MCID: SHR118
MIFTS: 29

Shrimp Allergy

Categories: Immune diseases

Aliases & Classifications for Shrimp Allergy

MalaCards integrated aliases for Shrimp Allergy:

Name: Shrimp Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040001

Summaries for Shrimp Allergy

Disease Ontology : 12 A crustacean allergy that has allergic trigger shrimp.

MalaCards based summary : Shrimp Allergy is related to crustacean allergy and brown shrimp allergy. An important gene associated with Shrimp Allergy is TPM4 (Tropomyosin 4), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Cardiac conduction. The drugs Chitosan and Coagulants have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and t cells, and related phenotype is Decreased cell migration.

Related Diseases for Shrimp Allergy

Diseases related to Shrimp Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 crustacean allergy 26.0 TPSD1 TNFRSF10C TMEM189 SDF4 LGALS3 HLA-DQA2
2 brown shrimp allergy 12.4
3 white shrimp allergy 12.4
4 food allergy 10.5
5 childhood-onset nemaline myopathy 10.4 TPM3 TPM2
6 cap myopathy 10.4 TPM3 TPM2
7 congenital structural myopathy 10.3 TPM3 TPM2
8 fetal adenoma 10.3 LGALS3 ACTB
9 urticaria 10.2
10 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.2 TPM3 TPM2
11 immunoglobulin e concentration, serum 10.0
12 dermatitis, atopic 10.0
13 angioedema 10.0
14 dermatitis 10.0
15 mesenchymal cell neoplasm 10.0 TPM4 TPM3
16 fish allergy 10.0 TMEM189 LGALS3

Graphical network of the top 20 diseases related to Shrimp Allergy:



Diseases related to Shrimp Allergy

Symptoms & Phenotypes for Shrimp Allergy

GenomeRNAi Phenotypes related to Shrimp Allergy according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.92 ACTB MAPK14 TPM1 TPM4

Drugs & Therapeutics for Shrimp Allergy

Drugs for Shrimp Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chitosan Experimental 9012-76-4 71853
2 Coagulants
3 Lipid Regulating Agents
4 Hemostatics
5 Chelating Agents
6 Hypolipidemic Agents
7 Antimetabolites
8 Anticholesteremic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Randomized Double-Blind Placebo-Controlled Crab Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques in NTU Campus Unknown status NCT02208414
2 Safety of Chitosan as Wine Fining Agent in Shrimp Allergic Patients Unknown status NCT02151279
3 The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis Completed NCT01619605
4 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813

Search NIH Clinical Center for Shrimp Allergy

Genetic Tests for Shrimp Allergy

Anatomical Context for Shrimp Allergy

MalaCards organs/tissues related to Shrimp Allergy:

41
Skin, Testes, T Cells

Publications for Shrimp Allergy

Articles related to Shrimp Allergy:

