MCID: SPH003
MIFTS: 22

Sphenoorbital Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Sphenoorbital Meningioma

MalaCards integrated aliases for Sphenoorbital Meningioma:

Name: Sphenoorbital Meningioma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7819
NCIt 51 C5285
UMLS 74 C1336040

Summaries for Sphenoorbital Meningioma

MalaCards based summary : Sphenoorbital Meningioma is related to hyperostosis and meningioma, familial, and has symptoms including seizures and headache. An important gene associated with Sphenoorbital Meningioma is KIDINS220 (Kinase D Interacting Substrate 220), and among its related pathways/superpathways are ECM-receptor interaction and Oncogenic MAPK signaling. Affiliated tissues include bone, and related phenotype is cardiovascular system.

Related Diseases for Sphenoorbital Meningioma

Diseases related to Sphenoorbital Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hyperostosis 10.3
2 meningioma, familial 10.1
3 spinal meningioma 10.1
4 secretory meningioma 10.1
5 exophthalmos 10.1

Graphical network of the top 20 diseases related to Sphenoorbital Meningioma:



Diseases related to Sphenoorbital Meningioma

Symptoms & Phenotypes for Sphenoorbital Meningioma

UMLS symptoms related to Sphenoorbital Meningioma:


seizures, headache

MGI Mouse Phenotypes related to Sphenoorbital Meningioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 8.8 FN1 KIDINS220 VWF

Drugs & Therapeutics for Sphenoorbital Meningioma

Search Clinical Trials , NIH Clinical Center for Sphenoorbital Meningioma

Genetic Tests for Sphenoorbital Meningioma

Anatomical Context for Sphenoorbital Meningioma

MalaCards organs/tissues related to Sphenoorbital Meningioma:

42
Bone

Publications for Sphenoorbital Meningioma

Articles related to Sphenoorbital Meningioma:

# Title Authors Year
1
Sphenoorbital meningioma: surgical outcomes and management of recurrence. ( 30844527 )
2019
2
Sphenoorbital meningioma: surgical series and design of an intraoperative management algorithm. ( 28474186 )
2017
3
Bony Hyperostosis Recurrence after Complete Resection of Sphenoorbital Meningioma. ( 28989829 )
2017
4
Combined simultaneous transcranial and endoscopic endonasal resection of sphenoorbital meningioma extending into the sphenoid sinus, pterygopalatine fossa, and infratemporal fossa. ( 28868197 )
2017
5
Delayed Recovery of Visual Acuity after Sphenoorbital Meningioma Surgical Removal: Case Report and Review of the Literature. Is Visual Acuity Recovery Possible after an Initial Decline? ( 25915492 )
2015
6
Severe Edema and Venous Congestion Following Sphenoorbital Meningioma Resection in a Meningiomatosis Case: Importance of Predicting Venous Disturbances. ( 26623234 )
2015
7
Use of the O-armAr for skull base resection in a sphenoorbital meningioma. ( 23664132 )
2013
8
Sphenoorbital meningioma: surgical technique and outcome. ( 21184631 )
2011

Variations for Sphenoorbital Meningioma

Expression for Sphenoorbital Meningioma

Search GEO for disease gene expression data for Sphenoorbital Meningioma.

Pathways for Sphenoorbital Meningioma

Pathways related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.33 FN1 VWF
2
Show member pathways
11.09 FN1 VWF
3
Show member pathways
10.61 FN1 VWF

GO Terms for Sphenoorbital Meningioma

Cellular components related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen-containing extracellular matrix GO:0062023 8.96 FN1 VWF
2 extracellular matrix GO:0031012 8.85 FN1
3 platelet alpha granule lumen GO:0031093 8.62 FN1 VWF

Biological processes related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.16 FN1 VWF
2 platelet degranulation GO:0002576 8.96 FN1 VWF
3 response to wounding GO:0009611 8.62 FN1 VWF

Molecular functions related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrin binding GO:0005178 9.32 FN1 VWF
2 extracellular matrix structural constituent GO:0005201 9.26 FN1 VWF
3 chaperone binding GO:0051087 9.16 FN1 VWF
4 protease binding GO:0002020 8.96 FN1 VWF
5 collagen binding GO:0005518 8.62 FN1 VWF

Sources for Sphenoorbital Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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