MCID: SPR006
MIFTS: 35

Sparganosis

Categories: Ear diseases, Infectious diseases, Neuronal diseases, Respiratory diseases

Aliases & Classifications for Sparganosis

MalaCards integrated aliases for Sparganosis:

Name: Sparganosis 12 45 15 17 74
Infection by Sparganum 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10080
ICD9CM 36 123.5
MeSH 45 D013031
NCIt 51 C35030
SNOMED-CT 69 31659000
ICD10 34 B70.1
UMLS 74 C0037753

Summaries for Sparganosis

Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves parasitic infection by the genus Spirometra. A painful nodule develops after the plerocercoid larvae migrate to the brain causing cerebral sparganosis. Subcutaneous tissue, breast, orbit, urinary tract, pleural cavity, lungs, abdominal viscera and inner ear can be infected.

MalaCards based summary : Sparganosis, also known as infection by sparganum, is related to diphyllobothriasis and lymphoma. An important gene associated with Sparganosis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Cardiac muscle contraction. Affiliated tissues include brain, spinal cord and skin.

Wikipedia : 77 Sparganosis is a parasitic infection caused by the plerocercoid larvae of the genus Spirometra including... more...

Related Diseases for Sparganosis

Diseases related to Sparganosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 diphyllobothriasis 30.2 MT-CO1 MT-ND3
2 lymphoma 10.1
3 deafness, aminoglycoside-induced 10.1 MT-CO1 MT-ND4
4 pediculus humanus capitis infestation 10.1 MT-CO1 MT-CYB
5 amelogenesis imperfecta, type iv 10.1 MT-CO1 MT-CYB
6 cysticercosis 10.0
7 hemopericardium 10.0
8 pericardial effusion 10.0
9 cercarial dermatitis 10.0 MT-CO1 MT-ND4
10 myasthenic syndrome, congenital, 10 10.0 MT-CO1 MT-CYB
11 taeniasis 10.0 CTSL MT-CO1
12 deafness, nonsyndromic sensorineural, mitochondrial 10.0 MT-CO1 MT-ND4
13 acute retrobulbar neuritis 10.0 MT-CYB MT-ND4
14 gnathomiasis 10.0 CTSL MT-CO1
15 carrion's disease 9.9 MT-CYB MT-ND4
16 parasitic protozoa infectious disease 9.9 MT-CO1 MT-CYB
17 breast cancer 9.9
18 myositis 9.9
19 hemorrhage, intracerebral 9.9
20 melioidosis 9.9
21 diffuse large b-cell lymphoma 9.9
22 follicular lymphoma 9.9
23 hydrocephalus 9.9
24 coenurosis 9.9
25 sarcoma 9.9
26 cauda equina syndrome 9.9
27 echinococcosis 9.9
28 pneumothorax 9.9
29 cystitis 9.9
30 status epilepticus 9.9
31 epilepsy 9.9
32 teratoma 9.9
33 pleural empyema 9.9
34 posterior cerebral artery infarction 9.9
35 folliculitis 9.9
36 peritonitis 9.9
37 intestinal obstruction 9.9
38 vasculitis 9.9
39 myeloid sarcoma 9.9
40 orbital plasma cell granuloma 9.9
41 hydrocele 9.9
42 toxoplasmosis 9.9
43 eosinophilic cystitis 9.9
44 fournier gangrene 9.9
45 mediastinal endodermal sinus tumors 9.9
46 parasitic helminthiasis infectious disease 9.9 CTSL MT-CO1
47 mitochondrial complex iv deficiency 9.9 MT-CO1 MT-ND4
48 leber optic atrophy and dystonia 9.9 MT-ND3 MT-ND4
49 striatonigral degeneration, infantile, mitochondrial 9.9 MT-ND3 MT-ND4
50 striatonigral degeneration, infantile 9.9 MT-ND3 MT-ND4

Graphical network of the top 20 diseases related to Sparganosis:



Diseases related to Sparganosis

Symptoms & Phenotypes for Sparganosis

Drugs & Therapeutics for Sparganosis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study for the Ocular Toxocariasis Patients With the Pulmonary Toxocariasis, and Ocular Toxocariasis Cohort Recruiting NCT03814837

