SSOS
MCID: SHR107
MIFTS: 25

Short Stature-Obesity Syndrome (SSOS)

Categories: Metabolic diseases

Aliases & Classifications for Short Stature-Obesity Syndrome

MalaCards integrated aliases for Short Stature-Obesity Syndrome:

Name: Short Stature-Obesity Syndrome 57 72
Ssos 57

Characteristics:

OMIM:

57
Inheritance:
autosomal recessive


HPO:

32
short stature-obesity syndrome:
Inheritance autosomal recessive inheritance


Classifications:



External Ids:

OMIM 57 269870
MedGen 42 C1849235
UMLS 72 C1849235

Summaries for Short Stature-Obesity Syndrome

MalaCards based summary : Short Stature-Obesity Syndrome, also known as ssos, is related to ductal carcinoma in situ and in situ carcinoma. The drug Mitogens has been mentioned in the context of this disorder. Affiliated tissues include brain, liver and prostate, and related phenotypes are obesity and microtia

More information from OMIM: 269870

Related Diseases for Short Stature-Obesity Syndrome

Graphical network of the top 20 diseases related to Short Stature-Obesity Syndrome:



Diseases related to Short Stature-Obesity Syndrome

Symptoms & Phenotypes for Short Stature-Obesity Syndrome

Human phenotypes related to Short Stature-Obesity Syndrome:

32 (show all 12)
# Description HPO Frequency HPO Source Accession
1 obesity 32 HP:0001513
2 microtia 32 HP:0008551
3 short stature 32 HP:0004322
4 micrognathia 32 HP:0000347
5 narrow forehead 32 HP:0000341
6 micromelia 32 HP:0002983
7 prominent nasal bridge 32 HP:0000426
8 clinodactyly of the 5th finger 32 HP:0004209
9 brachydactyly 32 HP:0001156
10 sloping forehead 32 HP:0000340
11 narrow nose 32 HP:0000460
12 limb undergrowth 32 HP:0009826

Symptoms via clinical synopsis from OMIM:

57
Growth:
obesity
short stature

Limbs:
brachydactyly
fifth finger clinodactyly
short limbs

H E E N T:
micrognathia
prominent nasal bridge
narrow nose
small ears
sloping, narrow forehead
more

Clinical features from OMIM:

269870

Drugs & Therapeutics for Short Stature-Obesity Syndrome

Drugs for Short Stature-Obesity Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Mitogens

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Prospective Trial Comparing the Performance Profiles of Two Non-Cross-Linked Porcine Dermal Matrices in Abdominal Wall Reconstruction Recruiting NCT02228889 Phase 4
2 A Prospective, Randomized, Evaluation of the Prevena™ Incision Management System on Closed Incisions in Obese Subjects Undergoing Cesarean Section Surgery Completed NCT01450631
3 A Prospective Randomized Trial of Biologic Mesh Versus Synthetic Mesh for the Repair of Complex Ventral Hernias Active, not recruiting NCT02451176

Search NIH Clinical Center for Short Stature-Obesity Syndrome

Genetic Tests for Short Stature-Obesity Syndrome

Anatomical Context for Short Stature-Obesity Syndrome

MalaCards organs/tissues related to Short Stature-Obesity Syndrome:

41
Brain, Liver, Prostate, Skin, Cortex

Publications for Short Stature-Obesity Syndrome

Articles related to Short Stature-Obesity Syndrome:

