Aliases & Classifications for Sinusitis

MalaCards integrated aliases for Sinusitis:

Name: Sinusitis 38 29 55 43 63 73

Classifications:



External Ids:

UMLS 73 C0037199

Summaries for Sinusitis

MedlinePlus : 43 Sinusitis means your sinuses are inflamed. The cause can be an infection or another problem. Your sinuses are hollow air spaces within the bones surrounding the nose. They produce mucus, which drains into the nose. If your nose is swollen, this can block the sinuses and cause pain. There are several types of sinusitis, including Acute, which lasts up to 4 weeks Subacute, which lasts 4 to 12 weeks Chronic, which lasts more than 12 weeks and can continue for months or even years Recurrent, with several attacks within a year Acute sinusitis often starts as a cold, which then turns into a bacterial infection. Allergies, nasal problems, and certain diseases can also cause acute and chronic sinusitis. Symptoms of sinusitis can include fever, weakness, fatigue, cough, and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. Your health care professional diagnoses sinusitis based on your symptoms and an examination of your nose and face. You may also need imaging tests. Treatments include antibiotics, decongestants, and pain relievers. Using heat pads on the inflamed area, saline nasal sprays, and vaporizers can also help. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Sinusitis is related to common cold and allergic bronchopulmonary aspergillosis, and has symptoms including angina pectoris, coughing and fever. An important gene associated with Sinusitis is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Augmentin and Avelox I.V. have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and skin, and related phenotypes are digestive/alimentary and immune system

PubMed Health : 63 About sinusitis: Sinusitis is an inflammation of the paranasal sinuses. The full medical term for sinusitis is "rhinosinusitis" ("rhino-" meaning "nose"), because it affects the mucous membranes lining both the nose and the sinuses.The paranasal sinuses are part of the upper airways, and are connected to the nasal cavity. They are made up of several cavities in the skull found from the forehead down to the teeth of the upper jaw. Depending on where they are, these cavities are known as the frontal sinuses, the sphenoid sinus, the ethmoid cells and the maxillary sinuses. The paranasal sinuses are lined with mucous membranes that have tiny hairs (ciliated epithelium). These mucous membranes produce a secretion that runs down through the nose and throat.

Wikipedia : 76 Sinusitis, also known as a sinus infection or rhinosinusitis, is inflammation of the sinuses resulting... more...

Related Diseases for Sinusitis

Diseases in the Sinusitis family:

Chronic Frontal Sinusitis Frontal Sinusitis
Acute Frontal Sinusitis

Diseases related to Sinusitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 471)
# Related Disease Score Top Affiliating Genes
1 common cold 32.5 CXCL8 IL5 RNASE3
2 allergic bronchopulmonary aspergillosis 30.9 CFTR IL5
3 cystic fibrosis 30.5 CFTR CXCL8 DEFB4A RNASE3
4 intrinsic asthma 29.8 IL5 RNASE3
5 respiratory system disease 29.7 CFTR CXCL8 CYSLTR1 IL5 RNASE3
6 cellulitis 29.6 DEFB4A IL5 RNASE3
7 milk allergy 29.5 IL5 RNASE3
8 churg-strauss syndrome 29.5 IL5 RNASE3
9 status asthmaticus 29.5 CXCL8 IL5 RNASE3
10 conjunctivitis 29.5 CXCL8 IL5 RNASE3
11 allergic rhinitis 29.4 CXCL8 IL4R IL5 RNASE3
12 bronchitis 29.3 CFTR CXCL8 IL5 RNASE3
13 food allergy 29.0 IL5 RNASE3
14 rhinitis 28.8 CXCL8 CYSLTR1 IL4R IL5 RNASE3
15 asthma 26.9 CFTR CXCL8 CYSLTR1 IL4R IL5 LTC4S
16 maxillary sinusitis 12.4
17 sphenoid sinusitis 12.4
18 frontal sinusitis 12.4
19 ethmoid sinusitis 12.4
20 chronic maxillary sinusitis 12.3
21 acute maxillary sinusitis 12.3
22 acute frontal sinusitis 12.3
23 chronic frontal sinusitis 12.3
24 chronic sphenoidal sinusitis 12.3
25 acute sphenoidal sinusitis 12.3
26 rokitansky-aschoff sinuses of the gallbladder 12.0
27 microcornea, glaucoma, and absent frontal sinuses 11.9
28 chronic ethmoiditis 11.9
29 acute ethmoiditis 11.7
30 kartagener syndrome 11.7
31 sinonasal undifferentiated carcinoma 11.7
32 young syndrome 11.5
33 squamous cell carcinoma, head and neck 11.4
34 primary ciliary dyskinesia 11.3
35 inverted papilloma 11.3
36 wegener granulomatosis 11.2
37 yellow nail syndrome 11.2
38 phaeohyphomycosis 11.2
39 ciliary dyskinesia, primary, 1 11.1
40 orbital cellulitis 11.1
41 aspergillosis 11.1
42 cavernous sinus thrombosis 11.1
43 paranasal sinus disease 11.1
44 nasopharyngitis 11.0
45 pharyngitis 11.0
46 fibrous dysplasia 11.0
47 van der woude syndrome 1 11.0
48 adenoid cystic carcinoma 11.0
49 zygomycosis 11.0
50 myeloid sarcoma 11.0

