MCID: SPR006
MIFTS: 35

Sparganosis

Categories: Ear diseases, Infectious diseases, Neuronal diseases, Respiratory diseases

Aliases & Classifications for Sparganosis

MalaCards integrated aliases for Sparganosis:

Name: Sparganosis 12 44 15 73
Infection by Sparganum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10080
ICD10 33 B70.1
ICD9CM 35 123.5
MeSH 44 D013031
NCIt 50 C35030
SNOMED-CT 68 31659000
UMLS 73 C0037753

Summaries for Sparganosis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection by the genus Spirometra. A painful nodule develops after the plerocercoid larvae migrate to the brain causing cerebral sparganosis. Subcutaneous tissue, breast, orbit, urinary tract, pleural cavity, lungs, abdominal viscera and inner ear can be infected.

MalaCards based summary : Sparganosis, also known as infection by sparganum, is related to diphyllobothriasis and lymphoma. An important gene associated with Sparganosis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Cardiac muscle contraction. Affiliated tissues include brain, lung and spinal cord.

Wikipedia : 76 Sparganosis is a parasitic infection caused by the Diphyllobothrium or the plerocercoid larvae of the... more...

Related Diseases for Sparganosis

Diseases related to Sparganosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 diphyllobothriasis 30.3 MT-CO1 MT-ND3
2 lymphoma 10.1
3 deafness, aminoglycoside-induced 10.0 MT-CO1 MT-ND4
4 pediculus humanus capitis infestation 10.0 MT-CO1 MT-CYB
5 amelogenesis imperfecta, type iv 10.0 MT-CO1 MT-CYB
6 cercarial dermatitis 10.0 MT-CO1 MT-ND4
7 myasthenic syndrome, congenital, 10 10.0 MT-CO1 MT-CYB
8 cysticercosis 10.0
9 hemopericardium 10.0
10 pericardial effusion 10.0
11 taeniasis 10.0 CTSL MT-CO1
12 deafness, nonsyndromic sensorineural, mitochondrial 10.0 MT-CO1 MT-ND4
13 acute retrobulbar neuritis 10.0 MT-CYB MT-ND4
14 gnathomiasis 10.0 CTSL MT-CO1
15 carrion's disease 10.0 MT-CYB MT-ND4
16 parasitic protozoa infectious disease 10.0 MT-CO1 MT-CYB
17 parasitic helminthiasis infectious disease 9.9 CTSL MT-CO1
18 mitochondrial complex iv deficiency 9.9 MT-CO1 MT-ND4
19 leber optic atrophy and dystonia 9.9 MT-ND3 MT-ND4
20 striatonigral degeneration, infantile, mitochondrial 9.9 MT-ND3 MT-ND4
21 striatonigral degeneration, infantile 9.9 MT-ND3 MT-ND4
22 myopathy, lactic acidosis, and sideroblastic anemia 3 9.9 MT-ND3 MT-ND4
23 myopathy, lactic acidosis, and sideroblastic anemia 9.9 MT-ND3 MT-ND4
24 ataxia and polyneuropathy, adult-onset 9.9 MT-ND3 MT-ND4
25 mitochondrial myopathy 9.9 MT-CO1 MT-CYB MT-ND4
26 lactic acidosis 9.9 MT-CO1 MT-CYB MT-ND4
27 breast cancer 9.9
28 myositis 9.9
29 b-cell lymphomas 9.9
30 diffuse large b-cell lymphoma 9.9
31 follicular lymphoma 9.9
32 hydrocephalus 9.9
33 coenurosis 9.9
34 sarcoma 9.9
35 cauda equina syndrome 9.9
36 echinococcosis 9.9
37 pneumothorax 9.9
38 cystitis 9.9
39 status epilepticus 9.9
40 epilepsy 9.9
41 teratoma 9.9
42 posterior cerebral artery infarction 9.9
43 folliculitis 9.9
44 peritonitis 9.9
45 intestinal obstruction 9.9
46 vasculitis 9.9
47 myeloid sarcoma 9.9
48 hydrocele 9.9
49 toxoplasmosis 9.9
50 eosinophilic cystitis 9.9

Graphical network of the top 20 diseases related to Sparganosis:



Diseases related to Sparganosis

Symptoms & Phenotypes for Sparganosis

Drugs & Therapeutics for Sparganosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study for the Ocular Toxocariasis Patients With the Pulmonary Toxocariasis, and Ocular Toxocariasis Cohort Recruiting NCT03814837

Search NIH Clinical Center for Sparganosis

Cochrane evidence based reviews: sparganosis

Genetic Tests for Sparganosis

Anatomical Context for Sparganosis

MalaCards organs/tissues related to Sparganosis:

41
Brain, Lung, Spinal Cord, Eye, B Cells, Myeloid, Breast

Publications for Sparganosis

Articles related to Sparganosis:

(show top 50) (show all 293)
# Title Authors Year
1
An unusual case of urinary sparganosis in the Indian subcontinent. ( 29692513 )
2018
2
Orbital sparganosis in an 8-year boy: a case report. ( 29357839 )
2018
3
Surgical Extraction of Cerebral Sparganosis: 2-Dimensional Operative Video. ( 29462374 )
2018
4
Differential Diagnosis of Human Sparganosis Using Multiplex PCR. ( 29996635 )
2018
5
Breast sparganosis: a case report. ( 30166792 )
2018
6
Dual Cestode Infection in a Thai Patient (Spinal Sparganosis and Racemose Neurocysticercosis): A Case Report. ( 30213923 )
2018
7
The first case of genetically confirmed sparganosis (Spirometra erinaceieuropaei) in European reptiles. ( 30220047 )
2018
8
Identification of sparganosis based on next-generation sequencing. ( 30315893 )
2018
9
Efficacy comparison between long-term high-dose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study. ( 30346956 )
2018
10
Human Sparganosis in Korea. ( 30369856 )
2018
11
Forehead Sparganosis. ( 28930928 )
2017
12
Molecular Identification of Spirometra erinaceieuropaei Tapeworm in Cases of Human Sparganosis, Hong Kong. ( 28322697 )
2017
13
Clinical Manifestation of a Patient With Forehead Sparganosis. ( 28328597 )
2017
14
The Brief Case: Central Nervous System Sparganosis in a 53-Year-Old Thai Man. ( 28122993 )
2017
15
A neglected risk for sparganosis: eating live tadpoles in central China. ( 28468685 )
2017
16
Ultrasound-Assisted Neuronavigation-Guided Removal of a Live Worm in Cerebral Sparganosis. ( 28315796 )
2017
17
Closing the Brief Case: Central Nervous System Sparganosis in a 53-Year-Old Thai Man. ( 28122996 )
2017
18
Molecular identification of intramuscular and subcutaneous Spirometra erinaceiuropaei sparganosis in a Japanese patient. ( 28106263 )
2017
19
Sparganosis of the Unilateral Breast: A Case Report. ( 28877574 )
2017
20
Seropositivity and identification of paramyosin for sparganosis in the Kangwon and Incheon provinces of the Republic of Korea. ( 27628641 )
2016
21
Seroprevalence of Sparganosis in Rural Communities of Northern Tanzania. ( 27481059 )
2016
22
Cerebral Sparganosis in Children: Epidemiologic and Radiologic Characteristics and Treatment Outcomes: A Report of 9 Cases. ( 26855309 )
2016
23
Sparganosis in wild boar (Sus scrofa) - Implications for veterinarians, hunters, and consumers. ( 27523946 )
2016
24
A case of disseminated central nervous system sparganosis. ( 28031991 )
2016
25
Thoracoscopic examination of empyema in a patient with sparganosis mansoni. ( 26603428 )
2016
26
Endoscopic resection of sparganosis presenting as colon submucosal tumor: A case report. ( 27217709 )
2016
27
Presumptive case of sparganosis manifesting as a hepatic mass: A case report and literature review. ( 27843543 )
2016
28
Imaging characteristics of cerebral sparganosis with live worms. ( 27726888 )
2016
29
Serodiagnosis of sparganosis by ELISA using recombinant cysteine protease of Spirometra erinaceieuropaei spargana. ( 25532486 )
2015
30
Cerebral sparganosis: case report and review of the European cases. ( 26085111 )
2015
31
Sparganosis presenting as pericardial effusion and lung lesions. ( 25948364 )
2015
32
Thirty-Seven Human Cases of Sparganosis from Ethiopia and South Sudan Caused by Spirometra Spp. ( 26055739 )
2015
33
Clinical Features and Outcomes of Patients With Pulmonary Sparganosis. ( 26465081 )
2015
34
Occurrence of human sparganosis in Kerala. ( 26688651 )
2015
35
Characterization of Spirometra erinaceieuropaei Plerocercoid Cysteine Protease and Potential Application for Serodiagnosis of Sparganosis. ( 26046773 )
2015
36
INTRAOSSEOUS PROLIFERATIVE SPARGANOSIS PRESENTING AS A PATHOLOGICAL FRACTURE: A CASE REPORT AND REVIEW OF THE LITERATURE. ( 26867374 )
2015
37
Human sparganosis, a neglected food borne zoonosis. ( 26364132 )
2015
38
Cutaneous sparganosis: a rare parasitic infection. ( 25799891 )
2015
39
Cutaneous sparganosis: a rare parasitic infection. ( 25626616 )
2015
40
Breast sparganosis and incidentally detected subcutaneous and intramuscular sparganosis at several sites: case report and literature review. ( 25725936 )
2015
41
Ocular sparganosis from Assam. ( 25709957 )
2015
42
Nine human sparganosis cases in Thailand with molecular identification of causative parasite species. ( 24842879 )
2014
43
Recurred sparganosis 1 year after surgical removal of a sparganum in a Korean woman. ( 24623886 )
2014
44
The first report of sparganosis (Spirometra sp.) in Eurasian badger (Meles meles). ( 24398022 )
2014
45
Diagnostic efficacy of a recombinant cysteine protease of Spirometra erinacei larvae for serodiagnosis of sparganosis. ( 24623880 )
2014
46
Sparganosis in patient with lymphoma. ( 25313786 )
2014
47
Acanthocephalan infection and sparganosis in a green tree snake (Dendrelaphis punctulata). ( 25156057 )
2014
48
Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012. ( 25372227 )
2014
49
Sparganosis in Russell's viper snake: a case report. ( 25320490 )
2014
50
Pulmonary sparganosis mansoni: a case report from a non-endemic region. ( 24977019 )
2014

Variations for Sparganosis

Expression for Sparganosis

Search GEO for disease gene expression data for Sparganosis.

Pathways for Sparganosis

GO Terms for Sparganosis

Cellular components related to Sparganosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.62 MT-CO1 MT-CYB MT-ND3 MT-ND4
2 mitochondrial membrane GO:0031966 9.37 MT-ND3 MT-ND4
3 mitochondrial respiratory chain complex I GO:0005747 9.26 MT-ND3 MT-ND4
4 mitochondrial inner membrane GO:0005743 9.26 MT-CO1 MT-CYB MT-ND3 MT-ND4
5 mitochondrial respiratory chain complex III GO:0005750 9.16 MT-CO1 MT-CYB
6 respiratory chain GO:0070469 8.92 MT-CO1 MT-CYB MT-ND3 MT-ND4

Biological processes related to Sparganosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.51 MT-CO1 MT-ND4
2 response to hypoxia GO:0001666 9.49 MT-CYB MT-ND4
3 response to oxidative stress GO:0006979 9.48 MT-CO1 MT-ND3
4 response to ethanol GO:0045471 9.46 MT-CYB MT-ND4
5 mitochondrial respiratory chain complex I assembly GO:0032981 9.43 MT-ND3 MT-ND4
6 response to hormone GO:0009725 9.4 MT-CYB MT-ND3
7 cerebellum development GO:0021549 9.37 MT-CO1 MT-ND4
8 mitochondrial electron transport, NADH to ubiquinone GO:0006120 9.32 MT-ND3 MT-ND4
9 aerobic respiration GO:0009060 9.26 MT-CO1 MT-ND4
10 oxidation-reduction process GO:0055114 9.26 MT-CO1 MT-CYB MT-ND3 MT-ND4
11 response to copper ion GO:0046688 9.16 MT-CO1 MT-CYB
12 electron transport coupled proton transport GO:0015990 8.8 MT-CO1 MT-CYB MT-ND4

Molecular functions related to Sparganosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.96 MT-ND3 MT-ND4
2 oxidoreductase activity GO:0016491 8.92 MT-CO1 MT-CYB MT-ND3 MT-ND4

Sources for Sparganosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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