MCID: SNS011
MIFTS: 24

Sinus Cancer

Categories: Cancer diseases, Rare diseases, Respiratory diseases
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Aliases & Classifications for Sinus Cancer

MalaCards integrated aliases for Sinus Cancer:

Name: Sinus Cancer 19 75 71

Classifications:



External Ids:

UMLS 71 C3534577

Summaries for Sinus Cancer

GARD: 19 A carcinoma arising from the nasal cavity or paranasal sinuses.

MalaCards based summary: Sinus Cancer is related to paranasal sinus cancer and maxillary sinus cancer. The drugs Raspberry and Carboplatin have been mentioned in the context of this disorder. Affiliated tissues include lymph node, eye and lung.

Wikipedia: 75 Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The... more...

Related Diseases for Sinus Cancer

Diseases in the Sinus Cancer family:

Frontal Sinus Cancer

Diseases related to Sinus Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 paranasal sinus cancer 11.4
2 maxillary sinus cancer 11.3
3 pyriform sinus cancer 11.3
4 ethmoid sinus cancer 11.3
5 frontal sinus cancer 11.2
6 paranasal sinus cancer, adult 11.2
7 sphenoidal sinus cancer 11.1
8 ethmoid sinus adenocarcinoma 11.0
9 head and neck cancer 10.2
10 adenoid cystic carcinoma 10.1
11 maxillary cancer 10.1
12 maxillary sinus squamous cell carcinoma 10.0
13 neurodegeneration with brain iron accumulation 2a 10.0
14 squamous cell carcinoma 10.0
15 adenocarcinoma 10.0
16 spastic paraplegia, intellectual disability, nystagmus, and obesity 9.9
17 papilloma 9.9
18 inverted papilloma 9.9
19 olfactory neuroblastoma 9.9
20 48,xyyy 9.9
21 abducens palsy 9.7
22 retinal detachment 9.7
23 factor vii deficiency 9.7
24 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.7
25 rhabdomyosarcoma 2 9.7
26 stroke, ischemic 9.7
27 nasopharyngeal carcinoma 9.7
28 spastic paraplegia, ataxia, and mental retardation 9.7
29 severe cutaneous adverse reaction 9.7
30 tatton-brown-rahman syndrome 9.7
31 ptosis 9.7
32 mucositis 9.7
33 tongue carcinoma 9.7
34 dry eye syndrome 9.7
35 osteonecrosis 9.7
36 common cold 9.7
37 nasal cavity cancer 9.7
38 human papillomavirus infectious disease 9.7
39 keratomalacia 9.7
40 cauda equina syndrome 9.7
41 bronchus cancer 9.7
42 glanders 9.7
43 anodontia 9.7
44 neuroendocrine carcinoma 9.7
45 optic nerve disease 9.7
46 melanoma 9.7
47 transient cerebral ischemia 9.7
48 larynx cancer 9.7
49 laryngeal benign neoplasm 9.7
50 rhabdomyosarcoma 9.7

Graphical network of the top 20 diseases related to Sinus Cancer:



Diseases related to Sinus Cancer

Symptoms & Phenotypes for Sinus Cancer

Drugs & Therapeutics for Sinus Cancer

Drugs for Sinus Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Raspberry Approved Phase 1, Phase 2
2
Carboplatin Approved Phase 2 41575-94-4 10339178 38904
3
Fluorouracil Approved Phase 2 51-21-8 3385
4
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
5
Cisplatin Approved Phase 2 15663-27-1 2767 5702198 441203
6
Etoposide Approved Phase 2 33419-42-0 36462
7 Antimitotic Agents Phase 2
8 Antimetabolites Phase 2
9 Tubulin Modulators Phase 2
10 Immunosuppressive Agents Phase 2
11 Immunologic Factors Phase 2
12
Etoposide phosphate Phase 2 16760419
13
Rocuronium Approved 119302-91-9, 143558-00-3 441290
14
Lidocaine Approved, Vet_approved 137-58-6 3676
15
Isoflurane Approved, Vet_approved 26675-46-7 3763
16
Sevoflurane Approved, Vet_approved 28523-86-6 5206
17
Remifentanil Approved 132875-61-7 60815
18
Fentanyl Approved, Illicit, Investigational, Vet_approved 437-38-7 3345
19
Tranexamic acid Approved 1197-18-8 5526
20
Succinylcholine Approved 306-40-1, 71-27-2 5314
21
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
22
Clove Approved 84961-50-2
23 Analgesics
24 Antifibrinolytic Agents
25 Anesthetics, Intravenous
26 Anesthetics, Inhalation
27 Anesthetics, General
28 Anesthetics
29 Hypnotics and Sedatives
30 Analgesics, Opioid
31 Hemostatics
32 Coagulants
33 Narcotics
34 Eucalyptus

