MCID: SKL005
MIFTS: 28

Skull Base Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Skull Base Meningioma

MalaCards integrated aliases for Skull Base Meningioma:

Name: Skull Base Meningioma 12 15 74
Meningioma of the Skull Base 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4437
NCIt 51 C5272
UMLS 74 C1335976

Summaries for Skull Base Meningioma

MalaCards based summary : Skull Base Meningioma, also known as meningioma of the skull base, is related to multiple skull base meningioma and meningioma, familial, and has symptoms including seizures and headache. An important gene associated with Skull Base Meningioma is WT1 (WT1 Transcription Factor). The drug Edotreotide has been mentioned in the context of this disorder. Affiliated tissues include bone, pituitary and t cells.

Related Diseases for Skull Base Meningioma

Diseases in the Skull Base Meningioma family:

Multiple Skull Base Meningioma

Diseases related to Skull Base Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 multiple skull base meningioma 12.6
2 meningioma, familial 10.3
3 spinal meningioma 10.3
4 secretory meningioma 10.3
5 otitis media 10.0
6 deafness, autosomal recessive 8 10.0 TMPRSS3 TMPRSS4
7 deafness, autosomal recessive 98 10.0 TMPRSS3 TMPRSS4
8 deafness, autosomal recessive 24 10.0 TMPRSS3 TMPRSS4
9 deafness, autosomal recessive 85 10.0 TMPRSS3 TMPRSS4
10 deafness, autosomal recessive 83 9.9 TMPRSS3 TMPRSS4
11 deafness, autosomal recessive 25 9.9 TMPRSS3 TMPRSS4
12 chondrosarcoma 9.9
13 benign meningioma 9.9
14 deafness, autosomal dominant 2a 9.9 TMPRSS3 TMPRSS4
15 wilms tumor 1 9.9
16 wilms tumor 5 9.9
17 aspergillosis 9.9
18 wilms tumor 6 9.9
19 hydrocephalus 9.9
20 ischemic optic neuropathy 9.9
21 adenoid cystic carcinoma 9.9
22 abducens nerve disease 9.9
23 epilepsy 9.9
24 optic nerve disease 9.9
25 brain edema 9.9
26 neuropathy 9.9
27 anaplastic ependymoma 9.9
28 carcinoid syndrome 9.9
29 ependymoma 9.9
30 ocular neuromyotonia 9.9
31 pseudobulbar affect 9.9
32 deafness, autosomal recessive 16 9.9 TMPRSS3 TMPRSS4
33 deafness, autosomal dominant 6 9.8 TMPRSS3 TMPRSS4
34 petroclival meningioma 9.8 BLVRA TMPRSS4
35 deafness, autosomal dominant 13 9.8 TMPRSS3 TMPRSS4
36 nonsyndromic deafness 9.7 TMPRSS3 TMPRSS4
37 skull base cancer 9.2 AKAP9 BLVRA CCDC174 TMPRSS4

Graphical network of the top 20 diseases related to Skull Base Meningioma:



Diseases related to Skull Base Meningioma

Symptoms & Phenotypes for Skull Base Meningioma

UMLS symptoms related to Skull Base Meningioma:


seizures, headache

Drugs & Therapeutics for Skull Base Meningioma

Drugs for Skull Base Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Edotreotide Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Enhancement of Neurocognitive Functions by Hippocampal Sparing Radiotherapy Recruiting NCT01849484 Phase 2
2 Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery Unknown status NCT02084927 Phase 1
3 Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial. Not yet recruiting NCT01795300 Not Applicable

Search NIH Clinical Center for Skull Base Meningioma

Genetic Tests for Skull Base Meningioma

Anatomical Context for Skull Base Meningioma

MalaCards organs/tissues related to Skull Base Meningioma:

42
Bone, Pituitary, T Cells

Publications for Skull Base Meningioma

Articles related to Skull Base Meningioma:

(show top 50) (show all 58)
# Title Authors Year
1
Placement of cesium-131 permanent brachytherapy seeds using the endoscopic endonasal approach for recurrent anaplastic skull base meningioma: case report and technical note. ( 30835687 )
2019
2
EQ-5D Quality-of-Life Analysis and Cost-Effectiveness After Skull Base Meningioma Resection. ( 30869135 )
2019
3
Pseudobulbar Affect Due to Skull Base Meningioma Resolving After Temporal Lobectomy for Epilepsy. ( 29747704 )
2018
4
Spontaneous regression of a large skull base meningioma: case report. ( 29334772 )
2018
5
Influence of <sup>68</sup>Ga-DOTATOC on sparing of normal tissue for radiation therapy of skull base meningioma: differential impact of photon and proton radiotherapy. ( 29606149 )
2018
6
Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma. ( 29606047 )
2018
7
Introduction. Skull base meningioma treatment strategies. ( 29606055 )
2018
8
Skull base versus non-skull base meningioma surgery in the elderly. ( 29978438 )
2018
9
A rare case of diffuse intracranial aspergillosis masquerading as skull base meningioma in an immunocompetent patient. ( 30232959 )
2018
10
Fractionated Gamma Knife Radiosurgery as Initial Treatment for Large Skull Base Meningioma. ( 30022876 )
2018
11
Progesterone Receptor Is Responsible for Benign Biology of Skull Base Meningioma. ( 30031954 )
2018
12
Boron Neutron Capture Therapy for High-Grade Skull-Base Meningioma. ( 30210985 )
2018
13
One-step CAD/CAM titanium cranioplasty after drilling template-assisted resection of intraosseous skull base meningioma: technical note. ( 28074281 )
2017
14
Letter to the Editor. Neuropsychological impairment and quality of life after skull base meningioma resection: size and location matter. ( 28960157 )
2017
15
Frozen Section Can &amp;quot;Sharpen&amp;quot; or &amp;quot;Sand Off&amp;quot; the Surgeon's Knife: 2 Case Illustrations with Skull Base Meningioma Mimics. ( 28842226 )
2017
16
The extended, transnasal, transsphenoidal approach for anterior skull base meningioma: considerations in patient selection. ( 28689230 )
2017
17
Evaluation of Venous Drainage Patterns for Skull Base Meningioma Surgery. ( 28579577 )
2017
18
Lessons learned from reirradiation of recurrent skull base meningioma: A case report and review of the literature. ( 28740909 )
2017
19
Volume-staged gamma knife surgery for the treatment of large skull base meningioma surrounding the optical apparatus: A snowman-shape design. ( 28751167 )
2017
20
The Extended Subfrontal and Fronto-Orbito-Zygomatic Approach in Skull Base Meningioma Surgery: Clinical, Radiologic, and Cosmetic Outcome. ( 26825741 )
2016
21
Microsurgical resection of skull base meningioma-expanding the operative corridor. ( 27439458 )
2016
22
Rectal carcinoid tumor metastasis to a skull base meningioma. ( 26825133 )
2016
23
Radiation-induced anaplastic ependymoma mimicking a skull base meningioma: A case report. ( 26893630 )
2016
24
Case report: Epicranial pain after radiotherapy for skull base meningioma - the first symptomatic epicrania fugax? ( 27036640 )
2016
25
Safety and efficacy of medium-sized particle embolisation for skull-base meningioma. ( 26791376 )
2016
26
A neuro-oncologic challenge: the case of a large, aggressive, malignant meningioma of the skull base with paranasal sinus involvement. ( 26481862 )
2016
27
A rare case of atypical skull base meningioma with perineural spread. ( 27200171 )
2015
28
Ocular Neuromyotonia Noted after Recent Botulinum Toxin Injection for Sixth Nerve Palsy Following Resection of a Posterior Fossa Skull Base Meningioma. ( 27928330 )
2015
29
Minimal invasive trans-eyelid approach to anterior and middle skull base meningioma: a preliminary study of Shanghai Huashan hospital. ( 25550905 )
2014
30
A case of recurrent anaplastic meningioma of the skull base with radiologic response to hydroxyurea. ( 25083390 )
2014
31
Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model. ( 23460320 )
2013
32
5-Aminolevulinic Acid and (18)F-FET-PET as Metabolic Imaging Tools for Surgery of a Recurrent Skull Base Meningioma. ( 24436914 )
2013
33
A rare case of large skull base meningioma mimicking otitis media with effusion. ( 24454401 )
2013
34
The 'double pituitary hot spot' sign of skull base meningioma on gallium-68-labelled somatostatin analogue PET. ( 24283556 )
2013
35
A Comparative Study of Stereotactic Radiosurgery, Hypofractionated, and Fractionated Stereotactic Radiotherapy in the Treatment of Skull Base Meningioma. ( 23241504 )
2012
36
Delayed vasospasm after removal of a skull base meningioma. ( 21104584 )
2012
37
What is the best approach to resect an anterior midline skull base meningioma in 2011? Microsurgical transcranial, endonasal endoscopic, or minimal access cranial? ( 22120227 )
2012
38
An unusual nasal polyp: skull base meningioma with extracranial extension into the nasal cavity. ( 22241410 )
2012
39
Predicting postoperative hydrocephalus in 227 patients with skull base meningioma. ( 21529180 )
2011
40
Subacute brainstem necrosis: a complication of stereotactic radiotherapy for skull base meningioma. ( 21150684 )
2011
41
Analysis of factors affecting the long-term functional outcome of patients with skull base meningioma. ( 21565513 )
2011
42
Skull base meningioma - comparison of intensity-modulated radiotherapy planning techniques using the moduleaf micro-multileaf collimator and helical tomotherapy. ( 20171061 )
2010
43
The role of radical microsurgical resection in multimodal treatment for skull base meningioma. ( 20225926 )
2010
44
Balloon-assisted embolization of skull base meningioma with liquid embolic agent. ( 19361255 )
2010
45
Stereotactic radiosurgery for skull base meningioma. ( 19855141 )
2009
46
ABC Surgical Risk Scale for skull base meningioma: a new scoring system for predicting the extent of tumor removal and neurological outcome. Clinical article. ( 19119879 )
2009
47
Gamma Knife radiosurgery for skull base meningioma: long-term results of low-dose treatment. ( 18976068 )
2008
48
Patterns of skull base meningioma progression after failed radiosurgery. ( 17236485 )
2007
49
Impact of anomalous origin of the ophthalmic artery from the middle meningeal artery on selection of surgical approach to skull base meningioma. ( 17961750 )
2007
50
A canine case of skull base meningioma treated with hydroxyurea. ( 18176033 )
2007

Variations for Skull Base Meningioma

Expression for Skull Base Meningioma

Search GEO for disease gene expression data for Skull Base Meningioma.

Pathways for Skull Base Meningioma

GO Terms for Skull Base Meningioma

Biological processes related to Skull Base Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 receptor-mediated endocytosis GO:0006898 8.96 TMPRSS3 TMPRSS4
2 cellular response to cAMP GO:0071320 8.62 AKAP9 WT1

Molecular functions related to Skull Base Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type peptidase activity GO:0008236 8.96 TMPRSS3 TMPRSS4
2 scavenger receptor activity GO:0005044 8.62 TMPRSS3 TMPRSS4

Sources for Skull Base Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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