO for disease gene expression data for Senile Angioma.

Pathways for Senile Angioma

Pathways related to Senile Angioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.42 VIM MIRLET7F1 MAP2K1 CCNE1
2 11.17 MAP2K1 KIT
3 11.09 MAP2K1 CCNE1
4 10.93 MAP2K1 CCNE1
5 10.65 MIRLET7F1 CCNE1

GO Terms for Senile Angioma

Biological processes related to Senile Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 gene silencing by miRNA GO:0035195 9.26 MIRLET7F1 MIR455 MIR424 MIR130A
2 Bergmann glial cell differentiation GO:0060020 8.62 VIM MAP2K1

Molecular functions related to Senile Angioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.96 VIM MAP2K1
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 8.8 MIRLET7F1 MIR424 MIR130A

Sources for Senile Angioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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