Skin Sarcoidosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: SKN006 MIFTS: 43	Skin Sarcoidosis Categories: Immune diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Skin Sarcoidosis

MalaCards integrated aliases for Skin Sarcoidosis:

Name: Skin Sarcoidosis ¹² ¹⁵

Cutaneous Sarcoidosis ¹² ⁷³

Cutaneous Sarcoid ¹²

Classifications:

MalaCards categories:
Anatomical: Immune diseases Skin diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

Certain disorders involving the immune mechanism

Sarcoidosis

Sarcoidosis of skin

External Ids:

Disease Ontology ¹² DOID:13402

ICD10 ³³ D86.3

NCIt ⁵⁰ C34996

SNOMED-CT ⁶⁸ 55941000

UMLS ⁷³ C0036203

Sources

Summaries for Skin Sarcoidosis

MalaCards based summary : Skin Sarcoidosis, also known as cutaneous sarcoidosis, is related to sarcoidosis 1 and vasculitis. An important gene associated with Skin Sarcoidosis is ACE (Angiotensin I Converting Enzyme), and among its related pathways/superpathways are NF-kappaB Signaling and TNF signaling pathway. The drugs Apremilast and Neurotransmitter Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and thyroid, and related phenotypes are cardiovascular system and endocrine/exocrine gland

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Related Diseases for Skin Sarcoidosis

Diseases related to Skin Sarcoidosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 124)

#	Related Disease	Score	Top Affiliating Genes
1	sarcoidosis 1	30.5	ACE TNF TNFRSF1B
2	vasculitis	29.3	TNF TNFRSF1B
3	blau syndrome	11.1
4	hepatitis	10.1
5	bladder neck obstruction	10.1	ACE TNFRSF1B
6	hepatitis c	10.1
7	uveoparotid fever	10.1	ACE TNF
8	subacute cutaneous lupus erythematosus	10.1	ACE TNF
9	posterior urethral valves	10.1	ACE TNF
10	ischemic heart disease	10.1	ACE TNF
11	juvenile ankylosing spondylitis	10.1	TNF TNFRSF1B
12	spondylitis	10.1	TNF TNFRSF1B
13	chronic gonococcal salpingitis	10.1	TNF TNFRSF1B
14	scleral disease	10.1	TNF TNFRSF1B
15	pustulosis of palm and sole	10.1	TNF TNFRSF1B
16	rheumatoid lung disease	10.1	TNF TNFRSF1B
17	extrinsic cardiomyopathy	10.1	ACE TNF
18	peroneal neuropathy	10.1	TNF TNFRSF1B
19	rheumatic heart disease	10.1	ACE TNF
20	periodic fever, familial, autosomal dominant	10.1	TNF TNFRSF1B
21	acute salpingitis	10.1	TNF TNFRSF1B
22	pyelonephritis	10.1	ACE TNF
23	post-transplant lymphoproliferative disease	10.1	TNF TNFRSF1B
24	limb ischemia	10.1	ACE TNF
25	chronic salpingitis	10.1	TNF TNFRSF1B
26	exanthem	10.1	TNF TNFRSF1B
27	silicosis	10.1	ACE TNF
28	panuveitis	10.1	TNF TNFRSF1B
29	carotid stenosis	10.1	ACE TNF
30	cogan syndrome	10.1	TNF TNFRSF1B
31	adult respiratory distress syndrome	10.1	ACE TNF
32	palindromic rheumatism	10.1	TNF TNFRSF1B
33	retinal vascular disease	10.1	ACE SERPINF1
34	pulmonary sarcoidosis	10.1	ACE TNF
35	uveal disease	10.1	TNF TNFRSF1B
36	pulmonary edema	10.1	ACE TNF
37	guillain-barre syndrome	10.1	TNF TNFRSF1B
38	sleep apnea	10.1	ACE TNF
39	eales disease	10.1	SERPINF1 TNF
40	end stage renal failure	10.1	ACE TNF
41	vascular dementia	10.1	ACE TNF
42	spondyloarthropathy 1	10.1	TNF TNFRSF1B
43	primary bacterial infectious disease	10.0	TNF TNFRSF1B
44	bone inflammation disease	10.0	TNF TNFRSF1B
45	microvascular complications of diabetes 5	10.0	ACE SERPINF1
46	arteries, anomalies of	10.0	ACE TNF
47	glucose metabolism disease	10.0	ACE TNF
48	juvenile rheumatoid arthritis	10.0	TNF TNFRSF1B
49	immune system disease	10.0	ACE TNF
50	otosclerosis	10.0	ACE SERPINF1

Graphical network of the top 20 diseases related to Skin Sarcoidosis:

