MCID: SGM002
MIFTS: 25

Sigmoid Neoplasm

Categories: Cancer diseases, Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Sigmoid Neoplasm

MalaCards integrated aliases for Sigmoid Neoplasm:

Name: Sigmoid Neoplasm 12 15 17
Sigmoid Neoplasms 44 70
Neoplasm of Sigmoid Colon 12
Tumor of Sigmoid Colon 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1896
MeSH 44 D012811
SNOMED-CT 67 254581007
UMLS 70 C0037073

Summaries for Sigmoid Neoplasm

MalaCards based summary : Sigmoid Neoplasm, also known as sigmoid neoplasms, is related to intestinal obstruction and ovarian cystadenoma. An important gene associated with Sigmoid Neoplasm is ZNF750 (Zinc Finger Protein 750). The drugs Udenafil and Cola have been mentioned in the context of this disorder. Affiliated tissues include colon and liver.

Related Diseases for Sigmoid Neoplasm

Diseases related to Sigmoid Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 264)
# Related Disease Score Top Affiliating Genes
1 intestinal obstruction 29.1 KRT7 KRT20 CEACAM5 CDX2
2 ovarian cystadenoma 10.2 KRT7 CEACAM5
3 syringoma 10.1 KRT7 CEACAM5
4 leukoplakia of penis 10.1 KRT7 CEACAM5
5 laryngeal mucoepidermoid carcinoma 10.1 CEACAM5 CDX2
6 malignant acrospiroma 10.1 KRT7 CEACAM5
7 cutaneous mucoepidermoid carcinoma 10.1 KRT7 CEACAM5
8 external ear carcinoma 10.1 KRT7 CEACAM5
9 vulval paget's disease 10.1 KRT7 CEACAM5
10 eccrine adenocarcinoma 10.1 KRT7 CEACAM5
11 renal pelvis adenocarcinoma 10.1 KRT7 CEACAM5
12 bile duct cystadenocarcinoma 10.1 KRT7 CEACAM5
13 papillary squamous carcinoma 10.1 KRT7 CEACAM5
14 adenoid basal cell carcinoma 10.1 KRT7 CEACAM5
15 biliary papillomatosis 10.1 KRT7 CEACAM5
16 bile duct mucoepidermoid carcinoma 10.1 KRT7 CEACAM5
17 pericardium cancer 10.1 KRT7 CEACAM5
18 clear cell hidradenoma 10.1 KRT7 CEACAM5
19 hidradenoma 10.1 KRT7 CEACAM5
20 hidrocystoma 10.1 KRT7 CEACAM5
21 liver sarcoma 10.1 KRT7 CEACAM5
22 eccrine papillary adenocarcinoma 10.1 KRT7 CEACAM5
23 papillary adenocarcinoma 10.1 KRT7 CEACAM5
24 eccrine acrospiroma 10.1 KRT7 CEACAM5
25 eccrine sweat gland neoplasm 10.1 KRT7 CEACAM5
26 sarcomatous intrahepatic cholangiocarcinoma 10.1 KRT7 CEACAM5
27 ovary neuroendocrine neoplasm 10.1 KRT7 CDX2
28 cutaneous adenocystic carcinoma 10.1 KRT7 CEACAM5
29 anal canal paget's disease 10.1 KRT7 CDX2
30 gastric signet ring cell adenocarcinoma 10.1 KRT7 CDX2
31 colon neuroendocrine neoplasm 10.1 CEACAM5 CDX2
32 anal gland adenocarcinoma 10.1 KRT7 CDX2
33 anus adenocarcinoma 10.1 KRT7 CDX2
34 adenosquamous colon carcinoma 10.1 KRT7 CDX2
35 bartholin's gland disease 10.1 KRT7 CDX2
36 apocrine sweat gland neoplasm 10.1 KRT7 CEACAM5
37 bartholin's gland carcinoma 10.1 KRT7 CDX2
38 mucinous intrahepatic cholangiocarcinoma 10.1 KRT7 CDX2
39 ovarian seromucinous carcinoma 10.1 KRT7 CDX2
40 rectum neuroendocrine neoplasm 10.1 KRT7 CDX2
41 eccrine porocarcinoma 10.1 KRT7 CEACAM5
42 mediastinal cancer 10.1 KRT7 CEACAM5
43 keratinizing squamous cell carcinoma 10.1 KRT7 CEACAM5
44 malignant spiradenoma 10.1 KRT7 CEACAM5
45 signet ring basal cell carcinoma 10.1 KRAS CEACAM5
46 immature teratoma of ovary 10.1 KRAS CEACAM5
47 pancreatic cystadenocarcinoma 10.1 KRAS CEACAM5
48 urachal adenocarcinoma 10.1 KRAS CEACAM5
49 secretory meningioma 10.1 KRT7 CEACAM5
50 klatskin's tumor 10.1 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Sigmoid Neoplasm:



Diseases related to Sigmoid Neoplasm

Symptoms & Phenotypes for Sigmoid Neoplasm

Drugs & Therapeutics for Sigmoid Neoplasm

Drugs for Sigmoid Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Udenafil Approved, Investigational Phase 2 268203-93-6 6918523
2 Cola Phase 2
3 Phosphodiesterase 5 Inhibitors Phase 2
4 Phosphodiesterase Inhibitors Phase 2

Interventional clinical trials:

(show all 11)
# Name Status NCT ID Phase Drugs
1 Efficacy of Udenafil in Treatment of Erectile Dysfunction After Radical Resection for Sigmoid Colon and Rectal Cancer : a Randomized Controlled Trial Completed NCT00607282 Phase 2 Udenafil
2 Five Year Oncological Outcome After Complete Mesocolic Excision for Sigmoid Colon Cancer: a Population-based Cohort Study Unknown status NCT03774134
3 Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers Unknown status NCT02222844
4 Quality of Life After Colorectal Surgery: A Prospective Study of Patients Compared With Their Spouses Completed NCT04744792
5 The Effects of Mechnikov Probiotics on Symptom and Surgical Outcome After Anterior Resection of Colon Cancer; Double-blind, Randomized, Placebo-controlled Trial Completed NCT03531606 Mechnicov probiotics;Placebo
6 Interfraction and Intrafraction Organ Motion of the Sigmoid Colon in Patients With Colorectal Cancer Undergoing Adjuvant Radiotherapy Completed NCT03259828
7 A Study of Perfusion of Colorectal Anastomosis Using FLuorescence AnGiography (FLAG-trial) Completed NCT03390517
8 Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery - A Single-center Feasibility Pilot Study. Recruiting NCT03628248
9 Complete Mesocolon Excision vs Locoregional Lymphadenectomy in Sigmoid Colon Cancer (CMELL) Active, not recruiting NCT03083951
10 Prospective Comparative Multicentric Study, Assess the Quality of Life and Functionnal Results After Sigmoidectomy for Diverticulitis and Cancer Not yet recruiting NCT04729283
11 Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track Terminated NCT01127425

Search NIH Clinical Center for Sigmoid Neoplasm

Cochrane evidence based reviews: sigmoid neoplasms

Genetic Tests for Sigmoid Neoplasm

Anatomical Context for Sigmoid Neoplasm

MalaCards organs/tissues related to Sigmoid Neoplasm:

40
Colon, Liver

Publications for Sigmoid Neoplasm

Articles related to Sigmoid Neoplasm:

(show all 16)
# Title Authors PMID Year
1
Impact of 18F-2-fluoro-2-deoxy-D-glucose PET/computerized tomography on the initial staging and changing the management intent in head and neck squamous cell carcinoma. 61
33165255 2021
2
Laparoscopic en bloc removal of a sigmoid neoplasm infiltrating the left ureter, and uretero-vesical anastomosis on a Boari bladder flap-a video vignette. 61
33450115 2021
3
Management of Malignant Large-Bowel Obstruction. 61
31397752 2019
4
Non-absorbable suture granuloma mimicking a retroperitoneal metastatic implant in a patient with sigmoid neoplasm. 61
27615018 2016
5
A Case Report of Long-Term Survival following Hepatic Arterial Infusion of L-Folinic Acid Modulated 5-Fluorouracil Combined with Intravenous Irinotecan and Cetuximab Followed by Hepatectomy in a Patient with Initially Unresectable Colorectal Liver Metastases. 61
26064730 2015
6
New technique of intracorporeal anastomosis and transvaginal specimen extraction for laparoscopic sigmoid colectomy. 61
25169517 2014
7
Clinical correlates of health preference and generic health-related quality of life in patients with colorectal neoplasms. 61
23516465 2013
8
Inflammatory myofibroblastic tumor of the liver in an elderly woman following a second liver biopsy: a case report. 61
22111473 2011
9
Diseases that simulate acute appendicitis on ultrasound. 61
9534708 1998
10
[A rare case of coexistence of aneurysm of the abdominal aorta and sigmoid neoplasm]. 61
1295242 1992
11
Surgical procedures in colorectal cancer emergencies. 61
3201149 1988
12
[Acquired B antigen in a patient with a sigmoid neoplasm. The role of a pyocyanic bacterium?]. 61
7166997 1982
13
[Sigmoid neoplasms in patients with ureterosigmoidostomy]. 61
6275255 1981
14
[Indications and results in the author's own surgical experience of recto-sigmoid neoplasms]. 61
5499262 1970
15
[Ulcerative colitis secondary to partial stenosing sigmoid neoplasm]. 61
5739401 1968
16
[The abdominal route in the surgical treatment of recto-sigmoid neoplasms]. 61
15442359 1950

Variations for Sigmoid Neoplasm

Expression for Sigmoid Neoplasm

Search GEO for disease gene expression data for Sigmoid Neoplasm.

Pathways for Sigmoid Neoplasm

GO Terms for Sigmoid Neoplasm

Sources for Sigmoid Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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