MCID: SML003
MIFTS: 24

Small Cell Osteogenic Sarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Small Cell Osteogenic Sarcoma

MalaCards integrated aliases for Small Cell Osteogenic Sarcoma:

Name: Small Cell Osteogenic Sarcoma 12 15
Small Cell Osteosarcoma 12 71
Round Cell Osteosarcoma 12
Osteosarcoma Small Cell 54

Classifications:



External Ids:

Disease Ontology 12 DOID:3377
NCIt 49 C4023
SNOMED-CT 67 12302002
UMLS 71 C0279622

Summaries for Small Cell Osteogenic Sarcoma

MalaCards based summary : Small Cell Osteogenic Sarcoma, also known as small cell osteosarcoma, is related to connective tissue benign neoplasm and ewing sarcoma, and has symptoms including pain An important gene associated with Small Cell Osteogenic Sarcoma is ENO2 (Enolase 2). Affiliated tissues include bone, spinal cord and liver.

Related Diseases for Small Cell Osteogenic Sarcoma

Diseases related to Small Cell Osteogenic Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 connective tissue benign neoplasm 29.9 EWSR1 ENO2
2 ewing sarcoma 29.9 EWSR1 ENO2 CD99 CCNB3 BCOR
3 small cell sarcoma 28.3 EWSR1 DUX4L8 DUX4L7 CCNB3 BCOR
4 sarcoma, synovial 27.9 EWSR1 DUX4L8 DUX4L7 CD99 CCNB3 BCOR
5 bone osteosarcoma 26.9 SNRNP25 MIR7850 MIR6859-1 MIR6842 MIR5706 EWSR1
6 cauda equina neoplasm 10.4 EWSR1 ENO2
7 cerebellopontine angle primitive neuroectodermal tumor 10.4 ENO2 CD99
8 retroperitoneal neuroblastoma 10.4 ENO2 CD99
9 cervical neuroblastoma 10.4 EWSR1 ENO2
10 extraskeletal mesenchymal chondrosarcoma 10.4 EWSR1 CD99
11 extracranial neuroblastoma 10.3 EWSR1 ENO2
12 ectomesenchymoma 10.3 ENO2 CD99
13 endobronchial lipoma 10.3 EWSR1 ENO2
14 sarcomatosis 10.3 EWSR1 CREB3L1
15 central nervous system primitive neuroectodermal neoplasm 10.3 ENO2 CD99
16 rhabdoid cancer 10.3 EWSR1 BCOR
17 malignant teratoma 10.3 ENO2 CD99
18 intracranial primitive neuroectodermal tumor 10.2 EWSR1 ENO2 CD99
19 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.2 EWSR1 ENO2 CD99
20 ewing sarcoma of bone 10.2 EWSR1 ENO2 CD99
21 central nervous system mesenchymal non-meningothelial tumor 10.2 EWSR1 ENO2 CD99
22 extraskeletal ewing sarcoma 10.2 EWSR1 ENO2 CD99
23 extraosseous ewing sarcoma 10.2 EWSR1 ENO2 CD99
24 olfactory nerve neoplasm 10.2 EWSR1 ENO2 CD99
25 cranial nerve malignant neoplasm 10.2 EWSR1 ENO2 CD99
26 cranial nerve neoplasm 10.2 EWSR1 ENO2 CD99
27 olfactory neuroblastoma 10.2 EWSR1 ENO2 CD99
28 skeletal muscle cancer 10.2 EWSR1 ENO2 CD99
29 muscle cancer 10.2 EWSR1 ENO2 CD99
30 chondrosarcoma 10.2
31 mesenchymal chondrosarcoma 10.2
32 pineal gland cancer 10.2 ENO2 BCOR
33 hemangiopericytoma, malignant 10.2 ENO2 CD99
34 cellular congenital mesoblastic nephroma 10.2 CCNB3 BCOR
35 osteogenic sarcoma 10.2
36 congenital mesoblastic nephroma 10.2 CCNB3 BCOR
37 congenital fibrosarcoma 10.1 EWSR1 CCNB3
38 astroblastoma 10.1 ENO2 BCOR
39 juxtacortical osteosarcoma 10.1 SNRNP25 EWSR1
40 kidney cortex disease 10.1 CCNB3 BCOR
41 peripheral osteosarcoma 10.1 SNRNP25 EWSR1
42 ossifying fibromyxoid tumor 10.0 ENO2 CCNB3 BCOR
43 ganglioneuroma 10.0 ENO2 CD99
44 sarcoma 10.0
45 spindle cell sarcoma 10.0
46 kidney sarcoma 10.0 EWSR1 CCNB3 BCOR
47 pediatric fibrosarcoma 10.0 EWSR1 CCNB3 BCOR
48 mesenchymal cell neoplasm 10.0 EWSR1 CCNB3 BCOR
49 endometrial stromal tumor 10.0 EWSR1 CCNB3 BCOR
50 extraosseous osteosarcoma 10.0

