MCID: SHR118
MIFTS: 27

Shrimp Allergy

Categories: Immune diseases

Aliases & Classifications for Shrimp Allergy

MalaCards integrated aliases for Shrimp Allergy:

Name: Shrimp Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0040001

Summaries for Shrimp Allergy

Disease Ontology : 12 A crustacean allergy that has allergic trigger shrimp.

MalaCards based summary : Shrimp Allergy is related to crustacean allergy and brown shrimp allergy. An important gene associated with Shrimp Allergy is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways are Cardiac conduction and cGMP-PKG signaling pathway. The drugs Immunologic Factors and Chitosan have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and testes.

Related Diseases for Shrimp Allergy

Diseases related to Shrimp Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 36, show less)
# Related Disease Score Top Affiliating Genes
1 crustacean allergy 25.9 TPSD1 TPM4 TPM3 TPM2 TPM1 TNFRSF10C
2 brown shrimp allergy 12.4
3 white shrimp allergy 12.4
4 food allergy 10.5
5 anisakiasis 10.2 TPM4 TPM2
6 urticaria 10.2
7 ascaris lumbricoides infection 10.2 TPM4 TPM2
8 parasitic ectoparasitic infectious disease 10.1 TPM4 TPM2
9 childhood-onset nemaline myopathy 10.1 TPM3 TPM2
10 nemaline myopathy 10.1 TPM3 TPM2
11 cap myopathy 10.1 TPM3 TPM2
12 fruit allergy 10.1 TMEM189 COPS7A
13 nut allergy 10.1 TMEM189 CCR6
14 wheat allergy 10.1 TMEM189 COPS7A
15 mesenchymal cell neoplasm 10.1 TPM4 TPM3
16 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.1 TPM3 TPM2
17 peanut allergy 10.0 TMEM189 CCR6
18 immunoglobulin e concentration, serum 10.0
19 dermatitis, atopic 10.0
20 angioedema 10.0
21 dermatitis 10.0
22 conjunctival disease 10.0 TMEM189 CCR6
23 nasal cavity disease 10.0 TMEM189 CCR6
24 nose disease 10.0 TMEM189 CCR6
25 inflammatory myofibroblastic tumor 9.9 TPM4 TPM3
26 egg allergy 9.9 TMEM189 COPS7A CCR6
27 congenital fiber-type disproportion 9.9 TPM4 TPM3 TPM2
28 myopathy, congenital 9.6 TPM3 TPM2
29 muscular disease 9.6 TPM3 TPM2 CCR6
30 congenital structural myopathy 9.6 TPM4 TPM3 TPM2 TPM1
31 corneal disease 9.6 TNFRSF10C CCR6
32 distal arthrogryposis 9.6 TPM4 TPM3 TPM2 TPM1
33 dilated cardiomyopathy 9.4 TPM4 TPM3 TPM2 TPM1
34 snail allergy 9.3 TPM4 TPM3 TPM2 TPM1 COPS7A
35 melon allergy 9.3 TPM4 TPM3 TPM2 TPM1 COPS7A
36 fish allergy 9.2 TPM4 TPM3 TPM2 TPM1 TMEM189

Graphical network of the top 20 diseases related to Shrimp Allergy:



Diseases related to Shrimp Allergy

Symptoms & Phenotypes for Shrimp Allergy

Drugs & Therapeutics for Shrimp Allergy

Drugs for Shrimp Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 9, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Immunologic Factors Phase 2
2
Chitosan Experimental 9012-76-4 71853
3 Hypolipidemic Agents
4 Anticholesteremic Agents
5 Chelating Agents
6 Coagulants
7 Hemostatics
8 Antimetabolites
9 Lipid Regulating Agents

Interventional clinical trials:

(showing 5, show less)
# Name Status NCT ID Phase Drugs
1 T Cell Reagent Research for Monitoring T Cells in Food Allergy (MOTIF) Phase 2 Study Using Food Allergen Oral Immunotherapy for Shrimp or Cashew Allergies Recruiting NCT03504774 Phase 2 Cashew or Shrimp Oral Immunotherapy
2 A Randomized Double-Blind Placebo-Controlled Crab Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques in NTU Campus Unknown status NCT02208414
3 Safety of Chitosan as Wine Fining Agent in Shrimp Allergic Patients Unknown status NCT02151279
4 The Utility of Serum Tryptase in the Diagnosis of Shrimp- Induced Anaphylaxis Completed NCT01619605
5 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813

Search NIH Clinical Center for Shrimp Allergy

Genetic Tests for Shrimp Allergy

Anatomical Context for Shrimp Allergy

MalaCards organs/tissues related to Shrimp Allergy:

40
T Cells, Skin, Testes

Publications for Shrimp Allergy

Articles related to Shrimp Allergy:

