FA1
MCID: SPR122
MIFTS: 16

Sperm-Specific Antigen 1 (FA1)

Categories: Reproductive diseases

Aliases & Classifications for Sperm-Specific Antigen 1

MalaCards integrated aliases for Sperm-Specific Antigen 1:

Name: Sperm-Specific Antigen 1 58
Fertilization Antigen 1; Fa1 58
Fertilization Antigen 1 58
Ssfa1 58
Fa1 58

Classifications:



External Ids:

OMIM 58 601876

Summaries for Sperm-Specific Antigen 1

MalaCards based summary : Sperm-Specific Antigen 1, is also known as fertilization antigen 1; fa1. An important gene associated with Sperm-Specific Antigen 1 is SNU13 (Small Nuclear Ribonucleoprotein 13). The drugs Ergocalciferol and Vitamin D have been mentioned in the context of this disorder. Affiliated tissues include bone, retina and testis.

Description from OMIM: 601876

Related Diseases for Sperm-Specific Antigen 1

Symptoms & Phenotypes for Sperm-Specific Antigen 1

Clinical features from OMIM:

601876

Drugs & Therapeutics for Sperm-Specific Antigen 1

Drugs for Sperm-Specific Antigen 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ergocalciferol Approved, Nutraceutical Phase 3 50-14-6 5280793
2
Vitamin D Approved, Nutraceutical, Vet_approved Phase 3 1406-16-2
3
Vitamin D3 Approved, Nutraceutical Phase 3 67-97-0 5280795 6221
4
Calcium Approved, Nutraceutical Phase 3 7440-70-2 271
5 Calciferol Phase 3
6 Bone Density Conservation Agents Phase 3
7 Ergocalciferols Phase 3
8 Vitamin D2 Phase 3
9 Hormones Phase 3
10 Nutrients Phase 3
11 Trace Elements Phase 3
12 Vitamins Phase 3
13 Insulin, Globin Zinc Phase 3
14 Micronutrients Phase 3
15 insulin Phase 3
16 Calcium, Dietary Phase 3
17
Heparin Approved, Investigational Phase 1 9005-49-6 772 46507594
18 calcium heparin Phase 1
19 beta-Hydroxy-beta-methylbutyrate Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hypovitaminosis D : A Link Between Bone/Mineral and Fat/Fuel Metabolism Completed NCT01315366 Phase 3
2 Pilot/Ph I Safety and Efficacy of ODSH in Protein Losing Enteropathy Secondary to Single Ventricle Palliative Surgery Terminated NCT01161641 Phase 1 ODSH at 0.125 mg/kg/h;ODSH at 0.375 mg/kg/h;ODSH at 0.250 mg/kg/h
3 Safety and Performance Study of Large Hole Vascular Closure Device Completed NCT02788448 Not Applicable
4 Safety and Performance Study of Large Hole Vascular Closure Device FIV Recruiting NCT03423602 Not Applicable
5 Safety and Performance Study of Large Hole Vascular Closure Device Completed NCT01943344 Not Applicable
6 Use of Diagnostic Dye to Identify Areas of Leakeage,in the Retina, Prior to Receiving Focal Laser Treatment Completed NCT01792141
7 Involvement of Nervous System in Muscle Weakness in COPD Patients Completed NCT01679782
8 The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training Completed NCT01941368 Not Applicable

Search NIH Clinical Center for Sperm-Specific Antigen 1

Genetic Tests for Sperm-Specific Antigen 1

Anatomical Context for Sperm-Specific Antigen 1

MalaCards organs/tissues related to Sperm-Specific Antigen 1:

42
Bone, Retina, Testis

Publications for Sperm-Specific Antigen 1

Articles related to Sperm-Specific Antigen 1:

# Title Authors Year
1
[The relationship between mouse fertilization antigen 1 gene and the human counterpart gene]. ( 16135423 )
2002
2
Fertilization antigen-1: cDNA cloning, testis-specific expression, and immunocontraceptive effects. ( 9114055 )
1997
3
Immunoglobulin (Ig) G, IgA, and IgA subclass antibodies against fertilization antigen-1 in cervical secretions and sera of women of infertile couples. ( 8405520 )
1993
4
The fertilization antigen-1 does not have proteolytic/acrosin activity, but its monoclonal antibody inhibits sperm capacitation and acrosome reaction. ( 1633909 )
1992

Variations for Sperm-Specific Antigen 1

Expression for Sperm-Specific Antigen 1

Search GEO for disease gene expression data for Sperm-Specific Antigen 1.

Pathways for Sperm-Specific Antigen 1

GO Terms for Sperm-Specific Antigen 1

Sources for Sperm-Specific Antigen 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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