MCID: SLN001
MIFTS: 26

Silent Myocardial Infarction

Categories: Cardiovascular diseases

Aliases & Classifications for Silent Myocardial Infarction

MalaCards integrated aliases for Silent Myocardial Infarction:

Name: Silent Myocardial Infarction 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:5854
NCIt 50 C35400
UMLS 72 C0340324

Summaries for Silent Myocardial Infarction

MalaCards based summary : Silent Myocardial Infarction is related to myocardial infarction and cerebrovascular disease. An important gene associated with Silent Myocardial Infarction is CDH4 (Cadherin 4), and among its related pathways/superpathways is Ca, cAMP and Lipid Signaling. The drugs Chromium and Cobalt have been mentioned in the context of this disorder. Affiliated tissues include heart, kidney and brain.

Related Diseases for Silent Myocardial Infarction

Diseases related to Silent Myocardial Infarction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 myocardial infarction 29.9 TNNI3 APOA1 AGTR1
2 cerebrovascular disease 29.0 APOA1 AGTR1
3 heart disease 28.9 TNNI3 APOA1 AGTR1
4 acute myocardial infarction 28.8 TNNI3 APOA1 AGTR1
5 coronary artery anomaly 28.6 TNNI3 APOA1 AGTR1
6 congestive heart failure 10.3
7 mitral valve insufficiency 10.2
8 aneurysm 10.2
9 graves disease 1 10.1
10 coronary heart disease 1 10.1
11 ischemia 10.1
12 lupus erythematosus 10.1
13 systemic lupus erythematosus 10.1
14 ocular motor apraxia 10.1
15 autonomic neuropathy 10.1
16 heart septal defect 10.1
17 pericarditis 10.1
18 antiphospholipid syndrome 10.1
19 vasculitis 10.1
20 neuropathy 10.1
21 diabetes mellitus 10.1
22 atherosclerosis susceptibility 9.9
23 progressive familial heart block, type ia 9.9
24 cardiac conduction defect 9.9
25 diabetes mellitus, noninsulin-dependent 9.9
26 hypercholesterolemia, familial, 1 9.9
27 rheumatoid arthritis 9.9
28 stroke, ischemic 9.9
29 kawasaki disease 9.9
30 hyperlipoproteinemia, type iii 9.9
31 angina pectoris 9.9
32 atrial fibrillation 9.9
33 left bundle branch hemiblock 9.9
34 pulmonary edema 9.9
35 hemopericardium 9.9
36 cardiac tamponade 9.9
37 pericardial effusion 9.9
38 coronary artery vasospasm 9.9
39 coronary thrombosis 9.9
40 graves' disease 9.9
41 acute cystitis 9.9
42 patent foramen ovale 9.9
43 toxic shock syndrome 9.9
44 hypoglycemic coma 9.9
45 ventricular septal defect 9.9
46 transient cerebral ischemia 9.9
47 coronary aneurysm 9.9
48 kidney disease 9.9
49 peripheral nervous system disease 9.9
50 inferior myocardial infarction 9.9

Graphical network of the top 20 diseases related to Silent Myocardial Infarction:



Diseases related to Silent Myocardial Infarction

Symptoms & Phenotypes for Silent Myocardial Infarction

Drugs & Therapeutics for Silent Myocardial Infarction

Drugs for Silent Myocardial Infarction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Chromium Approved Phase 4 7440-47-3 27668
2
Cobalt Approved, Experimental Phase 4 7440-48-4 104729
3 Nutrients Phase 4
4 Micronutrients Phase 4
5 Trace Elements Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A French, Multicentric, Randomized, Simple Blind, Superiority Study Comparing the Efficiency and the Safety at 24 Months of the Stent Titan2 Versus Bare Metal Stent in Cobalt-Chrome in All Comers Patients Among Which 40 % Present an ACS. Unknown status NCT01918150 Phase 4
2 MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA Unknown status NCT02517944
3 Clinical and Experimental Pain Perception is Attenuated in Patients With Painless Myocardial Infarction Completed NCT00192790
4 Incidence of Diabetes and Cardiovascular Disease in Mexican Americans Completed NCT00005205

Search NIH Clinical Center for Silent Myocardial Infarction

Genetic Tests for Silent Myocardial Infarction

Anatomical Context for Silent Myocardial Infarction

MalaCards organs/tissues related to Silent Myocardial Infarction:

41
Heart, Kidney, Brain, Lung, Skin, Testes, Endothelial

Publications for Silent Myocardial Infarction

Articles related to Silent Myocardial Infarction:

(show top 50) (show all 236)
# Title Authors PMID Year
1
Serum Cotinine and Silent Myocardial Infarction in Individuals Free from Cardiovascular Disease. 38
31272704 2019
2
Serum apolipoproteins and apolipoprotein-defined lipoprotein subclasses: a hypothesis-generating prospective study of cardiovascular events in T1D. 38
31203233 2019
3
Electrocardiographic definition of silent myocardial infarction in population studies: A call to standardize the standards. 38
31170595 2019
4
Association of Silent Myocardial Infarction and Sudden Cardiac Death. 38
31290935 2019
5
A silent myocardial infarction with normal coronary arteries associated with Graves' disease. 38
30503299 2019
6
Silent myocardial infarction and risk of heart failure: Current evidence and gaps in knowledge. 38
30224236 2019
7
Congestive heart failure caused by silent ischemia and silent myocardial infarction : Diagnostic challenge in type 2 diabetes. 38
30899966 2019
8
Incidentally discovered left ventricular pseudoaneurysm after silent myocardial infarction occurred in a young woman with peritoneal dialysis. 38
30859192 2019
9
Interrelationships Between American Heart Association's Life's Simple 7, ECG Silent Myocardial Infarction, and Cardiovascular Mortality. 38
30859894 2019
10
Interrelations Between Serum Uric Acid, Silent Myocardial Infarction, and Mortality in the General Population. 38
30617009 2019
11
One quarter of total myocardial infarctions are silent manifestation in patients with type 2 diabetes mellitus. 38
30487058 2019
12
Long-Term Prognostic Implications of Previous Silent Myocardial Infarction in Patients Presenting With Acute Myocardial Infarction. 38
29680352 2018
13
Silent myocardial infarction and risk of heart failure. 38
30613610 2018
14
Knockdown the P2X3 receptor in the stellate ganglia of rats relieved the diabetic cardiac autonomic neuropathy. 38
30196147 2018
15
An unusual etiology of ischemic stroke: Woven coronary artery anomaly. 38
30072841 2018
16
A Case of Left Ventricular Thrombus with Superior Mesenteric Vein Thrombosis Due to Atopic Dermatitis. 38
29877306 2018
17
Unruptured giant left ventricular pseudoaneurysm after silent myocardial infarction. 38
30021745 2018
18
Acute coronary syndromes: Silent myocardial infarction increases the risk of heart failure. 38
29368702 2018
19
Correction: Sudden death associated with silent myocardial infarction in a 35-year-old man: a case report. 38
29471871 2018
20
Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment. 38
29359025 2018
21
Silent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study. 38
29301615 2018
22
Prolonged diabetic ketoacidosis associated with canagliflozin. 38
29899991 2018
23
Silent Myocardial Infarction: Listen to the Evidence. 38
29301632 2018
24
A Combination of Tachycardia-Mediated Heart Failure and Coronary Artery Vasospasm-Induced Silent Myocardial Infarction in a Patient with Severe Thyrotoxicosis. 38
29713551 2018
25
Sickle-cell and alpha-thalassemia traits resulting in non-atherosclerotic myocardial infarction: Beyond coincidence? 38
29291201 2017
26
Prognostic value of silent myocardial infarction in patients with chronic kidney disease being evaluated for kidney transplantation. 38
28958755 2017
27
Woven coronary anomaly leading to silent myocardial infarction: A case report. 38
29095260 2017
28
Reperfusion treatment delays amongst patients with painless ST segment elevation myocardial infarction. 38
27681496 2017
29
Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study. 38
28515002 2017
30
Removal of a giant left ventricular thrombus after myocardial infarction due to dissection of left anterior descending artery. 38
28329239 2017
31
SAVOR-TIMI to SUSTAIN-6: a critical comparison of cardiovascular outcome trials of antidiabetic drugs. 38
28121469 2017
32
Systemic Amyloidosis and Cardiac Autonomic Neuropathy Associated with Waldenstrom's Macroglobulinemia. 38
28695027 2017
33
Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals. 38
27924924 2016
34
A Novel and Practical Screening Tool for the Detection of Silent Myocardial Infarction in Patients With Type 2 Diabetes. 38
27300573 2016
35
Erratum to: Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. 38
27376356 2016
36
Silent myocardial infarction secondary to cardiac autonomic neuropathy in a patient with rheumatoid arthritis. 38
27489064 2016
37
Cardiovascular Events in a Physical Activity Intervention Compared With a Successful Aging Intervention: The LIFE Study Randomized Trial. 38
27439082 2016
38
[Prognosis of silent myocardial infarction]. 38
30547496 2016
39
Severe adverse events associated with local anaesthesia in cataract surgery: 1 year national survey of practice and complications in the UK. 38
26405103 2016
40
Association of cardiovascular disease risk factors with left ventricular mass, biventricular function, and the presence of silent myocardial infarction on cardiac MRI in an asymptomatic population. 38
27209284 2016
41
Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study. 38
27185168 2016
42
Sudden death associated with silent myocardial infarction in a 35-year-old man: a case report. 38
26925778 2016
43
Inferior Q waves in apparently healthy subjects: Should we take a deep breath? An electrocardiographic, echocardiographic and cardiac magnetic resonance study. 38
26387880 2016
44
Transient Receptor Potential Vanilloid Subtype 1 Inhibits Inflammation and Apoptosis via the Release of Calcitonin Gene-Related Peptide in the Heart after Myocardial Infarction. 38
27144592 2016
45
Cardiovascular safety of albiglutide in the Harmony programme: a meta-analysis. 38
26276240 2015
46
A rare long-term survival of the life-threatening trio: silent myocardial infarction complicated by ventricular septal rupture, type 2 diabetes mellitus and chronic bronchitis. 38
26543616 2015
47
Heart rate and systolic blood pressure variability on recently diagnosed diabetics. 38
26176187 2015
48
Acute renal infarction associated with homozygous methylenetetrahydrofolate reductase mutation C677T and IgA beta-2-glycoprotein antibodies. 38
25828971 2015
49
Silent myocardial infarction and stroke: findings of multimodality imaging. 38
25514927 2015
50
Unrecognised myocardial infarction in patients with schizophrenia. 38
25582655 2015

Variations for Silent Myocardial Infarction

Expression for Silent Myocardial Infarction

Search GEO for disease gene expression data for Silent Myocardial Infarction.

Pathways for Silent Myocardial Infarction

Pathways related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.73 TNNI3 APOA1

GO Terms for Silent Myocardial Infarction

Biological processes related to Silent Myocardial Infarction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of cholesterol esterification GO:0010873 8.62 APOA1 AGTR1

Sources for Silent Myocardial Infarction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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