Search NIH Clinical Center for Sparganosis

Cochrane evidence based reviews: sparganosis

Genetic Tests for Sparganosis

Anatomical Context for Sparganosis

MalaCards organs/tissues related to Sparganosis:

42
Brain, Spinal Cord, Skin, Colon, Lymph Node, Eye, Myeloid

Publications for Sparganosis

Articles related to Sparganosis:

(show top 50) (show all 305)
# Title Authors Year
1
Breast Sparganosis Presenting with a Painless Breast Lump: Report of Two Cases. ( 31104411 )
2019
2
A case of mammary sparganosis due to infection with Spirometra mansoni. ( 31079421 )
2019
3
Sparganosis: an under-recognised zoonosis in Australia? ( 31061178 )
2019
4
Diagnosis and treatment of human sparganosis. ( 31034386 )
2019
5
Diagnosis and surgical management of orbital sparganosis. ( 30944463 )
2019
6
Development of EST-derived microsatellite markers to investigate the population structure of sparganum - the causative agent of zoonotic sparganosis. ( 30859932 )
2019
7
Subcutaneous sparganosis mimicking soft tissue tumor: a case report. ( 30858734 )
2019
8
First report of sparganosis manifested by pleuritis and decreased peripheral blood eosinophils in Jiangsu province, China. ( 30847612 )
2019
9
The first case of human sparganosis in Poland and a review of the cases in Europe. ( 30794872 )
2019
10
Follow-up study of high-dose praziquantel therapy for cerebral sparganosis. ( 30640909 )
2019
11
Orbital sparganosis in an 8-year boy: a case report. ( 29357839 )
2018
12
Surgical Extraction of Cerebral Sparganosis: 2-Dimensional Operative Video. ( 29462374 )
2018
13
An unusual case of urinary sparganosis in the Indian subcontinent. ( 29692513 )
2018
14
Differential Diagnosis of Human Sparganosis Using Multiplex PCR. ( 29996635 )
2018
15
Breast sparganosis: a case report. ( 30166792 )
2018
16
Dual Cestode Infection in a Thai Patient (Spinal Sparganosis and Racemose Neurocysticercosis): A Case Report. ( 30213923 )
2018
17
The first case of genetically confirmed sparganosis (Spirometra erinaceieuropaei) in European reptiles. ( 30220047 )
2018
18
Identification of sparganosis based on next-generation sequencing. ( 30315893 )
2018
19
Efficacy comparison between long-term high-dose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study. ( 30346956 )
2018
20
Subcutaneous Sparganosis of the Breast. ( 30666275 )
2018
21
Human Sparganosis in Korea. ( 30369856 )
2018
22
The Tunnel Sign Revisited: A Novel Observation of Cerebral Melioidosis Mimicking Sparganosis. ( 30651915 )
2018
23
Forehead Sparganosis. ( 28930928 )
2017
24
Sparganosis of the Unilateral Breast: A Case Report. ( 28877574 )
2017
25
A neglected risk for sparganosis: eating live tadpoles in central China. ( 28468685 )
2017
26
Clinical Manifestation of a Patient With Forehead Sparganosis. ( 28328597 )
2017
27
Molecular Identification of Spirometra erinaceieuropaei Tapeworm in Cases of Human Sparganosis, Hong Kong. ( 28322697 )
2017
28
Ultrasound-Assisted Neuronavigation-Guided Removal of a Live Worm in Cerebral Sparganosis. ( 28315796 )
2017
29
Closing the Brief Case: Central Nervous System Sparganosis in a 53-Year-Old Thai Man. ( 28122996 )
2017
30
The Brief Case: Central Nervous System Sparganosis in a 53-Year-Old Thai Man. ( 28122993 )
2017
31
Molecular identification of intramuscular and subcutaneous Spirometra erinaceiuropaei sparganosis in a Japanese patient. ( 28106263 )
2017
32
Seropositivity and identification of paramyosin for sparganosis in the Kangwon and Incheon provinces of the Republic of Korea. ( 27628641 )
2017
33
A case of disseminated central nervous system sparganosis. ( 28031991 )
2016
34
Presumptive case of sparganosis manifesting as a hepatic mass: A case report and literature review. ( 27843543 )
2016
35
Imaging characteristics of cerebral sparganosis with live worms. ( 27726888 )
2016
36
Sparganosis in wild boar (Sus scrofa) - Implications for veterinarians, hunters, and consumers. ( 27523946 )
2016
37
Seroprevalence of Sparganosis in Rural Communities of Northern Tanzania. ( 27481059 )
2016
38
Endoscopic resection of sparganosis presenting as colon submucosal tumor: A case report. ( 27217709 )
2016
39
Cerebral Sparganosis in Children: Epidemiologic and Radiologic Characteristics and Treatment Outcomes: A Report of 9 Cases. ( 26855309 )
2016
40
Thoracoscopic examination of empyema in a patient with sparganosis mansoni. ( 26603428 )
2016
41
INTRAOSSEOUS PROLIFERATIVE SPARGANOSIS PRESENTING AS A PATHOLOGICAL FRACTURE: A CASE REPORT AND REVIEW OF THE LITERATURE. ( 26867374 )
2015
42
Occurrence of human sparganosis in Kerala. ( 26688651 )
2015
43
Clinical Features of Pulmonary Sparganosis. ( 26465081 )
2015
44
Human sparganosis, a neglected food borne zoonosis. ( 26364132 )
2015
45
Cerebral sparganosis: case report and review of the European cases. ( 26085111 )
2015
46
Thirty-Seven Human Cases of Sparganosis from Ethiopia and South Sudan Caused by Spirometra Spp. ( 26055739 )
2015
47
Characterization of Spirometra erinaceieuropaei Plerocercoid Cysteine Protease and Potential Application for Serodiagnosis of Sparganosis. ( 26046773 )
2015
48
Cutaneous sparganosis: a rare parasitic infection. ( 25799891 )
2015
49
Breast sparganosis and incidentally detected subcutaneous and intramuscular sparganosis at several sites: case report and literature review. ( 25725936 )
2015
50
Ocular sparganosis from Assam. ( 25709957 )
2015

