SSOS
MCID: SHR107
MIFTS: 26

Short Stature-Obesity Syndrome (SSOS)

Categories: Metabolic diseases

Aliases & Classifications for Short Stature-Obesity Syndrome

MalaCards integrated aliases for Short Stature-Obesity Syndrome:

Name: Short Stature-Obesity Syndrome 56 71
Ssos 56

Characteristics:

OMIM:

56
Inheritance:
autosomal recessive


HPO:

31
short stature-obesity syndrome:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 56 269870
MedGen 41 C1849235
UMLS 71 C1849235

Summaries for Short Stature-Obesity Syndrome

MalaCards based summary : Short Stature-Obesity Syndrome, also known as ssos, is related to in situ carcinoma and ductal carcinoma in situ. The drug Mitogens has been mentioned in the context of this disorder. Affiliated tissues include brain, liver and cortex, and related phenotypes are obesity and microtia

More information from OMIM: 269870

Related Diseases for Short Stature-Obesity Syndrome

Graphical network of the top 20 diseases related to Short Stature-Obesity Syndrome:



Diseases related to Short Stature-Obesity Syndrome

Symptoms & Phenotypes for Short Stature-Obesity Syndrome

Human phenotypes related to Short Stature-Obesity Syndrome:

31 (show all 12)
# Description HPO Frequency HPO Source Accession
1 obesity 31 HP:0001513
2 microtia 31 HP:0008551
3 brachydactyly 31 HP:0001156
4 short stature 31 HP:0004322
5 micrognathia 31 HP:0000347
6 sloping forehead 31 HP:0000340
7 narrow forehead 31 HP:0000341
8 micromelia 31 HP:0002983
9 prominent nasal bridge 31 HP:0000426
10 clinodactyly of the 5th finger 31 HP:0004209
11 narrow nose 31 HP:0000460
12 limb undergrowth 31 HP:0009826

Symptoms via clinical synopsis from OMIM:

56
Growth:
obesity
short stature

H E E N T:
micrognathia
prominent nasal bridge
narrow nose
small ears
sloping, narrow forehead
more
Limbs:
brachydactyly
fifth finger clinodactyly
short limbs

Clinical features from OMIM:

269870

Drugs & Therapeutics for Short Stature-Obesity Syndrome

Drugs for Short Stature-Obesity Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mitogens

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective Trial Comparing the Performance Profiles of Two Non-Cross-Linked Porcine Dermal Matrices in Abdominal Wall Reconstruction Recruiting NCT02228889 Phase 4
2 A Prospective, Randomized, Evaluation of the Prevena™ Incision Management System on Closed Incisions in Obese Subjects Undergoing Cesarean Section Surgery Completed NCT01450631
3 A Prospective Randomized Trial of Biologic Mesh Versus Synthetic Mesh for the Repair of Complex Ventral Hernias Active, not recruiting NCT02451176

Search NIH Clinical Center for Short Stature-Obesity Syndrome

Genetic Tests for Short Stature-Obesity Syndrome

Anatomical Context for Short Stature-Obesity Syndrome

MalaCards organs/tissues related to Short Stature-Obesity Syndrome:

40
Brain, Liver, Cortex, Skin, Prostate

Publications for Short Stature-Obesity Syndrome

Articles related to Short Stature-Obesity Syndrome:

