Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: SPN013
MIFTS: 21

Spinal Canal Intradural Extramedullary Neoplasm

Categories: Cancer diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways
Sources

Aliases & Classifications for Spinal Canal Intradural Extramedullary Neoplasm

About this section

MalaCards integrated aliases for Spinal Canal Intradural Extramedullary Neoplasm:

Name: Spinal Canal Intradural Extramedullary Neoplasm 12 15
Intradural Extramedullary Spinal Canal Neoplasm 71
Intradural Extramedullary Spinal Tumors 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:5615
NCIt 49 C5135
UMLS 71 C1334255
Sources

Summaries for Spinal Canal Intradural Extramedullary Neoplasm

About this section
MalaCards based summary : Spinal Canal Intradural Extramedullary Neoplasm, also known as intradural extramedullary spinal canal neoplasm, is related to spinal meningioma and neurofibromatosis, type iv, of riccardi. An important gene associated with Spinal Canal Intradural Extramedullary Neoplasm is ZNF398 (Zinc Finger Protein 398), and among its related pathways/superpathways are Hippo signaling pathway and Hippo signaling pathway - multiple species. Affiliated tissues include brain and spinal cord, and related phenotypes are Decreased p24 protein expression and Decreased Tat-dependent transcription

Sources

Related Diseases for Spinal Canal Intradural Extramedullary Neoplasm

About this section

Diseases related to Spinal Canal Intradural Extramedullary Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 spinal meningioma 30.2 NF2 DCAF1
2 neurofibromatosis, type iv, of riccardi 29.9 NF2 DCAF1
3 meningioma, radiation-induced 10.4
4 meningioma, familial 10.4
5 secretory meningioma 10.4
6 lymphoplasmacyte-rich meningioma 10.4
7 neurilemmoma 10.3
8 neurofibroma 10.3
9 pik3ca-related overgrowth syndrome 10.3
10 rare surgical neurologic disease 10.2
11 radiculopathy 10.1
12 paraplegia 10.1
13 cerebrospinal fluid leak 10.1
14 rosai-dorfman disease 10.1
15 intraorbital meningioma 9.8 NF2 DCAF1
16 brain meningioma 9.8 NF2 DCAF1
17 spinal canal and spinal cord meningioma 9.8 NF2 DCAF1
18 neurilemmomatosis 9.7 NF2 DCAF1
19 wilson-turner x-linked mental retardation syndrome 9.4 NF2 FRMD6

Graphical network of the top 20 diseases related to Spinal Canal Intradural Extramedullary Neoplasm:



Diseases related to Spinal Canal Intradural Extramedullary Neoplasm
Sources

Symptoms & Phenotypes for Spinal Canal Intradural Extramedullary Neoplasm

About this section

GenomeRNAi Phenotypes related to Spinal Canal Intradural Extramedullary Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased p24 protein expression GR00163-A-1 9.13 AGAP2 DCAF1 NF2
2 Decreased Tat-dependent transcription GR00163-A-2 8.62 AGAP2 NF2
Sources

Drugs & Therapeutics for Spinal Canal Intradural Extramedullary Neoplasm

About this section

Search Clinical Trials , NIH Clinical Center for Spinal Canal Intradural Extramedullary Neoplasm

Sources

Genetic Tests for Spinal Canal Intradural Extramedullary Neoplasm

About this section
Sources

Anatomical Context for Spinal Canal Intradural Extramedullary Neoplasm

About this section

MalaCards organs/tissues related to Spinal Canal Intradural Extramedullary Neoplasm:

40
Brain, Spinal Cord
Sources

Publications for Spinal Canal Intradural Extramedullary Neoplasm

About this section

Articles related to Spinal Canal Intradural Extramedullary Neoplasm:

