Skin Sarcoidosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: SKN006 MIFTS: 40	Skin Sarcoidosis Categories: Immune diseases, Skin diseases
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Aliases & Classifications for Skin Sarcoidosis

MalaCards integrated aliases for Skin Sarcoidosis:

Name: Skin Sarcoidosis ¹² ¹⁵

Cutaneous Sarcoidosis ¹² ⁷³

Cutaneous Sarcoid ¹²

Classifications:

MalaCards categories:
Anatomical: Immune diseases Skin diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Certain disorders involving the immune mechanism

Sarcoidosis

Sarcoidosis of skin

External Ids:

Disease Ontology ¹² DOID:13402

ICD10 ³³ D86.3

NCIt ⁵⁰ C34996

SNOMED-CT ⁶⁸ 187234008 55941000

UMLS ⁷³ C0036203

Sources

Summaries for Skin Sarcoidosis

MalaCards based summary : Skin Sarcoidosis, also known as cutaneous sarcoidosis, is related to blau syndrome and granulomatous hepatitis. An important gene associated with Skin Sarcoidosis is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are NF-kappaB Signaling and TNF signaling pathway. The drugs Apremilast and beta-endorphin have been mentioned in the context of this disorder. Affiliated tissues include skin and thyroid, and related phenotypes are cardiovascular system and endocrine/exocrine gland

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Related Diseases for Skin Sarcoidosis

Diseases related to Skin Sarcoidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)

#	Related Disease	Score	Top Affiliating Genes
1	blau syndrome	11.0
2	granulomatous hepatitis	10.4	ACE TNFRSF1B
3	subacute cutaneous lupus erythematosus	10.4	ACE TNF
4	granulomatous dermatitis	10.4	ACE TNF
5	posterior urethral valves	10.4	ACE TNF
6	ischemic heart disease	10.4	ACE TNF
7	systolic heart failure	10.3	ACE TNF
8	rheumatoid lung disease	10.3	TNF TNFRSF1B
9	extrinsic cardiomyopathy	10.3	ACE TNF
10	chronic gonococcal salpingitis	10.3	TNF TNFRSF1B
11	scleral disease	10.3	TNF TNFRSF1B
12	pustulosis of palm and sole	10.3	TNF TNFRSF1B
13	peroneal neuropathy	10.3	TNF TNFRSF1B
14	rheumatic heart disease	10.3	ACE TNF
15	periodic fever, familial, autosomal dominant	10.3	TNF TNFRSF1B
16	sweat gland disease	10.3	TNF TNFRSF1B
17	pyelonephritis	10.3	ACE TNF
18	limb ischemia	10.3	ACE TNF
19	acute salpingitis	10.3	TNF TNFRSF1B
20	post-transplant lymphoproliferative disease	10.3	TNF TNFRSF1B
21	chronic salpingitis	10.3	TNF TNFRSF1B
22	silicosis	10.3	ACE TNF
23	panuveitis	10.3	TNF TNFRSF1B
24	adult respiratory distress syndrome	10.3	ACE TNF
25	palindromic rheumatism	10.3	TNF TNFRSF1B
26	pulmonary edema	10.3	ACE TNF
27	carotid stenosis	10.3	ACE TNF
28	exanthem	10.3	TNF TNFRSF1B
29	cogan syndrome	10.3	TNF TNFRSF1B
30	pulmonary sarcoidosis	10.3	ACE TNF
31	guillain-barre syndrome	10.2	TNF TNFRSF1B
32	hypersensitivity reaction disease	10.2	ACE TNF
33	spondyloarthropathy 1	10.2	TNF TNFRSF1B
34	sleep apnea	10.2	ACE TNF
35	eales disease	10.2	SERPINF1 TNF
36	primary bacterial infectious disease	10.2	TNF TNFRSF1B
37	bone inflammation disease	10.2	TNF TNFRSF1B
38	end stage renal failure	10.2	ACE TNF
39	intestinal disease	10.2	TNF TNFRSF1B
40	vascular dementia	10.2	ACE TNF
41	microvascular complications of diabetes 5	10.2	ACE SERPINF1
42	spondylitis	10.1	TNF TNFRSF1B
43	juvenile rheumatoid arthritis	10.1	TNF TNFRSF1B
44	glucose metabolism disease	10.1	ACE TNF
45	urinary system disease	10.1	ACE TNF
46	arteries, anomalies of	10.1	ACE TNF
47	otosclerosis	10.1	ACE SERPINF1
48	immune system disease	10.0	ACE TNF
49	membranous nephropathy	10.0	ACE TNF
50	chagas disease	10.0	ACE TNF