(show top 50) (show all 220)
# Title Authors PMID Year
1
Short stature, brachydactyly, small ears, and a pattern of minor anomalies in brother and sister born to consanguineous parents: a hitherto unreported syndrome? 56
2368813 1990
2
Biochemical changes induced by dominant bacteria in chill-stored silver carp (Hypophthalmichthys molitrix) and GC-IMS identification of volatile organic compounds. 61
31421785 2019
3
Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons. 61
31841336 2019
4
The utility of stuttering support organization conventions for young people who stutter. 61
31634790 2019
5
Seasonal monitoring of cocaine and benzoylecgonine in a subtropical coastal zone (Santos Bay, Brazil). 61
31543485 2019
6
Evaluation of Incisional Negative Pressure Wound Therapy in the Prevention of Surgical Site Occurrences After Radical Cystectomy: A New Addition to Enhanced Recovery After Surgery Protocol. 61
31704281 2019
7
Prevention of Fascial Dehiscence with Onlay Prophylactic Mesh in Emergency Laparotomy: A Randomized Clinical Trial. 61
31672681 2019
8
Surgical Outcomes in Lateral Abdominal Wall Reconstruction: A Comparative Analysis of Surgical Techniques. 61
30998975 2019
9
Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides. 61
31123731 2019
10
Oncological safety of intrafascial nerve-sparing radical prostatectomy compared with conventional process: a pooled review and meta-regression analysis based on available studies. 61
31133039 2019
11
Evaluation of the lingual fracture patterns after bilateral sagittal split osteotomy according to Hunsuck/Epker modified by an additional inferior border osteotomy using a burr or ultrasonic device. 61
30579742 2019
12
Restoration of correct βIVS2-654-globin mRNA splicing and HbA production by engineered U7 snRNA in β-thalassaemia/HbE erythroid cells. 61
31113996 2019
13
Inflow and infiltration in coastal wastewater collection systems: effects of rainfall, temperature, and sea level. 61
30731027 2019
14
Sewage spills are a major source of titanium dioxide engineered (nano)-particles into the environment. 61
31853367 2019
15
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes. 61
30612734 2019
16
Outcomes of transversus abdominis release in non-elective incisional hernia repair: a retrospective review of the Americas Hernia Society Quality Collaborative (AHSQC). 61
30627813 2019
17
Changes in the microbial communities in vacuum-packaged smoked bacon during storage. 61
30297053 2019
18
What Do We Know About the Chevrel Technique in Ventral Incisional Hernia Repair? 61
31058162 2019
19
Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides. 61
30551900 2019
20
Super short operations on both gene order and intergenic sizes. 61
31709002 2019
21
Local Gamma Activity During Non-REM Sleep in the Context of Sensory Evoked K-Complexes. 61
31680829 2019
22
Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids. 61
30388622 2018
23
Evolution of Volatile Compounds and Spoilage Bacteria in Smoked Bacon during Refrigeration Using an E-Nose and GC-MS Combined with Partial Least Squares Regression. 61
30544999 2018
24
Shorter Phosphorodiamidate Morpholino Splice-Switching Oligonucleotides May Increase Exon-Skipping Efficacy in DMD. 61
30396145 2018
25
Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment. 61
30329087 2018
26
Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet. 61
30418780 2018
27
Evidence-Based Strategies for the Prehabilitation of the Abdominal Wall Reconstruction Patient. 61
30138261 2018
28
Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production. 61
29628304 2018
29
Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state. 61
29625109 2018
30
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo. 61
29858079 2018
31
Single-center ventral hernia repair with porcine dermis collagen implant. 61
28932941 2018
32
Multiresidue determination and predicted risk assessment of contaminants of emerging concern in marine sediments from the vicinities of submarine sewage outfalls. 61
29680552 2018
33
Regulation of Tak1 alternative splicing by splice-switching oligonucleotides. 61
29475001 2018
34
A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping. 61
29339778 2018
35
Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology. 61
29198111 2018
36
Comparison of a standardized negative pressure wound therapy protocol after midline celiotomy to primary skin closure and traditional open wound vacuum-assisted closure management. 61
29686547 2018
37
Sorting signed circular permutations by super short operations. 61
30065782 2018
38
Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet. 61
29309130 2018
39
Optimization of 2',4'-BNA/LNA-Based Oligonucleotides for Splicing Modulation In Vitro. 61
30171556 2018
40
Detection of New Quorum Sensing N-Acyl Homoserine Lactones From Aeromonas veronii. 61
30108567 2018
41
Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening. 61
29768479 2018
42
Does Fixation Method Affect Stability of Sagittal Split Osteotomy and Condylar Position? 61
28939191 2017
43
Drain Placement Does Not Increase Infectious Complications After Retromuscular Ventral Hernia Repair with Synthetic Mesh: an AHSQC Analysis. 61
28983795 2017
44
Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Data, 2006-2007. 61
29187322 2017
45
Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts. 61
28864392 2017
46
In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism. 61
28796508 2017
47
A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides. 61
28703575 2017
48
Closed-Incision Negative-Pressure Therapy in Obese Patients Undergoing Cesarean Delivery: A Randomized Controlled Trial. 61
28717587 2017
49
Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. 61
28118087 2017
50
From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides. 61
28123102 2017

Variations for Short Stature-Obesity Syndrome

Expression for Short Stature-Obesity Syndrome

Search GEO for disease gene expression data for Short Stature-Obesity Syndrome.

Pathways for Short Stature-Obesity Syndrome

GO Terms for Short Stature-Obesity Syndrome

Sources for Short Stature-Obesity Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....