MCID: SRP002
MIFTS: 24

Serpiginous Choroiditis

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Serpiginous Choroiditis

MalaCards integrated aliases for Serpiginous Choroiditis:

Name: Serpiginous Choroiditis 52 58 71
Geographic Helicoid Peripapillary Choroidopathy 52 58
Geographic Serpiginous Choroiditis 52
Peripapillary Choriopathy 52
Serpiginous Choroidopathy 52
Geographic Choroiditis 52

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

ICD10 via Orphanet 33 H30.8
UMLS via Orphanet 72 C0729842
Orphanet 58 ORPHA35686
UMLS 71 C0729842

Summaries for Serpiginous Choroiditis

NIH Rare Diseases : 52 Serpiginous choroiditis is a rare inflammatory eye condition that typically develops between age 30 and 70 years. Affected individuals have lesions in the eye that last from weeks to months and involve scarring of the eye tissue . Recurrence of these lesions is common in serpiginous choroiditis. Vision loss may occur in one or both eyes when the macula is involved. Treatment options involve anti-inflammatory and immune-suppressing medications.

MalaCards based summary : Serpiginous Choroiditis, also known as geographic helicoid peripapillary choroidopathy, is related to choroiditis and uveitis. The drugs Bevacizumab and Angiogenesis Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and testes.

Wikipedia : 74 Serpiginous choroiditis, also known as geographic or helicoid choroidopathy, is an uncommon chronic... more...

Related Diseases for Serpiginous Choroiditis

Diseases related to Serpiginous Choroiditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 choroiditis 11.1
2 uveitis 10.5
3 posterior uveitis 10.3
4 acute posterior multifocal placoid pigment epitheliopathy 10.3
5 sarcoidosis 1 10.3
6 herpes simplex 10.3
7 systemic lupus erythematosus 10.2
8 pars planitis 10.2
9 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.2
10 neuroretinitis 10.2
11 chorioretinal scar 10.2
12 autoimmune hepatitis 10.2
13 retinitis 10.2
14 syphilis 10.2
15 retinal disease 10.2
16 macular holes 10.2
17 vasculitis 10.2
18 chickenpox 10.2
19 crohn's disease 10.2
20 scotoma 10.2
21 temporal arteritis 10.2
22 celiac disease 1 10.2
23 inflammatory bowel disease 10.2
24 optic papillitis 10.2
25 retinal ischemia 10.2
26 retinal vein occlusion 10.2
27 central retinal vein occlusion 10.2
28 antiphospholipid syndrome 10.2
29 purpura 10.2
30 systemic scleroderma 10.2
31 intraocular lymphoma 10.2
32 raynaud phenomenon 10.2
33 retinal detachment 10.0
34 lymphoma, hodgkin, classic 10.0
35 retinitis pigmentosa 10.0
36 lymphoma, non-hodgkin, familial 10.0
37 mycobacterium tuberculosis 1 10.0
38 microvascular complications of diabetes 5 10.0
39 neutropenia 10.0
40 scleritis 10.0
41 posterior scleritis 10.0
42 hepatitis 10.0
43 retinal vascular disease 10.0
44 cervix carcinoma 10.0
45 macular retinal edema 10.0
46 dystonia 10.0
47 lupus erythematosus 10.0
48 chorioretinitis 10.0
49 iridocyclitis 10.0
50 toxoplasmosis 10.0

Graphical network of the top 20 diseases related to Serpiginous Choroiditis:



Diseases related to Serpiginous Choroiditis

Symptoms & Phenotypes for Serpiginous Choroiditis

Drugs & Therapeutics for Serpiginous Choroiditis

Drugs for Serpiginous Choroiditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bevacizumab Approved, Investigational Phase 3 216974-75-3
2 Angiogenesis Inhibitors Phase 3
3 Antineoplastic Agents, Immunological Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intravitreal Bevacizumab for the Treatment of Neovascular Membranes in Patients With Intraocular Inflammation Completed NCT00407121 Phase 3 Bevacizumab
2 Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular Neovascularization: Multicenter Collaborative Study Completed NCT00645697

Search NIH Clinical Center for Serpiginous Choroiditis

Genetic Tests for Serpiginous Choroiditis

Anatomical Context for Serpiginous Choroiditis

MalaCards organs/tissues related to Serpiginous Choroiditis:

40
Eye, Retina, Testes, Endothelial, Lung, Cervix

Publications for Serpiginous Choroiditis

Articles related to Serpiginous Choroiditis:

(show top 50) (show all 178)
# Title Authors PMID Year
1
Macular serpiginous choroiditis secondary to tuberculosis. 61
32354426 2020
2
[Placoid pigment epitheliopathy and serpiginous choroiditis]. 61
32007311 2020
3
Placoid pigment epitheliopathy and serpiginous choroiditis. 61
31932062 2020
4
VITREOUS TREPONEMAL ANTIBODY AS A SUPPLEMENTARY TEST TO SEROLOGY FOR THE CONFIRMATION OF SYPHILITIC CHORIORETINITIS. 61
29176538 2020
5
[White dot syndromes : Principles, diagnostics, and treatment]. 61
31748943 2019
6
Textural Properties of Choriocapillaris on OCTA in Healed Inflammatory Choriocapillaropathies. 61
31589754 2019
7
Choroidal neovascularisation secondary to serpiginous choroiditis: The value of OCT-angiography in diagnosis and response to therapy with aflibercept. 61
30733067 2019
8
Case Report: A Rare Variant of Macular Serpiginous Choroiditis. 61
31318798 2019
9
Cyclosporine and prednisolone combination therapy as a potential therapeutic strategy for relentless placoid chorioretinitis. 61
30984889 2019
10
Limited efficacy of adalimumab in the acute phase of serpiginous choroiditis refractory to corticosteroid and cyclosporine, a case report. 61
31014297 2019
11
Commentary: Serpiginous choroiditis-so near yet so far. 61
30777947 2019
12
Enigma of serpiginous choroiditis. 61
30777946 2019
13
SERPIGINOUS CHOROIDITIS IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. 61
28033230 2018
14
An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management. 61
30209691 2018
15
Multimodal Imaging to Monitor Recurrent Serpiginous Choroiditis. 61
29937127 2018
16
Swept-Source OCT Angiography of Serpiginous Choroiditis. 61
30148243 2018
17
Macular serpiginous choroiditis - case report. 61
30505991 2018
18
Swept-source optical coherence tomography angiography in serpiginous choroiditis. 61
28982952 2018
19
Similarities and differences between three different types of white dot syndrome and the therapeutic possibilities. 61
30505986 2018
20
Optical Coherence Tomography Features of Tuberculous Serpiginous-like Choroiditis and Serpiginous Choroiditis. 61
29866214 2018
21
Forme fruste focal choroidal excavation in a case of serpiginous choroiditis. 61
28965349 2018
22
Quantitative polymerase chain reaction analysis of serpiginous choroiditis with biopsy-proven testicular tuberculosis. 61
29380793 2018
23
Multimodal Evaluation of Patients with Acute Posterior Multifocal Placoid Pigment Epitheliopathy and Serpiginous Choroiditis. 61
28960121 2018
24
Short-term Intensive Immunosuppression: A Randomized, Three-arm Study of Intravenous Pulse Methylprednisolone and Cyclophosphamide in Macular Serpiginous Choroiditis. 61
27849419 2018
25
Treatment of Serpiginous Choroiditis with Chlorambucil: A Report of 17 Patients. 61
27754769 2018
26
The Incidence of Ocular Tuberculosis in Australia Over the Past 10 Years (2006-2015). 61
28901810 2017
27
Serpiginous Choroiditis. 61
28418567 2017
28
Treatment Results in Serpiginous Choroiditis and Multifocal Serpiginoid Choroiditis Associated with Latent Tuberculosis. 61
28405483 2017
29
Multimodal Imaging Including Optical Coherence Tomography Angiography in Serpiginous Choroiditis. 61
28281863 2017
30
Inflammatory choroidal neovascularization in Indian eyes: Etiology, clinical features, and outcomes to anti-vascular endothelial growth factor. 61
28513493 2017
31
Observation and Clinical Pattern in Patients with White Dot Syndromes: The Role of Color Photography in Monitoring Ocular Changes in Long-Term Observation. 61
28253223 2017
32
Dexamethasone intravitreal implant in serpiginous choroiditis. 61
27256717 2017
33
Multimodal Imaging of Serpiginous Choroiditis. 61
27779556 2017
34
A Rare Case of Infectious Multifocal Serpiginoid Choroiditis 61
29117661 2016
35
Preservation of macular structure and function after intravitreal aflibercept for choroidal neovascularization associated with serpiginous choroiditis. 61
26780597 2016
36
ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY FEATURES IN AREAS OF CHORIOCAPILLARIS HYPOPERFUSION. 61
27078798 2016
37
Relentless placoid chorioretinitis – A case report. 61
29653039 2016
38
Efficacy of reduced dose of intravitreal triamcinolone acetonide in a case of active serpiginous choroiditis. 61
27853021 2016
39
Paradoxical Worsening of Tubercular Serpiginous-Like Choroiditis after Initiation of Antitubercular Therapy. 61
28058156 2016
40
[A form of macular serpiginous choroiditis]. 61
26951876 2016
41
A Case of Ampiginous Choroiditis. 61
26955348 2015
42
Simultaneous Single Dexamethasone Implant and Ranibizumab Injection in a Case with Active Serpiginous Choroiditis and Choroidal Neovascular Membrane. 61
26955341 2015
43
Pulse cyclophosphamide therapy in the management of patients with macular serpiginous choroidopathy. 61
26044470 2015
44
Serpiginous choroiditis with atypical presentation treated with intravenous methyl prednisolone. 61
24117451 2015
45
[Macular serpiginous choroiditis]. 61
26327987 2015
46
Real-time and nested polymerase chain reaction in the diagnosis of multifocal serpiginoid choroiditis caused by Mycobacterium tuberculosis - a case report. 61
26530346 2014
47
Impaired circulation in the thickened choroid of a patient with serpiginous choroiditis. 61
24724811 2014
48
Serpiginous choroiditis in a referral clinic in India: visual field changes and clinical correlates. 61
24724910 2014
49
Effectiveness of adalimumab for refractory serpiginous choroiditis. 61
24304367 2014
50
Riding the wave: challenges in the management of serpiginous choroiditis. 61
25307556 2014

Variations for Serpiginous Choroiditis

Expression for Serpiginous Choroiditis

Search GEO for disease gene expression data for Serpiginous Choroiditis.

Pathways for Serpiginous Choroiditis

GO Terms for Serpiginous Choroiditis

Sources for Serpiginous Choroiditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....