Graphical network of the top 20 diseases related to Small Cell Osteogenic Sarcoma:



Diseases related to Small Cell Osteogenic Sarcoma

Symptoms & Phenotypes for Small Cell Osteogenic Sarcoma

UMLS symptoms related to Small Cell Osteogenic Sarcoma:


pain

Drugs & Therapeutics for Small Cell Osteogenic Sarcoma

Search Clinical Trials , NIH Clinical Center for Small Cell Osteogenic Sarcoma

Genetic Tests for Small Cell Osteogenic Sarcoma

Anatomical Context for Small Cell Osteogenic Sarcoma

MalaCards organs/tissues related to Small Cell Osteogenic Sarcoma:

40
Bone, Spinal Cord, Liver

Publications for Small Cell Osteogenic Sarcoma

Articles related to Small Cell Osteogenic Sarcoma:

(show top 50) (show all 97)
# Title Authors PMID Year
1
[Pathologic diagnosis of primary small round cell tumors of the bone]. 54 61
12920805 2003
2
An EWSR1-CREB3L1 Fusion Gene in Extraskeletal Undifferentiated Round Cell Sarcoma Expands the Spectrum of Genetic Landscape in the "Ewing-Like" Undifferentiated Round Cell Sarcomas. 61
32506986 2020
3
SATB2 and TLE1 Expression in BCOR-CCNB3 (Ewing-like) Sarcoma, Mimicking Small Cell Osteosarcoma and Poorly Differentiated Synovial Sarcoma. 61
29084055 2020
4
Ewing sarcoma and Ewing-like tumors. 61
31802230 2020
5
Endobronchial metastasis as an uncommon pattern of metastatic dissemination from small cell osteosarcoma. 61
31366615 2019
6
Small round cell lesions of the bone: Diagnostic approach, differential diagnoses and impact on treatment. 61
30971540 2019
7
Laryngeal sarcomas: A case series of 5 cases. 61
30241033 2018
8
A Comparison of the Histopathologic Growth Patterns Between Non-Merkel Cell Small Round Blue Cell Tumors and Merkel Cell Carcinoma. 61
30045067 2018
9
PAX7 immunohistochemical evaluation of Ewing sarcoma and other small round cell tumours. 61
29920735 2018
10
Ewing Sarcoma and the History of Similar and Possibly Related Small Round Cell Tumors: From Whence Have We Come and Where are We Going? 61
29911999 2018
11
Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information. 61
29572501 2018
12
Osteosarcoma of the jaws in Koreans: analysis of 26 cases. 61
29142865 2017
13
Identification of the miRNA-mRNA regulatory network of small cell osteosarcoma based on RNA-seq. 61
28477009 2017
14
Small round blue cell tumors of the sinonasal tract: a differential diagnosis approach. 61
28060373 2017
15
The utility of SATB2 immunohistochemical expression in distinguishing between osteosarcomas and their malignant bone tumor mimickers, such as Ewing sarcomas and chondrosarcomas. 61
27465835 2016
16
Establishment and Characterization of a Human Small Cell Osteosarcoma Cancer Stem Cell Line: A New Possible In Vitro Model for Discovering Small Cell Osteosarcoma Biology. 61
27651797 2016
17
Small cell osteosarcoma of the parietal region: a unique case at an unusual site. 61
26628304 2015
18
Small cell osteosarcoma: clinicopathologic, immunohistochemical, and molecular analysis of 36 cases. 61
25723116 2015
19
Cytological diagnosis of small cell osteosarcoma of the bone. 61
26229255 2015
20
Utility of transmission electron microscopy in small round cell tumors. 61
25812730 2015
21
[Bone tumours in lizards and snakes. A rare clinical finding]. 61
25609210 2015
22
Round cell tumors of bone: an update on recent molecular genetic advances. 61
25105937 2014
23
Metastatic small cell osteosarcoma to the liver: a diagnostic pitfall for fine-needle aspiration cytology. 61
