MCID: SML003
MIFTS: 24

Small Cell Osteogenic Sarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Small Cell Osteogenic Sarcoma

MalaCards integrated aliases for Small Cell Osteogenic Sarcoma:

Name: Small Cell Osteogenic Sarcoma 12 15
Small Cell Osteosarcoma 12 72
Round Cell Osteosarcoma 12
Osteosarcoma Small Cell 55

Classifications:



External Ids:

Disease Ontology 12 DOID:3377
NCIt 50 C4023
SNOMED-CT 68 12302002
UMLS 72 C0279622

Summaries for Small Cell Osteogenic Sarcoma

MalaCards based summary : Small Cell Osteogenic Sarcoma, also known as small cell osteosarcoma, is related to chondrosarcoma and bone osteosarcoma, and has symptoms including pain An important gene associated with Small Cell Osteogenic Sarcoma is ENO2 (Enolase 2). Affiliated tissues include bone, liver and spinal cord.

Related Diseases for Small Cell Osteogenic Sarcoma

Diseases related to Small Cell Osteogenic Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 chondrosarcoma 30.3 EWSR1 ENO2
2 bone osteosarcoma 30.2 SATB2 BCOR
3 askin's tumor 29.8 EWSR1 ENO2
4 ewing sarcoma 29.8 EWSR1 ENO2 BCOR
5 mesenchymal chondrosarcoma 10.2
6 osteogenic sarcoma 10.2
7 mucinous ovarian cystadenoma 10.1 SATB2 ENO2
8 cauda equina neoplasm 10.1 EWSR1 ENO2
9 kidney rhabdoid cancer 10.1 EWSR1 ENO2
10 extraosseous chondrosarcoma 10.0 EWSR1 ENO2
11 intraocular retinoblastoma 10.0 SATB2 ENO2
12 desmoplastic small round cell tumor 10.0 EWSR1 ENO2
13 sarcoma 10.0
14 spindle cell sarcoma 10.0
15 extraskeletal ewing sarcoma 10.0 EWSR1 ENO2
16 sarcomatosis 10.0 EWSR1 CREB3L1
17 kidney fibrosarcoma 10.0 EWSR1 CREB3L1
18 olfactory neuroblastoma 9.9 EWSR1 ENO2
19 myeloid leukemia 9.9
20 chondrosarcoma, extraskeletal myxoid 9.9 EWSR1 ENO2
21 muscle cancer 9.9 EWSR1 ENO2
22 connective tissue cancer 9.8 EWSR1 ENO2
23 sarcoma, synovial 9.8
24 aneurysmal bone cysts 9.8
25 lymphoma 9.8
26 connective tissue benign neoplasm 9.8
27 lymphoblastic lymphoma 9.8
28 osteomyelitis 9.8
29 papilledema 9.8
30 neuroendocrine carcinoma 9.8
31 giant cell tumor 9.8
32 small cell sarcoma 9.8
33 extraosseous osteosarcoma 9.8
34 intracortical osteogenic sarcoma 9.8
35 ewing's family of tumors 9.8
36 primary bone cancer 9.8
37 rhabdomyosarcoma 2 9.8 EWSR1 ENO2
38 kidney clear cell sarcoma 9.8 SATB2 ENO2 BCOR
39 rhabdoid cancer 9.7 EWSR1 ENO2 BCOR
40 nervous system cancer 9.7 EWSR1 ENO2
41 clear cell sarcoma 9.7 EWSR1 ENO2 BCOR
42 conventional central osteosarcoma 9.6 SATB2 EWSR1 BCOR
43 tooth agenesis 9.5 SATB2 BCOR

Graphical network of the top 20 diseases related to Small Cell Osteogenic Sarcoma:



Diseases related to Small Cell Osteogenic Sarcoma

Symptoms & Phenotypes for Small Cell Osteogenic Sarcoma

UMLS symptoms related to Small Cell Osteogenic Sarcoma:


pain

Drugs & Therapeutics for Small Cell Osteogenic Sarcoma

Search Clinical Trials , NIH Clinical Center for Small Cell Osteogenic Sarcoma

Genetic Tests for Small Cell Osteogenic Sarcoma

Anatomical Context for Small Cell Osteogenic Sarcoma

MalaCards organs/tissues related to Small Cell Osteogenic Sarcoma:

41
Bone, Liver, Spinal Cord

Publications for Small Cell Osteogenic Sarcoma

Articles related to Small Cell Osteogenic Sarcoma:

