MCID: SPR017
MIFTS: 31

Spermatocele

Categories: Reproductive diseases

Aliases & Classifications for Spermatocele

MalaCards integrated aliases for Spermatocele:

Name: Spermatocele 12 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11997
ICD9CM 35 608.1
MeSH 44 D013088
UMLS 73 C0037859

Summaries for Spermatocele

MalaCards based summary : Spermatocele is related to renal adenoma and esophageal neuroendocrine tumor. An important gene associated with Spermatocele is SLC26A3 (Solute Carrier Family 26 Member 3), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include testis, prostate and kidney.

Wikipedia : 76 Spermatocele (/spɜːrˈmætəsiːl/) is a retention cyst of a tubule of the rete testis or the head of the... more...

Related Diseases for Spermatocele

Diseases related to Spermatocele via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 121)
# Related Disease Score Top Affiliating Genes
1 renal adenoma 10.8 NCAM1 PAX2
2 esophageal neuroendocrine tumor 10.7 NCAM1 SYP
3 hydrocele 10.7
4 ovarian large-cell neuroendocrine carcinoma 10.7 NCAM1 SYP
5 sensory organ benign neoplasm 10.7 NCAM1 SYP
6 gallbladder small cell carcinoma 10.7 NCAM1 SYP
7 cutaneous ganglioneuroma 10.7 NCAM1 SYP
8 orbital cancer 10.7 NCAM1 SYP
9 hypoganglionosis 10.7 NCAM1 SYP
10 pancreatic endocrine carcinoma 10.7 NCAM1 SYP
11 conventional angiosarcoma 10.7 NCAM1 SYP
12 supratentorial primitive neuroectodermal tumor 10.7 NCAM1 SYP
13 endometrial small cell carcinoma 10.6 NCAM1 SYP
14 water-clear cell adenoma 10.6 SYP TG
15 mediastinal cancer 10.6 NCAM1 SYP
16 ureter, cancer of 10.6 SYP TERT
17 kidney benign neoplasm 10.6 MME PAX2
18 angiomyoma 10.6 NCAM1 SYP
19 gastric squamous cell carcinoma 10.6 NCAM1 SYP
20 subependymoma 10.6 NCAM1 SYP
21 malignant teratoma 10.6 SYP TG
22 endometrial mucinous adenocarcinoma 10.5 PAX2 PGR
23 orbital plasma cell granuloma 10.5 MME NCAM1
24 mucinous adenofibroma 10.5 CEACAM5 SYP
25 lung meningioma 10.5 NCAM1 PGR
26 osmotic diarrhea 10.5 MME SLC26A3
27 peroneal neuropathy 10.5 MME TNF
28 sella turcica neoplasm 10.5 PGR SYP
29 gallbladder lymphoma 10.5 CEACAM5 MME
30 adrenal rest tumor 10.5 NCAM1 NR5A1 SYP
31 tuberculum sellae meningioma 10.5 PGR SYP
32 benign breast phyllodes tumor 10.4 MME PGR
33 glycogen-rich clear cell breast carcinoma 10.4 PGR SYP
34 soft tissue sarcoma 10.4 TERT TNF
35 chronic orbital inflammation 10.4 MME NCAM1
36 ovarian lymphoma 10.4 CEACAM5 MME
37 nephrogenic adenofibroma 10.4 MME NCAM1 PAX2
38 cystic nephroma 10.4 MME PGR
39 cervical carcinosarcoma 10.4 MME PGR
40 clear cell adenoma 10.4 CEACAM5 TG
41 acute thyroiditis 10.3 CEACAM5 TG
42 benign meningioma 10.3 PGR TERT
43 lung combined type small cell carcinoma 10.3 MME NCAM1 SYP
44 papillary hidradenoma 10.3 MME PGR
45 granulomatous endometritis 10.3 CEACAM5 PGR
46 endometrial stromal nodule 10.3 MME PGR
47 breast mucoepidermoid carcinoma 10.3 CEACAM5 PGR
48 breast adenomyoepithelioma 10.3 CEACAM5 MME
49 adenosarcoma 10.3 MME PGR
50 intracystic papillary adenoma 10.3 CEACAM5 PGR

Comorbidity relations with Spermatocele via Phenotypic Disease Network (PDN):


Bladder Neck Obstruction Prostate Cancer
Prostatic Hypertrophy

Graphical network of the top 20 diseases related to Spermatocele:



Diseases related to Spermatocele

Symptoms & Phenotypes for Spermatocele

Drugs & Therapeutics for Spermatocele

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy and Safety of DA-9401 on Improvement of Sperm Motility Completed NCT03258437 Not Applicable

Search NIH Clinical Center for Spermatocele

Cochrane evidence based reviews: spermatocele

Genetic Tests for Spermatocele

Anatomical Context for Spermatocele

MalaCards organs/tissues related to Spermatocele:

41
Testis, Prostate, Kidney

Publications for Spermatocele

Articles related to Spermatocele:

(show top 50) (show all 67)
# Title Authors Year
1
131I Whole-Body Scan Incidental Uptake Due to Spermatocele. ( 28902733 )
2017
2
Spermatocele in a South African Boerboel dog. ( 26041595 )
2015
3
Tubular Ectasia of Rete Testis with Spermatocele. ( 26816970 )
2015
4
Routine Pathology Evaluation of Hydrocele and Spermatocele Specimens is Associated with Significant Costs and No Identifiable Benefit. ( 24768992 )
2014
5
Presence of benign germ cells in a fine needle aspirate of a spermatocele. ( 22045691 )
2013
6
Spermatocele following kidney transplant. ( 22487000 )
2012
7
Extra scrotal spermatocele causing lower abdominal pain: a first case report. ( 20674226 )
2011
8
A randomized trial comparing 2 doses of polidocanol sclerotherapy for hydrocele or spermatocele. ( 21849198 )
2011
9
Adult hydrocele and spermatocele. ( 21592287 )
2011
10
Small blue cells mimicking small cell carcinoma in spermatocele and hydrocele specimens: a report of 5 cases. ( 19740515 )
2010
11
Spermiophages in a giant spermatocele. ( 19941373 )
2010
12
Spermatocele presenting as acute scrotum. ( 18825632 )
2008
13
Male fertility after spermatocele formation from tunica vaginalis in patients with bilateral vas agenesis. ( 18580017 )
2008
14
Bilateral spermatocele concurrent with bilateral scrotal hydrocele presenting huge scrotal swelling. ( 18018592 )
2007
15
Giant spermatocele mimicking hydrocele: a case report. ( 17606432 )
2007
16
Theriogenology question of the month. Seminoma, spermatocele, sustentacular cell tumor. ( 15906562 )
2005
17
What causes a spermatocele, and how is it usually removed? ( 15132122 )
2004
18
Spermatocele: a rare complication of rectal surgery and radiotherapy. Case report. ( 15154581 )
2004
19
Retrieval and cryopreservation of sperm from spermatocele fluid. ( 12597959 )
2003
20
Primary bilateral spermatocele. ( 12534930 )
2003
21
Pro-inflammatory cytokine response of the fluid contents of spermatoceles and epididymal cysts. ( 11966578 )
2002
22
Torsion of spermatocele: a rare manifestation. ( 12187053 )
2002
23
Multilocular spermatocele: a case report. ( 11583363 )
2001
24
Spermatocele in a common noctule (Nyctalus noctula). ( 10638800 )
1999
25
Synergistic action of steroids and spermatocele fluid on in vitro proliferation of prostate stroma. ( 9598570 )
1998
26
Intratesticular spermatocele. ( 9610575 )
1998
27
Torsion of spermatocele and aplasia of the vas deferens. A case report. ( 9165262 )
1997
28
Percutaneous sperm aspiration of a spermatocele for intracytoplasmic sperm injection. ( 9302159 )
1997
29
Torsion of a spermatocele. ( 7500478 )
1995
30
Development of a new alloplastic spermatocele demonstrating successful sperm retrieval in an animal model. ( 7789555 )
1995
31
Alloplastic spermatocele: 20 years experience and perspectives. ( 7618373 )
1994
32
Congenital absence of vas deferens treated by artificial spermatocele constructed from the tunica vaginalis; report of six cases. ( 8272538 )
1993
33
Effect of spermatocele fluid on growth of human prostatic cells in culture. ( 8226302 )
1993
34
Clinical experience and successful impregnation using an artificial spermatocele. ( 1771703 )
1991
35
Artificial spermatocele persisting for 14 years. ( 2398578 )
1990
36
Torsion of a spermatocele: a case report and review of the literature. ( 2313807 )
1990
37
In vitro fertilization with spermatozoa from alloplastic spermatocele. ( 2318332 )
1990
38
Implantation of artificial spermatocele with cup-shaped prosthesis for excretory azoospermia and chemical management of aspirated spermatozoa. ( 3745009 )
1986
39
Alloplastic spermatocele: poor sperm motility in intraoperative epididymal fluid contraindicates prosthesis implantation. ( 3735504 )
1986
40
Fertilization of human oocytes by spermatozoa from an artificial spermatocele. ( 3788432 )
1986
41
Alloplastic spermatocele. ( 3735514 )
1986
42
Properties of human epididymal sperm obtained from an alloplastic spermatocele: motility assessment and penetration of zona-free hamster oocytes in the presence and absence of caffeine. ( 4029429 )
1985
43
Torsion of spermatocele: a newly described entity with 2 case reports. ( 3981724 )
1985
44
Alloplastic spermatocele in cases of vasa aplasia. ( 4051632 )
1985
45
A new type of alloplastic spermatocele: the bridge spermatocele. ( 6708803 )
1984
46
Alloplastic spermatocele: diffusion across the allograft material and survival of spermatozoa in vitro and in vivo. ( 6471203 )
1984
47
Clinical experience with an artificial spermatocele. ( 6469865 )
1984
48
Artificial spermatocele inserted onto the vas deferens: a clinical report. ( 6367333 )
1983
49
Outpatient hydrocele and spermatocele repair under local anesthesia. ( 6348308 )
1983
50
KelAcmi-Affeld alloplastic spermatocele and successful human delivery. ( 7324302 )
1981

Variations for Spermatocele

Expression for Spermatocele

Search GEO for disease gene expression data for Spermatocele.

Pathways for Spermatocele

GO Terms for Spermatocele

Cellular components related to Spermatocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection terminus GO:0044306 8.62 MME SYP

Biological processes related to Spermatocele according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 replicative senescence GO:0090399 8.62 MME TERT

Sources for Spermatocele

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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