MCID: SKL006
MIFTS: 20

Skull Base Neoplasm

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Skull Base Neoplasm

MalaCards integrated aliases for Skull Base Neoplasm:

Name: Skull Base Neoplasm 12 15
Skull Base Neoplasms 44 73
Tumors of Skull Base 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3842
MeSH 44 D019292
NCIt 50 C4676
UMLS 73 C0376527

Summaries for Skull Base Neoplasm

MalaCards based summary : Skull Base Neoplasm, also known as skull base neoplasms, is related to facial paralysis and intracranial sinus thrombosis. An important gene associated with Skull Base Neoplasm is CCDC174 (Coiled-Coil Domain Containing 174). The drugs Aminolevulinic acid and Dermatologic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and bone.

Related Diseases for Skull Base Neoplasm

Diseases related to Skull Base Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 facial paralysis 9.9
2 intracranial sinus thrombosis 9.3 BLVRA NT5C3A
3 petroclival meningioma 7.9 BLVRA KRT83 NT5C3A TMPRSS4
4 skull base meningioma 7.6 AKAP9 BLVRA CCDC174 KRT83 NT5C3A

Symptoms & Phenotypes for Skull Base Neoplasm

Drugs & Therapeutics for Skull Base Neoplasm

Drugs for Skull Base Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aminolevulinic acid Approved Phase 1 106-60-5 137
2 Dermatologic Agents Phase 1
3 Photosensitizing Agents Phase 1
4 Anesthetics Not Applicable
5 Central Nervous System Depressants Not Applicable
6 Hemostatics Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fluorescence Guided Resection of Brain Tumors Completed NCT00870779 Phase 1 5-aminolevulinic acid
2 ICG Use in Angiography for Nasoseptal Flap Harvest Completed NCT02117310 Not Applicable indocyanine green
3 Barrow Nasal Inventory Survey Completed NCT01322945
4 Effects on the Awakening With Laryngeal Mask vs Endotracheal Tube in Endoscopic Endonasal Transsphenoidal Base Surgery Recruiting NCT02988804 Not Applicable
5 Cranial Nerves Tractography Recruiting NCT02978911 Not Applicable
6 In-Room PET in Proton Radiation Therapy Recruiting NCT01228448 Not Applicable
7 Improvement of Outcomes in Draf III/Endoscopic Modified Lothrop Procedure Recruiting NCT02981017 Not Applicable
8 Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes Recruiting NCT01200680
9 Skull Base Reconstruction After Endonasal Cranio-endoscopic Resection Using Autologus Grafts Active, not recruiting NCT03448614

Search NIH Clinical Center for Skull Base Neoplasm

Cochrane evidence based reviews: skull base neoplasms

Genetic Tests for Skull Base Neoplasm

Anatomical Context for Skull Base Neoplasm

MalaCards organs/tissues related to Skull Base Neoplasm:

41
Brain, Bone

Publications for Skull Base Neoplasm

Articles related to Skull Base Neoplasm:

# Title Authors Year
1
Facial paralysis caused by malignant skull base neoplasms. ( 16119900 )
2002
2
Facial paralysis caused by malignant skull base neoplasms. ( 12516381 )
2002
3
Education and information needs identified by patients and key family members prior to surgery for a skull base neoplasm: implications for practice. ( 11901493 )
2000

Variations for Skull Base Neoplasm

Expression for Skull Base Neoplasm

Search GEO for disease gene expression data for Skull Base Neoplasm.

Pathways for Skull Base Neoplasm

GO Terms for Skull Base Neoplasm

Sources for Skull Base Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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