MCID: SKL001
MIFTS: 25

Skeletal Tuberculosis

Categories: Bone diseases, Infectious diseases

Aliases & Classifications for Skeletal Tuberculosis

MalaCards integrated aliases for Skeletal Tuberculosis:

Name: Skeletal Tuberculosis 12 15
Tuberculosis, Osteoarticular 44 73
Osteoarticular Tuberculosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1639
ICD10 33 A18.0
ICD9CM 35 015 015.9
MeSH 44 D014394
SNOMED-CT 68 17653001
UMLS 73 C0041324

Summaries for Skeletal Tuberculosis

Disease Ontology : 12 An extrapulmonary tuberculosis that results in formation of lesions located in bone.

MalaCards based summary : Skeletal Tuberculosis, also known as tuberculosis, osteoarticular, is related to mycobacterium tuberculosis 1 and extrapulmonary tuberculosis. An important gene associated with Skeletal Tuberculosis is SLC25A46 (Solute Carrier Family 25 Member 46). The drugs Antitubercular Agents and Deoxyglucose have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and bone marrow.

Related Diseases for Skeletal Tuberculosis

Diseases related to Skeletal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 mycobacterium tuberculosis 1 10.1
2 extrapulmonary tuberculosis 10.1
3 systemic lupus erythematosus 9.9
4 sjogren syndrome 9.9
5 tropical calcific pancreatitis 9.9
6 patulous eustachian tube 9.9
7 lupus erythematosus 9.9
8 slipped capital femoral epiphysis 9.9
9 gaucher disease, type iii 9.9 MT-CO3 SLC25A46
10 osteomyelitis 9.8
11 spondyloarthropathy 9.8
12 laryngeal tuberculosis 9.8 SLC25A46 SMUG1
13 leigh syndrome 9.8 MT-CO3 SLC25A46
14 langerhans cell histiocytosis 9.7
15 lyme disease 9.7
16 coccidioidomycosis 9.7
17 pulmonary tuberculosis 9.7
18 histiocytosis 9.7
19 paraplegia 9.7
20 pyomyositis 9.7
21 amyloidosis 9.7
22 bone marrow necrosis 9.7

Graphical network of the top 20 diseases related to Skeletal Tuberculosis:



Diseases related to Skeletal Tuberculosis

Symptoms & Phenotypes for Skeletal Tuberculosis

Drugs & Therapeutics for Skeletal Tuberculosis

Drugs for Skeletal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3
2 Deoxyglucose Not Applicable
3 Fluorodeoxyglucose F18 Not Applicable
4 Antimetabolites Not Applicable
5 Anti-Infective Agents Not Applicable
6 Antiviral Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months
2 Positron Emission Tomography in Extrapulmonary Tuberculosis Completed NCT01613196 Not Applicable

Search NIH Clinical Center for Skeletal Tuberculosis

Cochrane evidence based reviews: tuberculosis, osteoarticular

Genetic Tests for Skeletal Tuberculosis

Anatomical Context for Skeletal Tuberculosis

MalaCards organs/tissues related to Skeletal Tuberculosis:

41
Bone, Lung, Bone Marrow

Publications for Skeletal Tuberculosis

Articles related to Skeletal Tuberculosis:

