MCID: SHR118
MIFTS: 28

Shrimp Allergy

Categories: Immune diseases

Aliases & Classifications for Shrimp Allergy

MalaCards integrated aliases for Shrimp Allergy:

Name: Shrimp Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040001

Summaries for Shrimp Allergy

Disease Ontology : 12 A crustacean allergy that has allergic trigger shrimp.

MalaCards based summary : Shrimp Allergy is related to crustacean allergy and brown shrimp allergy. An important gene associated with Shrimp Allergy is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways are Cardiac conduction and cGMP-PKG signaling pathway. The drugs Chitosan and Hemostatics have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and testes.

Related Diseases for Shrimp Allergy

Diseases related to Shrimp Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
# Related Disease Score Top Affiliating Genes
1 crustacean allergy 26.2 TPSD1 TPM4 TPM3 TPM2 TPM1 TNFRSF10C
2 brown shrimp allergy 12.4
3 white shrimp allergy 12.4
4 food allergy 10.5
5 anisakiasis 10.2 TPM4 TPM2
6 urticaria 10.2
7 epithelioid inflammatory myofibroblastic sarcoma 10.2 TPM4 TPM3
8 childhood-onset nemaline myopathy 10.2 TPM3 TPM2
9 cap myopathy 10.1 TPM3 TPM2
10 dermatographia 10.1 PEDS1 CCR6
11 pthirus pubis infestation 10.1 TPM4 TPM2
12 nut allergy 10.1 PEDS1 CCR6
13 lice infestation 10.1 TPM4 TPM2
14 wheat allergy 10.1 PEDS1 COPS7A
15 myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency 10.1 TPM4 TPM2
16 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.1 TPM3 TPM2
17 parasitic ectoparasitic infectious disease 10.1 TPM4 TPM2
18 immunoglobulin e concentration, serum 10.0
19 dermatitis, atopic 10.0
20 angioedema 10.0
21 dermatitis 10.0
22 ascaris lumbricoides infection 10.0 TPM4 TPM2 COPS7A
23 egg allergy 10.0 PEDS1 COPS7A CCR6
24 mesenchymal cell neoplasm 10.0 TPM4 TPM3
25 legume allergy 10.0 PEDS1 COPS7A CCR6
26 fruit allergy 10.0 PEDS1 COPS7A CCR6
27 nasal cavity disease 10.0 PEDS1 COPS7A CCR6
28 myopathy, centronuclear, 2 9.9 TPM4 TPM3 TPM2
29 peanut allergy 9.9 PEDS1 CCR6
30 congenital fiber-type disproportion 9.9 TPM4 TPM3 TPM2
31 myopathy, centronuclear, 1 9.9 TPM4 TPM3 TPM2
32 arthrogryposis, distal, type 1a 9.9 TPM4 TPM3 TPM2
33 conjunctival disease 9.8 PEDS1 CCR6
34 nose disease 9.7 PEDS1 CCR6
35 crab allergy 9.7 TPM4 TPM3 TPM2 TPM1
36 congenital structural myopathy 9.7 TPM4 TPM3 TPM2 TPM1
37 hypertrophic cardiomyopathy 9.6 TPM4 TPM3 TPM2 TPM1
38 fish allergy 9.5 TPM4 TPM2 PEDS1 IVNS1ABP
39 snail allergy 9.5 TPM4 TPM3 TPM2 TPM1 COPS7A
40 melon allergy 9.5 TPM4 TPM3 TPM2 TPM1 COPS7A

Graphical network of the top 20 diseases related to Shrimp Allergy:



Diseases related to Shrimp Allergy

Symptoms & Phenotypes for Shrimp Allergy

Drugs & Therapeutics for Shrimp Allergy

Drugs for Shrimp Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chitosan Experimental 9012-76-4 71853
2 Hemostatics
3 Hypolipidemic Agents
4 Chelating Agents
5 Lipid Regulating Agents
6 Anticholesteremic Agents
7 Coagulants
8 Antimetabolites

