Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: SHR118
MIFTS: 28

Shrimp Allergy

Categories: Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs
Sources

Aliases & Classifications for Shrimp Allergy

About this section

MalaCards integrated aliases for Shrimp Allergy:

Name: Shrimp Allergy 12 15

Classifications:

MalaCards categories:
Anatomical: Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:0040001
Sources

Summaries for Shrimp Allergy

About this section
Disease Ontology : 12 A crustacean allergy that has allergic trigger shrimp.

MalaCards based summary : Shrimp Allergy is related to crustacean allergy and brown shrimp allergy. An important gene associated with Shrimp Allergy is IL13 (Interleukin 13), and among its related pathways/superpathways are Cardiac conduction and cGMP-PKG signaling pathway. The drugs Immunoglobulin E and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells.

Sources

Related Diseases for Shrimp Allergy

About this section

Diseases related to Shrimp Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 crustacean allergy 27.8 TPM4 TPM3 TPM2 TPM1 PEDS1 COPS7A
2 brown shrimp allergy 11.2
3 white shrimp allergy 11.2
4 food allergy 10.4
5 pemphigoid 10.3 IL13 HLA-DQB1
6 nut allergy 10.3 IL13 CCR6
7 achalasia, familial esophageal 10.3 HLA-DQB1 HLA-DQA1
8 primary adrenal insufficiency 10.3 HLA-DQB1 HLA-DQA1
9 autoimmune hepatitis type 1 10.3 HLA-DQB1 HLA-DQA1
10 focal epithelial hyperplasia 10.3 HLA-DQB1 HLA-DQA1
11 latex allergy 10.3 IL13 HLA-DQB1
12 podoconiosis 10.2 HLA-DQB1 HLA-DQA1
13 mikulicz disease 10.2 IL13 CCR6
14 oligoarticular juvenile idiopathic arthritis 10.2 HLA-DQB1 HLA-DQA1
15 breast implant-associated anaplastic large cell lymphoma 10.2 IL13 CCR6
16 dacryoadenitis 10.2 IL13 CCR6
17 congenital toxoplasmosis 10.2 HLA-DQB1 HLA-DQA1
18 fungal meningitis 10.2 IL13 CCR6
19 chronic conjunctivitis 10.2 IL13 CCR6
20 intestinal schistosomiasis 10.2 IL13 CCR6
21 chronic rhinitis 10.2 IL13 COPS7A
22 type 1 diabetes mellitus 2 10.2 HLA-DQB1 HLA-DQA1
23 wheat allergy 10.2 HLA-DQB1 COPS7A
24 childhood type dermatomyositis 10.2 HLA-DQA1 CCR6
25 cervical dystonia 10.2 HLA-DQB1 HLA-DQA1
26 sialadenitis 10.2 HLA-DQB1 CCR6
27 autoimmune gastritis 10.2 HLA-DQB1 CCR6
28 adrenal cortical hypofunction 10.2 HLA-DQA1 CCR6
29 cryptococcosis 10.2 IL13 CCR6
30 histoplasmosis 10.2 HLA-DQA1 CCR6
31 immunoglobulin alpha deficiency 10.2 HLA-DQB1 CCR6
32 endometritis 10.2 HLA-DQB1 HLA-DQA1
33 urticaria 10.2
34 esophagitis, eosinophilic, 1 10.2 IL13 CCR6
35 conjunctival disease 10.2 IL13 CCR6
36 splenic disease 10.2 IL13 CCR6
37 guillain-barre syndrome 10.2 HLA-DQB1 HLA-DQA1
38 onchocerciasis 10.2 IL13 HLA-DQA1
39 posterior uveitis 10.2 IL13 CCR6
40 panuveitis 10.2 HLA-DQB1 CCR6
41 dermatitis herpetiformis 10.1 HLA-DQB1 HLA-DQA1
42 opportunistic mycosis 10.1 IL13 CCR6
43 paranasal sinus disease 10.1 IL13 CCR6
44 rheumatic fever 10.1 HLA-DQB1 HLA-DQA1
45 pelvic inflammatory disease 10.1 IL13 HLA-DQB1 HLA-DQA1
46 rheumatic heart disease 10.1 HLA-DQB1 HLA-DQA1
47 leishmaniasis 10.1 IL13 HLA-DQB1 HLA-DQA1
48 autoimmune disease of endocrine system 10.1 HLA-DQA1 CCR6
49 anisakiasis 10.1 TPM4 TPM2
50 fungal infectious disease 10.1 IL13 CCR6

Graphical network of the top 20 diseases related to Shrimp Allergy:



Diseases related to Shrimp Allergy
Sources

Symptoms & Phenotypes for Shrimp Allergy

About this section
Sources

Drugs & Therapeutics for Shrimp Allergy

About this section

Drugs for Shrimp Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunoglobulin E
2 Immunoglobulins
3 Immunoglobulins, Intravenous
4 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis Completed NCT01619605
2 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813
3 Immunological Response After Shrimp Oral Immunotherapy Treatment: A Pilot Study Recruiting NCT04552522

Search NIH Clinical Center for Shrimp Allergy

Sources

Genetic Tests for Shrimp Allergy

About this section
Sources

Anatomical Context for Shrimp Allergy

About this section

MalaCards organs/tissues related to Shrimp Allergy:

40
Skin, T Cells
Sources

Publications for Shrimp Allergy

About this section

Articles related to Shrimp Allergy:

(show top 50) (show all 74)
# Title Authors PMID Year
1
Cell-Based Functional IgE Assays Are Superior to Conventional Allergy Tests for Shrimp Allergy Diagnosis. 61
32931950 2021
2
Association of HLA-DQ and IL13 gene variants with challenge-proven shrimp allergy in West Bengal, India. 61
33175217 2020
3
House dust mite allergy and shrimp allergy: a complex interaction. 61
31594291 2020
4
T cell epitope of arginine kinase with CpG co-encapsulated nanoparticles attenuates a shrimp allergen-induced Th2-bias food allergy. 61
31795812 2020
5
Pen a 1-specific IgE does not improve the accuracy of a shrimp allergy diagnosis among Japanese children due to cross-reactivity with Der p 10. 61
31685384 2020
6
In vivo characterization of histological and immunological response of allergic protein of Metapenaeus dobsonii using an adjuvant free BALB/c mice model. 61
31809765 2020
7
Identification of allergic proteins of Flower tail shrimp (Metapenaeus dobsonii). 61
31749489 2019
8
Glycation by saccharides of different molecular sizes affected the allergenicity of shrimp tropomyosin via epitope loss and the generation of advanced glycation end products. 61
31580362 2019
9
Modulating Shrimp Tropomyosin-Mediated Allergy: Hypoallergen DNA Vaccines Induce Regulatory T Cells to Reduce Hypersensitivity in Mouse Model. 61
31546958 2019
10
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults. 61
31247376 2019
11
Natural resolution of non-anaphylactic shrimp allergy in patients diagnosed 10 years earlier by oral food challenge. 61
31012598 2019
12
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy. 61
30597474 2019
13
Improved diagnostic clarity in shrimp allergic non-dust-mite sensitized patients. 61
30153888 2018
14
Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy. 61
29655746 2018
15
Oral food challenges: result of a 16-year experience at a major teaching hospital in Thailand. 61
29732297 2018
16
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. 61
29348432 2018
17
Shrimp allergy: beyond avoidance diet. 61
29249132 2017
18
Is mealworm or shrimp allergy indicative for food allergy to insects? 61
28500661 2017
19
Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens. 61
28039304 2017
20
[Effect of High Hydrostatic Pressure Combined with Temperature on the Antigenicity and Conformation of Tropomyosin Purified from Shrimp]. 61
30291771 2017
21
Shrimp Allergy: Analysis of Commercially Available Extracts for In Vivo Diagnosis. 61
27959286 2017
22
Mite-Induced Asthma and IgE Levels to Shrimp, Mite, Tropomyosin, Arginine Kinase, and Der p 10 Are the Most Relevant Risk Factors for Challenge-Proven Shrimp Allergy. 61
29169170 2017
23
Low-Dose Allergen-Specific Immunotherapy Induces Tolerance in a Murine Model of Shrimp Allergy. 61
29065408 2017
24
Cloning and characterization of recombinant tropomyosin of giant freshwater shrimp M. rosenbergii to determine major allergens causing allergic reactions among shrimp-allergic children. 61
27001653 2016
25
T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. 61
26610061 2016
26
Shrimp allergy: Gastrointestinal symptoms commonly occur in the absence of IgE sensitization. 61
26563673 2016
27
Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin? 61
26739402 2016
28
Risk factors in pediatric shrimp allergy. 61
26108073 2015
29
Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity. 61
25769902 2015
30
Digestibility and Immunoreactivity of Shrimp Extracts Using an In Vitro Digestibility Model with Pepsin and Pancreatin. 61
26077284 2015
31
Stability and potency of raw and boiled shrimp extracts for skin prick test. 61
26141035 2015
32
Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore. 61
25257922 2015
33
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity. 61
26112225 2015
34
Relationship between the risk for a shrimp allergy and freshness or cooking. 61
25966963 2015
35
Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin. 61
25224947 2014
36
New shrimp IgE-binding proteins involved in mite-seafood cross-reactivity. 61
24978201 2014
37
Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis). 61
24996992 2014
38
The utility of serum tryptase in the diagnosis of food-induced anaphylaxis. 61
24991453 2014
39
Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. 61
25365343 2014
40
[Identification of 70 kDa shrimp protein as a possible new allergen for shrimp allergy]. 61
24335423 2013
41
Structural and immunological characterization of recombinant Pan b 1, a major allergen of northern shrimp, Pandalus borealis. 61
23075760 2013
42
[Mass spectrometry identification and immune cross-reactivity of a minor shrimp allergen-sarcoplasmic calcium binding protein from Litopenaeus vannamei]. 61
22863586 2012
43
Is epitope recognition of shrimp allergens useful to predict clinical reactivity? 61
22192087 2012
44
Shrimp allergy in Italian adults: a multicenter study showing a high prevalence of sensitivity to novel high molecular weight allergens. 61
21894023 2012
45
Safety of chitosan bandages in shellfish allergic patients. 61
22128651 2011
46
Improvement of shrimp allergy after sublingual immunotherapy for house dust mites: a case report. 61
22145252 2011
47
Tropomyosin IgE-positive results are a good predictor of shrimp allergy. 61
21651567 2011
48
Immunoglobulin E-mediated food allergies among adults with allergic rhinitis. 61
20723775 2010
49
Greater epitope recognition of shrimp allergens by children than by adults suggests that shrimp sensitization decreases with age. 61
20471069 2010
50
[Identification, isolation, purification of allergens in shrimp and allergic analysis for the main allergens]. 61
20423651 2010
Sources

