Spinal Canal and Spinal Cord Meningioma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Spinal Canal and Spinal Cord Meningioma

MalaCards integrated aliases for Spinal Canal and Spinal Cord Meningioma:

Name: Spinal Canal and Spinal Cord Meningioma ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:1140

NCIt ⁵⁰ C5134

UMLS ⁷³ C1334264

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Summaries for Spinal Canal and Spinal Cord Meningioma

MalaCards based summary : Spinal Canal and Spinal Cord Meningioma is related to thoracic spinal canal and spinal cord meningioma and lumbar spinal canal and spinal cord meningioma. An important gene associated with Spinal Canal and Spinal Cord Meningioma is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Gastric cancer and Glioblastoma Multiforme. Affiliated tissues include spinal cord, and related phenotype is endocrine/exocrine gland.

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Related Diseases for Spinal Canal and Spinal Cord Meningioma

Diseases in the Spinal Canal and Spinal Cord Meningioma family:

Multiple Spinal Canal and Spinal Cord Meningioma

Diseases related to Spinal Canal and Spinal Cord Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)

#	Related Disease	Score	Top Affiliating Genes
1	thoracic spinal canal and spinal cord meningioma	12.4
2	lumbar spinal canal and spinal cord meningioma	12.4
3	multiple spinal canal and spinal cord meningioma	12.4
4	cervical spinal canal and spinal cord meningioma	12.4
5	sacral spinal canal and spinal cord meningioma	12.4
6	optic nerve sheath meningioma	10.7	NF2 SAMHD1
7	lymphoplasmacyte-rich meningioma	10.7	MIB1 PGR
8	tanycytic ependymoma	10.7	CHGA NF2
9	neurofibromatosis, familial spinal	10.6	NF1 NF2
10	pancreatic serous cystadenoma	10.6	CHGA PGR
11	neurofibrosarcoma	10.6	NF1 NF2
12	immature cataract	10.5	NF1 NF2
13	plexiform neurofibroma	10.5	NF1 NF2
14	atypical neurofibroma	10.5	NF1 NF2
15	benign meningioma	10.5	NF2 PGR SMARCE1
16	dermoid cyst	10.5	CHGA PGR
17	meningocele	10.5	HSF4 NF1
18	hyperinsulinemic hypoglycemia, familial, 2	10.5	CHGA IGF2
19	benign ependymoma	10.4	ENO2 NF2
20	olfactory groove meningioma	10.4	CHGA NF2 PGR
21	anterior cranial fossa meningioma	10.4	CHGA NF2 PGR
22	clear cell meningioma	10.4	CHGA PGR SMARCE1
23	epulis	10.3	ENO2 PGR
24	spinal cancer	10.3	CYP4F22 FAT2 HSF4 NF2
25	ureter small cell carcinoma	10.3	CHGA ENO2
26	urinary bladder small cell neuroendocrine carcinoma	10.3	CHGA ENO2
27	intracranial primitive neuroectodermal tumor	10.3	CHGA ENO2
28	neurilemmomatosis	10.3	NF1 NF2 SMARCE1
29	auditory system cancer	10.3	CHGA ENO2
30	gallbladder small cell carcinoma	10.3	CHGA ENO2
31	small cell carcinoma of the bladder	10.3	CHGA ENO2
32	pulmonary large cell neuroendocrine carcinoma	10.3	CHGA ENO2
33	goblet cell carcinoid	10.3	CHGA ENO2
34	olfactory nerve neoplasm	10.3	CHGA ENO2
35	nodular ganglioneuroblastoma	10.2	CHGA ENO2
36	pineocytoma	10.2	CHGA ENO2
37	respiratory system benign neoplasm	10.2	CHGA ENO2
38	cervical clear cell adenocarcinoma	10.2	ENO2 PGR
39	gastric squamous cell carcinoma	10.2	CHGA ENO2
40	gastric small cell carcinoma	10.2	CHGA ENO2
41	subependymoma	10.2	CHGA ENO2
42	meningothelial meningioma	10.2	ENO2 NF2 SMARCE1
43	carcinoid tumors, intestinal	10.2	CHGA ENO2
44	somatostatinoma	10.2	CHGA ENO2
45	hypotropia	10.2	NF1 SAMHD1
46	gastric leiomyosarcoma	10.2	ENO2 IGF2
47	cerebellopontine angle tumor	10.2	NF2 SAMHD1
48	papillary ependymoma	10.2	CHGA ENO2
49	cerebral neuroblastoma	10.2	ENO2 IGF2
50	duodenal gastrinoma	10.2	CHGA ENO2

