MCID: SPT023
MIFTS: 22

Septate Uterus

Categories: Fetal diseases, Rare diseases, Reproductive diseases
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Aliases & Classifications for Septate Uterus

MalaCards integrated aliases for Septate Uterus:

Name: Septate Uterus 58 75 33

Classifications:

Orphanet: 58  
Rare infertility disorders
Rare gynaecological and obstetric diseases
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 32 Q51.2
UMLS via Orphanet 72 C0152240
Orphanet 58 ORPHA180122
ICD11 33 1959106408

Summaries for Septate Uterus

MalaCards based summary: Septate Uterus is related to complete septate uterus and partial septate uterus. The drugs Hyaluronic acid and Adjuvants, Immunologic have been mentioned in the context of this disorder. Affiliated tissues include uterus, cervix and placenta.

Related Diseases for Septate Uterus

Diseases related to Septate Uterus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 64)
# Related Disease Score Top Affiliating Genes
1 complete septate uterus 11.6
2 partial septate uterus 11.6
3 longitudinal vaginal septum 11.3
4 septate vagina 10.8
5 infertility 10.7
6 uterine anomalies 10.5
7 pregnancy loss, recurrent 1 10.5
8 endometriosis 10.4
9 renal hypodysplasia/aplasia 1 10.4
10 bicornuate uterus 10.4
11 amenorrhea 10.3
12 suppressor of tumorigenicity 3 10.2
13 cervical cancer 10.2
14 leiomyoma 10.2
15 adhesions of uterus 10.2
16 double uterus-hemivagina-renal agenesis 10.2
17 transverse vaginal septum 10.2
18 down syndrome 10.1
19 endometrial cancer 10.1
20 myoma 10.1
21 vaginal discharge 10.1
22 placenta accreta 10.1
23 asherman's syndrome 10.1
24 renal dysplasia 10.1
25 diaphragmatic hernia, congenital 10.0
26 leiomyoma, uterine 10.0
27 constricting bands, congenital 10.0
28 gastroschisis 10.0
29 hydatidiform mole, recurrent, 1 10.0
30 spastic ataxia, charlevoix-saguenay type 10.0
31 mayer-rokitansky-kuster-hauser syndrome 10.0
32 ataxia with vitamin e deficiency 10.0
33 otopalatodigital syndrome, type ii 10.0
34 otopalatodigital syndrome, type i 10.0
35 adenomyosis 10.0
36 spastic paraplegia, ataxia, and mental retardation 10.0
37 chromosome 16p13.3 deletion syndrome, proximal 10.0
38 leukemia, acute lymphoblastic 10.0
39 leukemia, acute lymphoblastic 3 10.0
40 tuberculous salpingitis 10.0
41 omphalocele 10.0
42 ectopic pregnancy 10.0
43 b-lymphoblastic leukemia/lymphoma 10.0
44 pre-eclampsia 10.0
45 polycystic ovary syndrome 10.0
46 vaginal cancer 10.0
47 male infertility 10.0
48 cystadenoma 10.0
49 endometrial adenocarcinoma 10.0
50 adenocarcinoma 10.0

Graphical network of the top 20 diseases related to Septate Uterus:



Diseases related to Septate Uterus

Symptoms & Phenotypes for Septate Uterus

Drugs & Therapeutics for Septate Uterus

Drugs for Septate Uterus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
2 Adjuvants, Immunologic
3 Viscosupplements
4 Immunologic Factors
5 Protective Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prevention of Intrauterine Adhesions After Hysteroscopic Metroplasty With Autocross-linked Hyaluronic Acid Gel Unknown status NCT02404454

Search NIH Clinical Center for Septate Uterus

Genetic Tests for Septate Uterus

Anatomical Context for Septate Uterus

Organs/tissues related to Septate Uterus:

MalaCards : Uterus, Cervix, Placenta, Ovary, Endothelial

Publications for Septate Uterus

Articles related to Septate Uterus:

(show top 50) (show all 490)
# Title Authors PMID Year
1
The association between congenital uterine anomalies and perinatal outcomes - does type of defect matters? 62
34238096 2022
2
Impact of concomitant intrauterine adhesions on pregnancy outcomes and obstetric complications in women with a septate uterus. 62
35574630 2022
3
Role of Laparoscopic Transillumination Guidance During Hysteroscopic Metroplasty in Simplifying Surgical Management of Type II Robert's Uterus. 62
36457422 2022
4
Septum Resection Prior to In Vitro Fertilization-Embryo Transfer: A Retrospective Controlled Study. 62
36394304 2022
5
Reproductive outcomes after uterine septum resection in patients with recurrent miscarriage or infertility: a retrospective study in Chinese women. 62
36217037 2022
6
Reproductive outcomes of natural pregnancy after hysteroscopic septum resection in patients with a septate uterus: a systematic review and meta-analysis. 62
36220552 2022
7
Diagnosis and Management of Mullerian Anomalies Across Differing Resource Settings: Worldwide Adaptations. 62
35489471 2022
8
Septate Uterus. Resect or not? That is Not the Only Question. 62
36037812 2022
9
[New perspectives on diagnostic criteria for septate uterus]. 62
36177577 2022
10
Prevalence of and risk factors for chronic endometritis in patients with intrauterine disorders after hysteroscopic surgery. 62
35718544 2022
11
Ultrasound combined with hysteroscopy for optimum treatment of Robert's uterus: a case report and a review. 62
35934693 2022
12
Preliminary application of three-dimensional printing in congenital uterine anomalies based on three-dimensional transvaginal ultrasonographic data. 62
35836228 2022
13
Surgical disorders in pediatric and adolescent gynecology: Vaginal and uterine anomalies. 62
35880405 2022
14
3D transvaginal ultrasound diagnosis of uterine septa according to different classifications: are there other measurements that correlate to reproductive outcome in small indentation length? 62
35781109 2022
15
Uterine Septum with or without Hysteroscopic Metroplasty: Impact on Fertility and Obstetrical Outcomes-A Systematic Review and Meta-Analysis of Observational Research. 62
35743362 2022
16
Robert's uterus (asymmetric septate uterus): a rare congenital Müllerian duct anomaly. 62
35523517 2022
17
Prevalence and risk factors of intrauterine adhesions in women with a septate uterus: a retrospective cohort study. 62
35361544 2022
18
Perinatal outcomes of women with Müllerian anomalies. 62
35426514 2022
19
Incidence of congenital uterine abnormalities in polycystic ovarian syndrome (CONUTA Study). 62
35219169 2022
20
A "cluster" of ten uterine anomalies observed in a single center over a short period of 4 weeks: a case series. 62
35365244 2022
21
Effect of Hysteroscopic Metroplasty on Reproductive Outcomes in Women with Septate Uterus: Systematic Review and Meta-Analysis. 62
34648934 2022
22
Uterine septum and reproductive outcome. From diagnosis to treatment. How, why, when? 62
35373545 2022
23
A rare variant of obstructed hemivagina and ipsilateral renal agenesis and its improvement of classification. 62
35014127 2022
24
Impact of uterine malformations on pregnancy and neonatal outcomes of IVF/ICSI-frozen embryo transfer. 62
35048124 2022
25
Office hysteroscopic metroplasty with diode laser for septate uterus: a multicenter cohort study. 62
33090039 2022
26
Fertility and pregnancy outcomes following hysteroscopic metroplasty of uterine septa. 62
33306286 2022
27
Effect of hyteroscopic uterine septum resection on pregnancy outcomes. 62
34852309 2022
28
Laparo-Endoscopic Single Site Combined With Hysteroscopy to Diagnose and Treat Robert's Uterine Malformation: A Case Report. 62
35774386 2022
29
MRI Evaluation of Mullerian Duct Anomalies: Practical Classification by the New ASRM System. 62
36388626 2022
30
Cervical Cancer in a Septate Uterus with Double Cervix and Double Vagina: A Case Report and Review of the Literature. 62
35300285 2022
31
Diagnosing Septate Uterus Using Three-Dimensional Ultrasound Using Three Different Classifications: An Interobserver and Intraobserver Agreement Study. 62
34933384 2021
32
Effect of hysteroscopic septum resection on subsequent in vitro fertilization-intracytoplasmic sperm injection outcomes in cases of primary infertility. 62
33872814 2021
33
Müllerian Duct Anomalies: Role in Fertility and Pregnancy. 62
34597219 2021
34
Imaging features of Robert's uterus: Case series of a rare Mullerian duct anomaly. 62
34313499 2021
35
Prevalence and Pregnancy Outcome of Mullerian Anomalies in Infertile Women: A Retrospective Study. 62
35197690 2021
36
Prevalence of T-shaped uterus among fertile women based on ESHRE/ESGE and Congenital Uterine Malformation by Experts (CUME) criteria. 62
34281787 2021
37
Daily practice management of septate uterus: reproductive outcome after septoplasty. 62
34555879 2021
38
Three degrees of separation: complete uterine and cervical septa. 62
34016433 2021
39
The septate uterus and metroplasty-another dogma under siege. 62
34364675 2021
40
Inappropriate surgery in a patient with misdiagnosed Robert's uterus. 62
34217289 2021
41
A comparison of four systems for uterine septum diagnosis and indication for surgical correction. 62
34008393 2021
42
A case of successful pregnancy in a septate uterus after discharge of decidual tissue in the second trimester. 62
33936699 2021
43
Clinical characteristics and management of patients with complete septate uterus, double cervix, obstructed hemivagina, and ipsilateral renal agenesis. 62
33410178 2021
44
Septum resection versus expectant management in women with a septate uterus: an international multicentre open-label randomized controlled trial. 62
33793794 2021
45
'It's all too much'†: the shadow of overtreatment looms over hysteroscopic metroplasty for septate uterus. 62
33793818 2021
46
Ultrasound at the intersection of art, science and technology: complete septate uterus with longitudinal vaginal septum. 62
33646634 2021
47
Critical Role of 3D ultrasound in the diagnosis and management of Robert's uterus: a single-centre case series and a review. 62
33889860 2021
48
A Prospective Randomized Comparative Clinical trial of Hysteroscopic Septal Resection Using Conventional Resectoscope Versus Mini-resectoscope. 62
34083994 2021
49
Uterine Fundus Remodeling after Hysteroscopic Metroplasty: A Prospective Pilot Study. 62
33445663 2021
50
Pregnancy Outcomes in Women With a History of Recurrent Early Pregnancy Loss and a Septate Uterus, With and Without Hysteroscopic Metroplasty. 62
33214519 2020

Variations for Septate Uterus

Expression for Septate Uterus

Search GEO for disease gene expression data for Septate Uterus.

Pathways for Septate Uterus

GO Terms for Septate Uterus

Sources for Septate Uterus

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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