Graphical network of the top 20 diseases related to Skin Sarcoidosis:

Sources

Symptoms & Phenotypes for Skin Sarcoidosis

MGI Mouse Phenotypes related to Skin Sarcoidosis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	9.77	TNF TNFRSF1B ACE CD83 SERPINF1
2	endocrine/exocrine gland	MP:0005379	9.72	TNF TNFRSF1B ACE CD83 SERPINF1
3	hematopoietic system	MP:0005397	9.65	SERPINF1 TNF TNFRSF1B ACE CD83
4	immune system	MP:0005387	9.55	SERPINF1 TNF TNFRSF1B ACE CD83
5	liver/biliary system	MP:0005370	9.26	TNF TNFRSF1B ACE ADK
6	vision/eye	MP:0005391	8.92	SERPINF1 TNF TNFRSF1B ADK

Sources

Drugs & Therapeutics for Skin Sarcoidosis

Drugs for Skin Sarcoidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Apremilast

Approved, Investigational

Phase 2, Phase 3

608141-41-9

11561674

Synonyms:

Apremilast

Aprémilast

Apremilast (USAN)

Apremilastum

CC-10004

CHEBI:558773

CHEMBL514800

CID11561674

D08860

N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide

N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide

beta-endorphin

Phase 2, Phase 3

Adrenocorticotropic Hormone

Phase 2, Phase 3

Neurotransmitter Agents

Phase 2, Phase 3

Hormone Antagonists

Phase 2, Phase 3

Hormones

Phase 2, Phase 3

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 2, Phase 3

Endorphins

Phase 2, Phase 3

Melanocyte-Stimulating Hormones

Phase 2, Phase 3

Analgesics

Phase 2, Phase 3

Analgesics, Non-Narcotic

Phase 2, Phase 3

Angiogenesis Inhibitors

Phase 2, Phase 3,Phase 3

Angiogenesis Modulating Agents

Phase 2, Phase 3,Phase 3

Peripheral Nervous System Agents

Phase 2, Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3,Phase 3,Phase 1

Immunosuppressive Agents

Phase 2, Phase 3,Phase 3

Anti-Infective Agents

Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable

Anti-Inflammatory Agents

Phase 2, Phase 3

Anti-Inflammatory Agents, Non-Steroidal

Phase 2, Phase 3

Antirheumatic Agents

Phase 2, Phase 3

Rifampicin

Approved

Phase 1, Phase 2

13292-46-1

5458213 5381226

Synonyms:

13292-46-1

1-b]furan-21-yl acetate

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV

3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV

3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin

46713_FLUKA

46713_RIEDEL

62534-43-4

8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

8-(4-Methylpiperazinyliminomethyl) rifamycin SV

8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin

8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv

8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv

83907_FLUKA

83907_SIGMA

8CI)

Abrifam

Archidyn

Arficin

Arzide

AZT + Rifampin

Ba 41166

Ba 41166/E

BA-41166E

Benemicin

Benemycin

BIDD:PXR0014

Bio-0621

BPBio1_000561

BSPBio_000509

C06688

C43H58N4O12

CAS-13292-46-1

CCRIS 551

CHEBI:28077

CHEBI:455936

CHEMBL180

CID5381226

CID5388984

CID5458213

CID5702112

CID6604339

CID6708473

CID6842115

CID6912767

CID6913622

CPD001906767

D00211

DB01045

Dione 21-acetate

Dipicin

DivK1c_000550

Doloresum

DRG-0109

EINECS 236-312-0

Eremfat

Famcin

Fenampicin

HMS1569J11

HMS1920P08

HMS2089F12

HMS2092G09

HMS501L12

HSDB 3181

KBio1_000550

KBio2_000919

KBio2_003487

KBio2_006055

KBio3_003018

KBioGR_001780

KBioSS_000919

L-5103

L-5103 Lepetit

LS-7689

MLS000028552

MLS001148237

MLS001333745

MolPort-000-767-051

MolPort-002-513-586

MolPort-003-666-281

MolPort-006-395-891

NCGC00016699-01

NCGC00017365-01

NCGC00018178-01

NCGC00022678-03

NCGC00022678-04

NCGC00022678-05

NCGC00160500-01

nchembio884-comp4

NCI60_000309

NINDS_000550

NSC 113926

NSC113926

NSC-113926

Piperine & Rifampicin

Prestwick_833

Prestwick0_000525

Prestwick1_000525

Prestwick2_000525

Prestwick3_000525

R/AMP

R0079

R3501_SIAL

R3501_SIGMA

R5777_SIGMA

R7382_SIGMA

Ramp

RAMP

R-Cin

Reserpine & Rifampicin

Rfamipicin

RFP

Rifa

Rifadin

Rifadin (TN)

Rifadin I.V

Rifadin I.V.

Rifadin Iv

Rifadin IV

Rifadin, Rimactane, Rifampicin, Rifampin

Rifadine

Rifagen

Rifaldazin

Rifaldazine

Rifaldin

Rifam

Rifamicin AMP

Rifamor

Rifampicin

Rifampicin & EEP

Rifampicin & Propolis

Rifampicin (JP15/INN)

Rifampicin [INN:BAN:JAN]

Rifampicin SV

Rifampicina

Rifampicina [INN-Spanish]

Rifampicine

Rifampicine [French]

Rifampicinum

Rifampicinum [INN-Latin]

rifampin

Rifampin

Rifampin (USP)

Rifampin [USAN]

Rifamsolin

Rifamycin

Rifamycin Amp

Rifamycin AMP

Rifaprodin

Rifcin

Rifinah

Rifobac

Rifoldin

Rifoldine

Riforal

Rimactan

Rimactane

Rimactane (TN)

Rimactazid

Rimactin

Rimactizid

Rimazid

Rimycin

RMP

Rofact

S1764_Selleck

SAM002264646

Sinerdol

SMR000058322

SMR000653525

SPBio_002430

Spectrum_000439

SPECTRUM1500529

Spectrum3_001837

Spectrum4_001250

Spectrum5_002018

STK080143

TNP00313

Tubocin

UNII-VJT6J7R4TR

WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1

Azithromycin

Approved

Phase 1, Phase 2

83905-01-5

55185 447043

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Ethambutol

Approved

Phase 1, Phase 2

74-55-5

3279 14052

Synonyms:

(-)-(R,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-(S,S)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-2,2'-(ethylenediimino)Di-1-butanol

(+)-2,2'-(Ethylenediimino)di-1-butanol

(+)-ethambutol

(+)-Ethambutol

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-N,N'-Bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-S,S-ethambutol

(+)-S,S-Ethambutol

(2R)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2'S)-2,2'-[Ethane-1,2-diyldi(imino)]dibutan-1-ol

(2S)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2S)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

(2S,7S)-2,7-Diethyl-3,6-diazaoctane-1,8-diol

(R)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol

(S,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(S,S)-ethambutol

(S,S)-Ethambutol

1070-11-7

2,2'-(1,2-Ethylenediimino)-di-1-butanol

2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

74-55-5

75343-56-5

AC1L1FKQ

AC1L230T

AC1L9YT2

AC1LABPH

AC1LAKIP

AC1LAKIS

AC1Q2C85

AC1Q2SHV

AC1Q77PZ

Aethambutolum

AHP brand OF ethambutol hydrochloride

AR-1A7805

AR-1C2065

BPBio1_000105

BSPBio_000095

BSPBio_002012

C06984

C10H24N2O2

CAS-1070-11-7

CHEBI:4877

CHEMBL43824

CHEMBL44884

CID14052

CID3279

CID465436

CID470071

CID470072

CID504259

CL 40881 (dihydrochloride)

CPD000046147

d,N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

D07925

D-2,2'-(Ethylenediimino)bis(1-butanol)

D-2,2'-(Ethylenediimino)di-1-butanol

Dadibutol

DB00330

D-Ethambutol

Dexambutol

Diambutol

DivK1c_000561

D-N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

EINECS 200-810-6

Elan brand OF ethambutol hydrochloride

EMB

EMB fatol

EMB hefa

EMB-fatol

EMB-hefa

Etambutol

Etambutol [INN-Spanish]

Etambutol llorente

Etambutolo

Etambutolo [DCIT]

ethambutol

Ethambutol

Ethambutol & EEP

Ethambutol & Propolis

Ethambutol (INN)

Ethambutol [INN:BAN]

Ethambutol dihydrochloride

Ethambutol HCL

Ethambutol hydrochloride

Ethambutol Hydrochloride

Ethambutol, (-)-isomer

Ethambutol, meso form

Ethambutol, racemic mixture

Ethambutolum

Ethambutolum [INN-Latin]

Etibi

Fatol brand OF ethambutol hydrochloride

Genopharm brand OF ethambutol hydrochloride

HSDB 3078

Hydrochloride, ethambutol

ICN brand OF ethambutol hydrochloride

IDI1_000561

KBio1_000561

KBio2_001538

KBio2_004106

KBio2_006674

KBio3_001232

KBioGR_001209

KBioSS_001538

KST-1A8084

Lederle brand OF ethambutol hydrochloride

Llorente brand OF ethambutol hydrochloride

Llorente, etambutol

LS-187119

LS-46537

Miambutol

MLS000082702

MolPort-002-507-956

MolPort-003-847-110

Myambutol

Myambutol (dihydrochloride)

NCGC00016560-01

NCGC00178864-01

NCGC00179661-01

NINDS_000561

NSC653313

Prestwick0_000028

Prestwick1_000028

Prestwick2_000028

Prestwick3_000028

Purderal

Riemser brand OF ethambutol hydrochloride

S,S-Ethambutol

SAM002589988

Sanavita brand OF ethambutol hydrochloride

SERB brand OF ethambutol hydrochloride

Servambutol

Servambutol (TN)

SMR000046147

SPBio_001167

SPBio_002016

Spectrum_001058

Spectrum2_001014

Spectrum3_000426

Spectrum4_000545

Spectrum5_000702

STK711105

STOCK5S-98432

Tibutol

UNII-8G167061QZ

Wernigerode brand OF ethambutol hydrochloride

Wyeth brand OF ethambutol hydrochloride

Ofloxacin

Approved

Phase 1, Phase 2

82419-36-1

4583

Synonyms:

( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure

(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

(+/-)-Floxin

118120-51-7 (hydrochloride)

33703_FLUKA

33703_RIEDEL

82419-36-1

83380-47-6

85344-55-4

8-fluoro-3-Methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylate

8-fluoro-3-Methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

AB00513820

AC1L1IHM

AC-7616

AKOS001033517

Bactocin

BB_SC-1252

BPBio1_000345

BRD-A24228527-001-05-9

BRN 3657947

BSPBio_000313

BSPBio_003117

C07321

C18H20FN3O4

CCRIS 5233

CHEBI:7731

CHEMBL4

CID4583

CPD000058192

D00453

Danoflox

DB01165

DEXTROFLOXACINE

DivK1c_000721

DL 8280

DL-8280

DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin

Effexin

EU-0100904

Exocin

Exocine

Flobacin

Flodemex

Flotavid

Flovid

Floxal

Floxil

Floxin

Floxin (TN)

FLOXIN IN DEXTROSE 5%

FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

Floxin otic

Floxstat

Fugacin

HMS1568P15

HMS1921H12

HMS2090F07

HMS2092B10

HMS502E03

Hoe 280

HOE 280

Hoe-280

I06-0112

I06-0380

IDI1_000721

Inoflox

KBio1_000721

KBio2_001666

KBio2_004234

KBio2_006802

KBio3_002617

KBioGR_000667

KBioSS_001666

Kinflocin

Kinoxacin

Liflox

Lopac0_000904

Loxinter

LS-133259

Marfloxacin

Medofloxine

Mergexin

MLS000028749

MLS001074203

MolPort-000-422-241

MolPort-000-873-068

NCGC00015772-02

NCGC00015772-10

NCGC00094219-01

NCGC00094219-02

NCGC00094219-03

NCGC00094219-04

NCGC00094219-05

NCGC00094219-06

NCGC00178284-01

NCGC00178284-02

NINDS_000721

Novecin

NSC727071

Nufafloqo

O 8757

O8757_SIGMA

Obide

Occidal

Ocuflox

Ofcin

Oflin

Oflocee

Oflocet

Oflocin

Oflodal

Oflodex

Oflodura

Oflox

O-Flox

ofloxacin

Ofloxacin (JP15/USP/INN)

Ofloxacin [USAN:BAN:INN:JAN]

Ofloxacin hydrochloride

Ofloxacin Otic

Ofloxacin, (S)-Isomer

Ofloxacina

Ofloxacina [DCIT]

Ofloxacine

Ofloxacine [French]

Ofloxacino

Ofloxacino [Spanish]

Ofloxacinum

Ofloxacinum [Latin]

Ofloxin

OFLX

Ofus

OFX

Onexacin

Operan

Oprea1_242882

ORF 18489

ORF-28489

Orocin

Otonil

Oxaldin

Pharflox

Praxin

Prestwick0_000237

Prestwick1_000237

Prestwick2_000237

Prestwick3_000237

PT 01

Puiritol

Qinolon

Qipro

Quinolon

Quotavil

Rilox

Ru-43280

S1463_Selleck

SAM002264629

Sinflo

SMR000058192

SPBio_001387

SPBio_002234

Spectrum_001186

SPECTRUM1502044

Spectrum2_001464

Spectrum3_001499

Spectrum4_000324

Spectrum5_001063

STK256723

Tabrin

Taravid

Tariflox

Tarivid

Telbit

Tructum

UNII-A4P49JAZ9H

Uro Tarivid

Viotisone

Visiren

WP-0405

XED

Zanocin

Adalimumab

Approved

Phase 2

331731-18-1

16219006

Synonyms:

331731-18-1

Adalimumab

Adalimumab (genetical recombination)

Adalimumab (genetical recombination) (JAN)

Adalimumab (USAN/INN)

adalimumab-adbm

adalimumab-atto

D02597

Humira

Humira (TN)

Humira Pen

Ig gamma-1 chain C region

Levofloxacin

Approved, Investigational

Phase 1, Phase 2

100986-85-4

149096

Synonyms:

(&#8722

(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate

(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate

(-)-Ofloxacin

(3S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

(3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

(3S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(R)-isomer

(S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylate

(S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(S)-(-)-Ofloxacin

(S)-9-fluoro-2,3-dihydro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylate

(S)-9-fluoro-2,3-dihydro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-Ofloxacin

)-Ofloxacin

100986-85-4

100986-86-5

28266_FLUKA

28266_SIGMA

AC1L3YF8

AC-7593

Aeroquin

Ambap100986-85-4

Anhydrous, levofloxacin

BRD-K09471561-001-06-7

BSPBio_002689

C07660

C18H20FN3O4

C18H20FN3O4.H2O

CCRIS 4073

CCRIS 4074

CHEMBL33

CID149096

CPD000466387

Cravit

Cravit (TN)

Cravit Ophthalmic

D08120

DB01137

d-Levofloxacin

DR 3354

DR3355

DR-3355

DR-3355: L-isomer of ofloxacin

Elequine

Floxacin

Floxel

Floxin

HMS1922J07

HMS2051G04

HMS2090O10

HMS2093E18

HR 355

HR-355

Iquix

KBio2_002199

KBio2_004767

KBio2_007335

KBio3_001909

KBioGR_001605

KBioSS_002199

L0193

Leroxacin

Lesacin

Levaquin

LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER

LEVOFLOXACIN

Levofloxacin (INN)

Levofloxacin [USAN:INN:JAN]

Levofloxacin anhydrous

Levofloxacin hydrate

Levofloxacin tablet, suspension or intravenous

Levofloxacine

Levofloxacine [INN-French]

Levofloxacino

Levofloxacino [INN-Spanish]

Levofloxacinum

Levofloxacinum [INN-Latin]

Levokacin

Levox

Levoxacin

LFX

L-Ofloxacin

LS-133260

LS-171761

LVX

MLS000759524

MLS001165709

MLS001423977

MolPort-002-885-835

Mosardal

MP-376

NCGC00178529-01

Nofaxin

Ofloxacin

Ofloxacin S-(-)-form

Ofloxacin, (S)-isomer

Oftaquix

Quixin

Reskuin

R-Ofloxacin

RWJ 25213-097

RWJ-25213

S-(-)-Ofloxacin

S1940_Selleck

SAM001246758

SMR000466387

SPBio_001891

Spectrum_001719

SPECTRUM1504260

Spectrum2_001676

Spectrum3_000995

Spectrum4_001123

Spectrum5_001438

Tavanic

Volequin

Ustekinumab

Approved, Investigational

Phase 2

815610-63-0

Renal Agents

Phase 1, Phase 2

Cytochrome P-450 CYP1A2 Inhibitors

Phase 1, Phase 2

Cytochrome P-450 CYP3A Inducers

Phase 1, Phase 2

Cytochrome P-450 Enzyme Inhibitors

Phase 1, Phase 2

Topoisomerase Inhibitors

Phase 1, Phase 2

Dermatologic Agents

Phase 2

Nucleic Acid Synthesis Inhibitors

Phase 1, Phase 2

Antibiotics, Antitubercular

Phase 1, Phase 2

Antibodies

Phase 2

Immunoglobulins

Phase 2

Antibodies, Monoclonal

Phase 2

Antitubercular Agents

Phase 1, Phase 2

Maraviroc

Approved, Investigational

Not Applicable

376348-65-1

3002977

Synonyms:

376348-65-1

4,4-difluoro-N-((1S)-3-(exo-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide

4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide

4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide

674782-29-7

AC1MHEFQ

AC-558

Celsentri

Celsentri(TM)

CHEBI:537583

CHEMBL1201187

CHEMBL256907

CID3002977

DB04835

exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide

Isopropyl, 4,4-difluoro-N-((1S)-3-{(1R,3s,5S)-3-(3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)octan-8-yl}-1-phenylpropyl)cyclohexanecarboxamide

LS-182818

maraviroc

Maraviroc

Maraviroc [USAN]

MVC

Pfizer brand OF maraviroc

PRO 140 & Maraviroc

PRO 140 (Anti-CCR5 monoclonal antibody) & exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide

Selzentry

Selzentry(TM)

UK 427857

UK-427,857

UK-427,857 maraviroc (MVC)

UK-427857

UNII-MD6P741W8A

Anesthetics

Not Applicable

Pharmaceutical Solutions

Not Applicable

Anti-HIV Agents

Not Applicable

Anti-Retroviral Agents

Not Applicable

Antiviral Agents

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial	Unknown status	NCT02348905	Phase 2, Phase 3	ACTHAR Gel 40 units twice weekly;ACTHAR Gel 80 units twice weekly.
2	The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis	Completed	NCT00794274	Phase 2, Phase 3	CC-100004
3	SARCOTHAL. Thalidomide in Skin Sarcoidosis	Completed	NCT00305552	Phase 3	THALIDOMIDE
4	A Study of Adalimumab to Treat Sarcoidosis of the Skin	Completed	NCT00274352	Phase 2	adalimumab
5	Trial of Antimycobacterial Therapy in Sarcoidosis	Completed	NCT01074554	Phase 1, Phase 2	Antibiotic Regimen;Placebo Regimen
6	A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis	Completed	NCT00955279	Phase 2	Placebo;Golimumab;Ustekinumab
7	A Phase 2 Study With CC-220 in Skin Sarcoidosis	Withdrawn	NCT02192489	Phase 2	CC-220 0.3 mg Daily;CC-220 0.6mg Daily;Placebo
8	Efficacy Study of Humira in the Treatment of Cutaneous Sarcoidosis	Withdrawn	NCT00731757	Phase 2	Humira
9	Study to Determine the Efficacy of Adalimumab in the Treatment of Cutaneous Sarcoidosis	Withdrawn	NCT00690911	Phase 2	adalimumab
10	Impact of Chemokine Receptor 5 (CCR5) Inhibition on Sarcoidosis Immunophenotypes	Terminated	NCT02134717	Not Applicable	all subjects will receive maraviroc 300mg orally twice a day for 6 weeks

Search NIH Clinical Center for Skin Sarcoidosis

Sources

Genetic Tests for Skin Sarcoidosis

Sources

Anatomical Context for Skin Sarcoidosis

MalaCards organs/tissues related to Skin Sarcoidosis:

⁴¹

Skin, Thyroid

Sources

Publications for Skin Sarcoidosis

Articles related to Skin Sarcoidosis:

(show top 50) (show all 61)

#	Title	Authors	Year
1	Narrow-band UVB for pretibial (necrobiosis lipoidica-like) involvement of cutaneous sarcoidosis: a promising therapeutic option. ( 28681723 )	Kuroda K....Iwatsuki K.	2017
2	Cutaneous sarcoidosis during rituximab treatment for microscopic polyangiitis: an uncommon adverse effect? ( 29165307 )	Pescitelli L....Prignano F.	2017
3	A granulomatous conundrum: Concurrent necrobiosis lipoidica, cutaneous sarcoidosis and erythema nodosum in a nondiabetic patient. ( 28211041 )	Valecha N....Yip L.	2017
4	Resolution of Cutaneous Sarcoidosis Following Topical Application of Ganoderma lucidum (Reishi Mushroom). ( 26868374 )	Saylam Kurtipek G....Toksoz M.R.	2016
5	Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - case report. ( 27646659 )	Vatanchi M....Meffert J.J.	2016
6	Cutaneous sarcoidosis and macular amyloidosis occurring at the same site. ( 27297271 )	Karmakar S....Ramesh V.	2016
7	Plantar subcutaneous sarcoidosisA -A a rare form of skin sarcoidosis: unusual plantar aponeurosis location of sarcoidosis as primary manifestation of asymptomatic systemic disease. ( 26865475 )	Janegova A....Babal P.	2016
8	Is it a sarcoidal foreign-body granuloma or a cutaneous sarcoidosis on a permanent eyebrow make-up? ( 26073118 )	Tukenmez Demirci G....GA1leAs A.T.	2016
9	Cutaneous sarcoidosis with granuloma formation around nerves mimicking mycobacterial infection. ( 25869122 )	Zhang Q....Liu H.	2015
10	Cutaneous sarcoidosis simulating porokeratosis of Mibelli. ( 26113926 )	Elfatoiki F.Z....Benchikhi H.	2015
11	A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis. ( 26578505 )	Akyol L....Sayarlioglu M.	2015
12	Perineural granulomas in cutaneous sarcoidosis may be associated with sarcoidosis small fiber neuropathy. ( 25757612 )	Munday W.R....Galan A.	2015
13	Evaluation of cardiac involvement in caucasian patients with skin sarcoidosis. ( 25598240 )	Drago F....Parodi A.	2015
14	Cutaneous Sarcoidosis: Preamble of a Paucisymptomatic Systemic Disease. ( 25823568 )	RamA-rez Huaranga M.A....BellA^n Guardia M.	2015
15	Successful application of a novel dressing for the treatment of ulcerative cutaneous sarcoidosis. ( 24033979 )	Chen J.H....Lin Z.Q.	2013
16	A syringotropic variant of cutaneous sarcoidosis: presentation of 3 cases exhibiting defective sweating responses. ( 23374232 )	Hayakawa J....Shiohara T.	2013
17	Cutaneous sarcoidosis and infliximab: evidence for efficacy in refractory disease. ( 23651297 )	Tu J....Chan J.	2013
18	Isolated cutaneous sarcoidosis: a new insight into the old entity. ( 24086892 )	Kumar H K S....T R.	2013
19	Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy. ( 23675767 )	Joshita S....Ota M.	2013
20	Oral minocycline in treatment of cutaneous sarcoidosis. ( 23783160 )	Steen T....English J.C.	2013
21	Comparison of cutaneous sarcoidosis with systemic sarcoidosis: a retrospective analysis. ( 24427359 )	Tong C....He Y.	2013
22	Diagnosis of cutaneous sarcoidosis; clinical and the prognostic significance of skin lesions. ( 23521826 )	Yanardag H....Iscimen A.	2013
23	Exacerbation of recalcitrant cutaneous sarcoidosis with adalimumab - a paradoxical effect? A case report. ( 24346872 )	Santos G....JoALo A.M.	2013
24	Reliability and convergent validity of the cutaneous sarcoidosis activity and morphology instrument for assessing cutaneous sarcoidosis. ( 23677081 )	Rosenbach M....Gelfand J.M.	2013
25	Cutaneous sarcoidosis with livedoid lesions: evidence of the involvement of Propionibacterium acnes. ( 23731481 )	Asahina A....Eishi Y.	2013
26	Granulomatous cutaneous sarcoidosis: diagnosis, relationship to systemic disease, prognosis and treatment. ( 24351618 )	MaA+A! J....Pujol R.	2013
27	Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study. ( 23863960 )	Drake W.P....King L.E.	2013
28	A double-blind, randomized, placebo-controlled trial of adalimumab in the treatment of cutaneous sarcoidosis. ( 23276549 )	Pariser R.J....Smith M.	2013
29	Verrucous cutaneous sarcoidosis: case report and review of this unusual variant of cutaneous sarcoidosis. ( 23344007 )	Stockman D.L....Plaza J.A.	2013
30	A case series of refractory cutaneous sarcoidosis successfully treated with infliximab. ( 23205333 )	Tuchinda P....Gaspari A.A.	2012
31	Development of cutaneous sarcoidosis during treatment with tumour necrosis alpha factor antagonists. ( 23157794 )	Lamrock E....Brown P.	2012
32	Unusual manifestation of cutaneous sarcoidosis: a case report of morpheaform sarcoidosis. ( 23165817 )	Vasaghi A....Kalafi A.	2012
33	Genetic predisposition to cutaneous sarcoidosis. ( 23275292 )	Shahkarami S....Rezaei N.	2012
34	Pleomorphic cutaneous sarcoidosis confined to lesions of vitiligo vulgaris in a patient with type 1 diabetes mellitus. ( 23075651 )	Chhabra N....Singal A.	2012
35	Cutaneous sarcoidosis clinically mimicking necrobiosis lipoidica in a patient with systemic sarcoidosis. ( 22363160 )	Chiba T....Furue M.	2012
36	Pulmonary and cutaneous sarcoidosis in a treated case of renal tuberculosis. ( 22421674 )	Gupta L.K....Kuldeep C.M.	2012
37	Clinical and histopathological analysis of specific lesions of cutaneous sarcoidosis in Korean patients. ( 20524878 )	Jung Y.J....Roh M.R.	2011
38	Hansen's disease: an imitator of cutaneous sarcoidosis. ( 21963758 )	Chinen K....Fujioka Y.	2011
39	Cutaneous sarcoidosis in a woman with chronic hepatitis C and interferon therapy: a case report. ( 21053557 )	Song K....Das K.	2010
40	Atrophic sarcoidosis: an unusual presentation of cutaneous sarcoidosis. ( 20839429 )	Dogra S....Pahwa M.	2010
41	A rare case of pulmonary tuberculosis with simultaneous pulmonary and skin sarcoidosis: a case report. ( 20205764 )	Mise K....Peric I.	2010
42	Refractory chronic cutaneous sarcoidosis responsive to dose escalation of TNF-alpha antagonists. ( 19468200 )	Thielen A.M....Laffitte E.	2009
43	Hepatic, ocular, and cutaneous sarcoidosis. ( 18539241 )	Rose A.S....Knox K.S.	2008
44	Clinical resolution of facial cutaneous sarcoidosis with systemic colchicine and a topical corticosteroid ointment. ( 18833787 )	Wise R.D.	2008
45	Cutaneous sarcoidosis successfully treated with alefacept. ( 17241600 )	Garcia-Zuazaga J....Korman N.J.	2006
46	Cutaneous sarcoidosis masquerading as lepromatous leprosy. ( 17402349 )	Rai V.M....Mathew M.	2006
47	Newer therapies for cutaneous sarcoidosis: the role of thalidomide and other agents. ( 15663335 )	Baughman R.P....Lower E.E.	2004
48	The use of infliximab in cutaneous sarcoidosis. ( 12884466 )	Meyerle J.H....Shorr A.	2003
49	Progressive cutaneous sarcoidosis responding to anti-tumor necrosis factor-alpha therapy. ( 12582407 )	Mallbris L....StAYhle-BAockdahl M.	2003
50	Cutaneous sarcoidosis. ( 16088652 )	Epstein W.L.	2002

