Aliases & Classifications for Skin Atrophy

MalaCards integrated aliases for Skin Atrophy:

Name: Skin Atrophy 12 15 17
Atrophic Condition of Skin 12 71
Atrophoderma 12 74
Atrophy - Skin 12


External Ids:

Disease Ontology 12 DOID:2733
NCIt 49 C35163
SNOMED-CT 67 400190005
ICD10 32 L90
UMLS 71 C0151514

Summaries for Skin Atrophy

MalaCards based summary : Skin Atrophy, also known as atrophic condition of skin, is related to hallermann-streiff syndrome and werner syndrome. An important gene associated with Skin Atrophy is FERMT1 (Fermitin Family Member 1), and among its related pathways/superpathways are DNA Damage and Adhesion. The drugs mometasone furoate and Zinc have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and liver, and related phenotypes are cellular and growth/size/body region

Wikipedia : 74 Atrophoderma refers to conditions involving skin... more...

Related Diseases for Skin Atrophy

Diseases related to Skin Atrophy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 159)
# Related Disease Score Top Affiliating Genes
1 hallermann-streiff syndrome 32.1 ZMPSTE24 GJA1
2 werner syndrome 32.1 WRN RECQL4 LMNA
3 atypical werner syndrome 32.0 WRN LMNA
4 mandibuloacral dysplasia with type a lipodystrophy 31.8 ZMPSTE24 LMNA
5 rothmund-thomson syndrome, type 2 31.7 WRN RECQL4 ERCC6
6 keratosis 30.4 MBTPS2 LMNA GJA1 FLG
7 aging 30.0 WRN LMNA KL
8 ichthyosis 29.9 MBTPS2 LORICRIN GJA1 FLG ERCC6
9 calcinosis 29.6 ZMPSTE24 LMNA KL FGF23
10 skin disease 29.3 MMP1 LORICRIN LMNA HBEGF GJA1 FLG
11 alopecia 29.0 MBTPS2 LMNA GJA1
12 atrophoderma of pasini and pierini 12.8
13 atrophoderma vermiculata 12.7
14 bazex syndrome 12.4
15 follicular atrophoderma, perioral pigmented, with milia and epidermoid cysts 12.3
16 ichthyosis, congenital, autosomal recessive 11 12.0
17 flynn-aird syndrome 11.7
18 keratosis pilaris atrophicans 11.7
19 kindler syndrome 11.5
20 x-linked chondrodysplasia punctata 2 11.5
21 galloway-mowat syndrome 1 11.2
22 localized lipodystrophy 11.2
23 epidermolysis bullosa simplex, generalized, with scarring and hair loss 11.2
24 rombo syndrome 10.9
25 buerger disease 10.9
26 baller-gerold syndrome 10.9
27 cutis marmorata telangiectatica congenita 10.9
28 localized scleroderma 10.5
29 conjunctival deposit 10.5 KL FGF23
30 chronic actinic dermatitis 10.4 MMP1 FLG
31 nephrolithiasis/osteoporosis, hypophosphatemic, 1 10.4 KL FGF23
32 warthin tumor 10.4 HBEGF CD44
33 epidermolysis bullosa pruriginosa 10.4 MMP1 FLG
34 dental abscess 10.4 KL FGF23
35 familial tumoral calcinosis 10.4 KL FGF23
36 tracheal calcification 10.4 KL FGF23
37 pseudoainhum 10.4 LORICRIN GJA1
38 photoparoxysmal response 1 10.3 FERMT1 ERCC6
39 epidermolysis bullosa dystrophica 10.3 MMP1 FLG FERMT1
40 dowling-degos disease 1 10.3
41 hyperostosis 10.3 KL GJA1 FGF23
42 linear scleroderma 10.3
43 acroosteolysis 10.3 ZMPSTE24 LMNA
44 bone remodeling disease 10.3 KL FGF23 ERCC6
45 progeroid syndrome 10.3 WRN LMNA
46 laminopathy 10.3 ZMPSTE24 LMNA
47 hypervitaminosis d 10.3 TRPV5 KL FGF23
48 lichen sclerosus et atrophicus 10.2
49 ichthyosis, follicular 10.2
50 phosphorus metabolism disease 10.2 TRPV5 KL FGF23

