Spinal Cord Dermoid Cyst disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Spinal Cord Dermoid Cyst

MalaCards integrated aliases for Spinal Cord Dermoid Cyst:

Name: Spinal Cord Dermoid Cyst ¹² ¹⁵

Dermoid Cyst of the Spinal Cord ⁷¹

Spinal Cord Dermoid ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7071

NCIt ⁴⁹ C6808

UMLS ⁷¹ C1333278

Sources

Summaries for Spinal Cord Dermoid Cyst

Disease Ontology : ¹² A dermoid cyst that is located in the spinal cord.

MalaCards based summary : Spinal Cord Dermoid Cyst, also known as dermoid cyst of the spinal cord, is related to epidermoid cysts and leigh syndrome. An important gene associated with Spinal Cord Dermoid Cyst is NDUFS2 (NADH:Ubiquinone Oxidoreductase Core Subunit S2), and among its related pathways/superpathways are GABAergic synapse and Metformin Pathway, Pharmacodynamics. Affiliated tissues include spinal cord and liver.

Sources

Related Diseases for Spinal Cord Dermoid Cyst

Diseases related to Spinal Cord Dermoid Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	epidermoid cysts	10.0
2	leigh syndrome	9.6	NDUFS4 NDUFS2
3	leigh syndrome with leukodystrophy	9.6	NDUFS4 NDUFS2
4	leukodystrophy	9.6	NDUFS4 NDUFS2
5	mitochondrial disorders	9.6	NDUFS4 NDUFS2
6	leber optic atrophy	9.5	NDUFS4 NDUFS2
7	mitochondrial complex i deficiency, nuclear type 1	9.5	NDUFS4 NDUFS2
8	mitochondrial metabolism disease	9.4	NDUFS4 NDUFS2
9	liver disease	9.2	NDUFS4 NDUFS2

Graphical network of the top 20 diseases related to Spinal Cord Dermoid Cyst:

Sources

Symptoms & Phenotypes for Spinal Cord Dermoid Cyst

Sources

Drugs & Therapeutics for Spinal Cord Dermoid Cyst

Search Clinical Trials , NIH Clinical Center for Spinal Cord Dermoid Cyst

Sources

Genetic Tests for Spinal Cord Dermoid Cyst

Sources

Anatomical Context for Spinal Cord Dermoid Cyst

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Cord Dermoid Cyst:

¹⁹

Spinal Cord

MalaCards organs/tissues related to Spinal Cord Dermoid Cyst:

⁴⁰

Spinal Cord, Liver

Sources

Publications for Spinal Cord Dermoid Cyst

Articles related to Spinal Cord Dermoid Cyst:

#	Title	Authors	PMID	Year
1	Spectrum of Complications in a Case of Intramedullary Dermoid. ⁶¹	Kumar S...Dhurvey D	31917306	2020

Sources

Genes for Spinal Cord Dermoid Cyst

Genes related to Spinal Cord Dermoid Cyst (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	NDUFS2	NADH:Ubiquinone Oxidoreductase Core Subunit S2	Protein Coding	6.07	DISEASES inferred ¹⁵
2	NDUFS4	NADH:Ubiquinone Oxidoreductase Subunit S4	Protein Coding	5.65	DISEASES inferred ¹⁵

Sources

Variations for Spinal Cord Dermoid Cyst

Sources

Expression for Spinal Cord Dermoid Cyst

Search GEO for disease gene expression data for Spinal Cord Dermoid Cyst.

Sources

Pathways for Spinal Cord Dermoid Cyst

Pathways related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	GABAergic synapse ³⁶ Show member pathways Morphine addiction ³⁶ Retrograde endocannabinoid signaling ³⁶	11.47	NDUFS4 NDUFS2
2	Metformin Pathway, Pharmacodynamics ⁶⁰	10.18	NDUFS4 NDUFS2

Sources

GO Terms for Spinal Cord Dermoid Cyst

Cellular components related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mitochondrial inner membrane	GO:0005743	9.16	NDUFS4 NDUFS2
2	respiratory chain	GO:0070469	8.96	NDUFS4 NDUFS2
3	mitochondrial respiratory chain complex I	GO:0005747	8.62	NDUFS4 NDUFS2

Biological processes related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	oxidation-reduction process	GO:0055114	9.16	NDUFS4 NDUFS2
2	mitochondrial respiratory chain complex I assembly	GO:0032981	8.96	NDUFS4 NDUFS2
3	mitochondrial electron transport, NADH to ubiquinone	GO:0006120	8.62	NDUFS4 NDUFS2

Molecular functions related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	NADH dehydrogenase (ubiquinone) activity	GO:0008137	8.96	NDUFS4 NDUFS2
2	oxidoreductase activity, acting on NAD(P)H	GO:0016651	8.62	NDUFS4 NDUFS2

Sources

Sources for Spinal Cord Dermoid Cyst

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia