MCID: SKL005
MIFTS: 27

Skull Base Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Skull Base Meningioma

MalaCards integrated aliases for Skull Base Meningioma:

Name: Skull Base Meningioma 12 15 71
Meningioma of the Skull Base 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4437
NCIt 49 C5272
UMLS 71 C1335976

Summaries for Skull Base Meningioma

MalaCards based summary : Skull Base Meningioma, also known as meningioma of the skull base, is related to spinal meningioma and secretory meningioma, and has symptoms including seizures and headache. An important gene associated with Skull Base Meningioma is WT1 (WT1 Transcription Factor). The drug Edotreotide has been mentioned in the context of this disorder. Affiliated tissues include bone, brain and prostate.

Related Diseases for Skull Base Meningioma

Diseases in the Skull Base Meningioma family:

Multiple Skull Base Meningioma

Diseases related to Skull Base Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 158)
# Related Disease Score Top Affiliating Genes
1 spinal meningioma 31.2 TRAF7 PGR NF2
2 secretory meningioma 31.1 TRAF7 SERPINA3 NF2 KLF4
3 meningioma, radiation-induced 31.0 SST PGR NF2
4 olfactory groove meningioma 30.8 TRAF7 NF2
5 brain meningioma 30.7 TRAF7 NF2
6 neurilemmoma of the fifth cranial nerve 30.4 NT5C3A NF2
7 cranial nerve palsy 30.3 NT5C3A CCDC174
8 rare tumor 30.3 SST NF2
9 facial paralysis 30.2 NT5C3A NF2
10 meningothelial meningioma 29.7 TRAF7 SERPINA3 PGR NF2
11 benign meningioma 29.6 TRAF7 PGR NF2
12 clear cell meningioma 29.6 TRAF7 PGR NF2
13 meningioma, familial 28.1 TRAF7 SSTR2 SST SERPINA3 PGR OR5AC2
14 multiple skull base meningioma 12.7
15 lymphoplasmacyte-rich meningioma 11.0
16 benign mesothelioma 10.5 WT1 TRAF7
17 pediatric meningioma 10.5 TRAF7 NF2
18 peripheral nerve schwannoma 10.4 SERPINA3 NF2
19 intraventricular meningioma 10.4 TRAF7 NF2
20 psammomatous meningioma 10.4 TRAF7 NF2
21 anterior cranial fossa meningioma 10.4 TRAF7 NF2
22 intraneural perineurioma 10.4 TRAF7 NF2
23 trigeminal nerve neoplasm 10.4 NT5C3A NF2
24 rhabdoid meningioma 10.4 TRAF7 NF2
25 proliferative type fibrocystic change of breast 10.4 SERPINA3 EXTL1
26 fibrous meningioma 10.4 TRAF7 NF2
27 non-proliferative fibrocystic change of the breast 10.4 SERPINA3 EXTL1
28 optic nerve sheath meningioma 10.4 SCRT1 NF2
29 rare surgical neurologic disease 10.4
30 optic nerve neoplasm 10.3 SCRT1 NF2
31 peritoneum cancer 10.3 WT1 NF2
32 cranial nerve neoplasm 10.3 SCRT1 NF2
33 facial nerve disease 10.3 NT5C3A NF2
34 pediatric ependymoma 10.2 NF2 EXTL1
35 spindle cell sarcoma 10.2 SERPINA3 NF2
36 pancreatoblastoma 10.2 SST SERPINA3
37 hydrocephalus 10.2
38 hyperostosis 10.2
39 exophthalmos 10.2
40 pineal region meningioma 10.2 SSTR2 SCRT1
41 petroclival meningioma 10.1 TRAF7 NT5C3A EXTL1
42 functionless pituitary adenoma 10.1 SSTR2 SST
43 pancreatic gastrinoma 10.1 SSTR2 SST
44 gastrointestinal neuroendocrine tumor 10.1 SSTR2 SST
45 carcinoid tumors, intestinal 10.1 SSTR2 SST
46 hormone producing pituitary cancer 10.1 SSTR2 SST
47 pulmonary neuroendocrine tumor 10.1 SSTR2 SST
48 cervical serous adenocarcinoma 10.1 WT1 PGR
49 ovarian seromucinous carcinoma 10.1 WT1 PGR
50 contractures, pterygia, and variable skeletal fusions syndrome 1a 10.1 SST SERPINA3 NF2