Graphical network of the top 20 diseases related to Skin Atrophy:

Diseases related to Skin Atrophy

Symptoms & Phenotypes for Skin Atrophy

MGI Mouse Phenotypes related to Skin Atrophy:

45 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.34 CD44 ERCC6 FBLIM1 FERMT1 GJA1 KL
2 growth/size/body region MP:0005378 10.32 CD44 ERCC6 FERMT1 FGF23 GJA1 HBEGF
3 immune system MP:0005387 10.3 CABIN1 CD44 ERCC6 FBLIM1 FERMT1 FGF23
4 homeostasis/metabolism MP:0005376 10.29 CD44 ERCC6 FERMT1 FGF23 GJA1 HBEGF
5 hematopoietic system MP:0005397 10.27 CABIN1 CD44 ERCC6 FBLIM1 FGF23 GJA1
6 digestive/alimentary MP:0005381 10.24 CD44 FERMT1 FGF23 KL LMNA RECQL4
7 endocrine/exocrine gland MP:0005379 10.22 CD44 FBLIM1 FGF23 GJA1 KL LMNA
8 integument MP:0010771 10.21 CD44 ERCC6 FERMT1 FGF23 GJA1 HBEGF
9 mortality/aging MP:0010768 10.18 CABIN1 CD44 ERCC6 FERMT1 FGF23 GJA1
10 limbs/digits/tail MP:0005371 10.14 CD44 ERCC6 FBLIM1 FGF23 GJA1 KL
11 craniofacial MP:0005382 10.09 GJA1 KL LMNA RECQL4 TCOF1 WRN
12 muscle MP:0005369 9.87 CD44 ERCC6 GJA1 HBEGF KL LMNA
13 renal/urinary system MP:0005367 9.8 CD44 FERMT1 FGF23 KL LMNA TRPV5
14 skeleton MP:0005390 9.77 CD44 ERCC6 FBLIM1 FGF23 GJA1 HBEGF
15 respiratory system MP:0005388 9.76 CD44 FGF23 GJA1 HBEGF HYAL3 KL
16 vision/eye MP:0005391 9.23 CD44 ERCC6 GJA1 KL LMNA RECQL4

Drugs & Therapeutics for Skin Atrophy

Drugs for Skin Atrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 117)
# Name Status Phase Clinical Trials Cas Number PubChem Id
mometasone furoate Approved, Investigational, Vet_approved Phase 4 83919-23-7
Zinc Approved, Investigational Phase 4 7440-66-6 32051
Zinc oxide Approved Phase 4 1314-13-2
Coal tar Approved Phase 4 8007-45-2
Clobetasol Approved, Experimental, Investigational Phase 4 25122-41-2, 25122-46-7 32798 5311051
Petrolatum Approved, Investigational Phase 4 8009-03-8
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
10 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
14 Anti-Allergic Agents Phase 4
15 Pharmaceutical Solutions Phase 4
16 Clobetasone butyrate Phase 4
17 Hormones Phase 4
18 Hormone Antagonists Phase 4
19 glucocorticoids Phase 4
20 Emollients Phase 4
21 Anti-Inflammatory Agents Phase 4
22 Lidocaine, Prilocaine Drug Combination Phase 4
23 decanoic acid Phase 4
24 Protective Agents Phase 4
25 Vasoconstrictor Agents Phase 4
26 Halobetasol Phase 4
27 Gastrointestinal Agents Phase 4
28 Methylprednisolone Acetate Phase 4
29 Antineoplastic Agents, Hormonal Phase 4
30 Antiemetics Phase 4
31 Neuroprotective Agents Phase 4
32 retinol Phase 4
33 Retinol palmitate Phase 4
leucovorin Approved Phase 3 58-05-9 6006 143
Methotrexate Approved Phase 3 59-05-2, 1959-05-2 126941
Desonide Approved, Investigational Phase 3 638-94-8 5311066
Ketorolac Approved Phase 3 66635-83-4, 74103-06-3 3826
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
Dehydroepiandrosterone Approved, Investigational, Nutraceutical Phase 2, Phase 3 53-43-0 9860744
43 Dermatologic Agents Phase 3
44 Immunologic Factors Phase 3
45 Immunosuppressive Agents Phase 3
46 Antimetabolites Phase 3
47 Folic Acid Antagonists Phase 3
48 Vitamin B Complex Phase 3
49 Folate Phase 3
50 Vitamin B9 Phase 3