(showing 72, show less)
# Title Authors PMID Year
1
In vivo characterization of histological and immunological response of allergic protein of Metapenaeus dobsonii using an adjuvant free BALB/c mice model. 61
31809765 2019
2
T cell epitope of arginine kinase with CpG co-encapsulated nanoparticles attenuates a shrimp allergen-induced Th2-bias food allergy. 61
31795812 2019
3
Identification of allergic proteins of Flower tail shrimp (Metapenaeus dobsonii). 61
31749489 2019
4
Glycation by saccharides of different molecular sizes affected the allergenicity of shrimp tropomyosin via epitope loss and the generation of advanced glycation end products. 61
31580362 2019
5
Pen a 1-specific IgE does not improve the accuracy of a shrimp allergy diagnosis among Japanese children due to cross-reactivity with Der p 10. 61
31685384 2019
6
House dust mite allergy and shrimp allergy: a complex interaction. 61
31594291 2019
7
Modulating Shrimp Tropomyosin-Mediated Allergy: Hypoallergen DNA Vaccines Induce Regulatory T Cells to Reduce Hypersensitivity in Mouse Model. 61
31546958 2019
8
Defining specific allergens for improved component-resolved diagnosis of shrimp allergy in adults. 61
31247376 2019
9
Natural resolution of non-anaphylactic shrimp allergy in patients diagnosed 10 years earlier by oral food challenge. 61
31012598 2019
10
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy. 61
30597474 2019
11
Improved diagnostic clarity in shrimp allergic non-dust-mite sensitized patients. 61
30153888 2018
12
Identification of pyruvate kinase as a novel allergen in whiteleg shrimp (Litopenaeus vannamei) by specific-IgE present in patients with shrimp allergy. 61
29655746 2018
13
Oral food challenges: result of a 16-year experience at a major teaching hospital in Thailand. 61
29732297 2018
14
Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region. 61
29348432 2018
15
Shrimp allergy: beyond avoidance diet. 61
29249132 2017
16
Is mealworm or shrimp allergy indicative for food allergy to insects? 61
28500661 2017
17
[Effect of High Hydrostatic Pressure Combined with Temperature on the Antigenicity and Conformation of Tropomyosin Purified from Shrimp]. 61
30291771 2017
18
Allergen Valency, Dose, and FcεRI Occupancy Set Thresholds for Secretory Responses to Pen a 1 and Motivate Design of Hypoallergens. 61
28039304 2017
19
Shrimp Allergy: Analysis of Commercially Available Extracts for In Vivo Diagnosis. 61
27959286 2017
20
Low-Dose Allergen-Specific Immunotherapy Induces Tolerance in a Murine Model of Shrimp Allergy. 61
29065408 2017
21
Mite-Induced Asthma and IgE Levels to Shrimp, Mite, Tropomyosin, Arginine Kinase, and Der p 10 Are the Most Relevant Risk Factors for Challenge-Proven Shrimp Allergy. 61
29169170 2017
22
Cloning and characterization of recombinant tropomyosin of giant freshwater shrimp M. rosenbergii to determine major allergens causing allergic reactions among shrimp-allergic children. 61
27001653 2016
23
Shellfish and House Dust Mite Allergies: Is the Link Tropomyosin? 61
26739402 2016
24
T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. 61
26610061 2016
25
Shrimp allergy: Gastrointestinal symptoms commonly occur in the absence of IgE sensitization. 61
26563673 2016
26
Risk factors in pediatric shrimp allergy. 61
26108073 2015
27
Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity. 61
25769902 2015
28
Digestibility and Immunoreactivity of Shrimp Extracts Using an In Vitro Digestibility Model with Pepsin and Pancreatin. 61
26077284 2015
29
Stability and potency of raw and boiled shrimp extracts for skin prick test. 61
26141035 2015
30
Clinical and immunochemical profiles of food challenge proven or anaphylactic shrimp allergy in tropical Singapore. 61
25257922 2015
31
Gastrointestinal Immune Response to the Shrimp Allergen Tropomyosin: Histological and Immunological Analysis in an Animal Model of Shrimp Tropomyosin Hypersensitivity. 61
26112225 2015
32
Relationship between the risk for a shrimp allergy and freshness or cooking. 61
25966963 2015
33
Shrimp allergy beyond Tropomyosin in Italy: clinical relevance of Arginine Kinase, Sarcoplasmic calcium binding protein and Hemocyanin. 61
25224947 2014
34
Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis). 61
24996992 2014
35
New shrimp IgE-binding proteins involved in mite-seafood cross-reactivity. 61
24978201 2014
36
The utility of serum tryptase in the diagnosis of food-induced anaphylaxis. 61
24991453 2014
37
Immunization with Hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. 61
25365343 2014
38
[Identification of 70 kDa shrimp protein as a possible new allergen for shrimp allergy]. 61
24335423 2013
39
Structural and immunological characterization of recombinant Pan b 1, a major allergen of northern shrimp, Pandalus borealis. 61
23075760 2013
40
[Mass spectrometry identification and immune cross-reactivity of a minor shrimp allergen-sarcoplasmic calcium binding protein from Litopenaeus vannamei]. 61
22863586 2012
41
Is epitope recognition of shrimp allergens useful to predict clinical reactivity? 61
22192087 2012
42
Shrimp allergy in Italian adults: a multicenter study showing a high prevalence of sensitivity to novel high molecular weight allergens. 61
21894023 2012
43
Tropomyosin IgE-positive results are a good predictor of shrimp allergy. 61
21651567 2011
44
Improvement of shrimp allergy after sublingual immunotherapy for house dust mites: a case report. 61
22145252 2011
45
Safety of chitosan bandages in shellfish allergic patients. 61
22128651 2011
46
Immunoglobulin E-mediated food allergies among adults with allergic rhinitis. 61
20723775 2010
47
Greater epitope recognition of shrimp allergens by children than by adults suggests that shrimp sensitization decreases with age. 61
20471069 2010
48
[Identification, isolation, purification of allergens in shrimp and allergic analysis for the main allergens]. 61
20423651 2010
49
Measurement of IgE antibodies to shrimp tropomyosin is superior to skin prick testing with commercial extract and measurement of IgE to shrimp for predicting clinically relevant allergic reactions after shrimp ingestion. 61
20226506 2010
50
Determination of storage conditions for shrimp extracts: analysis of specific IgE-allergen profiles. 61
20527516 2010
51
Detection of a novel 20 kDa shrimp allergen showing cross-reactivity to house dust mites. 61
20355361 2010
52
Tropomyosin or not tropomyosin, what is the relevant allergen in house dust mite and snail cross allergies? 61
20355359 2010
53
Effects of boiling on the IgE-binding properties of tropomyosin of shrimp (Litopenaeus vannamei). 61
20492208 2010
54
Shellfish allergy in children. 61
19674349 2009
55
Myosin light chain is a novel shrimp allergen, Lit v 3. 61
18760458 2008
56
Specific allergy to Penaeus monodon (seawater shrimp) or Macrobrachium rosenbergii (freshwater shrimp) in shrimp-allergic children. 61
18498545 2008
57
Induction of shrimp tropomyosin-specific hypersensitivity in mice. 61
18617750 2008
58
Reactivity of shrimp allergy-related IgE antibodies to krill tropomyosin. 61
17912005 2008
59
[Characteristics of shrimp allergy from childhood to adulthood in Japan]. 61
17185914 2006
60
Do shrimp-allergic individuals tolerate shrimp-derived glucosamine? 61
17083356 2006
61
Effect of high intensity ultrasound on the allergenicity of shrimp. 61
16532525 2006
62
Structural, immunological and functional properties of natural recombinant Pen a 1, the major allergen of Brown Shrimp, Penaeus aztecus. 61
16630158 2006
63
Cross-reactivity among shrimp, crab and scallops in a patient with a seafood allergy. 61
16620221 2006
64
Mantis shrimp allergy. 61
17153890 2006
65
Food induced urticaria in children. 61
16572736 2005
66
Proteomics and immunological analysis of a novel shrimp allergen, Pen m 2. 61
12496430 2003
67
Prevalence of food allergies in young adults and their relationship to asthma, nasal allergies, and eczema. 61
11868923 2002
68
The relevance of specific serum IgG, IgG4 and IgE in the determination of shrimp and crab allergies in Malaysian allergic rhinitis patients. 61
11495303 2001
69
Effects of gamma radiation on the conformational and antigenic properties of a heat-stable major allergen in brown shrimp. 61
10914665 2000
70
IgE reactivity against a cross-reactive allergen in crustacea and mollusca: evidence for tropomyosin as the common allergen. 61
8939159 1996
71
Cloning, expression, and primary structure of Metapenaeus ensis tropomyosin, the major heat-stable shrimp allergen. 61
7963157 1994
72
Food specific skin-test reactivity in atopic subjects. 61
2758357 1989

