MCID: SML039
MIFTS: 26

Small Intestine Benign Neoplasm

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Small Intestine Benign Neoplasm

MalaCards integrated aliases for Small Intestine Benign Neoplasm:

Name: Small Intestine Benign Neoplasm 12 15
Neoplasm of the Small Intestine 29
Neoplasm of Small Intestine 12
Small Intestinal Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:7505
NCIt 50 C4432
SNOMED-CT 67 126832004
UMLS 70 C0345832

Summaries for Small Intestine Benign Neoplasm

MalaCards based summary : Small Intestine Benign Neoplasm, also known as neoplasm of the small intestine, is related to small intestine leiomyoma and small intestine leiomyosarcoma. An important gene associated with Small Intestine Benign Neoplasm is HOOK3 (Hook Microtubule Tethering Protein 3), and among its related pathways/superpathways is C-MYB transcription factor network. Affiliated tissues include small intestine, and related phenotypes are growth/size/body region and nervous system

Related Diseases for Small Intestine Benign Neoplasm

Diseases related to Small Intestine Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 322)
# Related Disease Score Top Affiliating Genes
1 small intestine leiomyoma 31.9 KIT CD34 ANO1
2 small intestine leiomyosarcoma 31.0 KIT CD34 ANO1
3 small intestine neuroendocrine neoplasm 30.6 SST PNMA2 NONO MLF1 MIR3137 MEN1
4 rare tumor 30.6 SST KIT
5 neurilemmoma 29.5 KIT ENO2 CD34 ANO1
6 small intestine cancer 11.3
7 squamous cell carcinoma of the small intestine 10.6
8 type c thymoma 10.4 SST KIT
9 ectopic cushing syndrome 10.4 SST CHGA
10 rectum neuroendocrine neoplasm 10.4 SYP SST
11 glucagonoma 10.4 SST CHGA
12 primary hepatic neuroendocrine carcinoma 10.4 SYP CHGA
13 esophageal neuroendocrine tumor 10.4 SYP CHGA
14 acinar cell cystadenocarcinoma 10.3 SYP CHGA
15 vulvar eccrine porocarcinoma 10.3 SYP CHGA
16 pancreatic serous cystadenocarcinoma 10.3 SYP CHGA
17 vaginal tubulovillous adenoma 10.3 SYP CHGA
18 mixed ductal-endocrine carcinoma 10.3 SYP CHGA
19 papillary thymic adenocarcinoma 10.3 SYP CHGA
20 breast papillary carcinoma 10.3 SYP CHGA
21 appendix adenocarcinoma 10.3 SYP CHGA
22 gastric leiomyoma 10.3 KIT ANO1
23 gastric leiomyosarcoma 10.3 KIT ANO1
24 small intestinal sarcoma 10.3 KIT ANO1
25 pulmonary large cell neuroendocrine carcinoma 10.3 SYP CHGA
26 vaginal adenoma 10.3 SYP CHGA
27 duodenal somatostatinoma 10.3 SST MEN1
28 vaginal benign neoplasm 10.3 SYP CHGA
29 pituitary infarct 10.3 SST MEN1
30 mucinous stomach adenocarcinoma 10.3 KIT ANO1
31 chordoid meningioma 10.3 SYP CHGA
32 pancreatic acinar cell adenocarcinoma 10.3 SYP CHGA
33 extra-adrenal pheochromocytoma 10.3 SYP CHGA
34 papillary ependymoma 10.3 SYP MEN1
35 familial isolated pituitary adenoma 10.3 MEN1 CDKN1B
36 peritoneal serous adenocarcinoma 10.3 SYP CHGA
37 tanycytic ependymoma 10.3 SYP MEN1
38 spinal cord sarcoma 10.3 KIT CD34
39 laryngeal neuroendocrine tumor 10.3 SYP SST CHGA
40 glomangioma 10.2 SYP CD34
41 hormone producing pituitary cancer 10.2 SST MEN1
42 gallbladder leiomyoma 10.2 KIT CD34
43 binswanger's disease 10.2 SYP SST CHGA
44 adrenal medulla cancer 10.2 SYP SST CHGA
45 laryngeal small cell carcinoma 10.2 SYP KIT CHGA
46 pancreatoblastoma 10.2 SYP SST CHGA
47 mucocele of appendix 10.2 KIT CD34
48 pulmonary blastoma 10.2 SYP SST CHGA
49 gallbladder leiomyosarcoma 10.2 KIT CD34
50 benign fibrous mesothelioma 10.2 KIT CD34

Graphical network of the top 20 diseases related to Small Intestine Benign Neoplasm:



Diseases related to Small Intestine Benign Neoplasm

Symptoms & Phenotypes for Small Intestine Benign Neoplasm

MGI Mouse Phenotypes related to Small Intestine Benign Neoplasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.7 ANO1 APC CDKN1B CHGA ENO2 HOOK3
2 nervous system MP:0003631 9.32 ANO1 APC CDKN1B CHGA ENO2 IPMK

Drugs & Therapeutics for Small Intestine Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Small Intestine Benign Neoplasm

Genetic Tests for Small Intestine Benign Neoplasm

Genetic tests related to Small Intestine Benign Neoplasm:

# Genetic test Affiliating Genes
1 Neoplasm of the Small Intestine 29

Anatomical Context for Small Intestine Benign Neoplasm

MalaCards organs/tissues related to Small Intestine Benign Neoplasm:

40
Small Intestine

Publications for Small Intestine Benign Neoplasm

Articles related to Small Intestine Benign Neoplasm:

# Title Authors PMID Year
1
[Clinical analysis of primary small intestinal neoplasms in 305 cases]. 61
18396694 2007
2
[A case of primary jejunal adenocarcinoma diagnosed by enteroscopy using pediatric colonoscope]. 61
17132927 2006
3
Usefulness of MR imaging for diseases of the small intestine: comparison with CT. 61
11752928 2000
4
Imaging of primary small intestinal tumours by enteroclysis and CT with pathological correlation. 61
9166558 1997
5
A case of extragenital choriocarcinoma in the jejunum. 61
1858745 1991
6
Tumors of the small intestine. 61
3285475 1988
7
Three cases of small-intestinal neoplasm with unusual clinical features. 61
13059482 1953
8
Three cases of small intestinal neoplasm. 61
13083804 1953

Variations for Small Intestine Benign Neoplasm

Expression for Small Intestine Benign Neoplasm

Search GEO for disease gene expression data for Small Intestine Benign Neoplasm.

Pathways for Small Intestine Benign Neoplasm

Pathways related to Small Intestine Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.69 KIT CDKN1B CD34

GO Terms for Small Intestine Benign Neoplasm

Biological processes related to Small Intestine Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell cycle arrest GO:0007050 9.58 MLF1 CDKN1B APC
2 mast cell degranulation GO:0043303 9.37 KIT CHGA
3 positive regulation of pseudopodium assembly GO:0031274 9.32 KIT APC
4 myeloid progenitor cell differentiation GO:0002318 9.26 MLF1 KIT
5 mast cell chemotaxis GO:0002551 9.16 KIT CHGA
6 negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736 9.13 MEN1 CDKN1B APC
7 mast cell cytokine production GO:0032762 8.62 KIT CHGA

Sources for Small Intestine Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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