Interventional clinical trials:

(show all 47)
# Name Status NCT ID Phase Drugs
1 Comparison the Efficacy and Safety of 0.1% Tacrolimus Ointment With 0.1% Mometasone Furoate Cream in the Treatment of Adult Vitiligo: A Single Blinded Pilot Study Unknown status NCT01333410 Phase 4 tacrolimus ointment;Mometasone furoate
2 A Randomized Controlled Pilot Study Comparing the Efficacy of Topical Coal Tar to Topical Corticosteroids in Children Aged 1 to < 16 Years With Moderate-severe Atopic Dermatitis Unknown status NCT03461302 Phase 4 Topical coal tar;Topical corticosteroids
3 Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery Completed NCT02487212 Phase 4 0.05% Clobetasol propionate;Petrolatum gel
4 An Open-label Multicenter 12-month Long Term Study on Skin Reconstitution With Pimecrolimus Cream 1% in Adult Patients With Atopic Eczema and Corticosteroid Induced Skin Damage Completed NCT00367393 Phase 4 Pimecrolimus cream 1%
5 Comparison of Efficacy and Safety of Psoriatic Nails Treatment Between by Intralesional 0.1%Triamcinolone Injection and Topical 0.05%Clobetasol Propionate Ointment Completed NCT01703325 Phase 4 0.1% triamcinolone , 0.05% clobetasol propionate ointment
6 Pimecrolimus Cream 1% (Elidel®) and Medicated Device Cream (EletoneTM) in the Treatment and Maintenance of Atopic Dermatitis. Completed NCT01177566 Phase 4 pimecrolimus
7 A Randomized, Double-Blinded Study of Epiceram Versus Elidel in Pediatric Subjects With Mild to Moderate Atopic Dermatitis Completed NCT00460083 Phase 4 Elidel(R) (pimecrolimus 1%)
8 Bilateral Comparison Study of Elidel® (Pimecrolimus) Cream 1% and Hylatopic™ Plus Emollient Foam™ Emollient Foam in the Treatment of Subjects With Atopic Dermatitis Completed NCT01202149 Phase 4
9 A Randomized, Double-blind Study to Evaluate the Efficacy of Ammonium Lactate Lotion 12% (Lac-hydrin®) and Halobetasol Propionate Ointment 0.05% (Ultravate®) in the Treatment and Maintenance of Psoriasis. Completed NCT01111123 Phase 4 Lac-Hydrin lotion (ammonium lactate lotion 12%) ; UItravate ointment (halobetasol propionate ointment 0.05%);Lac-Hydrin lotion (ammonium lactate lotion 12%); placebo ointment
10 Local Steroid Injection vs Wrist Splinting for Carpal Tunnel Syndrome: A Randomized Clinical Trial Completed NCT02140632 Phase 4
11 Physiopathological Study and Pharmacological Modulation of Cutaneous Atrophy's Markers Induced by Glucocorticoids Unknown status NCT00709579 Phase 3 RV3391A;Placebo
12 Comparison of Monotherapy With Protracted Superpotent Topical Steroids to Superpotent Topical Steroids Associated With Methotrexate in Bullous Pemphigoid Unknown status NCT02313870 Phase 3 clobetasol propionate + Methotrexate;clobetasol propionate alone
13 A Randomized, Double-Blind, Active Control, 5 Week Study to Evaluate the Safety and Skin Effects of A New, Twice-daily, Topically Applied Amino Acid Moisturizing Cream vs. Desonide Cream in Adult Atopic Dermatitis Unknown status NCT02286700 Phase 3 Desonide Cream
14 Phase II-III Placebo-Controlled, Study to Evaluate the Effects of DHEA on Vasomotor Symptoms (Hot Flashes) in Postmenopausal Women Completed NCT00317148 Phase 2, Phase 3 Placebos;DHEA capsule
15 Effect of DHEA on Skin Aging - Placebo-Controlled and Randomized Phase III Study in Postmenopausal Women. Completed NCT00248989 Phase 3 Dehydroepiandrosterone;Placebos