Graphical network of the top 20 diseases related to Sinusitis:



Diseases related to Sinusitis

Symptoms & Phenotypes for Sinusitis

UMLS symptoms related to Sinusitis:


angina pectoris, coughing, fever, halitosis, headache, pruritus, snoring, tinnitus, tremor, sinus congestion, sore throat, vertigo/dizziness, equilibration disorder

MGI Mouse Phenotypes related to Sinusitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.55 IL12RB2 IL4R IL5 BTK CFTR
2 immune system MP:0005387 9.5 CYSLTR1 IL12RB2 IL4R IL5 LTC4S BTK
3 respiratory system MP:0005388 9.02 CYSLTR1 IL4R IL5 LTC4S CFTR

Drugs & Therapeutics for Sinusitis

PubMedHealth treatment related to Sinusitis: 63

Steroidal or decongestant nasal sprays may relieve discomfort in patients with sinusitis. Nasal irrigation or inhalation may also help, and antibiotics may be an option in some cases.In case of chronic inflammation, one common treatment is surgery to expand narrowed paranasal sinus passageways. This is an option if steroid sprays and other treatments do not provide enough relief.

FDA approved drugs:

# Drug Name Active Ingredient(s) 18 Company Approval Date
1
Augmentin 18 AMOXICILLIN; CLAVULANATE POTASSIUM SmithKline Beecham February 1996
2
Avelox I.V. 18 MOXIFLOXACIN HYDROCHLORIDE Bayer November 2001
3
Biaxin XL 18 CLARITHROMYCIN Abbott Laboratories March 2000
4
Cipro 18 CIPROFLOXACIN HYDROCHLORIDE; HYDROCORTISONE Bayer June 1997
5
Tequin 18 Bristol-Myers Squibb December, 1999