(show top 50) (show all 65)
# Title Authors PMID Year
1
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults. 38
31247376 2019
2
Natural resolution of non-anaphylactic shrimp allergy in patients diagnosed 10 years earlier by oral food challenge. 38
31012598 2019
3
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy. 38
30597474 2019
4
Improved diagnostic clarity in shrimp allergic non-dust-mite sensitized patients. 38
30153888 2018
5
Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy. 38
29655746 2018
6
Oral food challenges: result of a 16-year experience at a major teaching hospital in Thailand. 38
29732297 2018
7
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. 38
29348432 2018
8
Shrimp allergy: beyond avoidance diet. 38
29249132 2017
9
Is mealworm or shrimp allergy indicative for food allergy to insects? 38
28500661 2017
10
[Effect of High Hydrostatic Pressure Combined with Temperature on the Antigenicity and Conformation of Tropomyosin Purified from Shrimp]. 38
30291771 2017
11
Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens. 38
28039304 2017
12
Shrimp Allergy: Analysis of Commercially Available Extracts for In Vivo Diagnosis. 38
27959286 2017
13
Low-Dose Allergen-Specific Immunotherapy Induces Tolerance in a Murine Model of Shrimp Allergy. 38
29065408 2017
14
Mite-Induced Asthma and IgE Levels to Shrimp, Mite, Tropomyosin, Arginine Kinase, and Der p 10 Are the Most Relevant Risk Factors for Challenge-Proven Shrimp Allergy. 38
29169170 2017
15
Cloning and characterization of recombinant tropomyosin of giant freshwater shrimp M. rosenbergii to determine major allergens causing allergic reactions among shrimp-allergic children. 38
27001653 2016
16
Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin? 38
26739402 2016
17
T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. 38
26610061 2016
18
Shrimp allergy: Gastrointestinal symptoms commonly occur in the absence of IgE sensitization. 38
26563673 2016
19
Risk factors in pediatric shrimp allergy. 38
26108073 2015
20
Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity. 38
25769902 2015
21
Digestibility and Immunoreactivity of Shrimp Extracts Using an In Vitro Digestibility Model with Pepsin and Pancreatin. 38
26077284 2015
22
Stability and potency of raw and boiled shrimp extracts for skin prick test. 38
26141035 2015
23
Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore. 38
25257922 2015
24
Relationship between the risk for a shrimp allergy and freshness or cooking. 38
25966963 2015
25
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity. 38
26112225 2015
26
Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin. 38
25224947 2014
27
New shrimp IgE-binding proteins involved in mite-seafood cross-reactivity. 38
24978201 2014
28
Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis). 38
24996992 2014
29
The utility of serum tryptase in the diagnosis of food-induced anaphylaxis. 38
24991453 2014
30
Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. 38
25365343 2014
31
[Identification of 70 kDa shrimp protein as a possible new allergen for shrimp allergy]. 38
24335423 2013
32
Structural and immunological characterization of recombinant Pan b 1, a major allergen of northern shrimp, Pandalus borealis. 38
23075760 2013
33
[Mass spectrometry identification and immune cross-reactivity of a minor shrimp allergen-sarcoplasmic calcium binding protein from Litopenaeus vannamei]. 38
22863586 2012
34
Is epitope recognition of shrimp allergens useful to predict clinical reactivity? 38
22192087 2012
35
Shrimp allergy in Italian adults: a multicenter study showing a high prevalence of sensitivity to novel high molecular weight allergens. 38
21894023 2012
36
Tropomyosin IgE-positive results are a good predictor of shrimp allergy. 38
21651567 2011
37
Improvement of shrimp allergy after sublingual immunotherapy for house dust mites: a case report. 38
22145252 2011
38
Safety of chitosan bandages in shellfish allergic patients. 38
22128651 2011
39
Immunoglobulin E-mediated food allergies among adults with allergic rhinitis. 38
20723775 2010
40
Greater epitope recognition of shrimp allergens by children than by adults suggests that shrimp sensitization decreases with age. 38
20471069 2010
41
[Identification, isolation, purification of allergens in shrimp and allergic analysis for the main allergens]. 38
20423651 2010
42
Measurement of IgE antibodies to shrimp tropomyosin is superior to skin prick testing with commercial extract and measurement of IgE to shrimp for predicting clinically relevant allergic reactions after shrimp ingestion. 38
20226506 2010
43
Determination of storage conditions for shrimp extracts: analysis of specific IgE-allergen profiles. 38
20527516 2010
44
Detection of a novel 20 kDa shrimp allergen showing cross-reactivity to house dust mites. 38
20355361 2010
45
Tropomyosin or not tropomyosin, what is the relevant allergen in house dust mite and snail cross allergies? 38
20355359 2010
46
Effects of boiling on the IgE-binding properties of tropomyosin of shrimp (Litopenaeus vannamei). 38
20492208 2010
47
Shellfish allergy in children. 38
19674349 2009
48
Myosin light chain is a novel shrimp allergen, Lit v 3. 38
18760458 2008
49
Specific allergy to Penaeus monodon (seawater shrimp) or Macrobrachium rosenbergii (freshwater shrimp) in shrimp-allergic children. 38
18498545 2008
50
Induction of shrimp tropomyosin-specific hypersensitivity in mice. 38
18617750 2008

Variations for Shrimp Allergy

Expression for Shrimp Allergy

Search GEO for disease gene expression data for Shrimp Allergy.

Pathways for Shrimp Allergy

GO Terms for Shrimp Allergy

Cellular components related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.85 TPM4 TPM3 TPM2 TPM1 GAPDH ACTB
2 actin cytoskeleton GO:0015629 9.56 TPM3 TPM2 TPM1 ACTB
3 stress fiber GO:0001725 9.33 TPM4 TPM3 TPM1
4 bleb GO:0032059 9.32 TPM1 SDF4
5 actin filament GO:0005884 9.26 TPM4 TPM3 TPM2 TPM1
6 muscle thin filament tropomyosin GO:0005862 8.92 TPM4 TPM3 TPM2 TPM1

Biological processes related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle contraction GO:0006936 9.46 TPM4 TPM3 TPM2 TPM1
2 actin filament organization GO:0007015 9.26 TPM4 TPM3 TPM2 TPM1
3 muscle filament sliding GO:0030049 8.92 TPM4 TPM3 TPM2 TPM1

Molecular functions related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.63 TPM4 TPM2 TPM1 SDF4 GAPDH ACTB
2 actin binding GO:0003779 9.56 TPM4 TPM3 TPM2 TPM1
3 actin filament binding GO:0051015 9.26 TPM4 TPM3 TPM2 TPM1
4 structural constituent of muscle GO:0008307 8.8 TPM4 TPM2 TPM1

Sources for Shrimp Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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