MCID: SNS011
MIFTS: 21

Sinus Cancer

Categories: Cancer diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Sinus Cancer

MalaCards integrated aliases for Sinus Cancer:

Name: Sinus Cancer 52 71

Classifications:



External Ids:

UMLS 71 C3534577

Summaries for Sinus Cancer

MalaCards based summary : Sinus Cancer is related to paranasal sinus cancer and maxillary sinus cancer. The drugs Cisplatin and Etoposide have been mentioned in the context of this disorder. Affiliated tissues include eye, lymph node and bone.

Related Diseases for Sinus Cancer

Diseases in the Sinus Cancer family:

Frontal Sinus Cancer

Diseases related to Sinus Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 paranasal sinus cancer 12.4
2 maxillary sinus cancer 12.4
3 pyriform sinus cancer 12.4
4 ethmoid sinus cancer 12.4
5 frontal sinus cancer 12.4
6 paranasal sinus cancer, adult 12.2
7 sphenoidal sinus cancer 12.2
8 ethmoid sinus adenocarcinoma 11.5
9 adenoid cystic carcinoma 10.0
10 olfactory neuroblastoma 9.9
11 maxillary cancer 9.9
12 maxillary sinus squamous cell carcinoma 9.9
13 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.9
14 adenocarcinoma 9.9
15 squamous cell papilloma 9.8
16 papilloma 9.8
17 inverted papilloma 9.8
18 neuroblastoma 9.8
19 hard palate cancer 9.8
20 retinal detachment 9.6
21 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.6
22 yemenite deaf-blind hypopigmentation syndrome 9.6
23 severe cutaneous adverse reaction 9.6
24 erythema multiforme 9.6
25 mucositis 9.6
26 dry eye syndrome 9.6
27 osteonecrosis 9.6
28 nasal cavity cancer 9.6
29 neutropenia 9.6
30 anodontia 9.6
31 squamous cell carcinoma 9.6
32 neuroendocrine carcinoma 9.6
33 rhabdomyosarcoma 9.6
34 macular retinal edema 9.6
35 rhinitis 9.6
36 mucoepidermoid carcinoma 9.6
37 adenosquamous carcinoma 9.6
38 myoepithelial carcinoma 9.6
39 nasal cavity squamous cell carcinoma 9.6
40 chronic rhinitis 9.6
41 hypopharynx cancer 9.6
42 tongue cancer 9.6
43 48,xyyy 9.6
44 oral cancer 9.6
45 supraglottic laryngeal cancer 9.6
46 dysphagia 9.6
47 acute sensory ataxic neuropathy 9.6
48 erythema multiforme major 9.6
49 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.6

Graphical network of the top 20 diseases related to Sinus Cancer:



Diseases related to Sinus Cancer

Symptoms & Phenotypes for Sinus Cancer

Drugs & Therapeutics for Sinus Cancer

Drugs for Sinus Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
2
Etoposide Approved Phase 2 33419-42-0 36462
3
Fluorouracil Approved Phase 2 51-21-8 3385
4
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
5
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
6 Topoisomerase Inhibitors Phase 2
7 Etoposide phosphate Phase 2
8 Immunologic Factors Phase 2
9 Antimitotic Agents Phase 2
10 Immunosuppressive Agents Phase 2
11 Antimetabolites Phase 2
12
Motexafin gadolinium Investigational Phase 1 246252-06-2, 156436-89-4 12047567
13 Dermatologic Agents Phase 1
14 Photosensitizing Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase II, Single-Arm Trial Assessing Local Control of Near Total Endoscopic Resection Followed by Concurrent Chemotherapy and Proton Radiation in the Treatment of Unresectable Sinonasal Tumors Recruiting NCT03274414 Phase 2 Cisplatin;cisplatin and etoposide
2 Predictive Methods Determining Tumour Hypoxia in Head and Neck Cancer Patients - a Prospective Project Recruiting NCT02414048 Phase 2 Pimonidazole
3 Phase II Trial of Induction Therapy With Docetaxel, Cisplatin and Fluorouracil in Previously Untreated Patients With Locally Advanced Squamous Cell Carcinoma and/or Poorly Differentiated Carcinoma of the Nasal Cavity and/or Paranasal Sinuses Recruiting NCT00707473 Phase 2 Carboplatin;Cisplatin;Docetaxel;Fluorouracil
4 Phase II Randomized Trial of Neo-Adjuvant Chemotherapy Followed by Surgery and Post-Operative Radiation Versus Surgery and Post-Operative Radiation for Organ Preservation of T3 and T4a Nasal and Paranasal Sinus Squamous Cell Carcinoma (NPNSCC) Recruiting NCT03493425 Phase 2 Carboplatin;Cisplatin;Docetaxel
5 Phase II Study of Antineoplastons A10 and AS2-1 In Patients With Carcinoma of the Head and Neck Terminated NCT00003489 Phase 2 Antineoplaston therapy (Atengenal + Astugenal)
6 Phase I Trial of Motexafin Gadolinium and Chemoradiation in Locally Advanced, Squamous Cell Carcinoma of the Head and Neck Terminated NCT00080028 Phase 1 Motexafin Gadolinium Injection
7 Preoperative Radiotherapy and Concomitant Chemotherapy Followed by Surgery for Advanced Paranasal Sinus Carcinoma Withdrawn NCT00347256 cisplatin