Drugs for Sinusitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 319)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 26787-78-0 33613
2
Montelukast Approved Phase 4 158966-92-8 5281040
3
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
4
Remifentanil Approved Phase 4,Not Applicable 132875-61-7 60815
5
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
6
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
7
Cefditoren Approved, Investigational Phase 4 117467-28-4, 104145-95-1 9571074 9870843
8
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 53-03-2 5865
9
Ephedrine Approved Phase 4,Phase 2,Not Applicable 299-42-3 9294
10
Pseudoephedrine Approved Phase 4,Phase 2,Not Applicable 90-82-4 7028
11
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Not Applicable 51-43-4 5816
12
Racepinephrine Approved Phase 4,Phase 3,Not Applicable 329-65-7 838
13
Menthol Approved Phase 4,Phase 2,Not Applicable 2216-51-5 16666
14
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
15 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8
16
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
17
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
18
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
19
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
20
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2 242138-07-4
21
Cefdinir Approved Phase 4 91832-40-5 6915944
22
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
23
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
24
Telithromycin Approved Phase 4,Phase 3 191114-48-4 5462516 0
25
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
26
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
27
Acetaminophen Approved Phase 4,Phase 2,Phase 3,Not Applicable 103-90-2 1983
28
Dextromethorphan Approved Phase 4 125-71-3 5360696 5362449
29
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 2 93-14-1 3516
30
Budesonide Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 51333-22-3 63006 5281004
31
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Not Applicable 124-94-7 31307
32
Thrombin Approved, Investigational Phase 4
33
Cocaine Approved, Illicit Phase 4 50-36-2 5760 446220
34
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
35
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2 113775-47-6 68602 5311068
36
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
37
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
38
Almotriptan Approved, Investigational Phase 4 154323-57-6, 181183-52-8 123606
39
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
40
Clarithromycin Approved Phase 4,Phase 3,Not Applicable 81103-11-9 84029
41
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560
42
Etanercept Approved, Investigational Phase 4 185243-69-0
43
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
44
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
45
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
46
Oseltamivir Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 204255-11-8, 196618-13-0 65028
47
Cefuroxime Approved Phase 4,Phase 2 55268-75-2 5361202 5479529
48
Cefazolin Approved Phase 4 25953-19-9 656510 33255
49
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
50
Sulfamethoxazole Approved Phase 4,Phase 3 723-46-6 5329

Interventional clinical trials:

(show top 50) (show all 398)
# Name Status NCT ID Phase Drugs
1 The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis Unknown status NCT02582099 Phase 4 Gentamicin nasal irrigation;Normal saline nasal irrigation
2 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
3 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
4 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
5 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
6 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
7 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
8 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
9 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
10 Xolair in Patients With Chronic Sinusitis Completed NCT00117611 Phase 4 Anti-IgE antibody omalizumab or placebo
11 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
12 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life Completed NCT00147914 Phase 4 Cefdinir (drug);amoxicillin/clavulanate
13 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4 Telithromycin
14 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate
15 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
16 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
17 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
18 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
19 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
20 Study of Asthma and Nasal Steroids Completed NCT01118312 Phase 4 Mometasone Furoate monohydrate
21 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
22 The PIO II Study of In-office Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
23 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
24 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
25 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
26 Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers Completed NCT00208065 Phase 4 almotriptan or pseudoephedrine
27 The Effect of Packing in Post Operative Management of FESS Completed NCT00793117 Phase 4
28 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
29 Aizthromycin or Clarithromycin in H-pylori Eradication Regimen Completed NCT01667692 Phase 4 azithromycin;clarithmycin
30 The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis Completed NCT02696850 Phase 4 Budesonide;Saline alone
31 Study of Enbrel in Rheumatoid Arthritis (RA) Subjects With Comorbid Disorders Completed NCT00132418 Phase 4 Enbrel;Placebo
32 Telithromycin in Respiratory Tract Infections Completed NCT00261105 Phase 4 telithromycin
33 Proteomic Profiling for Influenza Completed NCT00133588 Phase 4
34 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Completed NCT02307825 Phase 4 Azithromycin;Placebo
35 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
36 Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Completed NCT02119273 Phase 4 Prednisone;Placebo
37 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis Completed NCT03086070 Phase 4 Omeprazole 20mg;Placebo oral capsule
38 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
39 Clinical Trial of Clinical Efficiency and Safety of Ergoferon in Treatment of Influenza Completed NCT01804946 Phase 4 Ergoferon;Oseltamivir
40 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix TM) Administered in Healthy Adolescents Completed NCT00534638 Phase 4
41 Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate Recruiting NCT03431337 Phase 4 Amoxicillin 875 mg
42 Response of the Airway in Sinusitis and Asthma Recruiting NCT03011632 Phase 4 Mometasone Nasal;placebo mometasone
43 Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions Recruiting NCT03014687 Phase 4 Placebo;Oral Antibiotics cefdinir or trimethoprim/sulfamethoxazole
44 Group A Pharyngitis in Children: The GASPARD Study Recruiting NCT03264911 Phase 4 Amoxicillin or Placebo
45 The Benefit and Harm of Fever Suppression by Antipyretics in Influenza Recruiting NCT01891084 Phase 4 Paracetamol;Placebo;Backup NSAID ibuprofen
46 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Active, not recruiting NCT01919411 Phase 4 Amoxicillin-Potassium Clavulanate;Placebo
47 Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study Active, not recruiting NCT00841802 Phase 4 Prednisone
48 Use of Perioperative Antibiotics in Endoscopic Sinus Surgery Not yet recruiting NCT03369717 Phase 4 Amoxi Clavulanate
49 Effect of OM-85 on Respiratory Tract Infections and Adenoid Tissue in Children With Adenoid Hypertrophy Not yet recruiting NCT03243565 Phase 4
50 Study to Measure the Impact of Antibiotics on Bacterial Flora in Adults With Acute Sinusitis Terminated NCT00245440 Phase 4 Azithromycin;Telithromycin

