Spinal Canal and Spinal Cord Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Spinal Canal and Spinal Cord Meningioma

MalaCards integrated aliases for Spinal Canal and Spinal Cord Meningioma:

Name: Spinal Canal and Spinal Cord Meningioma ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:1140

NCIt ⁵⁰ C5134

UMLS ⁷³ C1334264

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Summaries for Spinal Canal and Spinal Cord Meningioma

MalaCards based summary : Spinal Canal and Spinal Cord Meningioma is related to thoracic spinal canal and spinal cord meningioma and lumbar spinal canal and spinal cord meningioma. An important gene associated with Spinal Canal and Spinal Cord Meningioma is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Gastric cancer and Glioblastoma Multiforme. Affiliated tissues include spinal cord, lung and kidney, and related phenotypes are endocrine/exocrine gland and growth/size/body region

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Related Diseases for Spinal Canal and Spinal Cord Meningioma

Diseases in the Spinal Canal and Spinal Cord Meningioma family:

Multiple Spinal Canal and Spinal Cord Meningioma

Diseases related to Spinal Canal and Spinal Cord Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 95)

#	Related Disease	Score	Top Affiliating Genes
1	thoracic spinal canal and spinal cord meningioma	12.6
2	lumbar spinal canal and spinal cord meningioma	12.6
3	multiple spinal canal and spinal cord meningioma	12.6
4	cervical spinal canal and spinal cord meningioma	12.6
5	sacral spinal canal and spinal cord meningioma	12.6
6	neurofibromatosis, familial spinal	10.2	NF1 NF2
7	lymphoplasmacyte-rich meningioma	10.2	MIB1 PGR
8	immature cataract	10.2	NF1 NF2
9	neurofibrosarcoma	10.2	NF1 NF2
10	plexiform neurofibroma	10.2	NF1 NF2
11	trigeminal nerve neoplasm	10.2	NF1 NF2
12	neurilemmoma of the fifth cranial nerve	10.2	NF1 NF2
13	small cell sarcoma	10.2	NF2 SOX10
14	tanycytic ependymoma	10.2	CHGA NF2
15	meningocele	10.2	HSF4 NF1
16	pancreatic serous cystadenoma	10.2	CHGA PGR
17	malignant spindle cell melanoma	10.1	NF1 SOX10
18	benign meningioma	10.1	NF2 PGR SMARCE1
19	benign ependymoma	10.1	ENO2 NF2
20	neurilemmomatosis	10.1	NF1 NF2 SMARCE1
21	pilocytic astrocytoma	10.1	NF1 SOX10
22	olfactory groove meningioma	10.1	CHGA NF2 PGR
23	malignant granular cell myoblastoma	10.1	ENO2 SOX10
24	dermoid cyst	10.1	CHGA PGR
25	spinal cancer	10.1	CYP4F22 FAT2 HSF4 NF2
26	insulinomatosis and diabetes mellitus	10.1	CHGA IGF2
27	anterior cranial fossa meningioma	10.1	CHGA NF2 PGR
28	malignant peripheral nerve sheath tumor	10.1	NF1 NF2 SOX10
29	lung meningioma	10.1	ENO2 PGR
30	atypical neurofibroma	10.1	NF1 NF2 SOX10
31	neurofibroma	10.1	NF1 NF2 SOX10
32	sclerosing hemangioma	10.1	CHGA PGR
33	cellular schwannoma	10.1	NF1 NF2 SOX10
34	clear cell meningioma	10.1	CHGA PGR SMARCE1
35	epulis	10.1	ENO2 PGR
36	urinary bladder small cell neuroendocrine carcinoma	10.1	CHGA ENO2
37	intracranial primitive neuroectodermal tumor	10.1	CHGA ENO2
38	auditory system cancer	10.1	CHGA ENO2
39	gallbladder small cell carcinoma	10.1	CHGA ENO2
40	small cell carcinoma of the bladder	10.1	CHGA ENO2
41	somatostatinoma	10.1	CHGA ENO2
42	lung oat cell carcinoma	10.1	CHGA ENO2
43	pulmonary large cell neuroendocrine carcinoma	10.1	CHGA ENO2
44	goblet cell carcinoid	10.1	CHGA ENO2
45	meningothelial meningioma	10.1	ENO2 NF2 SMARCE1
46	olfactory nerve neoplasm	10.1	CHGA ENO2
47	cervical clear cell adenocarcinoma	10.1	ENO2 PGR
48	duodenal somatostatinoma	10.1	ENO2 NF1
49	nodular ganglioneuroblastoma	10.0	CHGA ENO2
50	pineocytoma	10.0	CHGA ENO2