(show all 37)
# Title Authors PMID Year
1
Minimally Invasive Resection of a Cervical Anterolateral Meningioma: 2-Dimensional Operative Video. 61
30060214 2019
2
Vitom 3D: preliminary experience with intradural extramedullary spinal tumors. 61
30942053 2019
3
Age Is a Risk Factor for Postoperative Complications Following Excisional Laminectomy for Intradural Extramedullary Spinal Tumors. 61
30984489 2019
4
Predictors of Discharge Disposition Following Laminectomy for Intradural Extramedullary Spinal Tumors. 61
30500579 2019
5
Diagnostic and therapeutic values of intraoperative electrophysiological neuromonitoring during resection of intradural extramedullary spinal tumors: a single-center retrospective cohort and meta-analysis. 61
30835707 2019
6
Differentiating spinal intradural-extramedullary schwannoma from meningioma using MRI T2 weighted images. 61
30052467 2018
7
Intraoperative neurophysiological monitoring for intradural extramedullary spinal tumors: predictive value and relevance of D-wave amplitude on surgical outcome during a 10-year experience. 61
30497134 2018
8
[Comparison of open and minimally invasive techniques in the surgical treatment of intradural extramedullary spinal tumors in elderly and senile patients.] 61
30584881 2018
9
Healthcare Resource Utilization and Patient-Reported Outcomes Following Elective Surgery for Intradural Extramedullary Spinal Tumors. 61
28498938 2017
10
[Neurosurgical Outcomes of Intradural Extramedullary Spinal Tumors in 97 cases:Siberian Experience]. 61
28924067 2017
11
Surgical management of ventrally located spinal meningiomas via posterior approach. 61
27671472 2017
12
Lumbar chronic subdural hematoma mimicking an intradural extramedullary tumor: A case report. 61
29026667 2017
13
Surgical Resection of Intradural Extramedullary Spinal Tumors: Patient Reported Outcomes and Minimum Clinically Important Difference. 61
27111764 2016
14
Improved patient quality of life following intradural extramedullary spinal tumor resection. 61
27341053 2016
15
Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat. 61
26645333 2016
16
Postoperative Functional Outcome of Intradural Extramedullary Spinal Tumors Through Posterior Approach. 61
26876398 2016
17
Comparison of minimally invasive transspinous and open approaches for thoracolumbar intradural-extramedullary spinal tumors. 61
26235010 2015
18
Hemilaminectomy approach for intradural extramedullary spinal tumors: an analysis of 164 patients. 61
26235026 2015
19
Meningeal relationships to the spinal nerves and rootlets: a gross, histological, and radiological study with application to intradural extramedullary spinal tumors. 61
25686899 2015
20
Minimally invasive surgery for synchronous, same-level lumbar intradural-extramedullary neoplasm and acute disc herniation. 61
25175577 2014
21
Complication avoidance in intradural extramedullary spinal tumors. 61
24702506 2014
22
Cystic spinal schwannomas: A short series of six cases. Can we predict them preoperatively? 61
25289159 2014
23
Anatomical location dictating major surgical complications for intradural extramedullary spinal tumors: a 10-year single-institutional experience. 61
24116680 2013
24
A case of intradural osteosarcoma of the spine. 61
23578988 2013
25
Intradural extramedullary spinal ependymoma: a case report of malignant transformation occurring. 61
23741554 2013
26
Radiologic-pathologic correlation of pediatric and adolescent spinal neoplasms: Part 2, Intradural extramedullary spinal neoplasms. 61
22194478 2012
27
Stereotactic radiosurgery yields long-term control for benign intradural, extramedullary spinal tumors. 61
21832967 2011
28
A long-segment string of bead- like schwannoma of cauda equina: a case report. 61
20963708 2010
29
Multiple intradural-extramedullary ependymomas: proven dissemination by genetic analysis. 61
20433294 2010
30
Totally cystic intradural extramedullary schwannoma. 61
19107689 2008
31
Radiosurgery for benign intradural spinal tumors. 61
18496194 2008
32
Thoracic intradural cystic schwannoma: a case report. 61
17939106 2007
33
CyberKnife radiosurgery for benign intradural extramedullary spinal tumors. 61
16575331 2006
34
MRI of intradural-extramedullary spinal neurinomas and meningiomas. 61
8439845 1993
35
MR imaging of intradural extramedullary tumors. 61
1591121 1992
36
[Two cases of von Recklinghausen's disease with multiple brain and spinal tumors]. 61
1738426 1992
37
CT myelography for differential diagnosis between intramedullary and intradural-extramedullary spinal tumors in the region of the conus medullaris. 61
1679112 1991
Sources

Variations for Spinal Canal Intradural Extramedullary Neoplasm

About this section
Sources

Expression for Spinal Canal Intradural Extramedullary Neoplasm

About this section
Search GEO for disease gene expression data for Spinal Canal Intradural Extramedullary Neoplasm.
Sources

Pathways for Spinal Canal Intradural Extramedullary Neoplasm

About this section

Pathways related to Spinal Canal Intradural Extramedullary Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Hippo signaling pathway 36
11.14 NF2 FRMD6
2
Hippo signaling pathway - multiple species 36
10.09 NF2 FRMD6
Sources

GO Terms for Spinal Canal Intradural Extramedullary Neoplasm

About this section
Sources

Sources for Spinal Canal Intradural Extramedullary Neoplasm

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....