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 T Cell Reagent Research for Monitoring T Cells in Food Allergy (MOTIF) Phase 2 Study Using Food Allergen Oral Immunotherapy for Shrimp or Cashew Allergies Recruiting NCT03504774 Phase 2 Cashew or Shrimp Oral Immunotherapy
2 A Randomized Double-Blind Placebo-Controlled Crab Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques in NTU Campus Unknown status NCT02208414
3 Safety of Chitosan as Wine Fining Agent in Shrimp Allergic Patients Unknown status NCT02151279
4 The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis Completed NCT01619605
5 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813

Search NIH Clinical Center for Shrimp Allergy

Genetic Tests for Shrimp Allergy

Anatomical Context for Shrimp Allergy

MalaCards organs/tissues related to Shrimp Allergy:

40
T Cells, Skin, Testes

Publications for Shrimp Allergy

Articles related to Shrimp Allergy:

(show top 50) (show all 72)
# Title Authors PMID Year
1
Pen a 1-specific IgE does not improve the accuracy of a shrimp allergy diagnosis among Japanese children due to cross-reactivity with Der p 10. 61
31685384 2020
2
T cell epitope of arginine kinase with CpG co-encapsulated nanoparticles attenuates a shrimp allergen-induced Th2-bias food allergy. 61
31795812 2020
3
In vivo characterization of histological and immunological response of allergic protein of Metapenaeus dobsonii using an adjuvant free BALB/c mice model. 61
31809765 2020
4
Identification of allergic proteins of Flower tail shrimp (Metapenaeus dobsonii). 61
31749489 2019
5
Glycation by saccharides of different molecular sizes affected the allergenicity of shrimp tropomyosin via epitope loss and the generation of advanced glycation end products. 61
31580362 2019
6
House dust mite allergy and shrimp allergy: a complex interaction. 61
31594291 2019
7
Modulating Shrimp Tropomyosin-Mediated Allergy: Hypoallergen DNA Vaccines Induce Regulatory T Cells to Reduce Hypersensitivity in Mouse Model. 61
31546958 2019
8
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults. 61
31247376 2019
9
Natural resolution of non-anaphylactic shrimp allergy in patients diagnosed 10 years earlier by oral food challenge. 61
31012598 2019
10
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy. 61
30597474 2019
11
Improved diagnostic clarity in shrimp allergic non-dust-mite sensitized patients. 61
30153888 2018
12
Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy. 61
29655746 2018
13
Oral food challenges: result of a 16-year experience at a major teaching hospital in Thailand. 61
29732297 2018
14
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. 61
29348432 2018
15
Shrimp allergy: beyond avoidance diet. 61
29249132 2017
16
Is mealworm or shrimp allergy indicative for food allergy to insects? 61
28500661 2017
17
[Effect of High Hydrostatic Pressure Combined with Temperature on the Antigenicity and Conformation of Tropomyosin Purified from Shrimp]. 61
30291771 2017
18
Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens. 61
28039304 2017
19
Mite-Induced Asthma and IgE Levels to Shrimp, Mite, Tropomyosin, Arginine Kinase, and Der p 10 Are the Most Relevant Risk Factors for Challenge-Proven Shrimp Allergy. 61
29169170 2017
20
Low-Dose Allergen-Specific Immunotherapy Induces Tolerance in a Murine Model of Shrimp Allergy. 61
29065408 2017
21
Shrimp Allergy: Analysis of Commercially Available Extracts for In Vivo Diagnosis. 61
27959286 2017
22
Cloning and characterization of recombinant tropomyosin of giant freshwater shrimp M. rosenbergii to determine major allergens causing allergic reactions among shrimp-allergic children. 61
27001653 2016
23
Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin? 61
26739402 2016
24
T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. 61
26610061 2016
25
Shrimp allergy: Gastrointestinal symptoms commonly occur in the absence of IgE sensitization. 61
26563673 2016
26
Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity. 61
25769902 2015
27
Risk factors in pediatric shrimp allergy. 61
26108073 2015
28
Digestibility and Immunoreactivity of Shrimp Extracts Using an In Vitro Digestibility Model with Pepsin and Pancreatin. 61
26077284 2015
29
Stability and potency of raw and boiled shrimp extracts for skin prick test. 61
26141035 2015
30
Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore. 61
25257922 2015
31
Relationship between the risk for a shrimp allergy and freshness or cooking. 61
25966963 2015
32
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity. 61
26112225 2015
33
Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis). 61
24996992 2014
34
New shrimp IgE-binding proteins involved in mite-seafood cross-reactivity. 61
24978201 2014
35
Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin. 61
25224947 2014
36
The utility of serum tryptase in the diagnosis of food-induced anaphylaxis. 61
24991453 2014
37
Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. 61
25365343 2014
38
[Identification of 70 kDa shrimp protein as a possible new allergen for shrimp allergy]. 61
24335423 2013
39
Structural and immunological characterization of recombinant Pan b 1, a major allergen of northern shrimp, Pandalus borealis. 61
23075760 2013
40
[Mass spectrometry identification and immune cross-reactivity of a minor shrimp allergen-sarcoplasmic calcium binding protein from Litopenaeus vannamei]. 61
22863586 2012
41
Is epitope recognition of shrimp allergens useful to predict clinical reactivity? 61
22192087 2012
42
Shrimp allergy in Italian adults: a multicenter study showing a high prevalence of sensitivity to novel high molecular weight allergens. 61
21894023 2012
43
Tropomyosin IgE-positive results are a good predictor of shrimp allergy. 61
21651567 2011
44
Improvement of shrimp allergy after sublingual immunotherapy for house dust mites: a case report. 61
22145252 2011
45
Safety of chitosan bandages in shellfish allergic patients. 61
22128651 2011
46
Immunoglobulin E-mediated food allergies among adults with allergic rhinitis. 61
20723775 2010
47
Greater epitope recognition of shrimp allergens by children than by adults suggests that shrimp sensitization decreases with age. 61
20471069 2010
48
[Identification, isolation, purification of allergens in shrimp and allergic analysis for the main allergens]. 61
20423651 2010
49
Measurement of IgE antibodies to shrimp tropomyosin is superior to skin prick testing with commercial extract and measurement of IgE to shrimp for predicting clinically relevant allergic reactions after shrimp ingestion. 61
20226506 2010
50
Determination of storage conditions for shrimp extracts: analysis of specific IgE-allergen profiles. 61
20527516 2010