Sources

Symptoms & Phenotypes for Skin Sarcoidosis

MGI Mouse Phenotypes related to Skin Sarcoidosis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	9.77	ACE CD83 SERPINF1 TNF TNFRSF1B
2	endocrine/exocrine gland	MP:0005379	9.72	ACE CD83 SERPINF1 TNF TNFRSF1B
3	hematopoietic system	MP:0005397	9.65	ACE CD83 SERPINF1 TNF TNFRSF1B
4	immune system	MP:0005387	9.55	ACE CD83 SERPINF1 TNF TNFRSF1B
5	liver/biliary system	MP:0005370	9.26	ACE ADK TNF TNFRSF1B
6	vision/eye	MP:0005391	8.92	ADK SERPINF1 TNF TNFRSF1B

Sources

Drugs & Therapeutics for Skin Sarcoidosis

Drugs for Skin Sarcoidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 47)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Apremilast

Approved, Investigational

Phase 2, Phase 3

608141-41-9

11561674

Synonyms:

Apremilast

Aprémilast

Apremilast (USAN)

Apremilastum

CC-10004

CHEBI:558773

CHEMBL514800

CID11561674

D08860

N-[2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methylsulfonyl-ethyl]-1,3-dioxo-isoindol-4-yl]acetamide

N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide

Neurotransmitter Agents

Phase 2, Phase 3

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 2, Phase 3

Hormones

Phase 2, Phase 3

beta-endorphin

Phase 2, Phase 3

Melanocyte-Stimulating Hormones

Phase 2, Phase 3

Hormone Antagonists

Phase 2, Phase 3

Endorphins

Phase 2, Phase 3

Adrenocorticotropic Hormone

Phase 2, Phase 3

Immunologic Factors

Phase 2, Phase 3,Phase 3

Anti-Bacterial Agents

Phase 2, Phase 3,Phase 3,Phase 1

Analgesics, Non-Narcotic

Phase 2, Phase 3

Analgesics

Phase 2, Phase 3

Peripheral Nervous System Agents

Phase 2, Phase 3

Immunosuppressive Agents

Phase 2, Phase 3,Phase 3

Anti-Inflammatory Agents, Non-Steroidal

Phase 2, Phase 3

Anti-Infective Agents

Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable

Anti-Inflammatory Agents

Phase 2, Phase 3

Angiogenesis Modulating Agents

Phase 2, Phase 3,Phase 3

Angiogenesis Inhibitors

Phase 2, Phase 3,Phase 3

Antirheumatic Agents

Phase 2, Phase 3

Adalimumab

Approved

Phase 2

331731-18-1

16219006

Synonyms:

331731-18-1

Adalimumab

Adalimumab (genetical recombination)

Adalimumab (genetical recombination) (JAN)

Adalimumab (USAN/INN)

adalimumab-adaz

adalimumab-adbm

adalimumab-atto

D02597

Humira

Humira (TN)

Humira Pen

Ig gamma-1 chain C region

Azithromycin

Approved

Phase 1, Phase 2

83905-01-5

55185 447043

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Levofloxacin

Approved, Investigational

Phase 1, Phase 2

100986-85-4

149096

Synonyms:

(&#8722

(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate

(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate

(-)-Ofloxacin

(3S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate

(3S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

(3S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid

(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(R)-isomer

(S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylate

(S)-(-)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(S)-(-)-9-fluoro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzooxazine-6-carboxylic acid

(S)-(-)-Ofloxacin

(S)-9-fluoro-2,3-dihydro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylate

(S)-9-fluoro-2,3-dihydro-3-Methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(S)-Ofloxacin

)-Ofloxacin

100986-85-4

100986-86-5

28266_FLUKA

28266_SIGMA

AC1L3YF8

AC-7593

Aeroquin

Ambap100986-85-4

Anhydrous, levofloxacin

BRD-K09471561-001-06-7

BSPBio_002689

C07660

C18H20FN3O4

C18H20FN3O4.H2O

CCRIS 4073

CCRIS 4074

CHEMBL33

CID149096

CPD000466387

Cravit

Cravit (TN)

Cravit Ophthalmic

D08120

DB01137

d-Levofloxacin

DR 3354

DR3355

DR-3355

DR-3355: L-isomer of ofloxacin

Elequine

Floxacin

Floxel

Floxin

HMS1922J07

HMS2051G04

HMS2090O10

HMS2093E18

HR 355

HR-355

Iquix

KBio2_002199

KBio2_004767

KBio2_007335

KBio3_001909

KBioGR_001605

KBioSS_002199

L0193

Leroxacin

Lesacin

Levaquin

LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER

LEVOFLOXACIN

Levofloxacin (INN)

Levofloxacin [USAN:INN:JAN]

Levofloxacin anhydrous

Levofloxacin hydrate

Levofloxacin tablet, suspension or intravenous

Levofloxacine

Levofloxacine [INN-French]