Search NIH Clinical Center for Sinusitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Genetic Tests for Sinusitis

Genetic tests related to Sinusitis:

# Genetic test Affiliating Genes
1 Sinusitis 29

Anatomical Context for Sinusitis

MalaCards organs/tissues related to Sinusitis:

41
Bone, Testes, Skin, Brain, Pituitary, Tonsil, Lymph Node

Publications for Sinusitis

Articles related to Sinusitis:

(show top 50) (show all 1863)
# Title Authors Year
1
Intracranial subdural abscess with polymicrobial infections due to frontal sinusitis in an adolescent: life-threatening complication of a common disease. ( 29531731 )
2018
2
Differences in expression of YKL-40 and TLR4 in nasal sinus mucosa of chronic sinusitis patients with and without nasal polyps. ( 29921378 )
2018
3
Orbital granulomatosis with polyangiitis masquerading as invasive fungal sinusitis. ( 29303390 )
2018
4
Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )
2018
5
Clinical implications of taste thresholds in patients with odontogenic maxillary sinusitis. ( 29174862 )
2018
6
Gene and protein expression of <i>CXCR4</i> in adult and elderly patients with chronic rhinitis, pharyngitis or sinusitis undergoing thermal water nasal inhalations. ( 29497453 )
2018
7
Pressure variations in cerebral venous sinuses of idiopathic intracranial hypertension patients. ( 29922401 )
2018
8
Intracranial complications of acute sinusitis in children: The role of endoscopic sinus surgery. ( 29859578 )
2018
9
Rapidly Developing Subdural Empyema in an Adult with Sinusitis: A Neurosurgical Threat Alert. ( 29682060 )
2018
10
Carotid dissection mimicking sinusitis. ( 29369929 )
2018
11
A phase 3 trial of mometasone furoate sinus implants for chronic sinusitis with recurrent nasal polyps. ( 29350840 )
2018
12
Ophthalmic Manifestations of Allergic Fungal Sinusitis. ( 29384825 )
2018
13
ACTUAL ISSUES OF ODONTOGENIC MAXILLARY SINUSITIS (REVIEW). ( 29697380 )
2018
14
Early life risk factors for chronic sinusitis: a longitudinal birth cohort study. ( 29355680 )
2018
15
Efficacy of sinus ultrasound in diagnosis of acute and subacute maxillary sinusitis. ( 29779998 )
2018
16
Inflammatory immune response in rabbits with Staphylococcus aureus biofilm-associated sinusitis. ( 29979838 )
2018
17
Comparison between the Effects of Oral and Intramuscular Administration of Shin'iseihaito (Xinyiqingfeitang) in a <i>Streptococcus pyogenes</i>-Induced Murine Sinusitis Model. ( 29853978 )
2018
18
Isolated abducens palsy due to acute sphenoid sinusitis. ( 29730382 )
2018
19
Appropriateness of antibiotic prescriptions for acute sinusitis and pharyngitis in an integrated healthcare system. ( 29807555 )
2018
20
A multi-institutional review of outcomes in biopsy-proven acute invasive fungal sinusitis. ( 29979836 )
2018
21
Is phage therapy suitable for treating chronic sinusitis Staphylococcus aureus infection? ( 29792517 )
2018
22
Brain abscess in a patient with chronic sinusitis. ( 29321201 )
2018
23
Olfactory dysfunction is worse in primary ciliary dyskinesia compared with other causes of chronic sinusitis in children. ( 29490941 )
2018
24
Anatomic measurements of cerebral venous sinuses in idiopathic intracranial hypertension patients. ( 29856739 )
2018
25
Preclinical therapeutic efficacy of the ciprofloxacin-eluting sinus stent for Pseudomonas aeruginosa sinusitis. ( 29334430 )
2018
26
Impact of residual frontal recess cells on frontal sinusitis after endoscopic sinus surgery. ( 29777294 )
2018
27
Cyclamen europaeum extract for acute sinusitis. ( 29750825 )
2018
28
Focus on the Involvement of the Nose and Paranasal Sinuses in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome): Nasal Cytology Reveals Infiltration of Eosinophils as a Very Common Feature. ( 29393242 )
2018
29
Role of Thermography in the Diagnosis of Chronic Sinusitis. ( 29755895 )
2018
30
High-dose versus standard-dose amoxicillin/clavulanate for clinically-diagnosed acute bacterial sinusitis: A randomized clinical trial. ( 29738561 )
2018
31
A computed tomographic analysis of frontal recess cells in association with the development of frontal sinusitis. ( 29880289 )
2018
32
Orbital apex syndrome from bacterial sinusitis without orbital cellulitis. ( 29468204 )
2018
33
Neurological Complications of Acute and Chronic Sinusitis. ( 29404826 )
2018
34
Treatment options for odontogenic maxillary sinusitis: a review. ( 29806655 )
2018
35
Failure of a Best Practice Alert to Reduce Antibiotic Prescribing Rates for Acute Sinusitis Across an Integrated Health System in the Midwest. ( 29384025 )
2018
36
Complicated Fusobacterium Sinusitis: A Case Report. ( 29389826 )
2018
37
Incidence of Sinusitis Associated With Endotracheal and Nasogastric Tubes: NIS Database. ( 29292272 )
2018
38
Odontogenic sinusitis: A review of the current literature. ( 29721543 )
2018
39
Small cell neuroendocrine carcinoma of nose and paranasal sinuses: The Shaukat Khanum Memorial Cancer Hospital experience and review of literature. ( 29371736 )
2018
40
Frontal sinusitis complicated by a brain abscess and subdural empyema. ( 29682134 )
2018
41
Two cases of extranasopharyngeal angiofibroma mimicking choanal polyp in patients with chronic paranasal sinusitis. ( 29954635 )
2018
42
IgG4-related disease: association between chronic rhino-sinusitis and systemic symptoms. ( 29948263 )
2018
43
Translation, validation, and cultural adaptation of the Rhinosinusitis Disability Index and the Chronic Sinusitis Survey into Arabic. ( 29848932 )
2018
44
NICE: reduce antibiotic prescribing for acute sinusitis. ( 29288146 )
2018
45
Improvement of psychiatric symptoms in youth following resolution of sinusitis. ( 28012531 )
2017
46
A Case of Fungus Ball-Type Maxillary Sinusitis Due to Penicillium Roqueforti. ( 29075960 )
2017
47
Use of computer-assisted design and manufacturing to localize dural venous sinuses during reconstructive surgery for craniosynostosis. ( 28921242 )
2017
48
Immunoglobulin G4 sinusitis in association with aspirin-exacerbated respiratory disease. ( 28859705 )
2017
49
Reply to the letter &amp;quot;Nasal nitric oxide as biomarker in the evaluation and management of chronic rhino-sinusitis with nasal polyposis&amp;quot;. ( 28866810 )
2017
50
Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man. ( 28491883 )
2017

Variations for Sinusitis

Expression for Sinusitis

LifeMap Discovery
Genes differentially expressed in tissues of Sinusitis patients vs. healthy controls: 35 (show all 38)
# Gene Description Tissue Up/Dn Fold Change (log2) P value
1 FDCSP follicular dendritic cell secreted protein Nose + 5.87 0.000
2 MUC7 mucin 7, secreted Nose + 5.43 0.001
3 PIP prolactin-induced protein Nose + 5.28 0.000
4 STATH statherin Nose + 5.17 0.000
5 KRT14 keratin 14, type I Nose + 4.90 0.000
6 CRISP3 cysteine-rich secretory protein 3 Nose + 4.46 0.007
7 C6orf58 chromosome 6 open reading frame 58 Nose + 4.30 0.002
8 BPIFB2 BPI fold containing family B, member 2 Nose + 4.26 0.002
9 IGHM immunoglobulin heavy constant mu Nose + 4.22 0.000
10 ZG16B zymogen granule protein 16B Nose + 3.91 0.000
11 LOC285628 MIR146A host gene Nose + 3.85 0.000
12 CXCL13 chemokine (C-X-C motif) ligand 13 Nose + 3.84 0.001
13 AZGP1 alpha-2-glycoprotein 1, zinc-binding Nose + 3.78 0.001
14 SEC14L3 SEC14-like lipid binding 3 Nose - 3.72 0.000
15 TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) Nose + 3.70 0.000
16 DSG3 desmoglein 3 Nose + 3.65 0.000
17 DMBT1 deleted in malignant brain tumors 1 Nose + 3.65 0.003
18 SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) Nose - 3.61 0.000
19 GREM2 gremlin 2, DAN family BMP antagonist Nose - 3.60 0.002
20 SLC26A4 solute carrier family 26 (anion exchanger), member 4 Nose + 3.55 0.001
21 PRB3 proline-rich protein BstNI subfamily 3 Nose + 3.55 0.001
22 LTF lactotransferrin Nose + 3.49 0.008
23 FLJ26850 FLJ26850 protein Nose - 3.49 0.000
24 NCAPG non-SMC condensin I complex, subunit G Nose + 3.48 0.000
25 DUOX2 dual oxidase 2 Nose + 3.43 0.007
26 MUC5B mucin 5B, oligomeric mucus/gel-forming Nose + 3.41 0.000
27 LPO lactoperoxidase Nose + 3.31 0.003
28 C15orf48 chromosome 15 open reading frame 48 Nose + 3.29 0.001
29 STK33 serine/threonine kinase 33 Nose - 3.28 0.008
30 CXCL5 chemokine (C-X-C motif) ligand 5 Nose + 3.20 0.001
31 CXorf57 chromosome X open reading frame 57 Nose - 3.16 0.002
32 ODAM odontogenic, ameloblast asssociated Nose + 3.12 0.007
33 IDO1 indoleamine 2,3-dioxygenase 1 Nose + 3.11 0.011
34 TF transferrin Nose + 3.11 0.000
35 CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) Nose + 3.11 0.003
36 PRB4 proline-rich protein BstNI subfamily 4 Nose + 3.09 0.005
37 LRP1B low density lipoprotein receptor-related protein 1B Nose - 3.06 0.003
38 CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 Nose - 3.04 0.001
Search GEO for disease gene expression data for Sinusitis.

Pathways for Sinusitis

Pathways related to Sinusitis according to GeneCards Suite gene sharing:

(show all 16)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.7 BTK CXCL8 DEFB4A IL12RB2 IL4R IL5
2
Show member pathways
13.29 BTK CXCL8 IL12RB2 IL4R IL5 LTC4S
3
Show member pathways
13.16 BTK CXCL8 IL12RB2 IL4R IL5
4
Show member pathways
13.05 BTK CXCL8 IL12RB2 IL4R IL5
5
Show member pathways
12.92 BTK CXCL8 IL12RB2 IL4R IL5
6 12.45 CXCL8 IL12RB2 IL4R IL5
7
Show member pathways
12.29 CXCL8 IL12RB2 IL4R IL5 RNASE3
8
Show member pathways
12.15 CXCL8 IL12RB2 IL4R IL5
9
Show member pathways
12.13 IL12RB2 IL4R IL5
10
Show member pathways
11.8 CFTR CXCL8 DEFB4A
11
Show member pathways
11.68 BTK CXCL8 IL4R IL5
12
Show member pathways
11.59 CFTR CXCL8 DEFB4A IL5
13 11.22 BTK CXCL8
14 11.01 IL4R IL5
15 10.46 IL12RB2 IL4R IL5
16