Graphical network of the top 20 diseases related to Spinal Canal and Spinal Cord Meningioma:

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Symptoms & Phenotypes for Spinal Canal and Spinal Cord Meningioma

MGI Mouse Phenotypes related to Spinal Canal and Spinal Cord Meningioma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland	MP:0005379	9.17	TG CHGA IGF2 MIB1 NF1 NF2

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Drugs & Therapeutics for Spinal Canal and Spinal Cord Meningioma

Search Clinical Trials , NIH Clinical Center for Spinal Canal and Spinal Cord Meningioma

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Genetic Tests for Spinal Canal and Spinal Cord Meningioma

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Anatomical Context for Spinal Canal and Spinal Cord Meningioma

MalaCards organs/tissues related to Spinal Canal and Spinal Cord Meningioma:

⁴¹

Spinal Cord

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Publications for Spinal Canal and Spinal Cord Meningioma

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Genes for Spinal Canal and Spinal Cord Meningioma

Genes related to Spinal Canal and Spinal Cord Meningioma (0 elite genes):

(show all 15)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NF2	Neurofibromin 2	Protein Coding	16.68	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	FAT2	FAT Atypical Cadherin 2	Protein Coding	16.17	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	CYP4F22	Cytochrome P450 Family 4 Subfamily F Member 22	Protein Coding	16.1	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	SMARCE1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily E, Member 1	Protein Coding	15.76	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	GFER	Growth Factor, Augmenter Of Liver Regeneration	Protein Coding	15.41	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	HSF4	Heat Shock Transcription Factor 4	Protein Coding	14.93	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	MIB1	Mindbomb E3 Ubiquitin Protein Ligase 1	Protein Coding	14.76	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	PGR	Progesterone Receptor	Protein Coding	14.39	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	CHGA	Chromogranin A	Protein Coding	13.54	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	SAMHD1	SAM And HD Domain Containing Deoxynucleoside Triphosphate Triphosphohydrolase 1	Protein Coding	13.39	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	IGF2	Insulin Like Growth Factor 2	Protein Coding	13.29	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	NF1	Neurofibromin 1	Protein Coding	13.25	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	ENO2	Enolase 2	Protein Coding	13.24	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
14	TG	Thyroglobulin	Protein Coding	13.08	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
15	CDH17	Cadherin 17	Protein Coding	3.8	DISEASES inferred ¹⁵

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Variations for Spinal Canal and Spinal Cord Meningioma

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Expression for Spinal Canal and Spinal Cord Meningioma

Search GEO for disease gene expression data for Spinal Canal and Spinal Cord Meningioma.

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Pathways for Spinal Canal and Spinal Cord Meningioma

Pathways related to Spinal Canal and Spinal Cord Meningioma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	11.92	CDH17 IGF2 PGR SMARCE1
2	Glioblastoma Multiforme ⁶⁴	10.84	IGF2 NF1 NF2

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GO Terms for Spinal Canal and Spinal Cord Meningioma

Biological processes related to Spinal Canal and Spinal Cord Meningioma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of MAPK cascade	GO:0043409	8.96	NF1 NF2
2	negative regulation of cell-matrix adhesion	GO:0001953	8.62	NF1 NF2

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Sources for Spinal Canal and Spinal Cord Meningioma

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