MCID: SPH003
MIFTS: 20

Sphenoorbital Meningioma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Sphenoorbital Meningioma

MalaCards integrated aliases for Sphenoorbital Meningioma:

Name: Sphenoorbital Meningioma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7819
NCIt 50 C5285
UMLS 71 C1336040

Summaries for Sphenoorbital Meningioma

MalaCards based summary : Sphenoorbital Meningioma is related to meningioma, familial and spinal meningioma, and has symptoms including seizures and headache. An important gene associated with Sphenoorbital Meningioma is NF2 (Neurofibromin 2), and among its related pathways/superpathways is Mucin type O-glycan biosynthesis. Related phenotype is renal/urinary system.

Related Diseases for Sphenoorbital Meningioma

Diseases related to Sphenoorbital Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 meningioma, familial 10.5
2 spinal meningioma 10.5
3 secretory meningioma 10.5
4 lymphoplasmacyte-rich meningioma 10.5
5 exophthalmos 10.5
6 hyperostosis 10.4
7 enophthalmos 10.0
8 optic nerve disease 10.0
9 scotoma 10.0
10 posttransplant acute limbic encephalitis 10.0
11 myeloproliferative syndrome, transient 9.5 NF2 ITGB3

Graphical network of the top 20 diseases related to Sphenoorbital Meningioma:



Diseases related to Sphenoorbital Meningioma

Symptoms & Phenotypes for Sphenoorbital Meningioma

UMLS symptoms related to Sphenoorbital Meningioma:


seizures, headache

MGI Mouse Phenotypes related to Sphenoorbital Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 FOXD2 GALNT13 ITGB3 NF2 TMEM30B

Drugs & Therapeutics for Sphenoorbital Meningioma

Search Clinical Trials , NIH Clinical Center for Sphenoorbital Meningioma

Genetic Tests for Sphenoorbital Meningioma

Anatomical Context for Sphenoorbital Meningioma

Publications for Sphenoorbital Meningioma

Articles related to Sphenoorbital Meningioma:

(show all 18)
# Title Authors PMID Year
1
Orbital decompressive effect of endoscopic transorbital surgery for sphenoorbital meningioma. 61
33226438 2020
2
Use of endoscopic transorbital and endonasal approaches for 360° circumferential access to orbital tumors. 61
32977310 2020
3
Resection of Invasive Sphenoorbital and Cavernous Sinus Meningioma via Frontotemporal Craniotomy. 61
32416238 2020
4
Single-Step Resection of Sphenoorbital Meningiomas and Orbital Reconstruction Using Customized CAD/CAM Implants. 61
32206532 2020
5
Sphenoorbital meningioma: a unique skull base tumor. Surgical technique and results. 61
31443076 2019
6
Sphenoorbital meningioma: surgical series and design of an intraoperative management algorithm. 61
28474186 2018
7
Bony Hyperostosis Recurrence after Complete Resection of Sphenoorbital Meningioma. 61
28989829 2017
8
Combined simultaneous transcranial and endoscopic endonasal resection of sphenoorbital meningioma extending into the sphenoid sinus, pterygopalatine fossa, and infratemporal fossa. 61
28868197 2017
9
Severe Edema and Venous Congestion Following Sphenoorbital Meningioma Resection in a Meningiomatosis Case: Importance of Predicting Venous Disturbances. 61
26623234 2015
10
Delayed Recovery of Visual Acuity after Sphenoorbital Meningioma Surgical Removal: Case Report and Review of the Literature. Is Visual Acuity Recovery Possible after an Initial Decline? 61
25915492 2015
11
Sphenoorbital meningiomas: surgical management and outcome. 61
24620980 2014
12
Surgical strategies for the removal of sphenoorbital meningiomas. 61
25448201 2014
13
Endoscopic endonasal optic nerve and orbital apex decompression for nontraumatic optic neuropathy: surgical nuances and review of the literature. 61
25270138 2014
14
Use of the O-arm® for skull base resection in a sphenoorbital meningioma. 61
23664132 2013
15
Bilateral sphenoorbital hyperostotic meningiomas with proptosis and visual impairment: a therapeutic challenge. Report of three patients and review of the literature. 61
21782319 2011
16
Surgical treatment of sphenoorbital meningiomas. 61
21242579 2011
17
Sphenoorbital meningioma: surgical technique and outcome. 61
21184631 2011
18
Long-term results with exophthalmos in a surgical series of 30 sphenoorbital meningiomas. Clinical article. 61
19267523 2009

Variations for Sphenoorbital Meningioma

Expression for Sphenoorbital Meningioma

Search GEO for disease gene expression data for Sphenoorbital Meningioma.

Pathways for Sphenoorbital Meningioma

Pathways related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.64 GALNT15 GALNT13

GO Terms for Sphenoorbital Meningioma

Cellular components related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ruffle membrane GO:0032587 8.96 NF2 ITGB3
2 filopodium membrane GO:0031527 8.62 NF2 ITGB3

Biological processes related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anatomical structure morphogenesis GO:0009653 9.16 FOXE3 FOXD2
2 O-glycan processing GO:0016266 8.96 GALNT15 GALNT13
3 protein phosphopantetheinylation GO:0018215 8.8 ITGB3 GALNT15 GALNT13

Molecular functions related to Sphenoorbital Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 polypeptide N-acetylgalactosaminyltransferase activity GO:0004653 8.62 GALNT15 GALNT13

Sources for Sphenoorbital Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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