MCID: SKN002
MIFTS: 27

Skin Lipoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Skin Lipoma

MalaCards integrated aliases for Skin Lipoma:

Name: Skin Lipoma 12 15
Lipoma of Skin 12 73
Cutaneous Lipomatous Neoplasm 73
Cutaneous Lipomatous Tumor 12
Cutaneous Lipoma 12
Lipoma of Face 12

Classifications:



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Disease Ontology 12 DOID:10188
ICD9CM 35 214.0
NCIt 50 C4616 C5566
SNOMED-CT 68 93159009

Summaries for Skin Lipoma

Disease Ontology : 12 A lipoma that is located in the skin.

MalaCards based summary : Skin Lipoma, also known as lipoma of skin, is related to cleft, median, of upper lip with polyps of facial skin and nasal mucosa and facial hemiatrophy. An important gene associated with Skin Lipoma is ARHGEF1 (Rho Guanine Nucleotide Exchange Factor 1), and among its related pathways/superpathways are Pathways in cancer and EGF/EGFR Signaling Pathway. Affiliated tissues include skin, heart and tongue, and related phenotypes are adipose tissue and cardiovascular system

Related Diseases for Skin Lipoma

Diseases related to Skin Lipoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cleft, median, of upper lip with polyps of facial skin and nasal mucosa 11.1
2 facial hemiatrophy 9.9 HMGA2 ARHGEF1
3 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.9 PTEN HMGA2
4 lipomatosis, multiple 9.9 PTEN HMGA2
5 lipomatosis 9.8 PTEN HMGA2
6 cowden syndrome 1 9.8
7 ruvalcaba syndrome 9.8
8 breast adenocarcinoma 9.8 PTEN HMGA2

Graphical network of the top 20 diseases related to Skin Lipoma:



Diseases related to Skin Lipoma

Symptoms & Phenotypes for Skin Lipoma

MGI Mouse Phenotypes related to Skin Lipoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 adipose tissue MP:0005375 9.33 APPL1 LDLR PTEN
2 cardiovascular system MP:0005385 9.26 APPL1 ARHGEF1 LDLR PTEN
3 muscle MP:0005369 8.92 APPL1 ARHGEF1 LDLR PTEN

Drugs & Therapeutics for Skin Lipoma

Search Clinical Trials , NIH Clinical Center for Skin Lipoma

Genetic Tests for Skin Lipoma

Anatomical Context for Skin Lipoma

MalaCards organs/tissues related to Skin Lipoma:

41
Skin, Heart, Tongue

The Foundational Model of Anatomy Ontology organs/tissues related to Skin Lipoma:

19
The Skin

Publications for Skin Lipoma

Articles related to Skin Lipoma:

# Title Authors Year
1
Cutaneous lipoma in children: 5 cases with Bannayan-Riley-Ruvalcaba syndrome. ( 16952599 )
2006

Variations for Skin Lipoma

Expression for Skin Lipoma

Search GEO for disease gene expression data for Skin Lipoma.

Pathways for Skin Lipoma

Pathways related to Skin Lipoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.85 APPL1 ARHGEF1 PTEN
2 11.47 ARHGEF1 PTEN
3 11.22 LDLR PTEN
4 10.13 APPL1 LDLR

GO Terms for Skin Lipoma

Biological processes related to Skin Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.33 HMGA2 LDLR PTEN
2 cell proliferation GO:0008283 9.13 APPL1 ARHGEF1 PTEN
3 positive regulation of apoptotic process GO:0043065 8.8 ARHGEF1 HMGA2 PTEN

Molecular functions related to Skin Lipoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 APPL1 LDLR PTEN

Sources for Skin Lipoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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