SPGF25
MCID: SPR128
MIFTS: 20
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Spermatogenic Failure 25 (SPGF25)
Categories:
Genetic diseases, Rare diseases, Reproductive diseases
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MalaCards integrated aliases for Spermatogenic Failure 25:Characteristics:OMIM:56
Inheritance:
autosomal recessive
Miscellaneous:
heterozygous males are fertile, with normal testicular volumes and sperm concentrations HPO:31Classifications: |
OMIM :
56
Spermatogenic failure-25 is characterized by small testes and infertility, with severe oligozoospermia or azoospermia due to maturation arrest at the primary spermatocyte stage (Okutman et al., 2015).
For a general phenotypic description and a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). (617960)
MalaCards based summary : Spermatogenic Failure 25, is also known as spgf25. An important gene associated with Spermatogenic Failure 25 is TEX15 (Testis Expressed 15, Meiosis And Synapsis Associated). Affiliated tissues include testes, and related phenotypes are azoospermia and decreased testicular size UniProtKB/Swiss-Prot : 73 Spermatogenic failure 25: An autosomal recessive infertility disorder caused by spermatogenesis defects that result in severe oligozoospermia or azoospermia. |
Human phenotypes related to Spermatogenic Failure 25:31
Symptoms via clinical synopsis from OMIM:56Clinical features from OMIM:617960 |
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MalaCards organs/tissues related to Spermatogenic Failure 25:40
Testes
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Articles related to Spermatogenic Failure 25:
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ClinVar genetic disease variations for Spermatogenic Failure 25:6
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Search
GEO
for disease gene expression data for Spermatogenic Failure 25.
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