Graphical network of the top 20 diseases related to Spinal Canal and Spinal Cord Meningioma:

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Symptoms & Phenotypes for Spinal Canal and Spinal Cord Meningioma

MGI Mouse Phenotypes related to Spinal Canal and Spinal Cord Meningioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.76	CHGA IGF2 MIB1 NF1 NF2 PGR
2	growth/size/body region	MP:0005378	9.61	CHGA ENO2 GFER IGF2 MIB1 NF1
3	limbs/digits/tail	MP:0005371	9.1	IGF2 MIB1 NF1 PGR SOX10 TG

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Drugs & Therapeutics for Spinal Canal and Spinal Cord Meningioma

Search Clinical Trials , NIH Clinical Center for Spinal Canal and Spinal Cord Meningioma

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Genetic Tests for Spinal Canal and Spinal Cord Meningioma

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Anatomical Context for Spinal Canal and Spinal Cord Meningioma

MalaCards organs/tissues related to Spinal Canal and Spinal Cord Meningioma:

⁴¹

Spinal Cord, Lung, Kidney, Ovary, Cervix, Thyroid, Pineal

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Publications for Spinal Canal and Spinal Cord Meningioma

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Genes for Spinal Canal and Spinal Cord Meningioma

Genes related to Spinal Canal and Spinal Cord Meningioma (0 elite genes):

(show all 15)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NF2	Neurofibromin 2	Protein Coding	16.6	DISEASES inferred ¹⁵
2	FAT2	FAT Atypical Cadherin 2	Protein Coding	16.03	DISEASES inferred ¹⁵
3	CYP4F22	Cytochrome P450 Family 4 Subfamily F Member 22	Protein Coding	16.01	DISEASES inferred ¹⁵
4	SMARCE1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1	Protein Coding	15.6	DISEASES inferred ¹⁵
5	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	15.28	DISEASES inferred ¹⁵
6	HSF4	Heat Shock Transcription Factor 4	Protein Coding	14.89	DISEASES inferred ¹⁵
7	MIB1	Mindbomb E3 Ubiquitin Protein Ligase 1	Protein Coding	14.63	DISEASES inferred ¹⁵
8	SOX10	SRY-Box 10	Protein Coding	14.36	DISEASES inferred ¹⁵
9	PGR	Progesterone Receptor	Protein Coding	14.27	DISEASES inferred ¹⁵
10	CHGA	Chromogranin A	Protein Coding	13.41	DISEASES inferred ¹⁵
11	NF1	Neurofibromin 1	Protein Coding	13.19	DISEASES inferred ¹⁵
12	IGF2	Insulin Like Growth Factor 2	Protein Coding	13.18	DISEASES inferred ¹⁵
13	ENO2	Enolase 2	Protein Coding	13.1	DISEASES inferred ¹⁵
14	TG	Thyroglobulin	Protein Coding	12.98	DISEASES inferred ¹⁵
15	CDH17	Cadherin 17	Protein Coding	3.66	DISEASES inferred ¹⁵

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Variations for Spinal Canal and Spinal Cord Meningioma

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Expression for Spinal Canal and Spinal Cord Meningioma

Search GEO for disease gene expression data for Spinal Canal and Spinal Cord Meningioma.

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Pathways for Spinal Canal and Spinal Cord Meningioma

Pathways related to Spinal Canal and Spinal Cord Meningioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	11.92	CDH17 IGF2 PGR SMARCE1
2	Glioblastoma Multiforme ⁶⁴	10.84	IGF2 NF1 NF2

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GO Terms for Spinal Canal and Spinal Cord Meningioma

Biological processes related to Spinal Canal and Spinal Cord Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	peripheral nervous system development	GO:0007422	9.16	NF1 SOX10
2	negative regulation of MAPK cascade	GO:0043409	8.96	NF1 NF2
3	negative regulation of cell-matrix adhesion	GO:0001953	8.62	NF1 NF2

Molecular functions related to Spinal Canal and Spinal Cord Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	RNA polymerase II proximal promoter sequence-specific DNA binding	GO:0000978	8.92	HSF4 PGR SMARCE1 SOX10

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Sources for Spinal Canal and Spinal Cord Meningioma

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⁷¹ TGDB

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⁷⁶ Wikipedia