MCID: SKN011
MIFTS: 27

Skin Pilomatrix Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Skin Pilomatrix Carcinoma

MalaCards integrated aliases for Skin Pilomatrix Carcinoma:

Name: Skin Pilomatrix Carcinoma 12 15
Pilomatrix Carcinoma of Skin 12 74
Pilomatricoma, Malignant 12
Malignant Pilomatricoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5376
NCIt 51 C4114
SNOMED-CT 69 24762001
UMLS 74 C0585475

Summaries for Skin Pilomatrix Carcinoma

MalaCards based summary : Skin Pilomatrix Carcinoma, also known as pilomatrix carcinoma of skin, is related to pilomatrix carcinoma and pilomatrixoma. An important gene associated with Skin Pilomatrix Carcinoma is KRT31 (Keratin 31), and among its related pathways/superpathways are DNA Damage Response (only ATM dependent) and Glioblastoma Multiforme. Affiliated tissues include skin and bone.

Wikipedia : 77 Malignant pilomatricoma (also known as a "Pilomatrical carcinoma," and "Pilomatrix carcinoma") is a... more...

Related Diseases for Skin Pilomatrix Carcinoma

Diseases related to Skin Pilomatrix Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 pilomatrix carcinoma 11.3
2 pilomatrixoma 10.5
3 hair follicle neoplasm 9.7 CTNNB1 HOXC13

Symptoms & Phenotypes for Skin Pilomatrix Carcinoma

Drugs & Therapeutics for Skin Pilomatrix Carcinoma

Search Clinical Trials , NIH Clinical Center for Skin Pilomatrix Carcinoma

Genetic Tests for Skin Pilomatrix Carcinoma

Anatomical Context for Skin Pilomatrix Carcinoma

MalaCards organs/tissues related to Skin Pilomatrix Carcinoma:

42
Skin, Bone

Publications for Skin Pilomatrix Carcinoma

Articles related to Skin Pilomatrix Carcinoma:

(show all 17)
# Title Authors Year
1
Malignant pilomatricoma of the cheek in an infant. ( 30613091 )
2018
2
Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. ( 28795016 )
2017
3
Malignant Pilomatricoma: A Report of Two Cases and Review of Literature. ( 28892916 )
2017
4
Malignant pilomatricoma: two new observations and review of the relevant literature. ( 24448707 )
2014
5
Malignant pilomatricoma with multiple bone metastases in a dog: Histological and immunohistochemical study. ( 23596465 )
2013
6
Malignant pilomatricoma in a dog. ( 22520811 )
2012
7
Malignant pilomatricoma in a soft-coated Wheaten Terrier. ( 19886971 )
2010
8
Malignant pilomatricoma in 3 dogs. ( 20466858 )
2010
9
Malignant pilomatricoma in the upper eyelid. ( 21686824 )
2009
10
Malignant pilomatricoma in a child with a previous vascular malformation. ( 17884262 )
2008
11
Malignant pilomatricoma in the parietal area. ( 17189991 )
2006
12
Inverted malignant pilomatricoma of the neck. ( 15258812 )
2005
13
Malignant pilomatricoma. ( 12038205 )
2002
14
Malignant pilomatricoma: a case report. ( 9679696 )
1998
15
Malignant pilomatricoma. An immunohistochemical study with antihair keratin antibody. ( 1370134 )
1992
16
Malignant pilomatricoma. ( 6721545 )
1984
17
Malignant pilomatricoma in a dog. ( 7334160 )
1981

Variations for Skin Pilomatrix Carcinoma

Expression for Skin Pilomatrix Carcinoma

Search GEO for disease gene expression data for Skin Pilomatrix Carcinoma.

Pathways for Skin Pilomatrix Carcinoma

GO Terms for Skin Pilomatrix Carcinoma

Cellular components related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein-DNA complex GO:0032993 8.96 CTNNB1 LEF1
2 beta-catenin-TCF complex GO:1990907 8.62 CTNNB1 LEF1

Biological processes related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anatomical structure morphogenesis GO:0009653 9.48 HOXC13 KRT35
2 cornification GO:0070268 9.46 KRT31 KRT35
3 canonical Wnt signaling pathway GO:0060070 9.43 CTNNB1 LEF1
4 odontogenesis of dentin-containing tooth GO:0042475 9.4 CTNNB1 LEF1
5 positive regulation of epithelial to mesenchymal transition GO:0010718 9.37 CTNNB1 LEF1
6 epithelial to mesenchymal transition GO:0001837 9.32 CTNNB1 LEF1
7 Wnt signaling pathway, calcium modulating pathway GO:0007223 9.26 CTNNB1 LEF1
8 beta-catenin-TCF complex assembly GO:1904837 9.16 CTNNB1 LEF1
9 branching involved in blood vessel morphogenesis GO:0001569 8.96 CTNNB1 LEF1
10 vasculature development GO:0001944 8.62 CTNNB1 LEF1

Molecular functions related to Skin Pilomatrix Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.13 CTNNB1 HOXC13 LEF1
2 estrogen receptor binding GO:0030331 8.62 CTNNB1 LEF1

Sources for Skin Pilomatrix Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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