MCID: SNS026
MIFTS: 22

Sensory System Disease

Categories: Neuronal diseases, Smell/Taste diseases

Aliases & Classifications for Sensory System Disease

MalaCards integrated aliases for Sensory System Disease:

Name: Sensory System Disease 12 15 17

Classifications:



External Ids:

Disease Ontology 12 DOID:0050155

Summaries for Sensory System Disease

Disease Ontology : 12 A nervous system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell).

MalaCards based summary : Sensory System Disease is related to auditory system disease and leber congenital amaurosis with early-onset deafness. An important gene associated with Sensory System Disease is CRYAA (Crystallin Alpha A), and among its related pathways/superpathways is MicroRNAs in cancer.

Related Diseases for Sensory System Disease

Diseases related to Sensory System Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 325)
# Related Disease Score Top Affiliating Genes
1 auditory system disease 32.4 SERPINA3 MIR96 ERCC6 EPRS1
2 leber congenital amaurosis with early-onset deafness 11.0
3 muscle tissue disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR199A1 MIR142 MIR126
4 eye degenerative disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR17 KDM4C
5 uveal disease 10.7 VEGFA U2AF1 SERPINA3 MIR9-1 MIR199A1 MIR142
6 x-linked recessive disease 10.7 U2AF1 SERPINA3 PRODH MIR142 ICOSLG H2AC18
7 autoimmune disease of musculoskeletal system 10.7 SERPINA3 MIR21 MIR199A1 MIR17 MIR142 MIR126
8 x-linked monogenic disease 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR142 ICOSLG
9 pancreas disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
10 autoimmune disease of the nervous system 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR142 MIR126
11 autoimmune disease of central nervous system 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR142 MIR126
12 upper respiratory tract disease 10.7 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17 MIR142
13 gastrointestinal system benign neoplasm 10.7 SERPINA3 MIR21 MIR199A1 MIR17 MIR142 H2AC18
14 stomach disease 10.7 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17 MIR142
15 muscular disease 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR21 MIR199A1
16 female reproductive system disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
17 immune deficiency disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
18 overnutrition 10.7 SERPINA3 PRODH MIR21 MIR199A1 MIR17 MIR142
19 central nervous system disease 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR21 MIR199A1
20 bone inflammation disease 10.7 VEGFA SERPINA3 MIR21 MIR199A1 MIR17 MIR142
21 intestinal benign neoplasm 10.7 VEGFA SERPINA3 MIR21 MIR199A1 MIR17 MIR142
22 uterine anomalies 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
23 nervous system disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR96 MIR9-1
24 skin disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
25 ovary epithelial cancer 10.7 VEGFA U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1
26 arteries, anomalies of 10.7 VEGFA SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
27 eye disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
28 autosomal genetic disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
29 respiratory system cancer 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
30 reproductive system disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
31 contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
32 malignant ovarian surface epithelial-stromal neoplasm 10.7 VEGFA SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
33 disease by infectious agent 10.7 SERPINA3 PRODH MIR9-1 MIR21 MIR199A1 MIR17
34 peripheral nervous system disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
35 leukocyte disease 10.7 VEGFA U2AF1 SERPINA3 MIR21 MIR199A1 MIR17
36 bladder disease 10.7 U2AF1 MIR96 MIR9-1 MIR21 MIR199A1 MIR17
37 bile duct disease 10.7 SERPINA3 MIR9-1 MIR199A1 MIR17 MIR142 KDM4C
38 chromosomal duplication syndrome 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR126 KDM4C
39 urinary system disease 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR21 MIR199A1
40 colonic disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
41 mature b-cell neoplasm 10.7 U2AF1 MIR9-1 MIR199A1 MIR17 MIR142 MIR126
42 glucose metabolism disease 10.7 VEGFA SERPINA3 PRODH MIR9-1 MIR21 MIR199A1
43 inherited metabolic disorder 10.7 SERPINA3 PRODH MIR9-1 MIR21 MIR199A1 MIR17
44 autosomal recessive disease 10.7 U2AF1 SERPINA3 PRODH ICOSLG H2AC18 ERCC6
45 chromosomal disease 10.7 U2AF1 SERPINA3 PRODH MIR9-1 MIR21 MIR17
46 endocrine system disease 10.7 U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1 MIR17
47 connective tissue disease 10.7 VEGFA U2AF1 SERPINA3 PRODH MIR9-1 MIR21
48 endocrine gland cancer 10.7 SERPINA3 MIR96 MIR9-1 MIR21 MIR199A1 MIR17
49 connective tissue cancer 10.7 VEGFA U2AF1 SERPINA3 MIR9-1 MIR21 MIR199A1
50 cervix disease 10.7 MIR9-1 MIR21 MIR199A1 MIR17 MIR142 MIR126

Graphical network of the top 20 diseases related to Sensory System Disease:



Diseases related to Sensory System Disease

Symptoms & Phenotypes for Sensory System Disease

Drugs & Therapeutics for Sensory System Disease

Search Clinical Trials , NIH Clinical Center for Sensory System Disease

Genetic Tests for Sensory System Disease

Anatomical Context for Sensory System Disease

Publications for Sensory System Disease

Articles related to Sensory System Disease:

# Title Authors PMID Year
1
X-linked infantile periodic alternating nystagmus. 61
16020310 2005

Variations for Sensory System Disease

Expression for Sensory System Disease

Search GEO for disease gene expression data for Sensory System Disease.

Pathways for Sensory System Disease

Pathways related to Sensory System Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.72 VEGFA MIR96 MIR9-1 MIR21 MIR199A1 MIR17

GO Terms for Sensory System Disease

Biological processes related to Sensory System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.65 VEGFA MIR21 MIR126
2 positive regulation of protein kinase B signaling GO:0051897 9.62 VEGFA MIR21 MIR199A1 MIR126
3 positive regulation of endothelial cell migration GO:0010595 9.58 VEGFA MIR21 MIR199A1
4 positive regulation of angiogenesis GO:0045766 9.56 VEGFA MIR21 MIR199A1 MIR126
5 positive regulation of cardiac muscle hypertrophy in response to stress GO:1903244 9.46 MIR199A1 MIR17
6 miRNA mediated inhibition of translation GO:0035278 9.46 MIR17 MIR21 MIR9-1 MIR96
7 positive regulation of metalloendopeptidase activity GO:1904685 9.43 MIR21 MIR17
8 negative regulation of vascular associated smooth muscle cell apoptotic process GO:1905460 9.37 MIR21 MIR17
9 gene silencing by miRNA GO:0035195 9.17 MIR126 MIR142 MIR17 MIR199A1 MIR21 MIR9-1
10 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:1903589 9.13 MIR126 MIR21 VEGFA

Molecular functions related to Sensory System Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mRNA 3'-UTR binding GO:0003730 9.35 MIR9-1 MIR21 MIR17 MIR142 MIR126
2 mRNA binding involved in posttranscriptional gene silencing GO:1903231 9.17 MIR126 MIR142 MIR17 MIR199A1 MIR21 MIR9-1

Sources for Sensory System Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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