Levofloxacino

Levofloxacino [INN-Spanish]

Levofloxacinum

Levofloxacinum [INN-Latin]

Levokacin

Levox

Levoxacin

LFX

L-Ofloxacin

LS-133260

LS-171761

LVX

MLS000759524

MLS001165709

MLS001423977

MolPort-002-885-835

Mosardal

MP-376

NCGC00178529-01

Nofaxin

Ofloxacin

Ofloxacin S-(-)-form

Ofloxacin, (S)-isomer

Oftaquix

Quixin

Reskuin

R-Ofloxacin

RWJ 25213-097

RWJ-25213

S-(-)-Ofloxacin

S1940_Selleck

SAM001246758

SMR000466387

SPBio_001891

Spectrum_001719

SPECTRUM1504260

Spectrum2_001676

Spectrum3_000995

Spectrum4_001123

Spectrum5_001438

Tavanic

Volequin

Ethambutol

Approved

Phase 1, Phase 2

74-55-5

3279 14052

Synonyms:

(-)-(R,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-(S,S)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(+)-2,2'-(ethylenediimino)di-1-butanol

(+)-2,2'-(ethylenediimino)Di-1-butanol

(+)-2,2'-(Ethylenediimino)di-1-butanol

(+)-ethambutol

(+)-Ethambutol

(+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-N,N'-Bis(1-(hydroxymethyl)propyl)ethylenediamine

(+)-S,S-ethambutol

(+)-S,S-Ethambutol

(2R)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2'S)-2,2'-[Ethane-1,2-diyldi(imino)]dibutan-1-ol

(2S)-2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

(2S)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol

(2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

(2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol

(2S,7S)-2,7-Diethyl-3,6-diazaoctane-1,8-diol

(R)-2,2'-(1,2-Ethanediyldiimino)bis-1-butanol

(S,R)-2,2'-(1,2-Ethylenediimino)-di-1-butanol

(S,S)-ethambutol

(S,S)-Ethambutol

1070-11-7

2,2'-(1,2-Ethylenediimino)-di-1-butanol

2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol

2-[2-(1-hydroxybutan-2-ylamino)ethylamino]butan-1-ol

74-55-5

75343-56-5

AC1L1FKQ

AC1L230T

AC1L9YT2

AC1LABPH

AC1LAKIP

AC1LAKIS

AC1Q2C85

AC1Q2SHV

AC1Q77PZ

Aethambutolum

AHP brand OF ethambutol hydrochloride

AR-1A7805

AR-1C2065

BPBio1_000105

BSPBio_000095

BSPBio_002012

C06984

C10H24N2O2

CAS-1070-11-7

CHEBI:4877

CHEMBL43824

CHEMBL44884

CID14052

CID3279

CID465436

CID470071

CID470072

CID504259

CL 40881 (dihydrochloride)

CPD000046147

d,N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

D07925

D-2,2'-(Ethylenediimino)bis(1-butanol)

D-2,2'-(Ethylenediimino)di-1-butanol

Dadibutol

DB00330

D-Ethambutol

Dexambutol

Diambutol

DivK1c_000561

D-N,N'-Bis(1-hydroxymethylpropyl)ethylenediamine

EINECS 200-810-6

Elan brand OF ethambutol hydrochloride

EMB

EMB fatol

EMB hefa

EMB-fatol

EMB-hefa

Etambutol

Etambutol [INN-Spanish]

Etambutol llorente

Etambutolo

Etambutolo [DCIT]

ethambutol

Ethambutol

Ethambutol & EEP

Ethambutol & Propolis

Ethambutol (INN)

Ethambutol [INN:BAN]

Ethambutol dihydrochloride

Ethambutol HCL

Ethambutol hydrochloride

Ethambutol Hydrochloride

Ethambutol, (-)-isomer

Ethambutol, meso form

Ethambutol, racemic mixture

Ethambutolum

Ethambutolum [INN-Latin]

Etibi

Fatol brand OF ethambutol hydrochloride

Genopharm brand OF ethambutol hydrochloride

HSDB 3078

Hydrochloride, ethambutol

ICN brand OF ethambutol hydrochloride

IDI1_000561

KBio1_000561

KBio2_001538

KBio2_004106

KBio2_006674

KBio3_001232

KBioGR_001209

KBioSS_001538

KST-1A8084

Lederle brand OF ethambutol hydrochloride

Llorente brand OF ethambutol hydrochloride

Llorente, etambutol

LS-187119

LS-46537

Miambutol

MLS000082702

MolPort-002-507-956

MolPort-003-847-110

Myambutol

Myambutol (dihydrochloride)

NCGC00016560-01

NCGC00178864-01

NCGC00179661-01

NINDS_000561

NSC653313

Prestwick0_000028

Prestwick1_000028

Prestwick2_000028

Prestwick3_000028

Purderal

Riemser brand OF ethambutol hydrochloride

S,S-Ethambutol

SAM002589988

Sanavita brand OF ethambutol hydrochloride

SERB brand OF ethambutol hydrochloride

Servambutol

Servambutol (TN)

SMR000046147

SPBio_001167

SPBio_002016

Spectrum_001058

Spectrum2_001014

Spectrum3_000426

Spectrum4_000545

Spectrum5_000702

STK711105

STOCK5S-98432

Tibutol

UNII-8G167061QZ

Wernigerode brand OF ethambutol hydrochloride

Wyeth brand OF ethambutol hydrochloride

Ofloxacin

Approved

Phase 1, Phase 2

82419-36-1

4583

Synonyms:

( -)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazin-6-carbonsaeure

(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperaz inyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid

(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

(+/-)-Floxin

118120-51-7 (hydrochloride)

33703_FLUKA

33703_RIEDEL

82419-36-1

83380-47-6

85344-55-4

8-fluoro-3-Methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylate

8-fluoro-3-Methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

AB00513820

AC1L1IHM

AC-7616

AKOS001033517

Bactocin

BB_SC-1252

BPBio1_000345

BRD-A24228527-001-05-9

BRN 3657947

BSPBio_000313

BSPBio_003117

C07321

C18H20FN3O4

CCRIS 5233

CHEBI:7731

CHEMBL4

CID4583

CPD000058192

D00453

Danoflox

DB01165

DEXTROFLOXACINE

DivK1c_000721

DL 8280

DL-8280

DL-8280, HOE-280, Exocin, Flobacin, Floxin, Floxil, Monoflocet, Ofloxacin

Effexin

EU-0100904

Exocin

Exocine

Flobacin

Flodemex

Flotavid

Flovid

Floxal

Floxil

Floxin

Floxin (TN)

FLOXIN IN DEXTROSE 5%

FLOXIN IN DEXTROSE 5% IN PLASTIC CONTAINER

Floxin otic

Floxstat

Fugacin

HMS1568P15

HMS1921H12

HMS2090F07

HMS2092B10

HMS502E03

Hoe 280

HOE 280

Hoe-280

I06-0112

I06-0380

IDI1_000721

Inoflox

KBio1_000721

KBio2_001666

KBio2_004234

KBio2_006802

KBio3_002617

KBioGR_000667

KBioSS_001666

Kinflocin

Kinoxacin

Liflox

Lopac0_000904

Loxinter

LS-133259

Marfloxacin

Medofloxine

Mergexin

MLS000028749

MLS001074203

MolPort-000-422-241

MolPort-000-873-068

NCGC00015772-02

NCGC00015772-10

NCGC00094219-01

NCGC00094219-02

NCGC00094219-03

NCGC00094219-04

NCGC00094219-05

NCGC00094219-06

NCGC00178284-01

NCGC00178284-02

NINDS_000721

Novecin

NSC727071

Nufafloqo

O 8757

O8757_SIGMA

Obide

Occidal

Ocuflox

Ofcin

Oflin

Oflocee

Oflocet

Oflocin

Oflodal

Oflodex

Oflodura

Oflox

O-Flox

ofloxacin

Ofloxacin (JP15/USP/INN)

Ofloxacin [USAN:BAN:INN:JAN]

Ofloxacin hydrochloride

Ofloxacin Otic

Ofloxacin, (S)-Isomer

Ofloxacina

Ofloxacina [DCIT]

Ofloxacine

Ofloxacine [French]

Ofloxacino

Ofloxacino [Spanish]

Ofloxacinum

Ofloxacinum [Latin]

Ofloxin

OFLX

Ofus

OFX

Onexacin

Operan

Oprea1_242882

ORF 18489

ORF-28489

Orocin

Otonil

Oxaldin

Pharflox

Praxin

Prestwick0_000237

Prestwick1_000237

Prestwick2_000237

Prestwick3_000237

PT 01

Puiritol

Qinolon

Qipro

Quinolon

Quotavil

Rilox

Ru-43280

S1463_Selleck

SAM002264629

Sinflo

SMR000058192

SPBio_001387

SPBio_002234

Spectrum_001186

SPECTRUM1502044

Spectrum2_001464

Spectrum3_001499

Spectrum4_000324

Spectrum5_001063

STK256723

Tabrin

Taravid

Tariflox

Tarivid

Telbit

Tructum

UNII-A4P49JAZ9H

Uro Tarivid

Viotisone

Visiren

WP-0405

XED

Zanocin

Rifampicin

Approved

Phase 1, Phase 2

13292-46-1

5458213 5381226

Synonyms:

13292-46-1

1-b]furan-21-yl acetate

3-(((4-Methyl-1-piperazinyl)imino)-methyl)rifamycin

3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)rifamycin SV

3-(4-Methylpiperazinyliminomethyl)-rifamycin SV

3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV

3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin

46713_FLUKA

46713_RIEDEL

62534-43-4

8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV

8-(4-Methylpiperazinyliminomethyl) rifamycin SV

8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin

8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv

8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv

83907_FLUKA

83907_SIGMA

8CI)

Abrifam

Archidyn

Arficin

Arzide

AZT + Rifampin

Ba 41166

Ba 41166/E

BA-41166E

Benemicin

Benemycin

BIDD:PXR0014

Bio-0621

BPBio1_000561

BSPBio_000509

C06688

C43H58N4O12

CAS-13292-46-1

CCRIS 551

CHEBI:28077

CHEBI:455936

CHEMBL180

CID5381226

CID5388984

CID5458213

CID5702112

CID6604339

CID6708473

CID6842115

CID6912767

CID6913622

CPD001906767

D00211

DB01045

Dione 21-acetate

Dipicin

DivK1c_000550

Doloresum

DRG-0109

EINECS 236-312-0

Eremfat

Famcin

Fenampicin

HMS1569J11

HMS1920P08

HMS2089F12

HMS2092G09

HMS501L12

HSDB 3181

KBio1_000550

KBio2_000919

KBio2_003487

KBio2_006055

KBio3_003018

KBioGR_001780

KBioSS_000919

L-5103

L-5103 Lepetit

LS-7689

MLS000028552

MLS001148237

MLS001333745

MolPort-000-767-051

MolPort-002-513-586

MolPort-003-666-281

MolPort-006-395-891

NCGC00016699-01

NCGC00017365-01

NCGC00018178-01

NCGC00022678-03

NCGC00022678-04

NCGC00022678-05

NCGC00160500-01

nchembio884-comp4

NCI60_000309

NINDS_000550

NSC 113926

NSC113926

NSC-113926

Piperine & Rifampicin

Prestwick_833

Prestwick0_000525

Prestwick1_000525

Prestwick2_000525

Prestwick3_000525

R/AMP

R0079

R3501_SIAL

R3501_SIGMA

R5777_SIGMA

R7382_SIGMA

Ramp

RAMP

R-Cin

Reserpine & Rifampicin

Rfamipicin

RFP

Rifa

Rifadin

Rifadin (TN)

Rifadin I.V

Rifadin I.V.

Rifadin Iv

Rifadin IV

Rifadin, Rimactane, Rifampicin, Rifampin

Rifadine

Rifagen

Rifaldazin

Rifaldazine

Rifaldin

Rifam

Rifamicin AMP

Rifamor

Rifampicin

Rifampicin & EEP

Rifampicin & Propolis

Rifampicin (JP15/INN)

Rifampicin [INN:BAN:JAN]

Rifampicin SV

Rifampicina

Rifampicina [INN-Spanish]

Rifampicine

Rifampicine [French]

Rifampicinum

Rifampicinum [INN-Latin]

rifampin

Rifampin

Rifampin (USP)

Rifampin [USAN]

Rifamsolin

Rifamycin

Rifamycin Amp

Rifamycin AMP

Rifaprodin

Rifcin

Rifinah

Rifobac

Rifoldin

Rifoldine

Riforal

Rimactan

Rimactane

Rimactane (TN)

Rimactazid

Rimactin

Rimactizid

Rimazid

Rimycin

RMP

Rofact

S1764_Selleck

SAM002264646

Sinerdol

SMR000058322

SMR000653525

SPBio_002430

Spectrum_000439

SPECTRUM1500529

Spectrum3_001837

Spectrum4_001250

Spectrum5_002018

STK080143

TNP00313

Tubocin

UNII-VJT6J7R4TR

WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1

Ustekinumab

Approved, Investigational

Phase 2

815610-63-0

Cytochrome P-450 CYP3A Inducers

Phase 1, Phase 2

Renal Agents

Phase 1, Phase 2

Antitubercular Agents

Phase 1, Phase 2

Cytochrome P-450 Enzyme Inhibitors

Phase 1, Phase 2

Nucleic Acid Synthesis Inhibitors

Phase 1, Phase 2

Cytochrome P-450 CYP1A2 Inhibitors

Phase 1, Phase 2

Antibiotics, Antitubercular

Phase 1, Phase 2

Topoisomerase Inhibitors

Phase 1, Phase 2

Anti-Infective Agents, Urinary

Phase 1, Phase 2

Dermatologic Agents

Phase 2

Antibodies, Monoclonal

Phase 2

Antibodies

Phase 2

Immunoglobulins

Phase 2

Maraviroc

Approved, Investigational

Not Applicable

376348-65-1

3002977

Synonyms:

376348-65-1

4,4-difluoro-N-((1S)-3-(exo-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide

4,4-Difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide

4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide

674782-29-7

AC1MHEFQ

AC-558

Celsentri

Celsentri(TM)

CHEBI:537583

CHEMBL1201187

CHEMBL256907

CID3002977

DB04835

exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide

Isopropyl, 4,4-difluoro-N-((1S)-3-{(1R,3s,5S)-3-(3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)octan-8-yl}-1-phenylpropyl)cyclohexanecarboxamide

LS-182818

maraviroc

Maraviroc

Maraviroc [USAN]

MVC

Pfizer brand OF maraviroc

PRO 140 & Maraviroc

PRO 140 (Anti-CCR5 monoclonal antibody) & exo-4,4-Difluoro-N-[3-[3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]oct-8-yl]-1(S)-phenylpropyl]cyclohexanecarboxamide

Selzentry

Selzentry(TM)

UK 427857

UK-427,857

UK-427,857 maraviroc (MVC)

UK-427857

UNII-MD6P741W8A

Antiviral Agents

Not Applicable

Pharmaceutical Solutions

Not Applicable

Anti-HIV Agents

Not Applicable

Anesthetics

Not Applicable

Anti-Retroviral Agents

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial	Unknown status	NCT02348905	Phase 2, Phase 3	ACTHAR Gel 40 units twice weekly;ACTHAR Gel 80 units twice weekly.
2	The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis	Completed	NCT00794274	Phase 2, Phase 3	CC-100004
3	SARCOTHAL. Thalidomide in Skin Sarcoidosis	Completed	NCT00305552	Phase 3	THALIDOMIDE
4	A Study of Adalimumab to Treat Sarcoidosis of the Skin	Completed	NCT00274352	Phase 2	adalimumab
5	Trial of Antimycobacterial Therapy in Sarcoidosis	Completed	NCT01074554	Phase 1, Phase 2	Antibiotic Regimen;Placebo Regimen
6	A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis	Completed	NCT00955279	Phase 2	Placebo;Golimumab;Ustekinumab
7	A Phase 2 Study With CC-220 in Skin Sarcoidosis	Withdrawn	NCT02192489	Phase 2	CC-220 0.3 mg Daily;CC-220 0.6mg Daily;Placebo
8	Efficacy Study of Humira in the Treatment of Cutaneous Sarcoidosis	Withdrawn	NCT00731757	Phase 2	Humira
9	Study to Determine the Efficacy of Adalimumab in the Treatment of Cutaneous Sarcoidosis	Withdrawn	NCT00690911	Phase 2	adalimumab
10	Impact of Chemokine Receptor 5 (CCR5) Inhibition on Sarcoidosis Immunophenotypes	Terminated	NCT02134717	Not Applicable	all subjects will receive maraviroc 300mg orally twice a day for 6 weeks

Search NIH Clinical Center for Skin Sarcoidosis

Sources

Genetic Tests for Skin Sarcoidosis

Sources

Anatomical Context for Skin Sarcoidosis

MalaCards organs/tissues related to Skin Sarcoidosis:

⁴¹

Skin, Lung, Thyroid, T Cells, Bone, Heart, Myeloid

Sources

Publications for Skin Sarcoidosis

Articles related to Skin Sarcoidosis:

(show top 50) (show all 287)

#	Title	Authors	Year
1	Cutaneous sarcoidosis after Hodgkin lymphoma. ( 30411336 )	Impivaara S...Kluger N	2018
2	Polymorphous Cutaneous Sarcoidosis Associated with Peripheral Vascular Disease and its Dermatoscopic Findings. ( 30050815 )	Nirmal B...Telugu RB	2018
3	Concurrent Diagnoses of Cutaneous Sarcoidosis and Recurrent Metastatic Breast Cancer: More than a Coincidental Occurrence? ( 30254768 )	Deen J...Wheller L	2018
4	Micropapular Cutaneous Sarcoidosis Reviewed. ( 30278434 )	Labadie JG...Krunic AL	2018
5	The natural history of cutaneous sarcoidosis. Clinical spectrum and histological analysis of 40 cases. ( 30306543 )	Garc?a-Colmenero L...Pujol RM	2018
6	Exploring the dynamic changes between pulmonary and cutaneous sarcoidosis based on gene expression. ( 30403187 )	Sheng Y...Yang Q	2018
7	Oral Fumaderm® to treat cutaneous sarcoidosis. ( 29756252 )	Rolls S...Porter W	2018
8	Cutaneous sarcoidosis: a new subset in the spectrum of paraneoplastic dermatoses. ( 29779211 )	El-Khalawany M...Ali S	2018
9	Physicochemical characterization of inorganic deposits associated with granulomas in cutaneous sarcoidosis. ( 29972866 )	Colboc H...Bernaudin JF	2018
10	Dermoscopy of a single plaque on the face: an uncommon presentation of cutaneous sarcoidosis. ( 30116658 )	Conforti C...Zalaudek I	2018
11	Light and Laser Modalities in the Treatment of Cutaneous Sarcoidosis: A Systematic Review. ( 29242948 )	Lima AL...Elsner P	2018
12	Cutaneous sarcoidosis in a patient with rheumatoid arthritis receiving tocilizumab. ( 29500868 )	Shono Y...Tada Y	2018
13	Narrow-band UVB for pretibial (necrobiosis lipoidica-like) involvement of cutaneous sarcoidosis: a promising therapeutic option. ( 28681723 )	Kuroda K....Iwatsuki K.	2017
14	Cutaneous sarcoidosis during rituximab treatment for microscopic polyangiitis: an uncommon adverse effect? ( 29165307 )		2017
15	A granulomatous conundrum: Concurrent necrobiosis lipoidica, cutaneous sarcoidosis and erythema nodosum in a nondiabetic patient. ( 28211041 )		2017
16	Cutaneous sarcoidosis and secondary open-angle glaucoma in a patient: case report and literature review. ( 29186261 )	Deng Q...Huang J	2017
17	Annular lesions of cutaneous sarcoidosis with granulomatous vasculitis. ( 28116823 )	Mizuno K...Okamoto H	2017
18	Recalcitrant Diffuse Cutaneous Sarcoidosis With Perianal Involvement Responding to Adalimumab. ( 29240869 )	Cohen GF...Wolfe CM	2017
19	Quantification of granuloma volume and response to treatment in cutaneous sarcoidosis using 3-dimensional high-frequency ultrasound scan. ( 29264382 )	Rodriguez O...Rosenbach M	2017
20	Annular cutaneous sarcoidosis with systemic involvement. ( 29417028 )	Mishra AK...Peter D	2017
21	Koebnerization phenomenon after broadband light therapy in a patient with cutaneous sarcoidosis. ( 28752117 )	Chesner J...Marmur ES	2017
22	Cutaneous sarcoidosis: A retrospective case series and a hospital-based case-control study in Taiwan. ( 28984765 )	Liu KL...Lee CH	2017
23	Unconventional use of fractional ablative CO2 laser in facial cutaneous sarcoïdosis. ( 29082596 )	Zaouak A...Fenniche S	2017
24	An Adolescent with Extensive Cutaneous Sarcoidosis without Lung Involvement. ( 28213883 )	Mishra P...Das RR	2017
25	Nivolumab-related cutaneous sarcoidosis in a patient with lung adenocarcinoma. ( 28443311 )	Birnbaum MR...McLellan BN	2017
26	Efficacy and Tolerance of Anti-Tumor Necrosis Factor α Agents in Cutaneous Sarcoidosis: A French Study of 46 Cases. ( 28564695 )	Heidelberger V...Valeyre D	2017
27	Cutaneous sarcoidosis. ( 28598873 )	Noe MH...Rosenbach M	2017
28	High frequency ultrasound: a novel instrument to quantify granuloma burden in cutaneous sarcoidosis. ( 29628755 )	Noe MH...Rosenbach M	2017
29	A case of hyaluronic acid injections triggering cutaneous sarcoidosis at previously treated sites. ( 27357733 )	Mermin D...Doutre MS	2017
30	Resolution of Cutaneous Sarcoidosis Following Topical Application of Ganoderma lucidum (Reishi Mushroom). ( 26868374 )	Saylam Kurtipek G....Toksoz M.R.	2016
31	Cutaneous sarcoidosis masquerading as chronic cutaneous lupus erythematosus - case report. ( 27646659 )	Vatanchi M....Meffert J.J.	2016
32	Cutaneous sarcoidosis and macular amyloidosis occurring at the same site. ( 27297271 )		2016
33	Plantar subcutaneous sarcoidosisA -A a rare form of skin sarcoidosis: unusual plantar aponeurosis location of sarcoidosis as primary manifestation of asymptomatic systemic disease. ( 26865475 )		2016
34	Is it a sarcoidal foreign-body granuloma or a cutaneous sarcoidosis on a permanent eyebrow make-up? ( 26073118 )		2016
35	Epidemiology of cutaneous sarcoidosis, 1976-2013: a population-based study from Olmsted County, Minnesota. ( 27324138 )	Ungprasert P...Matteson EL	2016
36	Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept. ( 27992009 )	Vieira MA...Valente NY	2016
37	Cutaneous Sarcoidosis Misdiagnosed as Leprosy. Report of Two Cases and Review of Literature. ( 30207442 )	Chowdhary KN...Pai S	2016
38	Isolated Cutaneous Sarcoidosis. ( 26552871 )	?im?ek A...Yap?c? ?	2016
39	Cutaneous sarcoidosis at insulin injection sites. ( 26783329 )	Zargham H...O'Brien E	2016
40	Infliximab for chronic cutaneous sarcoidosis: a subset analysis from a double-blind randomized clinical trial. ( 26847095 )	Baughman RP...Sarcoidosis Investigators	2016
41	Erythematous patches and pretibial ulcers: an uncommon presentation of cutaneous sarcoidosis. ( 26972195 )	Barisani A...Patrizi A	2016
42	Cutaneous sarcoidosis with zosteriform distribution and pulmonary involvement. ( 27176087 )	Infusino SD...Passarini B	2016
43	Cutaneous sarcoidosis in a melanoma patient under Ipilimumab therapy. ( 27357143 )	Mart?nez Lebor?ns L...Berrocal Jaime A	2016
44	Cutaneous sarcoidosis with granuloma formation around nerves mimicking mycobacterial infection. ( 25869122 )	Zhang Q....Liu H.	2015
45	Cutaneous sarcoidosis simulating porokeratosis of Mibelli. ( 26113926 )	Elfatoiki F.Z....Benchikhi H.	2015
46	A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis. ( 26578505 )	Akyol L....Sayarlioglu M.	2015
47	Perineural granulomas in cutaneous sarcoidosis may be associated with sarcoidosis small fiber neuropathy. ( 25757612 )	Munday W.R....Galan A.	2015
48	Response to letter &quot;evaluation of cardiac involvement in caucasian patients with skin sarcoidosis&quot;. ( 25581211 )		2015
49	Evaluation of cardiac involvement in caucasian patients with skin sarcoidosis. ( 25598240 )		2015
50	Cutaneous Sarcoidosis: Preamble of a Paucisymptomatic Systemic Disease. ( 25823568 )		2015

Sources

Genes for Skin Sarcoidosis

Genes related to Skin Sarcoidosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ACE	Angiotensin I Converting Enzyme	Protein Coding	15.76	DISEASES inferred ¹⁵
2	TNFRSF1B	TNF Receptor Superfamily Member 1B	Protein Coding	15.41	DISEASES inferred ¹⁵
3	TNF	Tumor Necrosis Factor	Protein Coding	15.02	DISEASES inferred ¹⁵
4	ADK	Adenosine Kinase	Protein Coding	14.36	DISEASES inferred ¹⁵
5	CD83	CD83 Molecule	Protein Coding	14.32	DISEASES inferred ¹⁵
6	SERPINF1	Serpin Family F Member 1	Protein Coding	14.16	DISEASES inferred ¹⁵

Sources

Variations for Skin Sarcoidosis

Sources

Expression for Skin Sarcoidosis

Search GEO for disease gene expression data for Skin Sarcoidosis.

Sources

Pathways for Skin Sarcoidosis

Pathways related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	11.65	CD83 TNF TNFRSF1B
2	TNF signaling pathway ³⁷	11.5	TNF TNFRSF1B
3	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.3	CD83 TNF
4	Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway ²² Show member pathways Apoptosis and survival Anti-apoptotic TNFs/NF-kB/IAP pathway ²²	11.27	TNF TNFRSF1B
5	Adipocytokine signaling pathway ³⁷	11.21	TNF TNFRSF1B
6	Transcription_NF-kB signaling pathway ²²	11.05	TNF TNFRSF1B
7	Cellular Transformation by HTLV1 ⁶⁴ Show member pathways Activation of NF-KappaB by PKR ⁶⁴	10.96	TNF TNFRSF1B
8	Interleukin-10 signaling ⁶⁶	10.85	TNF TNFRSF1B
9	14-3-3 and Regulation of BAD Activity ⁶⁴	10.13	TNF TNFRSF1B

Sources

GO Terms for Skin Sarcoidosis

Cellular components related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	8.8	ACE CD83 TNF

Biological processes related to Skin Sarcoidosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of inflammatory response	GO:0050728	9.4	SERPINF1 TNFRSF1B
2	tumor necrosis factor-mediated signaling pathway	GO:0033209	9.37	TNF TNFRSF1B
3	humoral immune response	GO:0006959	9.32	CD83 TNF
4	intrinsic apoptotic signaling pathway in response to DNA damage	GO:0008630	9.26	TNF TNFRSF1B
5	extrinsic apoptotic signaling pathway	GO:0097191	9.16	TNF TNFRSF1B
6	negative regulation of gene expression	GO:0010629	9.13	ACE SERPINF1 TNF
7	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	8.62	TNF TNFRSF1B

Sources

Sources for Skin Sarcoidosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

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