Variations for Sparganosis

Expression for Sparganosis

Search GEO for disease gene expression data for Sparganosis.

Pathways for Sparganosis

GO Terms for Sparganosis

Cellular components related to Sparganosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.62 MT-CO1 MT-CYB MT-ND3 MT-ND4
2 mitochondrial membrane GO:0031966 9.37 MT-ND3 MT-ND4
3 mitochondrial respiratory chain complex I GO:0005747 9.26 MT-ND3 MT-ND4
4 mitochondrial inner membrane GO:0005743 9.26 MT-CO1 MT-CYB MT-ND3 MT-ND4
5 mitochondrial respiratory chain complex III GO:0005750 9.16 MT-CO1 MT-CYB
6 respiratory chain GO:0070469 8.92 MT-CO1 MT-CYB MT-ND3 MT-ND4

Biological processes related to Sparganosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 aging GO:0007568 9.51 MT-CO1 MT-ND4
2 response to hypoxia GO:0001666 9.49 MT-CYB MT-ND4
3 response to oxidative stress GO:0006979 9.48 MT-CO1 MT-ND3
4 response to ethanol GO:0045471 9.46 MT-CYB MT-ND4
5 mitochondrial respiratory chain complex I assembly GO:0032981 9.43 MT-ND3 MT-ND4
6 response to hormone GO:0009725 9.4 MT-CYB MT-ND3
7 cerebellum development GO:0021549 9.37 MT-CO1 MT-ND4
8 mitochondrial electron transport, NADH to ubiquinone GO:0006120 9.32 MT-ND3 MT-ND4
9 aerobic respiration GO:0009060 9.26 MT-CO1 MT-ND4
10 oxidation-reduction process GO:0055114 9.26 MT-CO1 MT-CYB MT-ND3 MT-ND4
11 response to copper ion GO:0046688 9.16 MT-CO1 MT-CYB
12 electron transport coupled proton transport GO:0015990 8.8 MT-CO1 MT-CYB MT-ND4

Molecular functions related to Sparganosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADH dehydrogenase (ubiquinone) activity GO:0008137 8.96 MT-ND3 MT-ND4
2 oxidoreductase activity GO:0016491 8.62 MT-CO1 MT-CYB

Sources for Sparganosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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