Graphical network of the top 20 diseases related to Skull Base Meningioma:



Diseases related to Skull Base Meningioma

Symptoms & Phenotypes for Skull Base Meningioma

UMLS symptoms related to Skull Base Meningioma:


seizures, headache

Drugs & Therapeutics for Skull Base Meningioma

Drugs for Skull Base Meningioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Edotreotide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Hippocampal Sparing on Neurocognitive Functions and Quality of Live in Patients Irradiated in the Neurocranial Area Recruiting NCT01849484 Phase 2
2 Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery -Randomized Prospective Trial Unknown status NCT02084927 Phase 1
3 Randomized Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial. Not yet recruiting NCT01795300

Search NIH Clinical Center for Skull Base Meningioma

Genetic Tests for Skull Base Meningioma

Anatomical Context for Skull Base Meningioma

MalaCards organs/tissues related to Skull Base Meningioma:

40
Bone, Brain, Prostate, T Cells, Pituitary

Publications for Skull Base Meningioma

Articles related to Skull Base Meningioma:

(show top 50) (show all 153)
# Title Authors PMID Year
1
Acute Vision Loss After Ophthalmic Artery Embolization of Meningioma. 61
30893270 2019
2
Skull base versus non-skull base meningioma surgery in the elderly. 61
29978438 2019
3
High Mib-1-score correlates with new cranial nerve deficits after surgery for frontal skull base meningioma. 61
31834543 2019
4
Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis. 61
31718650 2019
5
Feasibility of Bundled Payments in Anterior, Middle, and Posterior Cranial Fossa Skull Base Meningioma Surgery: MarketScan Analysis of Health Care Utilization and Outcomes. 61
31323403 2019
6
Preliminary experience with a digital robotic exoscope in cranial and spinal surgery: a review of the Synaptive Modus V system. 61
31119395 2019
7
Efficacy and Tolerance of Intensity Modulated Radiation Therapy for Skull Base Meningioma. 61
31673652 2019
8
Pneumosinus Dilatans: An exploration into the association between Arachnoid Cyst, Meningioma and the pathogenesis of Pneumosinus Dilatans. 61
31445325 2019
9
EQ-5D Quality-of-Life Analysis and Cost-Effectiveness After Skull Base Meningioma Resection. 61
30869135 2019
10
New insights into the genomic landscape of meningiomas identified FGFR3 in a subset of patients with favorable prognoses. 61
31565188 2019
11
Early Postoperative Complications in Meningioma: Predictive Factors and Impact on Outcome. 61
31082552 2019
12
[Skull base meningioma: Clinical and radiological efficacy based on a quantitative volumetric analysis]. 61
31128988 2019
13
Multisession radiosurgery for perioptic meningiomas: medium-to-long term results from a CyberKnife cooperative study. 61
31119480 2019
14
Implications of Extracranial Distortion in Ultra-High-Field Magnetic Resonance Imaging for Image-Guided Cranial Neurosurgery. 61
30797931 2019
15
Occipital to Angular Artery Bypass for Post-irradiation Ischemia: 3-Dimensional Operative Video. 61
31173139 2019
16
The Natural Growth Rate of Skull Base Meningiomas Compared With Non-Skull Base Meningiomas. 61
30908440 2019
17
Resection of a Dumbbell Skull Base Meningioma by a Combined Two-Staged Retrosigmoid and Transzygomatic Transcavernous Approach. 61
31143600 2019
18
Risk group-adapted adjuvant radiotherapy for WHO grade I and II skull base meningioma. 61
30953136 2019
19
Cranial Nerve Outcomes After Surgery for Frontal Skull Base Meningiomas: The Eternal Quest of the Maximum-Safe Resection with the Lowest Morbidity. 61
30738945 2019
20
Placement of cesium-131 permanent brachytherapy seeds using the endoscopic endonasal approach for recurrent anaplastic skull base meningioma: case report and technical note. 61
30835687 2019
21
Lessons learned in the evolution of endoscopic skull base surgery. 61
30717035 2019
22
Metastatic Gallbladder Carcinoma in Meningioma: A Case Report. 61
28731197 2019
23
A rare case of diffuse intracranial aspergillosis masquerading as skull base meningioma in an immunocompetent patient. 61
