MCID: SBR002
MIFTS: 22

Siberian Tick Typhus

Categories: Infectious diseases

Aliases & Classifications for Siberian Tick Typhus

MalaCards integrated aliases for Siberian Tick Typhus:

Name: Siberian Tick Typhus 12 15
North Asian Tick Typhus 12 70
Rickettsia Sibirica Spotted Fever 12
Spotted Fever Group Rickettsiosis 44
North Asian Tick Fever 12
Manchurian Typhus 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10921
ICD9CM 34 082.2
MeSH 44 D000073605
SNOMED-CT 67 7692008
ICD10 32 A77.2
UMLS 70 C0549160

Summaries for Siberian Tick Typhus

Disease Ontology : 12 A spotted fever that has material basis in Rickettsia sibirica, which is transmitted by ticks (Dermacentor nuttalli, Dermacentor marginatus and Haemaphysalis concinna). The infection has symptom fever, has symptom eschar, has symptom regional adenopathy, and has symptom maculopapular rash.

MalaCards based summary : Siberian Tick Typhus, also known as north asian tick typhus, is related to queensland tick typhus and exanthem, and has symptoms including fever, maculopapular rash and eschar. An important gene associated with Siberian Tick Typhus is PLEKHG4 (Pleckstrin Homology And RhoGEF Domain Containing G4). Related phenotypes are Decreased viability and Decreased viability

Wikipedia : 73 North Asian tick typhus also known as Siberian tick typhus, is a condition characterized by a... more...

Related Diseases for Siberian Tick Typhus

Diseases related to Siberian Tick Typhus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 queensland tick typhus 29.9 PUS10 PLEKHG4
2 exanthem 10.6
3 scrub typhus 10.4
4 african tick-bite fever 10.3
5 endemic typhus 10.3
6 dengue disease 10.3
7 boutonneuse fever 10.3
8 spotted fever rickettsiosis 10.3
9 dengue virus 10.2
10 indian tick typhus 10.2
11 flinders island spotted fever 10.2
12 japanese spotted fever 10.2
13 purpura fulminans 10.2
14 typhoid fever 10.2
15 purpura 10.2
16 lymphopenia 10.2
17 connective tissue disease 10.2
18 bap1 tumor predisposition syndrome 10.2
19 splenomegaly 10.2
20 rocky mountain spotted fever 10.1
21 epidemic typhus 10.1
22 spotted fever 10.1
23 israeli tick typhus 9.8 PUS10 PLEKHG4
24 astrakhan spotted fever 9.8 PUS10 CMPK1

Graphical network of the top 20 diseases related to Siberian Tick Typhus:



Diseases related to Siberian Tick Typhus

Symptoms & Phenotypes for Siberian Tick Typhus

Symptoms:

12
  • fever
  • maculopapular rash
  • eschar
  • regional adenopathy

GenomeRNAi Phenotypes related to Siberian Tick Typhus according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.17 INSRR
2 Decreased viability GR00221-A-2 9.17 CMPK1
3 Decreased viability GR00221-A-4 9.17 CMPK1
4 Decreased viability GR00301-A 9.17 CMPK1 INSRR
5 Decreased viability GR00342-S-1 9.17 CMPK1
6 Decreased viability GR00386-A-1 9.17 CMPK1

Drugs & Therapeutics for Siberian Tick Typhus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Epidemiology Of Scrub Typhus And Rickettsial Infections In A Highly Endemic Rural Setting In South India: Population-Based Cohort Study Recruiting NCT04506944

Search NIH Clinical Center for Siberian Tick Typhus

Cochrane evidence based reviews: spotted fever group rickettsiosis

Genetic Tests for Siberian Tick Typhus

Anatomical Context for Siberian Tick Typhus

Publications for Siberian Tick Typhus

Articles related to Siberian Tick Typhus:

(show all 14)
# Title Authors PMID Year
1
A fatal case of tick-borne rickettsiosis caused by mixed Rickettsia sibirica subsp. sibirica and "Candidatus Rickettsia tarasevichiae" infection in Russia. 61
31477530 2019
2
Genetic variability of Rickettsia spp. in Dermacentor and Haemaphysalis ticks from the Russian Far East. 61
30121164 2018
3
[Evaluation of the effectiveness of the serological methods for the identification of antibodies in patients with tissue ricketsiosis on the territories of a different risk of Rickettsia sibirica infection.] 61
30785693 2018
4
New evidence on tick-borne rickettsioses in the Altai region of Russia using primary lesions, serum and blood clots of molecular and serological study. 61
26344602 2015
5
[Human granulocytic anaplasmosis and its concurrence with other tick-borne infections in the Republic of Altai]. 61
25924278 2013
6
Sequence and annotation of Rickettsia sibirica sibirica genome. 61
22493192 2012
7
Rickettsial diseases in Russia. 61
17114680 2006
8
Methods of isolation and cultivation of new Rickettsiae from the Nosoarea of the north Asian tick typhus in Siberia. 61
17114789 2006
9
Molecular identification of a collection of spotted Fever group rickettsiae obtained from patients and ticks from Russia. 61
16525104 2006
10
Rickettsia sibirica infection in members of scientific expeditions to northern Asia. 61
14568744 2003
11
Biological and genetic characterization of Rickettsia sibirica strains isolated in the endemic area of the north Asian tick typhus. 61
9025699 1996
12
[Clinico-epidemiological characteristics of North Asian tick-borne exanthematous typhus]. 61
2370761 1990
13
Rickettsioses of the spotted fever group around the world. 61
2677080 1989
14
[Rickettsia of the Rocky Mountain spotted fever group and the agent of Siberian tick typhus]. 61
13150106 1953

Variations for Siberian Tick Typhus

Expression for Siberian Tick Typhus

Search GEO for disease gene expression data for Siberian Tick Typhus.

Pathways for Siberian Tick Typhus

GO Terms for Siberian Tick Typhus

Cellular components related to Siberian Tick Typhus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bicellular tight junction GO:0005923 8.62 TJAP1 CYTH1

Molecular functions related to Siberian Tick Typhus according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 guanyl-nucleotide exchange factor activity GO:0005085 8.62 PLEKHG4 CYTH1

Sources for Siberian Tick Typhus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....