(show top 50) (show all 95)
# Title Authors PMID Year
1
[Pathologic diagnosis of primary small round cell tumors of the bone]. 9 38
12920805 2003
2
Endobronchial metastasis as an uncommon pattern of metastatic dissemination from small cell osteosarcoma. 38
31366615 2019
3
Small round cell lesions of the bone: Diagnostic approach, differential diagnoses and impact on treatment. 38
30971540 2019
4
Laryngeal sarcomas: A case series of 5 cases. 38
30241033 2018
5
A Comparison of the Histopathologic Growth Patterns Between Non-Merkel Cell Small Round Blue Cell Tumors and Merkel Cell Carcinoma. 38
30045067 2018
6
PAX7 immunohistochemical evaluation of Ewing sarcoma and other small round cell tumours. 38
29920735 2018
7
Ewing Sarcoma and the History of Similar and Possibly Related Small Round Cell Tumors: From Whence Have We Come and Where are We Going? 38
29911999 2018
8
Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information. 38
29572501 2018
9
Osteosarcoma of the jaws in Koreans: analysis of 26 cases. 38
29142865 2017
10
SATB2 and TLE1 Expression in BCOR-CCNB3 (Ewing-like) Sarcoma, Mimicking Small Cell Osteosarcoma and Poorly Differentiated Synovial Sarcoma. 38
29084055 2017
11
Identification of the miRNA-mRNA regulatory network of small cell osteosarcoma based on RNA-seq. 38
28477009 2017
12
Small round blue cell tumors of the sinonasal tract: a differential diagnosis approach. 38
28060373 2017
13
The utility of SATB2 immunohistochemical expression in distinguishing between osteosarcomas and their malignant bone tumor mimickers, such as Ewing sarcomas and chondrosarcomas. 38
27465835 2016
14
Establishment and Characterization of a Human Small Cell Osteosarcoma Cancer Stem Cell Line: A New Possible In Vitro Model for Discovering Small Cell Osteosarcoma Biology. 38
27651797 2016
15
Small cell osteosarcoma of the parietal region: a unique case at an unusual site. 38
26628304 2015
16
Small cell osteosarcoma: clinicopathologic, immunohistochemical, and molecular analysis of 36 cases. 38
25723116 2015
17
Cytological diagnosis of small cell osteosarcoma of the bone. 38
26229255 2015
18
Utility of transmission electron microscopy in small round cell tumors. 38
25812730 2015
19
[Bone tumours in lizards and snakes. A rare clinical finding]. 38
25609210 2015
20
Round cell tumors of bone: an update on recent molecular genetic advances. 38
25105937 2014
21
Metastatic small cell osteosarcoma to the liver: a diagnostic pitfall for fine-needle aspiration cytology. 38
22865770 2014
22
Osteogenic tumors of bone. 38
24680179 2014
23
Small cell extraskeletal osteosarcoma: a rare case report. 38
24711902 2014
24
Contralateral referred pain in a patient with intramedullary spinal cord metastasis from extraskeletal small cell osteosarcoma. 38
24090113 2013
25
Small cell osteosarcoma with Ewing sarcoma breakpoint region 1 gene rearrangement detected by interphase fluorescence in situ hybridization. 38
22971270 2013
26
The role of immunohistochemistry in the analysis of the spectrum of small round cell tumours at a tertiary care centre. 38
23998069 2013
27
Galectin-1 (GAL-1) expression is a useful tool to differentiate between small cell osteosarcoma and Ewing sarcoma. 38
23681112 2013
28
[Small cell malignant tumors of bone: comparison between diagnosis using core needle biopsies and surgical specimens]. 38
23769434 2013
29
Osteosarcoma of the femur mimicking Ewing sarcoma/primitive neuroectodermal tumour on biopsy and metastatic carcinoma on resection. 38
22565380 2012
30
Small cell osteosarcoma successfully treated by high-dose ifosfamide and methotrexate, combined with carboplatin and pirarubicin. 38
22399618 2012
31
Small cell osteosarcoma of rib: diagnosis and treatment of the rare case. 38
22779940 2012
32
A novel EWSR1-CREB3L1 fusion transcript in a case of small cell osteosarcoma. 38
21987447 2011
33
Small cell osteosarcoma of the mandible: Case report and review of its diagnostic aspects. 38
22144840 2011
34
FLI-1 distinguishes Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma. 38
21084965 2011
35
Histopathological characterization of small cell osteosarcoma with immunohistochemistry and molecular genetic support. A study of 10 cases. 38
20557371 2010
36
Small cell osteosarcoma of a toe phalanx: a case report and review of literature. 38
20525255 2010
37
Small cell osteosarcoma: cytopathologic characteristics and differential diagnosis. 38
20395522 2010
38
Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and beta-catenin, Sox9, and osteocalcin immunostaining of 22 cases. 38
20138330 2010
39
Small cell tumors of bone. 38
20032633 2010
40
Small cell osteosarcoma: a case report. 38
19886558 2009
41
Malignant small round cell tumors. 38
21938141 2009
42
Small round cell tumors of bone. 38
17284103 2007
43
Monoallelic deletion of the p53 gene through chromosomal translocation in a small cell osteosarcoma. 38
16596382 2006
44
Femoral mesenchymal chondrosarcoma with secondary aneurysmal bone cysts mimicking a small-cell osteosarcoma. 38
16328381 2006
45
"Undifferentiated" small round cell tumors of the sinonasal tract: differential diagnosis update. 38
16468421 2005
46
Cytogenetic and spectral karyotype analyses of benign and malignant cartilage tumours. 38
15138578 2004
47
Abdominal small round cell tumor with osteoid and EWS/FLI1. 38
15188147 2004
48
Electron microscopy and other ancillary techniques in the diagnosis of small round cell tumors. 38
12693673 2003
49
Fine needle aspiration cytology in the diagnosis and management of children and adolescents with Ewing sarcoma and peripheral primitive neuroectodermal tumor. 38
11835234 2002
50
Pathology quiz: small cell osteosarcoma. 38
11486738 2001

Variations for Small Cell Osteogenic Sarcoma

Expression for Small Cell Osteogenic Sarcoma

Search GEO for disease gene expression data for Small Cell Osteogenic Sarcoma.

Pathways for Small Cell Osteogenic Sarcoma

GO Terms for Small Cell Osteogenic Sarcoma

Biological processes related to Small Cell Osteogenic Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.13 SATB2 CREB3L1 BCOR
2 roof of mouth development GO:0060021 8.62 SATB2 BCOR

Sources for Small Cell Osteogenic Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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