(show top 50) (show all 127)
# Title Authors Year
1
Efficacy of alternate day Directly Observed Treatment Short-course (DOTS) in skeletal tuberculosis - A retrospective study. ( 29332653 )
2018
2
Drug resistant Skeletal Tuberculosis in a tertiary care centre in South India. ( 29628698 )
2018
3
The Epidemiology of Skeletal Tuberculosis in Northeast of Iran: A Review of 229 Cases. ( 30046206 )
2018
4
Multifocal Tubercular Dactylitis: A Rare Presentation of Skeletal Tuberculosis in an Adult. ( 28764233 )
2017
5
Skeletal Tuberculosis. ( 28155042 )
2017
6
Multifocal skeletal tuberculosis: A case report. ( 27073438 )
2016
7
Epidemiological features of skeletal tuberculosis at an urban district tuberculosis centre. ( 27451817 )
2016
8
Tuberculous Dactylitis: An Uncommon Presentation of Skeletal Tuberculosis. ( 27358553 )
2016
9
Multifocal skeletal tuberculosis in an immunocompetent patient: a case report. ( 26092386 )
2015
10
Multifocal Skeletal Tuberculosis Mimicking Langerhans Cell Histiocytosis in a Child: a Case Report With a Long-Term Follow-Up. ( 26744631 )
2015
11
Treatment paradox in musculo-skeletal tuberculosis in an immunocompetent adult male; a case report from a tertiary care hospital. ( 26046019 )
2015
12
Computed tomography detection of clinically unsuspected skeletal tuberculosis. ( 26338020 )
2015
13
FDG PET/CT in Monitoring Antituberculosis Therapy in Patient With Widespread Skeletal Tuberculosis. ( 26284767 )
2015
14
Coccidioidomycosis masquerading as skeletal tuberculosis: an imported case and review of coccidioidomycosis in India. ( 24265192 )
2014
15
The diagnosis of atypical skeletal tuberculosis is challenging. ( 25002383 )
2014
16
Potential role of F18 FDG PET-CT as an imaging biomarker for the noninvasive evaluation in uncomplicated skeletal tuberculosis: a prospective clinical observational study. ( 25070791 )
2014
17
18F-FDG PET/CT in a case of multifocal skeletal tuberculosis without pulmonary disease and potential role for monitoring treatment response. ( 24561689 )
2014
18
A case of skeletal tuberculosis and psoas abscess: disease activity evaluated using 18a88F-fluorodeoxyglucose positron emission tomography-computed tomography. ( 24225333 )
2013
19
Multifocal skeletal tuberculosis presenting as paraplegia: A case report. ( 23963266 )
2013
20
Tuberculous dactylitis (spina ventosa) with concomitant ipsilateral axillary scrofuloderma in an immunocompetent child: A rare presentation of skeletal tuberculosis. ( 23977657 )
2013
21
Skeletal tuberculosis presenting as a small cystic lesion in the medial femoral condyle. ( 25207301 )
2013
22
Skeletal tuberculosis following proximal tibia fracture. ( 23446371 )
2013
23
Multifocal skeletal tuberculosis involving the lumbar spine and iliac bone, mimicking a malignant bone tumour: a case report. ( 25279059 )
2012
24
Multifocal skeletal tuberculosis. ( 23275855 )
2012
25
Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI. ( 23064577 )
2012
26
Multifocal skeletal tuberculosis. ( 25874102 )
2012
27
Diagnostic performance of an enzyme-linked immunospot assay for interferon-I^ in skeletal tuberculosis. ( 21240673 )
2011
28
Multifocal skeletal tuberculosis masquerading as metastatic disease. ( 22295316 )
2011
29
New skeletal tuberculosis cases in past populations from Western Hungary (Transdanubia). ( 21530965 )
2011
30
Multifocal skeletal tuberculosis: experience in diagnosis and treatment. ( 19359113 )
2010
31
Multifocal skeletal tuberculosis in 2 immunocompetent children. ( 21041269 )
2010
32
Diagnostic role of whole body bone scintigraphy in atypical skeletal tuberculosis resembling multiple metastases: a case report. ( 19946546 )
2009
33
Multifocal skeletal tuberculosis in children. ( 19182762 )
2009
34
Pyomyositis with multifocal osteomyelitis--an uncommon presentation of skeletal tuberculosis. ( 20329428 )
2009
35
Skeletal tuberculosis in children in the Western world: 18 new cases with a review of the literature. ( 19543761 )
2009
36
Concomitant cutaneous metastatic tuberculous abscesses and multifocal skeletal tuberculosis. ( 19882018 )
2008
37
Pain in the elbow: a rare presentation of skeletal tuberculosis. ( 17964818 )
2008
38
Scapholunate dissociation: a rare presentation of TB wrist in a case of multi-focal skeletal tuberculosis. ( 18807747 )
2008
39
Multifocal skeletal tuberculosis presenting as multiple bone cysts. ( 18185888 )
2007
40
The prospect of incidental detection of unsuspected skeletal tuberculosis by bone scintigraphy should not be overlooked. ( 17515748 )
2007
41
Skeletal tuberculosis mimicking seronegative spondyloarthropathy. ( 18173033 )
2007
42
Multifocal skeletal tuberculosis: a report of three cases. ( 16789468 )
2006
43
Multifocal skeletal tuberculosis involving the lumbar spine and a sacroiliac joint: MR imaging findings. ( 16972219 )
2006
44
The use of real-time polymerase chain reaction for rapid diagnosis of skeletal tuberculosis. ( 16831035 )
2006
45
Multifocal skeletal tuberculosis with Rhodotorula minuta co-infection. ( 16718937 )
2006
46
Skeletal tuberculosis following fracture fixation. A report of five cases. ( 16651586 )
2006
47
Multifocal skeletal tuberculosis. ( 15352679 )
2004
48
Skeletal tuberculosis mimicking seronegative spondyloarthropathy. ( 12783178 )
2004
49
Skeletal tuberculosis in children. ( 15278319 )
2004
50
Multicentric skeletal tuberculosis in the absence of pulmonary disease. ( 15249833 )
2004

Variations for Skeletal Tuberculosis

Expression for Skeletal Tuberculosis

Search GEO for disease gene expression data for Skeletal Tuberculosis.

Pathways for Skeletal Tuberculosis

GO Terms for Skeletal Tuberculosis

Biological processes related to Skeletal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 8.62 AMELX SFTPB

Sources for Skeletal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....