16 A Clinical Trial on Topotect® (Dexrazoxane) in the Treatment of Accidental Extravasation of Anthracycline Anti-cancer Agents Completed NCT00548704 Phase 2, Phase 3 Dexrazoxane
17 Phase 2/Phase 3 of the Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis. Completed NCT00947765 Phase 2, Phase 3 Local corticosteroid injection
18 Efficacy of Topical Pimecrolimus in the Treatment of Pityriasis Alba: A Randomized Placebo-controlled Trial Not yet recruiting NCT03834935 Phase 2, Phase 3 Elidel (pimecrolimus 1%);Cold Cream
19 A Double-blinded, Prospective, Randomized, Controlled Trial Comparing Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders Terminated NCT02266433 Phase 3 Ketorolac;Dexamethasone
20 Novel Compositions for Treating or Preventing Dermal Disorders Unknown status NCT03103893 Phase 1, Phase 2 Rapamycin
21 Interest of Topical Spironolactone's Administration to Prevent Corticoid-induced Epidermal Atrophy Completed NCT01407471 Phase 2 Clobetasol + Spironolactone;Clobetasol + Placebo;Placebo + Spironolactone;Placebo + Placebo
22 A Randomized, Controlled, Observer-blind Psoriasis Plaque Test to Investigate the Anti-psoriatic Efficacy, Tolerability and Safety (Skin Atrophy) of LAS41004 Formulations in Patients With Mild to Moderate Plaque Psoriasis Completed NCT02111499 Phase 1, Phase 2 LAS41004-IMP1;LAS41004 IMP2;LAS41004 IMP3;LAS41004 IMP4;LAS41004 IMP6;LAS41004 IMP5
23 The Efficacy of Topical Tacrolimus in the Treatment of Cutaneous Lupus Erythematosus - a Multi-Center-Trial Completed NCT00317681 Phase 2 Tacrolimus ointment
24 Efficacy and Safety of Topical Indigo Naturalis in Treating Atopic Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Trial Completed NCT02669888 Phase 2 Indigo naturalis ointment;Placebo
25 A 6-week Randomized, Double-blind, Vehicle-controlled Pilot Study With a 6-week Open Label Extension to Assess the Efficacy and Safety of Pimecrolimus 1% Cream in the Treatment of Oral Lichen Planus Completed NCT00297037 Phase 2 Pimecrolimus 1% cream
26 A Double-Blind, Parallel-group Trial of Topical Pimecrolimus Cream 1% (Elidel®) Versus Clobetasol 0.05% Cream for the Treatment of Vulvar Lichen Sclerosus Completed NCT00393263 Phase 2 pimecrolimus and clobetasol;clobetasol 0.05% cream
27 Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valerate 0.1% Cream on Skin Structure and Function in Participants With Atopic Dermatitis. Not yet recruiting NCT04194814 Phase 2 crisaborole (2%) ointment;betamethasone valerate 0.1% cream
28 A Randomized, Placebo-controlled Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of Subcutaneous Dupilumab in Localized Scleroderma Not yet recruiting NCT04200755 Phase 2 Dupilumab 300Mg Solution for Injection
29 A Single-Centre, Explorative, Randomised, Investigator-Blinded, Negative-Controlled, Phase I Clinical Trial With Intra-Individual Comparison of Treatments to Assess Steroid Induced Skin Atrophy on Healthy Skin Completed NCT02355639 Phase 1 Clobetasol propionate 0.05 % ointment;Betamethasone dipropionate 0.064 % ointment;Petrolatum ointment
30 A Prospective, Randomised, Investigator-Blinded, Vehicle-Controlled, Phase I Clinical Trial With Intra-Individual Comparison of Treatments to Assess the Potential of LEO 130852A Gel to Reduce Steroid Induced Skin Atrophy on Healthy Skin Completed NCT02392130 Phase 1 Clobetasol propionate 0.05% ointment;LEO 130852A gel 1%;LEO 130852A placebo gel
31 A Phase I, Single-Center, Randomized, Vehicle and Active-Controlled Study to Assess and Compare the Atrophy-Causing Potential of Topical CRx-191 Formulations in Healthy Volunteers Completed NCT00544687 Phase 1 CRx-191;mometasone furoate;nortriptyline HCl;Karison® Creme;Vehicle
32 DHEA Bioavailability Following Administration of Vaginal Suppositories in Post-Menopausal Women With Vaginal Atrophy-Phase I Randomized,Placebo-Controlled, Double-Blind Study. Completed NCT00429806 Phase 1 DHEA;Placebo
33 A Randomised, Double-blind (for GW870086), Placebo-controlled Study of Topical GW870086 Formulation to Explore the Potential for Skin Thinning in Healthy Adult Volunteers Completed NCT01381445 Phase 1 GW870086 0.2%;GW870086 2%;Clobetasol Propionate;Placebo
34 An Open, Uncontrolled Pharmacokinetic Study With a New Topical Combination Gel Containing Triiodothyroacetic Acid (TRIAC) and Dehydroepiandrosterone (DHEA) in Subjects With Skin Atrophy Due to Topical Treatment With Glucocorticoids Not yet recruiting NCT03783988 Phase 1
35 Treatment of Atrophic Acne Scars With a Fractional CO2 Laser at 1 Versus 3 Months Intervals. A Randomized Controlled Trial With Blinded Response Evaluations Unknown status NCT01773343
36 Treatment of Nonneoplastic Epithelial Disorders of Skin and Mucosa of Vulva With High Intensity Focused Ultrasound Unknown status NCT02890277 Fu Tiankang disposable vaginal filling suppository, Albothyl (Policresulen Solution) , and the gynecologic medical antimicrobial dressing gel (chitosan gel).
37 The Comparison Study of Intralesional Botulinum Toxin A and Corticosteroid Injection for Alopecia Areata Unknown status NCT00999869 Botulinum toxin type A;Triamcinolone acetonide
38 Eosinophilic Granulomatosis With Polyangiitis Cohort Unknown status NCT03036670
39 A Randomised Controlled Trial Assessing the Efficacy of Targeted Intervention for Topical Steroid Phobia. Completed NCT03658252
40 Single Blind Study to Evaluate the Tolerance and Effectiveness of Redermic Versus Rejuva-A™ (0.025% Tretinoin) and Redermic in Combination With Rejuva-A™ (0.025% Tretinoin) Under Normal Conditions in Subjects With Signs of Aging Completed NCT00974480 Tretinoin (Rejuva-A)
41 A Prospective, Randomized, Split-Arm Pilot Study Investigating the Efficacy and Safety of Sciton's Broad Band Light With and Without Cutera's Radiofrequency Microneedling for Improving the Clinical Signs of Senile Purpura Completed NCT03690375
42 Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain: A Randomized Double Blinded Control Trial Recruiting NCT04128605
43 Pathogenesis of Focal Dermal Hypoplasia or Goltz Syndrome and Related Disorders Active, not recruiting NCT00691223
44 A Double Blinded Sham Controlled Trial of Fractional CO2 Laser Treatment Using the DEKA SmartXide Touch Laser System (MonaLisa Touch) for the Treatment of Vulvar Lichen Sclerosus Active, not recruiting NCT03665584
45 Efficacy of Dextrose Injections, Corticosteroids Injections and Surgical Release for Treatment of the Carpal Tunnel Syndrome: a Prospective, Randomized, Double-blind Controlled Trial Not yet recruiting NCT04014244 Corticosteroid vs. Dextrose
46 Evaluation of the Therapeutic Effect and Local Tolerability of Elidel® Cream 1% (Pimecrolimus) in Chronic Discoid Lupus Erythematosus (dLE) or Subacute Cutaneous Lupus Erythematosus (scLE) Withdrawn NCT00222183 Elidel (pimecrolimus)
47 Use of Topical Euphrasia, a Homeopathic Remedy in Ophthalmology Withdrawn NCT02416128 Euphrasia;Prednisolone acetate