22865770 2014
24
Small cell extraskeletal osteosarcoma: a rare case report. 61
24711902 2014
25
Osteogenic tumors of bone. 61
24680179 2014
26
Contralateral referred pain in a patient with intramedullary spinal cord metastasis from extraskeletal small cell osteosarcoma. 61
24090113 2013
27
Small cell osteosarcoma with Ewing sarcoma breakpoint region 1 gene rearrangement detected by interphase fluorescence in situ hybridization. 61
22971270 2013
28
The role of immunohistochemistry in the analysis of the spectrum of small round cell tumours at a tertiary care centre. 61
23998069 2013
29
Galectin-1 (GAL-1) expression is a useful tool to differentiate between small cell osteosarcoma and Ewing sarcoma. 61
23681112 2013
30
[Small cell malignant tumors of bone: comparison between diagnosis using core needle biopsies and surgical specimens]. 61
23769434 2013
31
Osteosarcoma of the femur mimicking Ewing sarcoma/primitive neuroectodermal tumour on biopsy and metastatic carcinoma on resection. 61
22565380 2012
32
Small cell osteosarcoma successfully treated by high-dose ifosfamide and methotrexate, combined with carboplatin and pirarubicin. 61
22399618 2012
33
Small cell osteosarcoma of rib: diagnosis and treatment of the rare case. 61
22779940 2012
34
A novel EWSR1-CREB3L1 fusion transcript in a case of small cell osteosarcoma. 61
21987447 2011
35
Small cell osteosarcoma of the mandible: Case report and review of its diagnostic aspects. 61
22144840 2011
36
FLI-1 distinguishes Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma. 61
21084965 2011
37
Histopathological characterization of small cell osteosarcoma with immunohistochemistry and molecular genetic support. A study of 10 cases. 61
20557371 2010
38
Small cell osteosarcoma of a toe phalanx: a case report and review of literature. 61
20525255 2010
39
Small cell osteosarcoma: cytopathologic characteristics and differential diagnosis. 61
20395522 2010
40
Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and beta-catenin, Sox9, and osteocalcin immunostaining of 22 cases. 61
20138330 2010
41
Small cell tumors of bone. 61
20032633 2010
42
Small cell osteosarcoma: a case report. 61
19886558 2009
43
Malignant small round cell tumors. 61
21938141 2009
44
Small round cell tumors of bone. 61
17284103 2007
45
Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcoma. 61
16596382 2006
46
Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma. 61
16328381 2006
47
"Undifferentiated" small round cell tumors of the sinonasal tract: differential diagnosis update. 61
16468421 2005
48
Cytogenetic and spectral karyotype analyses of benign and malignant cartilage tumours. 61
15138578 2004
49
Abdominal small round cell tumor with osteoid and EWS/FLI1. 61
15188147 2004
50
Electron microscopy and other ancillary techniques in the diagnosis of small round cell tumors. 61
12693673 2003

Variations for Small Cell Osteogenic Sarcoma

Expression for Small Cell Osteogenic Sarcoma

Search GEO for disease gene expression data for Small Cell Osteogenic Sarcoma.

Pathways for Small Cell Osteogenic Sarcoma

GO Terms for Small Cell Osteogenic Sarcoma

Biological processes related to Small Cell Osteogenic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of sprouting angiogenesis GO:1903671 8.62 MIR221 CREB3L1

Sources for Small Cell Osteogenic Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....