30232959 2019
24
Correlation of Preoperative Radiological Evaluation of Skull Base and Non-skull Base Meningiomas with Clinical and Surgical Data. 61
30649817 2019
25
Endoscopic endonasal approaches for the management of skull base meningiomas: selection criteria and clinical outcomes. 61
29808635 2018
26
Red Blood Cell Transfusions Following Resection of Skull Base Meningiomas: Risk Factors and Clinical Outcomes. 61
30456031 2018
27
Olfactory groove and tuberculum sellae meningioma resection by endoscopic endonasal approach versus transcranial approach: A systematic review and meta-analysis of comparative studies. 61
30193170 2018
28
Surgical outcomes after reoperation for recurrent non-skull base meningiomas. 61
30544357 2018
29
Moulded Osteomyofascial Pedicled Split (MOPS) Craniotomy Flap in Reconstruction of Anterior Cranial Fossa Defects: Pilot Study of a Novel Technique. 61
30459859 2018
30
Successful Treatment of Pneumocephalus Using a Free-Style Chimeric Free Flap From a Scarred Thigh. 61
29944558 2018
31
Three-dimensional multimodality fusion imaging as an educational and planning tool for deep-seated meningiomas. 61
29943649 2018
32
The Endoscopic Endonasal Management of Anterior Skull Base Meningiomas. 61
30210982 2018
33
Progesterone Receptor Is Responsible for Benign Biology of Skull Base Meningioma. 61
30031954 2018
34
Boron Neutron Capture Therapy for High-Grade Skull-Base Meningioma. 61
30210985 2018
35
Stereotactic radiosurgery for benign brain tumors: Results of multicenter benchmark planning studies. 61
29884596 2018
36
Preoperative Embolization of Skull Base Meningiomas: Outcomes in the Onyx Era. 61
29751190 2018
37
Pseudobulbar Affect Due to Skull Base Meningioma Resolving After Temporal Lobectomy for Epilepsy. 61
29747704 2018
38
Fractionated Gamma Knife Radiosurgery as Initial Treatment for Large Skull Base Meningioma. 61
30022876 2018
39
[Base of the skull meningioma: Efficacy, clinical tolerance and radiological evaluation after radiotherapy]. 61
29773473 2018
40
Case report: Wallenberg's syndrome, a possible cause of symptomatic epicrania fugax. 61
28786694 2018
41
Incidence, Clinico-Radiological Features and Outcome of Skull Base versus Non-Skull Base Meningiomas Treated in Kuala Lumpur General Hospital: A Five-Year Experience. 61
30899190 2018
42
Dural Closure in Confined Spaces of the Skull Base with Nonpenetrating Titanium Clips. 61
28973649 2018
43
Multivariate risk factor analysis and literature review of postoperative deterioration in Karnofsky Performance Scale score in elderly patients with skull base meningioma. 61
29606047 2018
44
Influence of 68Ga-DOTATOC on sparing of normal tissue for radiation therapy of skull base meningioma: differential impact of photon and proton radiotherapy. 61
29606149 2018
45
Introduction. Skull base meningioma treatment strategies. 61
29606055 2018
46
Clinical outcome after particle therapy for meningiomas of the skull base: toxicity and local control in patients treated with active rasterscanning. 61
29587795 2018
47
Efficiency and Safety of Autologous Fat Grafts in Reconstructing Skull Base Defects After Resection of Skull Base Meningiomas. 61
29174239 2018
48
[The curative effect analysis of unilateral subfrontal combined with interhemispheric approach on the microsurgery of large anterior skull base meningioma]. 61
29495222 2018
49
Spontaneous regression of a large skull base meningioma: case report. 61
29334772 2018
50
Letter to the Editor. Neuropsychological impairment and quality of life after skull base meningioma resection: size and location matter. 61
28960157 2017

Variations for Skull Base Meningioma

Expression for Skull Base Meningioma

Search GEO for disease gene expression data for Skull Base Meningioma.

Pathways for Skull Base Meningioma

GO Terms for Skull Base Meningioma

Biological processes related to Skull Base Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.02 WT1 SSTR2 SST NF2 KLF4

Sources for Skull Base Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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