Septate Vagina disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Orphanet: ⁵⁸ A rare vaginal malformation characterized by the presence of a complete or incomplete longitudinal or transverse septum in the vagina due to disrupted fusion or canalization of the solid vaginal plate during embryogenesis. Signs and symptoms depend on the type of septum.

MalaCards based summary: Septate Vagina, also known as congenital duplication of vagina, is related to camptobrachydactyly and hypomelia with mullerian duct anomalies. An important gene associated with Septate Vagina is WT1 (WT1 Transcription Factor). Affiliated tissues include uterus, cervix and colon.

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Related Diseases for Septate Vagina

Diseases related to Septate Vagina via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)

#	Related Disease	Score
1	camptobrachydactyly	11.3
2	hypomelia with mullerian duct anomalies	11.2
3	uterus bicornis bicollis with partial vaginal septum and unilateral hematocolpos with ipsilateral renal agenesis	11.2
4	meacham winn culler syndrome	11.2
5	meacham syndrome	11.2
6	diethylstilbestrol syndrome	11.1
7	endometriosis	10.4
8	double uterus-hemivagina-renal agenesis	10.4
9	infertility	10.4
10	complete septate uterus	10.3
11	transverse vaginal septum	10.2
12	longitudinal vaginal septum	10.2
13	vaginal discharge	10.2
14	anus, imperforate	10.2
15	didelphys uterus	10.2
16	septate uterus	10.2
17	leiomyoma	10.0
18	heart septal defect	10.0
19	adenomyoma	10.0
20	cystadenocarcinoma	10.0
21	appendix adenocarcinoma	10.0
22	renal hypodysplasia/aplasia 1	10.0
23	uterine anomalies	10.0
24	mckusick-kaufman syndrome	10.0
25	polydactyly	10.0
26	renal hypodysplasia/aplasia 3	10.0
27	gynatresia	10.0
28	urinary tract obstruction	10.0
29	uterovaginal malformation	10.0
30	bicornuate uterus	10.0
31	vaginal atresia	10.0
32	anorectal anomalies	9.9
33	cleft palate, isolated	9.9
34	coarctation of aorta	9.9
35	polydactyly, postaxial, type a1	9.9
36	pelvic organ prolapse	9.9
37	chromosome 2q35 duplication syndrome	9.9
38	thrombophilia due to thrombin defect	9.9
39	hypothyroidism, congenital, nongoitrous, 1	9.9
40	ataxia with vitamin e deficiency	9.9
41	deficiency anemia	9.9
42	fibroma	9.9
43	keratomalacia	9.9
44	pulmonary edema	9.9
45	polycystic ovary syndrome	9.9
46	potter's syndrome	9.9
47	squamous cell carcinoma	9.9
48	atrial heart septal defect	9.9
49	cerebral palsy	9.9
50	papillary cystadenocarcinoma	9.9

Graphical network of the top 20 diseases related to Septate Vagina:

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Symptoms & Phenotypes for Septate Vagina

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Drugs & Therapeutics for Septate Vagina

Search Clinical Trials, NIH Clinical Center for Septate Vagina

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Genetic Tests for Septate Vagina

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Anatomical Context for Septate Vagina

Organs/tissues related to Septate Vagina:

MalaCards : Uterus, Cervix, Colon, Kidney, Lymph Node, Placenta, Heart

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Publications for Septate Vagina

Articles related to Septate Vagina:

(show top 50) (show all 674)

#	Title	Authors	PMID	Year
1	U2bC1V2: A Rare Mullerian Abnormality-Complete Uterine Septum, Double Cervix and Complete Vertical Vaginal Septum. ⁶²	Tyagi S...Bhagat S	36457442	2022
2	Vaginoscopic incision of an oblique vaginal septum before menarche. ⁶²	Yu Y...Xu D	36396580	2022
3	Case series: Interdigitating "Y" flap for transverse vaginal septum management. ⁶²	Priyatini T...Meutia AP	36270208	2022
4	Management of an isolated complete imperforate transverse vaginal septum: A case report. ⁶²	Barut A...Yusuf K	36265424	2022
5	Herlyn-Werner-Wunderlich Syndrome: Case Report and Review of the Literature. ⁶²	Panaitescu AM...Gica N	36292155	2022
6	Successful vaginoscopic excision of the vaginal septum in a virgin girl of obstructed hemivagina and ipsilateral renal anomaly: Case report and review of literature. ⁶²	Yamada Y...Kimura F	36245420	2022
7	A rare case of a double vagina in a young American Staffordshire Terrier bitch (Canis lupus familiaris). A case report. ⁶²	Vasiu I...Ober CA	36283129	2022
8	Vaginoscopic Incision of Vaginal Septum With Preservation of the Hymen in a Child With Obstructed Hemi-Vagina Ipsilateral Renal Agenesis (OHVIRA) Syndrome. ⁶²	Moneir WM...Alaqeel A	36407203	2022
9	Forty-two normomenstruating adolescents with Müllerian obstructive anomalies: Presentation, pitfalls in the dagnosis and surgical management. ⁶²	Fontana E...Candiani M	36285343	2022
10	Mayer-Rokitansky-Kuster-Hauser Syndrome: A rare case report from Nepal. ⁶²	Ray U...Gautam B	36268332	2022
11	A case of didelphys uterus: tackling the double trouble adenomyosis and infertility. ⁶²	Bindra V...Madhavi N	35953315	2022
12	Young adolescent with trisomy 13. ⁶²	Kramer BCE...van den Elzen APM	36150723	2022
13	Adolescent abdominal pain due to rare mullerian duct anomaly. ⁶²	Ball S...Fisher J	35780004	2022
14	Conservative Treatment of Didelphyc Uterus with Obstructed Hemivagina and Ipsilateral Renal Agenesis. ⁶²	Candiani M...Parazzini F	35550857	2022
15	Treatment of Urethral Intercourse and Impact on Female Sexual Function. ⁶²	Djordjevic ML...Purohit R	35636278	2022
16	The Impact of Uterus Didelphys on Fertility and Pregnancy. ⁶²	Cwiertnia A...Cymbaluk-Ploska A	36078286	2022
17	Asymptomatic microperforated transverse vaginal septum. ⁶²	Freixo M...Oliveira C	34689698	2022
18	Surgical disorders in pediatric and adolescent gynecology: Vaginal and uterine anomalies. ⁶²	Mentessidou A...Mirilas P	35880405	2022
19	Complete uterine septum involving cervix with unilateral external cervical os stenosis: diagnosis and management. ⁶²	Kashyap N...Xu D	34700004	2022
20	Laparoscopic excision and repair of a cesarean scar pregnancy in a woman with uterine didelphys: a case report. ⁶²	Park SE...Jang TK	35570649	2022
21	Neonatal hydrocolpos presenting as a rapidly progressive abdominal mass with inferior caval vein syndrome. ⁶²	Nowacki RME...Leroy PLJM	35504669	2022
22	Resection of vaginal septum using endoscopic-guided sealing devices in female dogs: 8 cases (2015-2018). ⁶²	Nicoli S...Caccamo R	34937121	2022
23	Isolated recto-vaginal septum injury during parturition: Single-center experience. ⁶²	Altintoprak F...Akin E	35485555	2022
24	Hymen conservative techniques for vaginal surgery - a practical approach. ⁶²	Sleiman Z...Buzzaccarini G	35388280	2022
25	Transverse Vaginal Septum Resection: Technique, Timing, and the Utility of Dilation. A Scoping Review of the Literature. ⁶²	Brander EPA...McQuillan SK	34517117	2022
26	Image-Guided Transvaginal and Transabdominal Drain Placement for Surgical Navigation in a Patient with Tubo-Ovarian Abscess and Obstructed Hemivagina and Ipsilateral Renal Anomaly Syndrome. ⁶²	Parker PB...Lee DM	34289429	2022
27	The Role of Magnetic Resonance Imaging in the Planning of Surgical Treatment of Deep Pelvic Endometriosis. ⁶²	Manti F...Lagana D	35836610	2022
28	Uterus didelphys with double vagina diagnosed during third cesarean section: A case report. ⁶²	Dorji N...Wangden T	35070320	2022
29	Robotic management of congenital urethra-vaginal fistula with transverse vaginal septum. ⁶²	Darga SL...Enganti B	34735094	2022
30	Aqueous vaginal contrast and scheduled hematocolpos with magnetic resonance imaging to delineate complex müllerian anomalies. ⁶²	Romanski PA...Pfeifer SM	34548169	2022
31	Case report: Hydrometrocolpos conditioning recurrent urinary tract infections. ⁶²	Malanowska E...Rubilotta E	36303849	2022
32	Cervical Cancer in a Septate Uterus with Double Cervix and Double Vagina: A Case Report and Review of the Literature. ⁶²	Gong Y...Sui L	35300285	2022
33	Familial occurrence of concomitant imperforate hymen and transverse vaginal septum: a case report. ⁶²	Aboueddahab Z...Kouach J	36284573	2022
34	Multimodal ultrasound imaging of persistent urogenital sinus with uterus didelphys and double vagina malformation: A case report. ⁶²	Wang Y...Wang H	34967392	2021
35	Nerve-sparing laparoscopic disc excision of deep endometriosis involving the bowel: a single-center experience on 371 consecutives cases. ⁶²	Ceccaroni M...Ruffo G	33052528	2021
36	A rare case of symptomatic hydrometrocolpos in a 5y old female. ⁶²	Nassar H...Gobet R	34386351	2021
37	A challenging diagnosis and management of Herlyn-Werner-Wunderlich Syndrome in low-resource Settings: A case report complicated with hydronephrosis. ⁶²	Jomaa S...Tawashi N	34540220	2021
38	Multiple variants of obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome - one clinical center case series and the systematic review of 734 cases. ⁶²	Kudela G...Koszutski T	34274235	2021
39	ADAMTS18 regulates vaginal opening through influencing the fusion of Mullerian duct and apoptosis of vaginal epithelial cells in mice. ⁶²	Lin X...Zhang W	34271244	2021
40	Surgical management of recto-vaginal fistula (about 6 cases). ⁶²	El Karouachi A...Chehab F	34450532	2021
41	Hysteroscopic Management of an Oblique Vaginal Septum with Diverticulum in Herlyn-Werner-Wunderlich Syndrome. ⁶²	Zhang ?? H...Pan ??? H	33775924	2021
42	Herlyn-Werner-Wunderlich syndrome and its complications: A report of two cases and literature review. ⁶²	Li X...Li L	34194598	2021
43	The step-by-step hysteroscopic treatment of patients with vaginal and complete uterine septum with double cervix (U2bC2V1). ⁶²	Di Spiezio Sardo A...Grimbizis G	33975726	2021
44	Congenital anomalies causing hemato/hydrocolpos: imaging findings, treatments, and outcomes. ⁶²	Tanitame K...Ohtsu K	33840015	2021
45	Vaginoscopic Incision of Oblique Vaginal Septum in an Adolescent Girl with OHVIRA Syndrome: Simple Management of Complicated Anomaly. ⁶²	Nigam A...Jain A	34759623	2021
46	Herlyn-Werner-Wunderlich syndrome: Report of a delayed diagnosed case with video presentation of the operative technique of vaginal septum resection. ⁶²	Pittokopitou S...Domali E	33723897	2021
47	Transverse vaginal septum managed by simple flap surgery technique: A case report. ⁶²	Moegni F...Rustamadji P	34062358	2021
48	REDESCRIPTION OF CATHARIOTREMA SELACHII (MACCALLUM, 1916) JOHNSTON AND TIEGS, 1922 (MONOGENOIDEA: MONOCOTYLIDAE), EMENDATION OF MONOTYPIC CATHARIOTREMA JOHNSTON AND TIEGS, 1922, AND PROPOSAL OF CATHARIOTREMATINAE N. SUBFAM. BASED ON MORPHOLOGICAL AND NUCLEOTIDE EVIDENCE. ⁶²	Bullard SA...Dutton HR	34153096	2021
49	Acute abdomen: Unusual presentation of Herlyn-Werner Wunderlich syndrome. ⁶²	Saleh A...Al Hindi S	33962268	2021
50	Robot-assisted laparoscopic hysterectomy for endometrial cancer in a patient with Herlyn-Werner-Wunderlich syndrome. ⁶²	Kobayashi M...Adachi H	34011660	2021

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Genes for Septate Vagina

Genes related to Septate Vagina (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	WT1	WT1 Transcription Factor	Protein Coding	7.86	GeneCards inferred via : Disorders (show sections)

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Variations for Septate Vagina

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Expression for Septate Vagina

Search GEO for disease gene expression data for Septate Vagina.

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Pathways for Septate Vagina

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GO Terms for Septate Vagina

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Sources for Septate Vagina

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: SPT015 MIFTS: 24	Septate Vagina Categories: Fetal diseases, Rare diseases, Reproductive diseases	Data Licensing For inquiries, contact: [email protected]
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