Variations for Shrimp Allergy

Expression for Shrimp Allergy

Search GEO for disease gene expression data for Shrimp Allergy.

GO Terms for Shrimp Allergy

Cellular components related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.72 TPM4 TPM3 TPM2 TPM1 IVNS1ABP
2 actin cytoskeleton GO:0015629 9.54 TPM3 TPM2 TPM1
3 stress fiber GO:0001725 9.33 TPM4 TPM3 TPM1
4 bleb GO:0032059 9.26 TPM1 SDF4
5 actin filament GO:0005884 9.26 TPM4 TPM3 TPM2 TPM1
6 muscle thin filament tropomyosin GO:0005862 8.92 TPM4 TPM3 TPM2 TPM1

Biological processes related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin filament organization GO:0007015 9.46 TPM4 TPM3 TPM2 TPM1
2 muscle contraction GO:0006936 9.26 TPM4 TPM3 TPM2 TPM1
3 muscle filament sliding GO:0030049 8.92 TPM4 TPM3 TPM2 TPM1

Molecular functions related to Shrimp Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin binding GO:0003779 9.46 TPM4 TPM3 TPM2 TPM1
2 protein heterodimerization activity GO:0046982 9.43 TPM4 TPM2 TPM1
3 actin filament binding GO:0051015 9.26 TPM4 TPM3 TPM2 TPM1
4 structural constituent of muscle GO:0008307 8.8 TPM4 TPM2 TPM1

Sources for Shrimp Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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