Aliases & Classifications for Senile Ectropion

MalaCards integrated aliases for Senile Ectropion:

Name: Senile Ectropion 12 15 73
Involutional Ectropion 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13356
ICD9CM 35 374.11
SNOMED-CT 68 71659009
UMLS 73 C0155193

Summaries for Senile Ectropion

MalaCards based summary : Senile Ectropion, also known as involutional ectropion, is related to mid-dermal elastolysis and ectropion. An important gene associated with Senile Ectropion is DNAAF3 (Dynein Axonemal Assembly Factor 3), and among its related pathways/superpathways are Degradation of the extracellular matrix and Proteoglycans in cancer. Affiliated tissues include eye.

Related Diseases for Senile Ectropion

Diseases related to Senile Ectropion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 mid-dermal elastolysis 10.4 ELN MMP7
2 ectropion 10.4
3 optic disk drusen 10.3 ELN KANTR
4 chronic actinic dermatitis 10.3 ELN MMP9
5 aortic valve disease 1 10.2 ELN TWIST1
6 supravalvular aortic stenosis 10.2 ELN MMP2
7 apical myocardial infarction 10.2 KANTR MMP2
8 hypertelorism 10.2 ELN TWIST1
9 hemidystonia 10.2 KANTR TWIST1
10 brain glioblastoma multiforme 10.1 MMP7 MMP9
11 pediatric multiple sclerosis 10.1 MMP7 MMP9
12 extracranial arteriovenous malformation 10.1 MMP2 MMP9
13 adult astrocytic tumour 10.1 MMP7 MMP9
14 lentigo maligna melanoma 10.1 MMP2 MMP9
15 villous adenocarcinoma 10.1 MMP2 MMP9
16 psammomatous meningioma 10.1 MMP2 MMP9
17 acute transverse myelitis 10.1 MMP2 MMP9
18 pelvic organ prolapse 10.1 ELN MMP9
19 ischemic colitis 10.1 MMP2 MMP9
20 parotitis 10.0 MMP2 MMP9
21 conjunctival nevus 10.0 MMP2 MMP9
22 klatskin's tumor 10.0 MMP2 MMP9
23 entropion 10.0
24 microcystic meningioma 10.0 MMP2 MMP9
25 adenomyosis 10.0 MMP2 MMP9
26 corneal ulcer 10.0 MMP2 MMP9
27 nasal cavity squamous cell carcinoma 10.0 MMP2 MMP9
28 odontogenic myxoma 10.0 MMP2 MMP9
29 transverse myelitis 10.0 MMP2 MMP9
30 pulmonary emphysema 10.0 ELN MMP9
31 lung giant cell carcinoma 10.0 MMP2 MMP9
32 orthostatic intolerance 10.0 ELN KANTR
33 eyelid disease 9.9 DOCK8 LAX1
34 hypertensive heart disease 9.9 MMP2 MMP9
35 spastic ectropion 9.9 KANTR LAX1
36 bowen's disease 9.9
37 tongue cancer 9.9 MMP2 MMP9
38 senile entropion 9.9 KANTR LAX1
39 cicatricial ectropion 9.9 KANTR LAX1
40 marfan syndrome 9.8 ELN MMP2
41 grade iii astrocytoma 9.7 MMP2 MMP9
42 blepharochalasis 9.7 LAX1 MMP9
43 hypertropia 9.7 KANTR LAX1
44 sorsby fundus dystrophy 9.7 ELN MMP2 MMP9
45 aortic aneurysm, familial thoracic 1 9.7 ELN MMP2 MMP9
46 pneumothorax 9.7 ELN MMP2 MMP9
47 aortic disease 9.7 ELN MMP2 MMP9
48 inguinal hernia 9.7 ELN MMP2 MMP9
49 aortic aneurysm, familial abdominal, 1 9.7 ELN MMP2 MMP9
50 fundus dystrophy 9.6 ELN MMP2 MMP9

Graphical network of the top 20 diseases related to Senile Ectropion:



Diseases related to Senile Ectropion

Symptoms & Phenotypes for Senile Ectropion

Drugs & Therapeutics for Senile Ectropion

Search Clinical Trials , NIH Clinical Center for Senile Ectropion

Genetic Tests for Senile Ectropion

Anatomical Context for Senile Ectropion

MalaCards organs/tissues related to Senile Ectropion:

41
Eye

Publications for Senile Ectropion

Articles related to Senile Ectropion:

# Title Authors Year
1
Senile ectropion. ( 3347680 )
1988
2
Senile ectropion. ( 974868 )
1976
3
Senile ectropion and entropion: a comparative histopathological study. ( 57735 )
1976
4
Surgery of senile ectropion and entropion. ( 5012696 )
1972
5
Senile ectropion. ( 13959048 )
1962
6
V-Z procedure for the correction of senile ectropion. ( 13840478 )
1959
7
Senile ectropion: analysis of types and surgical correction. ( 13207288 )
1954
8
Senile ectropion and Bowen's disease. ( 21066076 )
1946
9
SUBCUTANEOUS SPLITTING OF THE LID IN THE OPERATIVE TREATMENT OF SENILE ECTROPION*. ( 18170136 )
1945

Variations for Senile Ectropion

Expression for Senile Ectropion

Search GEO for disease gene expression data for Senile Ectropion.

Pathways for Senile Ectropion

Pathways related to Senile Ectropion according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.36 ELN MMP2 MMP7 MMP9
2 11.99 MMP2 MMP9 TWIST1
3 11.85 MMP2 MMP7 MMP9
4 11.6 MMP2 MMP9 TWIST1
5
Show member pathways
11.49 MMP2 MMP7 MMP9
6 11.4 MMP2 MMP9
7
Show member pathways
11.38 MMP2 MMP9
8 11.38 MMP2 MMP7 MMP9
9 11.25 MMP2 MMP9
10
Show member pathways
11.21 MMP2 MMP9
11 11.15 MMP2 MMP7 MMP9
12 11.14 ELN MMP9
13 11.07 MMP2 MMP9
14 11.03 MMP2 MMP9
15 10.93 ELN MMP2 MMP9
16 10.91 MMP2 MMP9
17 10.84 MMP2 MMP9
18 10.66 MMP7 MMP9
19 10.58 MMP2 MMP7 MMP9

GO Terms for Senile Ectropion

Cellular components related to Senile Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 8.92 ELN MMP2 MMP7 MMP9

Biological processes related to Senile Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.54 MMP2 MMP9 TWIST1
2 embryo implantation GO:0007566 9.32 MMP2 MMP9
3 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.26 MMP2 MMP9
4 endodermal cell differentiation GO:0035987 9.16 MMP2 MMP9
5 collagen catabolic process GO:0030574 9.13 MMP2 MMP7 MMP9
6 extracellular matrix disassembly GO:0022617 8.92 ELN MMP2 MMP7 MMP9

Molecular functions related to Senile Ectropion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.33 MMP2 MMP7 MMP9
2 metallopeptidase activity GO:0008237 9.13 MMP2 MMP7 MMP9
3 metalloendopeptidase activity GO:0004222 8.8 MMP2 MMP7 MMP9

Sources for Senile Ectropion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....