Search NIH Clinical Center for Skin Atrophy

Genetic Tests for Skin Atrophy

Anatomical Context for Skin Atrophy

MalaCards organs/tissues related to Skin Atrophy:

Skin, Testes, Liver, Breast, Bone, Thyroid, Tongue

Publications for Skin Atrophy

Articles related to Skin Atrophy:

(show top 50) (show all 864)
# Title Authors PMID Year
Erosive pustular dermatosis of the scalp: causes and treatments. 61
32516510 2020
Multiple subcutaneous haematomas of the legs causing skin necrosis in an elderly patient affected by corticosteroid-induced skin atrophy: Case report and review of literature. 61
31972900 2020
Pharmacological management of atopic dermatitis in the elderly. 61
32100586 2020
Efficacy and safety of verapamil vs triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. 61
32400925 2020
Preclinical study of the topical anti-inflammatory activity of Cyperus rotundus L. extract (Cyperaceae) in models of skin inflammation. 61
32109543 2020
The Safety and Efficacy of Intralesional Verapamil Versus Intralesional Triamcinolone Acetonide for Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis. 61
32195728 2020
Corticoid-like anti-inflammatory effect of Vochysia bifalcata Warm.: Preclinical evidence of efficacy and safety. 61
31836516 2020
Linear Atrophoderma of Moulin. 61
32236506 2020
A novel pathogenic FERMT1 variant in four families with Kindler syndrome in Argentina. 61
31957900 2020
Long-term safety and efficacy of delgocitinib ointment, a topical Janus kinase inhibitor, in adult patients with atopic dermatitis. 61
31820485 2020
Acute Radiation Therapy-related Dermatitis. 61
32155122 2020
Dermoscopy of idiopathic atrophoderma of Pasini and Pierini. 61
31424083 2020
Linear atrophoderma of Moulin: dermal or subcutaneous atrophy? 61
32100290 2020
A case of linear atrophoderma of Moulin. 61
31899064 2020
Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin. 61
32064044 2020
[Fatal outcome of Netherton syndrome due to excessive use of topical corticosteroids in an adult patient]. 61
31653452 2020
Black tea dressings - a rapidly effective treatment for facial dermatitis. 61
30668184 2019
Two-years of home based functional electrical stimulation recovers epidermis from atrophy and flattening after years of complete Conus-Cauda Syndrome. 61
31876739 2019
Functional outcome of De Quervain's tenosynovitis with longitudinal incision in surgically treated patients. 61
30600438 2019
Successful treatment with oral minocycline in a case with a long-standing idiopathic atrophoderma of Pasini and Pierini: Histopathological comparison with the contralateral normal skin. 61
31463968 2019
Changes in Dermal Thickness in Biopsy Study of Histologic Findings After a Single Injection of Polycaprolactone-Based Filler into the Dermis. 61
30778526 2019
Bilateral Facial Apocrine Fibrosing Hamartoma Mimicking Microcystic Adnexal Carcinoma. 61
31045870 2019
Real-world safety evaluation of topical corticosteroid use: A community pharmacy-based, prospective, observational study. 61
30983117 2019
Clinical Efficacy of Oligofructans from Ophiopogon japonicus in Reducing Atopic Dermatitis Flare-ups in Caucasian Patients. 61
31120541 2019
Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling. 61
31518356 2019
Platinum and palladium nanoparticle-containing mixture, PAPLAL, does not induce palladium allergy. 61
31260134 2019
New features of aplasia cutis congenita type 5 - Skin atrophy associated with respiratory insufficiency and multiple intestinal atresia caused by the early death of twin fetus. 61
30316734 2019
Linear cutaneous hypopigmentation and atrophy associated with intralesional steroid injection: A rarely described adverse reaction. 61
31012196 2019
Assessment of the risk and characterization of non-melanoma skin cancer in Kindler syndrome: study of a series of 91 patients. 61
31340837 2019
The glucocorticoid receptor agonistic modulators CpdX and CpdX-D3 do not generate the debilitating effects of synthetic glucocorticoids. 61
31221758 2019
Amino acid substitution in the C-terminal domain of collagen XVII reduces laminin-332 interaction causing mild skin fragility with atrophic scarring. 61
30316981 2019
A phase 2, multicenter, double-blind, randomized, vehicle-controlled clinical study to compare the safety and efficacy of a halobetasol propionate 0.01% lotion and halobetasol propionate 0.05% cream in the treatment of plaque psoriasis. 61
30207807 2019
The knowledge of issues associated with topical corticosteroids using in patients with atopic dermatitis. 61
31260432 2019
The role of personalized Interventional Radiotherapy (brachytherapy) in the management of older patients with non-melanoma skin cancer. 61
30314955 2019
Linear atrophoderma of Moulin and atrophoderma of Pasini and Pierini. The relevance of ultrasound imaging in the initial assessment. 61
31104466 2019
Collagen I Promotes Adipocytogenesis in Adipose-Derived Stem Cells In Vitro. 61
30939867 2019
Hypocellular medallion-like dermal dendrocyte hamartoma on the abdomen of a 25 year old male. 61
30635930 2019
Barber Say Syndrome (A New Case Report). 61
30984591 2019
Erosive Pustular Dermatosis of the Leg Successfully Treated With an Oral Retinoid and a Bi-layered Skin Substitute 61
30909353 2019
PI3K inhibitors protect against glucocorticoid-induced skin atrophy. 61
30737086 2019
Syringaresinol Reverses Age-Related Skin Atrophy by Suppressing FoxO3a-Mediated Matrix Metalloproteinase-2 Activation in Copper/Zinc Superoxide Dismutase-Deficient Mice. 61
30798853 2019
Atrophoderma of Pasini and Pierini in a young adult: a case report. 61
30901070 2019
Atrophoderma of Pasini and Pierini in a patient with concomitant psoriasis: Response to methotrexate. 61
30891480 2019
Retraction note: Inflamed bilateral linear atrophoderma of Moulin in an adult woman: a case report 61
30968684 2019
Idiopathic Atrophoderma of Pasini and Pierini: Case report and literature review. 61
30847185 2019
Microfocused Ultrasound with Visualization for the Treatment of Stretch Marks. 61
30881579 2019
Sclareol attenuates the development of atopic dermatitis induced by 2,4-dinitrochlorobenzene in mice. 61
30704333 2019
[Keratosis pilaris]. 61
31692799 2019
The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition. 61
30332502 2019
Treatment of keloid scars with intralesional triamcinolone and 5-fluorouracil injections - a randomized controlled trial. 61
30448246 2019