(show top 50) (show all 211)
# Title Authors PMID Year
1
Short stature, brachydactyly, small ears, and a pattern of minor anomalies in brother and sister born to consanguineous parents: a hitherto unreported syndrome? 8
2368813 1990
2
Biochemical changes induced by dominant bacteria in chill-stored silver carp (Hypophthalmichthys molitrix) and GC-IMS identification of volatile organic compounds. 38
31421785 2019
3
Surgical Outcomes in Lateral Abdominal Wall Reconstruction: A Comparative Analysis of Surgical Techniques. 38
30998975 2019
4
Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides. 38
31123731 2019
5
Oncological safety of intrafascial nerve-sparing radical prostatectomy compared with conventional process: a pooled review and meta-regression analysis based on available studies. 38
31133039 2019
6
Restoration of correct βIVS2-654-globin mRNA splicing and HbA production by engineered U7 snRNA in β-thalassaemia/HbE erythroid cells. 38
31113996 2019
7
Evaluation of the lingual fracture patterns after bilateral sagittal split osteotomy according to Hunsuck/Epker modified by an additional inferior border osteotomy using a burr or ultrasonic device. 38
30579742 2019
8
Inflow and infiltration in coastal wastewater collection systems: effects of rainfall, temperature, and sea level. 38
30731027 2019
9
Outcomes of transversus abdominis release in non-elective incisional hernia repair: a retrospective review of the Americas Hernia Society Quality Collaborative (AHSQC). 38
30627813 2019
10
Changes in the microbial communities in vacuum-packaged smoked bacon during storage. 38
30297053 2019
11
Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes. 38
30612734 2019
12
Synthesis of 2'-O-(N-methylcarbamoylethyl) 5-methyl-2-thiouridine and its application to splice-switching oligonucleotides. 38
30551900 2019
13
What Do We Know About the Chevrel Technique in Ventral Incisional Hernia Repair? 38
31058162 2019
14
Shorter Phosphorodiamidate Morpholino Splice-Switching Oligonucleotides May Increase Exon-Skipping Efficacy in DMD. 38
30396145 2018
15
Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids. 38
30388622 2018
16
Evolution of Volatile Compounds and Spoilage Bacteria in Smoked Bacon during Refrigeration Using an E-Nose and GC-MS Combined with Partial Least Squares Regression. 38
30544999 2018
17
Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment. 38
30329087 2018
18
Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet. 38
30418780 2018
19
Evidence-Based Strategies for the Prehabilitation of the Abdominal Wall Reconstruction Patient. 38
30138261 2018
20
Generation of splice switching oligonucleotides targeting the Cockayne syndrome group B gene product in order to change the diseased cell state. 38
29625109 2018
21
Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production. 38
29628304 2018
22
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo. 38
29858079 2018
23
Single-center ventral hernia repair with porcine dermis collagen implant. 38
28932941 2018
24
Multiresidue determination and predicted risk assessment of contaminants of emerging concern in marine sediments from the vicinities of submarine sewage outfalls. 38
29680552 2018
25
Regulation of Tak1 alternative splicing by splice-switching oligonucleotides. 38
29475001 2018
26
A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping. 38
29339778 2018
27
Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology. 38
29198111 2018
28
Comparison of a standardized negative pressure wound therapy protocol after midline celiotomy to primary skin closure and traditional open wound vacuum-assisted closure management. 38
29686547 2018
29
Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet. 38
29309130 2018
30
Sorting signed circular permutations by super short operations. 38
30065782 2018
31
Detection of New Quorum Sensing N-Acyl Homoserine Lactones From Aeromonas veronii. 38
30108567 2018
32
Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening. 38
29768479 2018
33
Optimization of 2',4'-BNA/LNA-Based Oligonucleotides for Splicing Modulation In Vitro. 38
30171556 2018
34
Does Fixation Method Affect Stability of Sagittal Split Osteotomy and Condylar Position? 38
28939191 2017
35
Drain Placement Does Not Increase Infectious Complications After Retromuscular Ventral Hernia Repair with Synthetic Mesh: an AHSQC Analysis. 38
28983795 2017
36
Sanitary Sewer Overflows and Emergency Room Visits for Gastrointestinal Illness: Analysis of Massachusetts Data, 2006-2007. 38
29187322 2017
37
Amphiphilic lipopeptide significantly enhances uptake of charge-neutral splice switching morpholino oligonucleotide in spinal muscular atrophy patient-derived fibroblasts. 38
28864392 2017
38
A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides. 38
28703575 2017
39
In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism. 38
28796508 2017
40
Closed-Incision Negative-Pressure Therapy in Obese Patients Undergoing Cesarean Delivery: A Randomized Controlled Trial. 38
28717587 2017
41
Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy. 38
28118087 2017
42
From the Cover: The Minipig is a Suitable Non-Rodent Model in the Safety Assessment of Single Stranded Oligonucleotides. 38
28123102 2017
43
Rainfall effects on inflow and infiltration in wastewater treatment systems in a coastal plain region. 38
28452783 2017
44
Closed incision negative pressure therapy: international multidisciplinary consensus recommendations. 38
27170231 2017
45
Attenuated Total Reflectance Fourier transform infrared spectroscopy for determination of Long Chain Free Fatty Acid concentration in oily wastewater using the double wavenumber extrapolation technique. 38
28153294 2017
46
Preoperative Chlorhexidine Gluconate Use Can Increase Risk for Surgical Site Infections after Ventral Hernia Repair. 38
28017808 2017
47
A semisynthetic organism engineered for the stable expansion of the genetic alphabet. 38
28115716 2017
48
Short (16-mer) locked nucleic acid splice-switching oligonucleotides restore dystrophin production in Duchenne Muscular Dystrophy myotubes. 38
28742140 2017
49
Characterization of specific spoilage organisms (SSOs) in vacuum-packed ham by culture-plating techniques and MiSeq next-generation sequencing technologies. 38
27144959 2017
50
Utility of indocyanine-green fluorescent imaging during robot-assisted sphincter-saving surgery on rectal cancer patients. 38
26486376 2016

Variations for Short Stature-Obesity Syndrome

Expression for Short Stature-Obesity Syndrome

Search GEO for disease gene expression data for Short Stature-Obesity Syndrome.

Pathways for Short Stature-Obesity Syndrome

GO Terms for Short Stature-Obesity Syndrome

Sources for Short Stature-Obesity Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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