SSOS
MCID: SHR107
MIFTS: 26

Short Stature-Obesity Syndrome (SSOS)

Categories: Metabolic diseases

Aliases & Classifications for Short Stature-Obesity Syndrome

MalaCards integrated aliases for Short Stature-Obesity Syndrome:

Name: Short Stature-Obesity Syndrome 56 71
Ssos 56

Characteristics:

OMIM:

56
Inheritance:
autosomal recessive


HPO:

31
short stature-obesity syndrome:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 56 269870
MedGen 41 C1849235
UMLS 71 C1849235

Summaries for Short Stature-Obesity Syndrome

MalaCards based summary : Short Stature-Obesity Syndrome, also known as ssos, is related to in situ carcinoma and ductal carcinoma in situ. The drug Mitogens has been mentioned in the context of this disorder. Affiliated tissues include brain, liver and bone marrow, and related phenotypes are microtia and short stature

More information from OMIM: 269870

Related Diseases for Short Stature-Obesity Syndrome

Graphical network of the top 20 diseases related to Short Stature-Obesity Syndrome:



Diseases related to Short Stature-Obesity Syndrome

Symptoms & Phenotypes for Short Stature-Obesity Syndrome

Human phenotypes related to Short Stature-Obesity Syndrome:

31 (show all 12)
# Description HPO Frequency HPO Source Accession
1 microtia 31 HP:0008551
2 short stature 31 HP:0004322
3 micrognathia 31 HP:0000347
4 obesity 31 HP:0001513
5 brachydactyly 31 HP:0001156
6 clinodactyly of the 5th finger 31 HP:0004209
7 prominent nasal bridge 31 HP:0000426
8 micromelia 31 HP:0002983
9 sloping forehead 31 HP:0000340
10 limb undergrowth 31 HP:0009826
11 narrow forehead 31 HP:0000341
12 narrow nose 31 HP:0000460

Symptoms via clinical synopsis from OMIM:

56
Growth:
short stature
obesity

Limbs:
brachydactyly
fifth finger clinodactyly
short limbs

H E E N T:
micrognathia
prominent nasal bridge
narrow nose
small ears
sloping, narrow forehead
more

Clinical features from OMIM:

269870

Drugs & Therapeutics for Short Stature-Obesity Syndrome

Drugs for Short Stature-Obesity Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mitogens

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective Trial Comparing the Performance Profiles of Two Non-Cross-Linked Porcine Dermal Matrices in Abdominal Wall Reconstruction Recruiting NCT02228889 Phase 4
2 A Prospective, Randomized, Evaluation of the Prevena™ Incision Management System on Closed Incisions in Obese Subjects Undergoing Cesarean Section Surgery Completed NCT01450631
3 A Prospective Randomized Trial of Biologic Mesh Versus Synthetic Mesh for the Repair of Complex Ventral Hernias Active, not recruiting NCT02451176

Search NIH Clinical Center for Short Stature-Obesity Syndrome

Genetic Tests for Short Stature-Obesity Syndrome

Anatomical Context for Short Stature-Obesity Syndrome

MalaCards organs/tissues related to Short Stature-Obesity Syndrome:

40
Brain, Liver, Bone Marrow, Bone, Cortex, Skin, Prostate

Publications for Short Stature-Obesity Syndrome

Articles related to Short Stature-Obesity Syndrome:

(show top 50) (show all 242)
# Title Authors PMID Year
1
Short stature, brachydactyly, small ears, and a pattern of minor anomalies in brother and sister born to consanguineous parents: a hitherto unreported syndrome? 56
2368813 1990
2
Evaluation of Incisional Negative Pressure Wound Therapy in the Prevention of Surgical Site Occurrences After Radical Cystectomy: A New Addition to Enhanced Recovery After Surgery Protocol. 61
31704281 2020
3
Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes. 61
32315661 2020
4
Surgical Technique and Case Series of Total Hip Arthroplasty with the Hueter Anterior Approach for Crowe Type-IV Dysplasia. 61
32530875 2020
5
Complications Following the Use of Biologic Mesh in Ileostomy Closure: A Retrospective, Comparative Study. 61
32511101 2020
6
Are elderly patients at high risk for postoperative complications after robotic ventral hernia repair? A propensity score matching analysis. 61
32091650 2020
7
Does the Impact of Joint Arthroplasty Extend Beyond the Patient? The Effect of Total Joint Arthroplasty on Patient's Significant Others. 61
32059820 2020
8
Antibacterial and antioxidant activities of sodium starch octenylsuccinate-based Pickering emulsion films incorporated with cinnamon essential oil. 61
32439447 2020
9
New codons for efficient production of unnatural proteins in a semisynthetic organism. 61
32251411 2020
10
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria. 61
32313951 2020
11
Alternative splicing of ACE2 possibly generates variants that may limit the entry of SARS-CoV-2: a potential therapeutic approach using SSOs. 61
32442315 2020
12
Low Medial Horizontal Osteotomy in Patients With Atypical Ramus Morphology Undergoing Sagittal Split Osteotomy. 61
32540322 2020
13
2'-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 β-thalassemia patient cells restoring HbA production and chain rebalance. 61
32439726 2020
14
Anthropogenic factors affecting wildlife species status outcomes: why the fixation on pesticides? 61
32418111 2020
15
What factors affect the attachment of the inferior alveolar nerve to the buccal plate following sagittal split osteotomy? 61
32245731 2020
16
Improving oxidative stability and release behavior of docosahexaenoic acid algae oil by microencapsulation. 61
32020617 2020
17
Quality Evaluation and Characterization of Specific Spoilage Organisms of Spanish Mackerel by High-Throughput Sequencing during 0 °C Cold Chain Logistics. 61
32182816 2020
18
Is It Necessary to Free the Inferior Alveolar Nerve From the Proximal Segment in the Sagittal Split Osteotomy? 61
32283076 2020
19
Human factors and ergonomics systems-based tools for understanding and addressing global problems of the twenty-first century. 61
31327300 2020
20
Characterization of the Volatiles and Quality of Hybrid Grouper and Their Relationship to Changes of Microbial Community During Storage at 4 °C. 61
32070021 2020
21
Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair. 61
31985216 2020
22
Clinical Applications and Benefits of Using Closed-incision Negative Pressure Therapy with Novel Dressing: A Review Article. 61
32190459 2020
23
Insights into the Identification of the Specific Spoilage Organisms in Chicken Meat. 61
32093245 2020
24
Preparation and Characterization of Emulsion-based Peony Seed Oil Microcapsule. 61
32115547 2020
25
Prevention of Fascial Dehiscence with Onlay Prophylactic Mesh in Emergency Laparotomy: A Randomized Clinical Trial. 61
31672681 2020
26
Seasonal monitoring of cocaine and benzoylecgonine in a subtropical coastal zone (Santos Bay, Brazil). 61
31543485 2019
27
The utility of stuttering support organization conventions for young people who stutter. 61
31634790 2019
28
Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons. 61
31841336 2019
29
Biochemical changes induced by dominant bacteria in chill-stored silver carp (Hypophthalmichthys molitrix) and GC-IMS identification of volatile organic compounds. 61
31421785 2019
30
Surgical Outcomes in Lateral Abdominal Wall Reconstruction: A Comparative Analysis of Surgical Techniques. 61
30998975 2019
31
Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides. 61
31123731 2019
32
Oncological safety of intrafascial nerve-sparing radical prostatectomy compared with conventional process: a pooled review and meta-regression analysis based on available studies. 61
31133039 2019
33
Evaluation of the lingual fracture patterns after bilateral sagittal split osteotomy according to Hunsuck/Epker modified by an additional inferior border osteotomy using a burr or ultrasonic device. 61
30579742 2019
34
Restoration of correct βIVS2-654-globin mRNA splicing and HbA production by engineered U7 snRNA in β-thalassaemia/HbE erythroid cells. 61
31113996 2019
35
Inflow and infiltration in coastal wastewater collection systems: effects of rainfall, temperature, and sea level. 61
30731027 2019
36
Sewage spills are a major source of titanium dioxide engineered (nano)-particles into the environment. 61
31853367 2019
37
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes. 61
30612734 2019
38
Outcomes of transversus abdominis release in non-elective incisional hernia repair: a retrospective review of the Americas Hernia Society Quality Collaborative (AHSQC). 61
30627813 2019
39
Changes in the microbial communities in vacuum-packaged smoked bacon during storage. 61
30297053 2019
40
What Do We Know About the Chevrel Technique in Ventral Incisional Hernia Repair? 61
31058162 2019
41
Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides. 61
30551900 2019
42
Local Gamma Activity During Non-REM Sleep in the Context of Sensory Evoked K-Complexes. 61
31680829 2019
43
Super short operations on both gene order and intergenic sizes. 61
31709002 2019
44
Evolution of Volatile Compounds and Spoilage Bacteria in Smoked Bacon during Refrigeration Using an E-Nose and GC-MS Combined with Partial Least Squares Regression. 61
30544999 2018
45
Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids. 61
30388622 2018
46
Shorter Phosphorodiamidate Morpholino Splice-Switching Oligonucleotides May Increase Exon-Skipping Efficacy in DMD. 61
30396145 2018
47
Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet. 61
30418780 2018
48
Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment. 61
30329087 2018
49
Evidence-Based Strategies for the Prehabilitation of the Abdominal Wall Reconstruction Patient. 61
30138261 2018
50
Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state. 61
29625109 2018

Variations for Short Stature-Obesity Syndrome

Expression for Short Stature-Obesity Syndrome

Search GEO for disease gene expression data for Short Stature-Obesity Syndrome.

Pathways for Short Stature-Obesity Syndrome

GO Terms for Short Stature-Obesity Syndrome

Sources for Short Stature-Obesity Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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