Search NIH Clinical Center for Sinus Cancer

Genetic Tests for Sinus Cancer

Anatomical Context for Sinus Cancer

MalaCards organs/tissues related to Sinus Cancer:

40
Eye, Lymph Node, Bone, Lung, Neutrophil, Tongue

Publications for Sinus Cancer

Articles related to Sinus Cancer:

(show top 50) (show all 276)
# Title Authors PMID Year
1
[Reconstruction of orbital floor defect with preserved orbital contents after advanced maxillary sinus cancer resection]. 61
31954385 2020
2
Sinonasal Undifferentiated Carcinoma in a Patient Previously Treated for an Intestinal-Type Adenocarcinoma: Metachronous Neoplasms or Recurrence of a Different Tumor Type? 61
31763244 2019
3
Dose distribution of intensity-modulated proton therapy with and without a multi-leaf collimator for the treatment of maxillary sinus cancer: a comparative effectiveness study. 61
31752928 2019
4
Therapeutic efficacy of regional and systemic chemotherapy in advanced maxillary sinus cancer. 61
30924582 2019
5
Definitive Radiation Therapy Versus Postoperative Radiation Therapy for Patients With Maxillary Sinus Cancer Invading the Upper Jaw. 61
30882578 2019
6
Salvage surgery for a locally persistent or recurrent tumour in maxillary cancer patients who have undergone radiotherapy and concomitant intra-arterial cisplatin: implications for surgical margin assessment. 61
30447876 2019
7
Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus. 61
30296902 2019
8
Oncological and functional outcomes of trans-oral robotic surgery for pyriform sinus carcinoma: A French GETTEC group study. 61
30409296 2018
9
The Synergistic Effect of Immune Checkpoint Blockade and Radiotherapy in Recurrent/Metastatic Sinonasal Cancer. 61
30648054 2018
10
Combined transoral-transhyoid endoscopic approach for hypopharyngeal cancer. 61
29402609 2018
11
Dose-finding and efficacy confirmation trial of the superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for locally advanced maxillary sinus cancer (Japan Clinical Oncology Group 1212): Dose-finding phase. 61
29130565 2018
12
Options of medical treatment and laryngeal function preservation in elderly patients with medial wall pyriform sinus cancer. 61
30464497 2018
13
Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea. 61
29423230 2018
14
Results of preoperative chemoradiotherapy for patients with advanced cancer of the nasal cavity and paranasal sinuses. 61
28749194 2017
15
[Surgical management of elderly patients with medial wall pyriform sinus cancer]. 61
29262511 2017
16
Recurrent maxillary sinus cancer with only adrenal metastasis. 61
29181177 2017
17
Managing head and neck malignancy arising in a field of Crohn disease inflammation: Report of a case. 61
29121377 2017
18
[Transcatheter arterial embolization in the treatment of maxillary artery pseudoaneurysm hemorrhage: a case report]. 61
29798258 2017
19
Intraoperative Change in Defect Size during Maxillary Reconstruction Using Surgical Guides Created by CAD/CAM. 61
28507870 2017
20
Prognostic value of pretreatment peripheral blood markers in paranasal sinus cancer: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. 61
28032937 2017
21
Therapeutic Management of Pyriform Sinus Cancer. 61
28072556 2017
22
Cancer incidence among copper smelting and nickel refining workers in Finland. 61
27747921 2017
23
Chronic Sinusitis and Risk of Head and Neck Cancer in the US Elderly Population. 61
27606895 2017
24
Single-center retrospective series of fourteen patients with mucosal melanoma of the nasal cavity and paranasal sinuses. 61
27502822 2016
25
[Nasal cavity and paranasal sinus cancer]. 61
27528562 2016
26
Impact of Endoscopic Indocyanine Green Fluorescence Imaging on Superselective Intra-arterial Chemotherapy for Recurrent Cancer of the Skull Base. 61
