MCID: SPR017
MIFTS: 33

Spermatocele

Categories: Reproductive diseases

Aliases & Classifications for Spermatocele

MalaCards integrated aliases for Spermatocele:

Name: Spermatocele 12 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11997
ICD9CM 35 608.1
MeSH 44 D013088
SNOMED-CT 68 43077002 49263001
UMLS 73 C0037859

Summaries for Spermatocele

MalaCards based summary : Spermatocele is related to hydrocele and male reproductive organ benign neoplasm. An important gene associated with Spermatocele is SLC26A3 (Solute Carrier Family 26 Member 3), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include testis, kidney and lung, and related phenotype is endocrine/exocrine gland.

Wikipedia : 76 Spermatocele (/sp�?ːr�?mæt�?siːl/) is a retention cyst of a tubule of the rete testis or the head of the... more...

Related Diseases for Spermatocele

Diseases related to Spermatocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 hydrocele 10.9
2 male reproductive organ benign neoplasm 10.2 NR5A1 SYP
3 panophthalmitis 10.2 SYP TERT
4 esophageal neuroendocrine tumor 10.2 NCAM1 SYP
5 ovarian large-cell neuroendocrine carcinoma 10.2 NCAM1 SYP
6 gallbladder small cell carcinoma 10.2 NCAM1 SYP
7 cutaneous ganglioneuroma 10.2 NCAM1 SYP
8 orbital cancer 10.2 NCAM1 SYP
9 hypoganglionosis 10.2 NCAM1 SYP
10 endometrial small cell carcinoma 10.2 NCAM1 SYP
11 pancreatic endocrine carcinoma 10.2 NCAM1 SYP
12 conventional angiosarcoma 10.2 NCAM1 SYP
13 supratentorial primitive neuroectodermal tumor 10.2 NCAM1 SYP
14 mediastinal cancer 10.2 NCAM1 SYP
15 kidney benign neoplasm 10.2 MME PAX2
16 angiomyoma 10.2 NCAM1 SYP
17 gastric small cell carcinoma 10.2 NCAM1 SYP
18 subependymoma 10.2 NCAM1 SYP
19 denys-drash syndrome 10.2 NR5A1 PAX2
20 water-clear cell adenoma 10.2 SYP TG
21 atypical follicular adenoma 10.2 SYP TG
22 gastric squamous cell carcinoma 10.2 NCAM1 SYP
23 orbital plasma cell granuloma 10.2 MME NCAM1
24 chronic orbital inflammation 10.2 MME NCAM1
25 male infertility 10.2
26 azoospermia 10.2
27 infertility 10.2
28 fallopian tube carcinosarcoma 10.1 CALB2 NCAM1
29 ovarian serous adenofibroma 10.1 CALB2 NCAM1
30 ovarian serous cystadenofibroma 10.1 CALB2 NCAM1
31 adenofibroma 10.1 CALB2 MME
32 venous hemangioma 10.1 CALB2 SYP
33 endometrial mucinous adenocarcinoma 10.1 PAX2 PGR
34 fallopian tube endometrioid adenocarcinoma 10.1 CALB2 MME
35 cervix small cell carcinoma 10.1 NCAM1 SYP
36 mucinous ovarian cystadenoma 10.1 CALB2 SYP
37 fallopian tube adenocarcinoma 10.1 CALB2 MME
38 soft tissue sarcoma 10.1 TERT TNF
39 malignant leydig cell tumor 10.1 CALB2 MME
40 peroneal neuropathy 10.1 MME TNF
41 papillary thymic adenocarcinoma 10.1 CALB2 TG
42 adrenal rest tumor 10.1 NCAM1 NR5A1 SYP
43 olfactory groove meningioma 10.1 PGR SYP
44 cranial nerve malignant neoplasm 10.1 NCAM1 SYP
45 rete testis adenocarcinoma 10.1 CALB2 MME
46 lung meningioma 10.1 NCAM1 PGR
47 periodontosis 10.1 KLK4 TNF
48 sella turcica neoplasm 10.1 PGR SYP
49 tuberculum sellae meningioma 10.1 PGR SYP
50 functional colonic disease 10.1 CALB2 SYP

Comorbidity relations with Spermatocele via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Spermatocele:



Diseases related to Spermatocele

Symptoms & Phenotypes for Spermatocele

MGI Mouse Phenotypes related to Spermatocele:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.17 NR5A1 PAX2 PGR SLC26A3 TERT TG

Drugs & Therapeutics for Spermatocele

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of DA-9401 on Improvement of Sperm Motility Completed NCT03258437 Not Applicable

Search NIH Clinical Center for Spermatocele

Cochrane evidence based reviews: spermatocele

Genetic Tests for Spermatocele

Anatomical Context for Spermatocele

MalaCards organs/tissues related to Spermatocele:

41
Testis, Kidney, Lung, Colon, Ovary, Spinal Cord, Cervix

Publications for Spermatocele

Articles related to Spermatocele:

(show top 50) (show all 69)
# Title Authors Year
1
131I Whole-Body Scan Incidental Uptake Due to Spermatocele. ( 28902733 )
2017
2
Spermatocele in a South African Boerboel dog. ( 26041595 )
2015
3
Tubular Ectasia of Rete Testis with Spermatocele. ( 26816970 )
2015
4
Routine Pathology Evaluation of Hydrocele and Spermatocele Specimens is Associated with Significant Costs and No Identifiable Benefit. ( 24768992 )
2014
5
Presence of benign germ cells in a fine needle aspirate of a spermatocele. ( 22045691 )
2013
6
Spermatocele following kidney transplant. ( 22487000 )
2012
7
Extra scrotal spermatocele causing lower abdominal pain: a first case report. ( 20674226 )
2011
8
A randomized trial comparing 2 doses of polidocanol sclerotherapy for hydrocele or spermatocele. ( 21849198 )
2011
9
Adult hydrocele and spermatocele. ( 21592287 )
2011
10
Small blue cells mimicking small cell carcinoma in spermatocele and hydrocele specimens: a report of 5 cases. ( 19740515 )
2010
11
Spermiophages in a giant spermatocele. ( 19941373 )
2010
12
Spermatocele presenting as acute scrotum. ( 18825632 )
2008
13
Male fertility after spermatocele formation from tunica vaginalis in patients with bilateral vas agenesis. ( 18580017 )
2008
14
Bilateral spermatocele concurrent with bilateral scrotal hydrocele presenting huge scrotal swelling. ( 18018592 )
2007
15
Giant spermatocele mimicking hydrocele: a case report. ( 17606432 )
2007
16
Theriogenology question of the month. Seminoma, spermatocele, sustentacular cell tumor. ( 15906562 )
2005
17
What causes a spermatocele, and how is it usually removed? ( 15132122 )
2004
18
Spermatocele: a rare complication of rectal surgery and radiotherapy. Case report. ( 15154581 )
2004
19
Retrieval and cryopreservation of sperm from spermatocele fluid. ( 12597959 )
2003
20
Primary bilateral spermatocele. ( 12534930 )
2003
21
Torsion of spermatocele: a rare manifestation. ( 12187053 )
2002
22
Multilocular spermatocele: a case report. ( 11583363 )
2001
23
Spermatocele in a common noctule (Nyctalus noctula). ( 10638800 )
1999
24
Synergistic action of steroids and spermatocele fluid on in vitro proliferation of prostate stroma. ( 9598570 )
1998
25
Intratesticular spermatocele. ( 9610575 )
1998
26
Torsion of spermatocele and aplasia of the vas deferens. A case report. ( 9165262 )
1997
27
Percutaneous sperm aspiration of a spermatocele for intracytoplasmic sperm injection. ( 9302159 )
1997
28
Torsion of a spermatocele. ( 7500478 )
1995
29
Development of a new alloplastic spermatocele demonstrating successful sperm retrieval in an animal model. ( 7789555 )
1995
30
Alloplastic spermatocele: 20 years experience and perspectives. ( 7618373 )
1994
31
Congenital absence of vas deferens treated by artificial spermatocele constructed from the tunica vaginalis; report of six cases. ( 8272538 )
1993
32
Effect of spermatocele fluid on growth of human prostatic cells in culture. ( 8226302 )
1993
33
Clinical experience and successful impregnation using an artificial spermatocele. ( 1771703 )
1991
34
Artificial spermatocele persisting for 14 years. ( 2398578 )
1990
35
Torsion of a spermatocele: a case report and review of the literature. ( 2313807 )
1990
36
In vitro fertilization with spermatozoa from alloplastic spermatocele. ( 2318332 )
1990
37
Implantation of artificial spermatocele with cup-shaped prosthesis for excretory azoospermia and chemical management of aspirated spermatozoa. ( 3745009 )
1986
38
Alloplastic spermatocele: poor sperm motility in intraoperative epididymal fluid contraindicates prosthesis implantation. ( 3735504 )
1986
39
"Spermatocele" following abdominoperineal resection and radiotherapy. ( 3698760 )
1986
40
Fertilization of human oocytes by spermatozoa from an artificial spermatocele. ( 3788432 )
1986
41
Alloplastic spermatocele. ( 3735514 )
1986
42
Properties of human epididymal sperm obtained from an alloplastic spermatocele: motility assessment and penetration of zona-free hamster oocytes in the presence and absence of caffeine. ( 4029429 )
1985
43
Torsion of spermatocele: a newly described entity with 2 case reports. ( 3981724 )
1985
44
Alloplastic spermatocele in cases of vasa aplasia. ( 4051632 )
1985
45
A new type of alloplastic spermatocele: the bridge spermatocele. ( 6708803 )
1984
46
Alloplastic spermatocele: diffusion across the allograft material and survival of spermatozoa in vitro and in vivo. ( 6471203 )
1984
47
Clinical experience with an artificial spermatocele. ( 6469865 )
1984
48
Artificial spermatocele inserted onto the vas deferens: a clinical report. ( 6367333 )
1983
49
Outpatient hydrocele and spermatocele repair under local anesthesia. ( 6348308 )
1983
50
Experimental studies on the functional capacity of the alloplastic spermatocele (Kelâmi-Affeld prosthesis). ( 6760516 )
1982

Variations for Spermatocele

Expression for Spermatocele

Search GEO for disease gene expression data for Spermatocele.

Pathways for Spermatocele

GO Terms for Spermatocele

Cellular components related to Spermatocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection terminus GO:0044306 8.62 MME SYP

Biological processes related to Spermatocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 replicative senescence GO:0090399 8.62 MME TERT

Sources for Spermatocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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