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Prospective Non-Inferiority Trial of the Use of Adaptive Radiotherapy for Head and Neck Cancer Undergoing Radiation Therapy Completed NCT03096808 Phase 2
2 Food-Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer Completed NCT01469429 Phase 1, Phase 2 chemoprevention
3 Phase II Trial of Induction Therapy With Docetaxel, Cisplatin and Fluorouracil in Previously Untreated Patients With Locally Advanced Squamous Cell Carcinoma and/or Poorly Differentiated Carcinoma of the Nasal Cavity and/or Paranasal Sinuses Recruiting NCT00707473 Phase 2 Carboplatin;Cisplatin;Docetaxel;Fluorouracil
4 Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses: a Phase II Multicenter Study Recruiting NCT05114707 Phase 2 camrelizumab
5 A Phase II, Single-Arm Trial Assessing Local Control of Near Total Endoscopic Resection Followed by Concurrent Chemotherapy and Proton Radiation in the Treatment of Unresectable Sinonasal Tumors Active, not recruiting NCT03274414 Phase 2 Cisplatin;cisplatin and etoposide
6 Integrated Cancer Repository for Cancer Research Recruiting NCT02012699
7 Prospective Observational Single Arm Study of Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal Sinus Recruiting NCT05614375
8 The Observational Clinical Registry of the European Reference Network on Rare Adult Solid Cancers: the Protocol for the Rare Head and Neck Cancers Recruiting NCT05483374
9 Comparison of Inhalational Anesthesia With Intravenous Tranexamic Acid and Total Intravenous Anesthesia on Surgical Field Quality in Endoscopic Sinus Surgery Not yet recruiting NCT05639686 Tranexamic acid injection;Total Intravenous Anesthesia;Inhalational isoflurane
10 Olfactory Training For Post Radiation Olfactory Loss In Patients With Paranasal Sinus and Nasopharyngeal Carcinoma Terminated NCT03049358

Search NIH Clinical Center for Sinus Cancer

Genetic Tests for Sinus Cancer

Anatomical Context for Sinus Cancer

Organs/tissues related to Sinus Cancer:

MalaCards : Lymph Node, Eye, Lung, Bone, Neutrophil

Publications for Sinus Cancer

Articles related to Sinus Cancer:

(show top 50) (show all 313)
# Title Authors PMID Year
1
Treatment of electroplating industry wastewater: a review on the various techniques. 62
35084684 2022
2
Outcomes of Patients Undergoing Emergency Tracheostomy During COVID 19 Pandemic: Our Experience from a Tertiary Care Centre in North-East India. 62
33686367 2022
3
Lymph node ratio predicts recurrence-free survival and disease-specific survival of patients with pyriform sinus squamous cell carcinoma. 62
36184282 2022
4
Relationship between Chronic Rhinosinusitis and the Incidence of Head and Neck Cancer: A National Population-Based Study. 62
36142963 2022
5
Photoimmunotherapy with surgical navigation and computed tomography guidance for recurrent maxillary sinus carcinoma. 62
36123249 2022
6
Associations of Body Mass Index and Waist Circumference with the Risk of Head and Neck Cancer: A National Population-Based Study. 62
36010881 2022
7
Organ preservation surgery for pyriform sinus carcinoma with vocal cord fixation: functional and oncological outcomes. 62
34825265 2022
8
Palatal mucoperiosteal flap for oro-nasal fistula following maxillectomy for maxillary sinus cancer. 62
35778286 2022
9
Impact of Socioeconomic Status on Paranasal Sinus Cancer Disease-Specific and Conditional Survival. 62
34281443 2022
10
Regression of advanced maxillary sinus cancer with orbital invasion by combined chemotherapy and immunotherapy: A one-year follow-up case report. 62
35350406 2022
11
A case of maxillary cancer treated by intra-arterial therapy using a steerable microcatheter. 62
33412974 2022
12
Organized Hematoma after Intra-Arterial Chemoradiotherapy for Maxillary Sinus Cancer: A Case Report. 62
35392701 2022
13
Salvage surgery improves the treatment outcome of patients with residual/recurrent maxillary sinus cancer after superselective intra-arterial cisplatin infusion with concomitant radiation therapy. 62
33866400 2022
14
Free double-paddle superficial circumflex iliac perforator flap transfer for partial maxillectomy reconstruction: A case report. 62
34617610 2022
15
A domain knowledge enhanced yield based deep learning classifier identifies perineural invasion in oral cavity squamous cell carcinoma. 62
36353548 2022
16
Case report: 18F-FDG PET confirmed pupil-sparing third nerve palsy heralding aseptic cavernous sinus embolism in patient with chest malignancy. 62
36117807 2022
17
A long-term survival case with proton beam therapy for advanced sphenoid sinus cancer with hypopituitarism. 62
35116220 2022
18
Occupational exposure to hexavalent chromium. Part II. Hazard assessment of carcinogenic effects. 62
34506880 2021
19
Racial and ethnic disparities in paranasal sinus malignancies. 62
34096200 2021
20
Radiologic criteria of retropharyngeal lymph node metastasis in maxillary sinus cancer. 62
34565434 2021
21
Imaging predictor of ophthalmic involvement in maxillary sinus cancer during super selective intra-arterial cisplatin infusion and concomitant radiotherapy (RADPLAT). 62
34399796 2021
22
The incidence of myocardial infarction and stroke in head and neck cancer patients. 62
33603026 2021
23
A Systematic Review of Proton Therapy for the Management of Nasopharyngeal Cancer. 62
34285941 2021
24
Invasion of the pterygoid plates: an indicator for regional lymph node failure in maxillary sinus cancer. 62
33407616 2021
25
Pathological evaluation of radiotherapy and concomitant intraarterial cisplatin for maxillary sinus cancer. 62
32359864 2020
26
Treatment Outcome and Patterns of Failure in Patients with Maxillary Sinus Cancer: Clinical Experience from a Regional Cancer Centre in North India. 62
33013118 2020
27
["Point line anterograde dissection" for the safe preparation of supraclavicular flap]. 62
32911887 2020
28
Malignant tumors of the maxillary sinus: Prognostic impact of neurovascular invasion in a series of 138 patients. 62
32298995 2020
29
PI3K/AKT/mTOR pathway and autophagy regulator genes in paranasal squamous cell carcinoma metastasis. 62
32319010 2020
30
A rare case of cerebral hemorrhage associated with intra-arterial infusion chemotherapy for advanced sphenoid sinus cancer. 62
32719293 2020
31
Establishment and characterization of patient-derived xenografts as paraclinical models for head and neck cancer. 62
32293356 2020
32
[Reconstruction of orbital floor defect with preserved orbital contents after advanced maxillary sinus cancer resection]. 62
31954385 2020
33
Metabolism and Functions of Amino Acids in Sense Organs. 62
32761578 2020
34
Dose distribution of intensity-modulated proton therapy with and without a multi-leaf collimator for the treatment of maxillary sinus cancer: a comparative effectiveness study. 62
31752928 2019
35
Sinonasal Undifferentiated Carcinoma in a Patient Previously Treated for an Intestinal-Type Adenocarcinoma: Metachronous Neoplasms or Recurrence of a Different Tumor Type? 62
31763244 2019
36
Therapeutic efficacy of regional and systemic chemotherapy in advanced maxillary sinus cancer. 62
30924582 2019
37
Definitive Radiation Therapy Versus Postoperative Radiation Therapy for Patients With Maxillary Sinus Cancer Invading the Upper Jaw. 62
30882578 2019
38
Salvage surgery for a locally persistent or recurrent tumour in maxillary cancer patients who have undergone radiotherapy and concomitant intra-arterial cisplatin: implications for surgical margin assessment. 62
30447876 2019
39
Survival Outcomes for Induction vs Adjuvant Chemotherapy in Squamous Cell Carcinoma of the Maxillary Sinus. 62
30296902 2019
40
Analysis of expression of p63 and caspase-3 and their predictive value in patients with squamous cell carcinoma of maxillary sinus. 62
32124745 2019
41
Oncological and functional outcomes of trans-oral robotic surgery for pyriform sinus carcinoma: A French GETTEC group study. 62
30409296 2018
42
The Synergistic Effect of Immune Checkpoint Blockade and Radiotherapy in Recurrent/Metastatic Sinonasal Cancer. 62
30648054 2018
43
Combined transoral-transhyoid endoscopic approach for hypopharyngeal cancer. 62
29402609 2018
44
Dose-finding and efficacy confirmation trial of the superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for locally advanced maxillary sinus cancer (Japan Clinical Oncology Group 1212): Dose-finding phase. 62
29130565 2018
45
Review of carcinogenicity of hexavalent chrome and proposal of revising approval standards for an occupational cancers in Korea. 62
29423230 2018
46
Options of medical treatment and laryngeal function preservation in elderly patients with medial wall pyriform sinus cancer. 62
30464497 2018
47
[Surgical management of elderly patients with medial wall pyriform sinus cancer]. 62
29262511 2017
48
Results of preoperative chemoradiotherapy for patients with advanced cancer of the nasal cavity and paranasal sinuses. 62
28749194 2017
49
Recurrent maxillary sinus cancer with only adrenal metastasis. 62
29181177 2017
50
Managing head and neck malignancy arising in a field of Crohn disease inflammation: Report of a case. 62
29121377 2017

Variations for Sinus Cancer

Expression for Sinus Cancer

Search GEO for disease gene expression data for Sinus Cancer.

Pathways for Sinus Cancer

GO Terms for Sinus Cancer

Sources for Sinus Cancer

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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