27354602 2016
27
Transoral robotic surgery for early T classification hypopharyngeal cancer. 61
26559383 2016
28
SUVmax on FDG-PET is a predictor of prognosis in patients with maxillary sinus cancer. 61
26920841 2016
29
Treatment outcomes of intensity-modulated radiotherapy versus 3D conformal radiotherapy for patients with maxillary sinus cancer in the postoperative setting. 61
25538027 2016
30
Paranasal sinus cancer. 61
26520459 2016
31
Long-term changes in quality of life after endoscopic resection of sinonasal and skull-base tumors. 61
26249825 2015
32
[A Case of Stevens-Johnson Syndrome Developing during Chemoradiotherapy for Maxillary Sinus Cancer]. 61
26964396 2015
33
Estimation of the planning organ at risk volume for the lenses during radiation therapy for nasal cavity and paranasal sinus cancer. 61
26238510 2015
34
Clinical outcomes of weekly cisplatin chemoradiotherapy for patients with pyriform sinus cancer. 61
25804347 2015
35
[Efficacy of endoscopic nasal lateral wall dissection approach in the treatment of maxillary sinus diseases]. 61
26513994 2015
36
Successful treatment of quintuple primary cancer, including esophageal cancer: A case report. 61
26137110 2015
37
Multi-institutional retrospective study for the evaluation of ocular function-preservation rates in maxillary sinus squamous cell carcinomas with orbital invasion. 61
24715544 2015
38
Functional evaluation of a CAD/CAM prosthesis for immediate defect repair after total maxillectomy: a case series of 18 patients with maxillary sinus cancer. 61
25345998 2015
39
Dose-finding and efficacy confirmation trial of superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for patients with locally advanced maxillary sinus cancer (JCOG1212, RADPLAT-MSC). 61
25332419 2015
40
Effect of local extension sites on survival in locally advanced maxillary sinus cancer. 61
23996685 2014
41
Dose distribution resulting from changes in aeration of nasal cavity or paranasal sinus cancer in the proton therapy. 61
25245554 2014
42
Significant improvement in superselective intra-arterial chemotherapy for advanced paranasal sinus cancer by using indocyanine green fluorescence. 61
24318470 2014
43
The incidence of late neck recurrence in N0 maxillary sinus squamous cell carcinomas after superselective intra-arterial chemoradiotherapy without prophylactic neck irradiation. 61
24213278 2014
44
A pyriform sinus cancer organ preservation strategy comprising induction chemotherapy with docetaxel, cisplatin, and 5-fluorouracil, followed by potentiated radiotherapy: a multicenter, retrospective study. 61
24849707 2014
45
A dosimetric comparison of volumetric modulated arc therapy (VMAT) and non-coplanar intensity modulated radiotherapy (IMRT) for nasal cavity and paranasal sinus cancer. 61
25175383 2014
46
Primary carcinoma of the frontal sinus with extensive intracranial invasion: A case report and review of the literature. 61
24932258 2014
47
Superselective intra-arterial cisplatin infusion and concomitant radiotherapy for maxillary sinus cancer. 61
24196792 2013
48
Paranasal sinus cancer. 61
23523040 2013
49
Postradiation sarcoma from a free flap. 61
24220428 2013
50
Neoadjuvant intra-arterial chemotherapy combined with radiotherapy and surgery in patients with advanced maxillary sinus cancer. 61
24137556 2013

Variations for Sinus Cancer

Expression for Sinus Cancer

Search GEO for disease gene expression data for Sinus Cancer.

Pathways for Sinus Cancer

GO Terms for Sinus Cancer

Sources for Sinus Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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