MCID: SMT017
MIFTS: 19

Somatomammotropinoma

Categories: Endocrine diseases, Rare diseases

Aliases & Classifications for Somatomammotropinoma

Summaries for Somatomammotropinoma

MalaCards based summary : Somatomammotropinoma, also known as growth hormone and prolactin cosecreting pituitary adenoma, is related to familial isolated pituitary adenoma. Affiliated tissues include pituitary and skin, and related phenotypes are osteoarthritis and hyperhidrosis

Related Diseases for Somatomammotropinoma

Diseases related to Somatomammotropinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 familial isolated pituitary adenoma 11.3

Symptoms & Phenotypes for Somatomammotropinoma

Human phenotypes related to Somatomammotropinoma:

58 31 (show top 50) (show all 62)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 osteoarthritis 58 31 hallmark (90%) Very frequent (99-80%) HP:0002758
2 hyperhidrosis 58 31 hallmark (90%) Very frequent (99-80%) HP:0000975
3 macroglossia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000158
4 coarse facial features 58 31 hallmark (90%) Very frequent (99-80%) HP:0000280
5 macrotia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000400
6 mandibular prognathia 58 31 hallmark (90%) Very frequent (99-80%) HP:0000303
7 fatigue 58 31 hallmark (90%) Very frequent (99-80%) HP:0012378
8 joint swelling 58 31 hallmark (90%) Very frequent (99-80%) HP:0001386
9 arthralgia 58 31 hallmark (90%) Very frequent (99-80%) HP:0002829
10 full cheeks 58 31 hallmark (90%) Very frequent (99-80%) HP:0000293
11 thick lower lip vermilion 58 31 hallmark (90%) Very frequent (99-80%) HP:0000179
12 anterior hypopituitarism 58 31 hallmark (90%) Very frequent (99-80%) HP:0000830
13 broad forehead 58 31 hallmark (90%) Very frequent (99-80%) HP:0000337
14 long face 58 31 hallmark (90%) Very frequent (99-80%) HP:0000276
15 growth hormone excess 58 31 hallmark (90%) Very frequent (99-80%) HP:0000845
16 wide nose 58 31 hallmark (90%) Very frequent (99-80%) HP:0000445
17 tall stature 58 31 hallmark (90%) Very frequent (99-80%) HP:0000098
18 large hands 58 31 hallmark (90%) Very frequent (99-80%) HP:0001176
19 tapered finger 58 31 hallmark (90%) Very frequent (99-80%) HP:0001182
20 macrodactyly 58 31 hallmark (90%) Very frequent (99-80%) HP:0004099
21 broad foot 58 31 hallmark (90%) Very frequent (99-80%) HP:0001769
22 deep plantar creases 58 31 hallmark (90%) Very frequent (99-80%) HP:0001869
23 cortical diaphyseal thickening of the upper limbs 58 31 hallmark (90%) Very frequent (99-80%) HP:0003859
24 deep palmar crease 58 31 hallmark (90%) Very frequent (99-80%) HP:0006191
25 increased circulating prolactin concentration 31 hallmark (90%) HP:0000870
26 frontal bossing 58 31 frequent (33%) Frequent (79-30%) HP:0002007
27 depressivity 58 31 frequent (33%) Frequent (79-30%) HP:0000716
28 kyphosis 58 31 frequent (33%) Frequent (79-30%) HP:0002808
29 sleep apnea 58 31 frequent (33%) Frequent (79-30%) HP:0010535
30 diabetes mellitus 58 31 frequent (33%) Frequent (79-30%) HP:0000819
31 hypertension 58 31 frequent (33%) Frequent (79-30%) HP:0000822
32 widely spaced teeth 58 31 frequent (33%) Frequent (79-30%) HP:0000687
33 generalized hirsutism 58 31 frequent (33%) Frequent (79-30%) HP:0002230
34 anxiety 58 31 frequent (33%) Frequent (79-30%) HP:0000739
35 hypogonadotrophic hypogonadism 58 31 frequent (33%) Frequent (79-30%) HP:0000044
36 migraine 58 31 frequent (33%) Frequent (79-30%) HP:0002076
37 paresthesia 58 31 frequent (33%) Frequent (79-30%) HP:0003401
38 palpebral edema 58 31 frequent (33%) Frequent (79-30%) HP:0100540
39 synophrys 58 31 frequent (33%) Frequent (79-30%) HP:0000664
40 pituitary prolactin cell adenoma 58 31 frequent (33%) Frequent (79-30%) HP:0006767
41 pituitary growth hormone cell adenoma 58 31 frequent (33%) Frequent (79-30%) HP:0011760
42 hoarse voice 58 31 frequent (33%) Frequent (79-30%) HP:0001609
43 spinal canal stenosis 58 31 frequent (33%) Frequent (79-30%) HP:0003416
44 cerebral palsy 58 31 frequent (33%) Frequent (79-30%) HP:0100021
45 abnormal toenail morphology 58 31 frequent (33%) Frequent (79-30%) HP:0008388
46 broad jaw 58 31 frequent (33%) Frequent (79-30%) HP:0012802
47 dysmenorrhea 58 31 frequent (33%) Frequent (79-30%) HP:0100607
48 galactorrhea 58 31 frequent (33%) Frequent (79-30%) HP:0100829
49 amenorrhea 58 31 frequent (33%) Frequent (79-30%) HP:0000141
50 abnormal fingernail morphology 31 frequent (33%) HP:0001231

Drugs & Therapeutics for Somatomammotropinoma

Search Clinical Trials , NIH Clinical Center for Somatomammotropinoma

Genetic Tests for Somatomammotropinoma

Anatomical Context for Somatomammotropinoma

MalaCards organs/tissues related to Somatomammotropinoma:

40
Pituitary, Skin

Publications for Somatomammotropinoma

Articles related to Somatomammotropinoma:

# Title Authors PMID Year
1
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells. 61
29987187 2018
2
[Multiple endocrine neoplasia type 1 syndrome with three classical components and chiasm glioma: specific features of target organ lesions and a clinical observation]. 61
27035001 2015
3
AIP-Related Familial Isolated Pituitary Adenomas 61
22720333 2012

Variations for Somatomammotropinoma

Expression for Somatomammotropinoma

Search GEO for disease gene expression data for Somatomammotropinoma.

Pathways for Somatomammotropinoma

GO Terms for Somatomammotropinoma

Sources for Somatomammotropinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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