Variations for Skin Atrophy

Expression for Skin Atrophy

Search GEO for disease gene expression data for Skin Atrophy.

Pathways for Skin Atrophy

Pathways related to Skin Atrophy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
2 11.59 GJA1 FERMT1 CD44
3 11.31 HBEGF GJA1 CD44
4 10.95 TRPV5 KL HBEGF FGF23
5 10.92 MMP1 HBEGF CD44

GO Terms for Skin Atrophy

Biological processes related to Skin Atrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA duplex unwinding GO:0032508 9.43 WRN RECQL4 ERCC6
2 nuclear envelope organization GO:0006998 9.4 ZMPSTE24 LMNA
3 hyaluronan catabolic process GO:0030214 9.37 HYAL3 CD44
4 DNA unwinding involved in DNA replication GO:0006268 9.32 WRN RECQL4
5 cellular response to parathyroid hormone stimulus GO:0071374 9.16 GJA1 FGF23
6 telomeric D-loop disassembly GO:0061820 8.96 WRN RECQL4
7 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway GO:0090080 8.62 KL FGF23

Molecular functions related to Skin Atrophy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.39 ZMPSTE24 WRN TRPV5 TCOF1 RECQL4 MBTPS2
2 hydrolase activity GO:0016787 9.76 ZMPSTE24 WRN RECQL4 MMP1 MBTPS2 KL
3 metalloendopeptidase activity GO:0004222 9.61 ZMPSTE24 MMP1 MBTPS2
4 DNA helicase activity GO:0003678 9.43 WRN RECQL4 ERCC6
5 3'-5' DNA helicase activity GO:0043138 9.4 WRN RECQL4
6 structural constituent of epidermis GO:0030280 9.37 LORICRIN FLG
7 bubble DNA binding GO:0000405 9.32 WRN RECQL4
8 four-way junction helicase activity GO:0009378 8.96 WRN RECQL4
9 telomeric D-loop binding GO:0061821 8.62 WRN RECQL4

Sources for Skin Atrophy

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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