Variations for Shrimp Allergy

Expression for Shrimp Allergy

Search GEO for disease gene expression data for Shrimp Allergy.

Pathways for Shrimp Allergy

GO Terms for Shrimp Allergy

Cellular components related to Shrimp Allergy according to GeneCards Suite gene sharing:

(showing 5, show less)
# Name GO ID Score Top Affiliating Genes
1 actin cytoskeleton GO:0015629 9.5 TPM3 TPM2 TPM1
2 stress fiber GO:0001725 9.33 TPM4 TPM3 TPM1
3 bleb GO:0032059 9.26 TPM1 SDF4
4 actin filament GO:0005884 9.26 TPM4 TPM3 TPM2 TPM1
5 muscle thin filament tropomyosin GO:0005862 8.92 TPM4 TPM3 TPM2 TPM1

Biological processes related to Shrimp Allergy according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 actin filament organization GO:0007015 9.46 TPM4 TPM3 TPM2 TPM1
2 muscle contraction GO:0006936 9.26 TPM4 TPM3 TPM2 TPM1
3 muscle filament sliding GO:0030049 8.92 TPM4 TPM3 TPM2 TPM1

Molecular functions related to Shrimp Allergy according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 actin binding GO:0003779 9.46 TPM4 TPM3 TPM2 TPM1
2 actin filament binding GO:0051015 9.26 TPM4 TPM3 TPM2 TPM1
3 structural constituent of muscle GO:0008307 8.8 TPM4 TPM2 TPM1

Sources for Shrimp Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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