Variations for Shrimp Allergy

About this section
Sources

Expression for Shrimp Allergy

About this section
Search GEO for disease gene expression data for Shrimp Allergy.
Sources

Pathways for Shrimp Allergy

About this section

Pathways related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Cardiac conduction 65
Show member pathways
 12.4 TPM4 TPM3 TPM2 TPM1
2
cGMP-PKG signaling pathway 36
Show member pathways
 12.12 TPM4 TPM3 TPM2 TPM1
3
Dilated cardiomyopathy 36
Show member pathways
 11.83 TPM4 TPM3 TPM2 TPM1
4
Cardiac muscle contraction 36
11.4 TPM4 TPM3 TPM2 TPM1
5
G-protein signaling N-RAS regulation pathway 23
Show member pathways
 11.36 HLA-DQB1 HLA-DQA1
6
Striated Muscle Contraction 65 1
11.11 TPM4 TPM3 TPM2 TPM1
7
Smooth Muscle Contraction 65
10.48 TPM4 TPM3 TPM2 TPM1
Sources

GO Terms for Shrimp Allergy

About this section

Cellular components related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin cytoskeleton GO:0015629 9.46 TPM4 TPM3 TPM2 TPM1
2 transport vesicle membrane GO:0030658 9.43 HLA-DQB1 HLA-DQA1
3 stress fiber GO:0001725 9.43 TPM4 TPM3 TPM1
4 clathrin-coated endocytic vesicle membrane GO:0030669 9.4 HLA-DQB1 HLA-DQA1
5 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 9.37 HLA-DQB1 HLA-DQA1
6 MHC class II protein complex GO:0042613 9.32 HLA-DQB1 HLA-DQA1
7 actin filament GO:0005884 9.26 TPM4 TPM3 TPM2 TPM1
8 muscle thin filament tropomyosin GO:0005862 8.92 TPM4 TPM3 TPM2 TPM1

Biological processes related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.62 IL13 HLA-DQB1 HLA-DQA1 CCR6
2 actin filament organization GO:0007015 9.46 TPM4 TPM3 TPM2 TPM1
3 antigen processing and presentation GO:0019882 9.37 HLA-DQB1 HLA-DQA1
4 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 9.26 HLA-DQB1 HLA-DQA1
5 muscle contraction GO:0006936 9.26 TPM4 TPM3 TPM2 TPM1
6 muscle filament sliding GO:0030049 8.92 TPM4 TPM3 TPM2 TPM1

Molecular functions related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin binding GO:0003779 9.56 TPM4 TPM3 TPM2 TPM1
2 peptide antigen binding GO:0042605 9.32 HLA-DQB1 HLA-DQA1
3 actin filament binding GO:0051015 9.26 TPM4 TPM3 TPM2 TPM1
4 MHC class II receptor activity GO:0032395 9.16 HLA-DQB1 HLA-DQA1
5 structural constituent of muscle GO:0008307 8.8 TPM4 TPM2 TPM1
Sources

Sources for Shrimp Allergy

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....