Sources

Genes for Skin Sarcoidosis

Genes related to Skin Sarcoidosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ACE	Angiotensin I Converting Enzyme	Protein Coding	15.73	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	15.44	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	TNF	Tumor Necrosis Factor	Protein Coding	15.09	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	CD83	CD83 Molecule	Protein Coding	14.44	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	ADK	Adenosine Kinase	Protein Coding	14.42	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	SERPINF1	Serpin Family F Member 1	Protein Coding	14.25	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Skin Sarcoidosis

Sources

Expression for Skin Sarcoidosis

Search GEO for disease gene expression data for Skin Sarcoidosis.

Sources

Pathways for Skin Sarcoidosis

Pathways related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	11.65	CD83 TNF TNFRSF1B
2	TNF signaling pathway ³⁷	11.49	TNF TNFRSF1B
3	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.3	CD83 TNF
4	Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway ²² Show member pathways Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway ²²	11.27	TNF TNFRSF1B
5	Adipocytokine signaling pathway ³⁷	11.21	TNF TNFRSF1B
6	Transcription_NF-kB signaling pathway ²²	11.05	TNF TNFRSF1B
7	Cellular Transformation by HTLV1 ⁶⁴ Show member pathways Activation of NF-KappaB by PKR ⁶⁴	10.96	TNF TNFRSF1B
8	Interleukin-10 signaling ⁶⁶	10.85	TNF TNFRSF1B
9	14-3-3 and Regulation of BAD Activity ⁶⁴	10.13	TNF TNFRSF1B

Sources

GO Terms for Skin Sarcoidosis

Cellular components related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	8.8	ACE CD83 TNF

Biological processes related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of inflammatory response	GO:0050728	9.4	SERPINF1 TNFRSF1B
2	kidney development	GO:0001822	9.37	ACE SERPINF1
3	apoptotic signaling pathway	GO:0097190	9.32	TNF TNFRSF1B
4	humoral immune response	GO:0006959	9.26	CD83 TNF
5	intrinsic apoptotic signaling pathway in response to DNA damage	GO:0008630	9.16	TNF TNFRSF1B
6	extrinsic apoptotic signaling pathway	GO:0097191	8.96	TNF TNFRSF1B
7	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	8.62	TNF TNFRSF1B

Sources

Sources for Skin Sarcoidosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia