MCID: SKL005
MIFTS: 27

Skull Base Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Skull Base Meningioma

MalaCards integrated aliases for Skull Base Meningioma:

Name: Skull Base Meningioma 12 15 70
Meningioma of the Skull Base 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4437
NCIt 50 C5272
UMLS 70 C1335976

Summaries for Skull Base Meningioma

MalaCards based summary : Skull Base Meningioma, also known as meningioma of the skull base, is related to secretory meningioma and olfactory groove meningioma, and has symptoms including seizures and headache. An important gene associated with Skull Base Meningioma is WT1 (WT1 Transcription Factor). The drug Edotreotide has been mentioned in the context of this disorder. Affiliated tissues include breast, t cells and pituitary.

Related Diseases for Skull Base Meningioma

Diseases in the Skull Base Meningioma family:

Multiple Skull Base Meningioma

Diseases related to Skull Base Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 secretory meningioma 30.9 TRAF7 SMARCE1 SERPINA3 NF2 KLF4
2 olfactory groove meningioma 30.6 TRAF7 NF2
3 meningioma, familial 30.5 TRAF7 SST SMARCE1 SERPINA3 NF2 KLF4
4 foramen magnum meningioma 30.3 SPATA31A1 NF2
5 rare tumor 30.2 SST NF2
6 benign meningioma 30.1 TRAF7 SMARCE1 NF2
7 clear cell meningioma 29.9 TRAF7 SMARCE1 NF2
8 brain meningioma 29.9 TRAF7 SMO NF2
9 meningothelial meningioma 29.7 TRAF7 SMARCE1 SERPINA3 NF2
10 multiple skull base meningioma 11.4
11 intracranial meningioma 10.9
12 lymphoplasmacyte-rich meningioma 10.9
13 pediatric meningioma 10.2 TRAF7 NF2
14 intraventricular meningioma 10.2 TRAF7 NF2
15 psammomatous meningioma 10.2 TRAF7 NF2
16 meninges hemangiopericytoma 10.2 TRAF7 NF2
17 anterior cranial fossa meningioma 10.2 TRAF7 NF2
18 ovarian endometrial cancer 10.2 WT1 SERPINA3
19 proliferative type fibrocystic change of breast 10.2 SERPINA3 EXTL1
20 intraneural perineurioma 10.2 TRAF7 NF2
21 non-proliferative fibrocystic change of the breast 10.2 SERPINA3 EXTL1
22 chordoid meningioma 10.2 TRAF7 NF2
23 rhabdoid meningioma 10.2 TRAF7 NF2
24 adenomatoid tumor 10.2 WT1 TRAF7
25 fibrous meningioma 10.2 TRAF7 NF2
26 iris disease 10.2 WT1 SERPINA3
27 peritoneum cancer 10.2 WT1 NF2
28 type c thymoma 10.2 SST SERPINA3
29 yemenite deaf-blind hypopigmentation syndrome 10.1
30 aspergillosis 10.1
31 ptosis 10.1
32 hydrocephalus 10.1
33 obstructive hydrocephalus 10.1
34 exophthalmos 10.1
35 non-langerhans-cell histiocytosis 10.1 SST SERPINA3
36 synovium cancer 10.1 WT1 SERPINA3
37 benign mesothelioma 10.1 WT1 NF2
38 mn1 c-terminal truncation syndrome 10.1 SMARCE1 NF2
39 pancreatoblastoma 10.1 SST SERPINA3
40 pancreatic endocrine carcinoma 10.1 SST SERPINA3
41 chondrosarcoma 10.1
42 alopecia 10.1
43 peritoneal mesothelioma 10.1 WT1 NF2
44 frontal convexity meningioma 10.1 TRAF7 NF2 KLF4
45 spinal cancer 10.1 SMARCE1 NF2
46 central nervous system benign neoplasm 10.0 SERPINA3 NF2
47 neurofibromatosis, type i 10.0
48 otitis media 10.0
49 trigeminal neuralgia 10.0
50 wilms tumor 1 10.0

Graphical network of the top 20 diseases related to Skull Base Meningioma:



Diseases related to Skull Base Meningioma

Symptoms & Phenotypes for Skull Base Meningioma

UMLS symptoms related to Skull Base Meningioma:


seizures; headache

Drugs & Therapeutics for Skull Base Meningioma

Drugs for Skull Base Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Edotreotide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Hippocampal Sparing on Neurocognitive Functions and Quality of Live in Patients Irradiated in the Neurocranial Area Unknown status NCT01849484 Phase 2
2 Randomized Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial. Not yet recruiting NCT01795300

Search NIH Clinical Center for Skull Base Meningioma

Genetic Tests for Skull Base Meningioma

Anatomical Context for Skull Base Meningioma

MalaCards organs/tissues related to Skull Base Meningioma:

40
Breast, T Cells, Pituitary, Brain, Spinal Cord, Prostate

Publications for Skull Base Meningioma

Articles related to Skull Base Meningioma:

(show top 50) (show all 170)
# Title Authors PMID Year
1
Trends in cerebrospinal fluid leak rates following the extended endoscopic endonasal approach for anterior skull base meningioma: a meta-analysis over the last 20 years. 61
33188605 2021
2
Relationship between Pathological Characteristics and Radiological Findings on Perfusion MR Imaging of Meningioma. 61
33504729 2021
3
Predictors of Survival in Subtotally Resected WHO Grade I Skull Base Meningiomas. 61
33810089 2021
4
Predicting High-Value Care Outcomes After Surgery for Skull Base Meningiomas. 61
33567369 2021
5
High Mib-1-score correlates with new cranial nerve deficits after surgery for frontal skull base meningioma. 61
31834543 2021
6
Short diameter may be a useful simple indicator of the tumor response in skull base meningiomas after conventionally fractionated stereotactic radiotherapy. 61
33569622 2021
7
Outcomes from treatment of asymptomatic skull base meningioma with stereotactic radiosurgery. 61
33211178 2021
8
A Probability-Based Investigation on the Setup Robustness of Pencil-beam Proton Radiation Therapy for Skull-Base Meningioma. 61
33604414 2021
9
Rare Tumor-to-Tumor Metastases Involving Lung Adenocarcinoma to Petroclival Meningiomas. 61
32730974 2020
10
Correction to: Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis. 61
33317569 2020
11
Significance of the simultaneous combined transcranial and endoscopic endonasal approach for prevention of postoperative CSF leak after surgery for lateral skull base meningioma. 61
33222918 2020
12
Minimally invasive surgical treatment of intracranial meningiomas in elderly patients (≥ 65 years): outcomes, readmissions, and tumor control. 61
33002879 2020
13
An Aggressive Extension of Dumbbell-Type Pediatric Skull Base Meningioma: A Case Report with Review of the Literature. 61
32371076 2020
14
Dosimetric Comparison of Hypofractionated Multi-Beam Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy With Flattened Beam and Flattening-Filter-Free Beam for Skull Base Meningioma Adjacent to Optic Pathways. 61
32699688 2020
15
Spontaneous regression of a large skull base meningioma: case report. 61
29334772 2020
16
The utility of 3-dimensional-printed models for skull base meningioma surgery. 61
32355814 2020
17
Occipital to Angular Artery Bypass for Post-irradiation Ischemia: 3-Dimensional Operative Video. 61
31173139 2020
18
Endoscopic technology and repair techniques. 61
32586493 2020
19
Parasellar meningioma presenting by stroke and bilateral occlusion of the internal carotid arteries: A case report. 61
32047631 2020
20
Ventriculoperitoneal shunt placement with ultrasound guidance and laparoscopic assistance: 2-dimensional instructional video. 61
32844047 2020
21
Acute Vision Loss After Ophthalmic Artery Embolization of Meningioma. 61
30893270 2019
22
Skull base versus non-skull base meningioma surgery in the elderly. 61
29978438 2019
23
Feasibility of Bundled Payments in Anterior, Middle, and Posterior Cranial Fossa Skull Base Meningioma Surgery: MarketScan Analysis of Health Care Utilization and Outcomes. 61
31323403 2019
24
Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis. 61
31718650 2019
25
Pneumosinus Dilatans: An exploration into the association between Arachnoid Cyst, Meningioma and the pathogenesis of Pneumosinus Dilatans. 61
31445325 2019
26
Efficacy and Tolerance of Intensity Modulated Radiation Therapy for Skull Base Meningioma. 61
31673652 2019
27
Preliminary experience with a digital robotic exoscope in cranial and spinal surgery: a review of the Synaptive Modus V system. 61
31119395 2019
28
New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses. 61
31565188 2019
29
EQ-5D Quality-of-Life Analysis and Cost-Effectiveness After Skull Base Meningioma Resection. 61
30869135 2019
30
Early Postoperative Complications in Meningioma: Predictive Factors and Impact on Outcome. 61
31082552 2019
31
[Skull base meningioma: Clinical and radiological efficacy based on a quantitative volumetric analysis]. 61
31128988 2019
32
Multisession radiosurgery for perioptic meningiomas: medium-to-long term results from a CyberKnife cooperative study. 61
31119480 2019
33
Implications of Extracranial Distortion in Ultra-High-Field Magnetic Resonance Imaging for Image-Guided Cranial Neurosurgery. 61
30797931 2019
34
The Natural Growth Rate of Skull Base Meningiomas Compared With Non-Skull Base Meningiomas. 61
30908440 2019
35
Resection of a Dumbbell Skull Base Meningioma by a Combined Two-Staged Retrosigmoid and Transzygomatic Transcavernous Approach. 61
31143600 2019
36
Risk group-adapted adjuvant radiotherapy for WHO grade I and II skull base meningioma. 61
30953136 2019
37
Cranial Nerve Outcomes After Surgery for Frontal Skull Base Meningiomas: The Eternal Quest of the Maximum-Safe Resection with the Lowest Morbidity. 61
30738945 2019
38
Placement of cesium-131 permanent brachytherapy seeds using the endoscopic endonasal approach for recurrent anaplastic skull base meningioma: case report and technical note. 61
30835687 2019
39
Lessons learned in the evolution of endoscopic skull base surgery. 61
30717035 2019
40
A rare case of diffuse intracranial aspergillosis masquerading as skull base meningioma in an immunocompetent patient. 61
30232959 2019
41
Metastatic Gallbladder Carcinoma in Meningioma: A Case Report. 61
28731197 2019
42
Correlation of Preoperative Radiological Evaluation of Skull Base and Non-skull Base Meningiomas with Clinical and Surgical Data. 61
30649817 2019
43
Red Blood Cell Transfusions Following Resection of Skull Base Meningiomas: Risk Factors and Clinical Outcomes. 61
30456031 2018
44
Endoscopic endonasal approaches for the management of skull base meningiomas: selection criteria and clinical outcomes. 61
29808635 2018
45
Surgical outcomes after reoperation for recurrent non-skull base meningiomas. 61
30544357 2018
46
Olfactory groove and tuberculum sellae meningioma resection by endoscopic endonasal approach versus transcranial approach: A systematic review and meta-analysis of comparative studies. 61
30193170 2018
47
Progesterone Receptor Is Responsible for Benign Biology of Skull Base Meningioma. 61
30031954 2018
48
Boron Neutron Capture Therapy for High-Grade Skull-Base Meningioma. 61
30210985 2018
49
The Endoscopic Endonasal Management of Anterior Skull Base Meningiomas. 61
30210982 2018
50
Moulded Osteomyofascial Pedicled Split (MOPS) Craniotomy Flap in Reconstruction of Anterior Cranial Fossa Defects: Pilot Study of a Novel Technique. 61
30459859 2018

Variations for Skull Base Meningioma

Expression for Skull Base Meningioma

Search GEO for disease gene expression data for Skull Base Meningioma.

Pathways for Skull Base Meningioma

GO Terms for Skull Base Meningioma

Biological processes related to Skull Base Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription, DNA-templated GO:0045892 9.26 WT1 SMO SMARCE1 KLF4
2 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 9.16 WT1 KLF4
3 negative regulation of cell proliferation GO:0008285 8.92 WT1 SST NF2 KLF4

Sources for Skull Base Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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