Spinal Cord Dermoid Cyst disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Spinal Cord Dermoid Cyst

MalaCards integrated aliases for Spinal Cord Dermoid Cyst:

Name: Spinal Cord Dermoid Cyst ¹² ¹⁵

Dermoid Cyst of the Spinal Cord ⁷¹

Spinal Cord Dermoid ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7071

NCIt ⁴⁹ C6808

UMLS ⁷¹ C1333278

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Summaries for Spinal Cord Dermoid Cyst

Disease Ontology : ¹² A dermoid cyst that is located in the spinal cord.

MalaCards based summary : Spinal Cord Dermoid Cyst, also known as dermoid cyst of the spinal cord, is related to leigh syndrome and leigh syndrome with leukodystrophy. An important gene associated with Spinal Cord Dermoid Cyst is NDUFS2 (NADH:Ubiquinone Oxidoreductase Core Subunit S2), and among its related pathways/superpathways are Parkinson disease and GABAergic synapse. Affiliated tissues include spinal cord.

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Related Diseases for Spinal Cord Dermoid Cyst

Diseases related to Spinal Cord Dermoid Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	leigh syndrome	9.6	NDUFS4 NDUFS2
2	leigh syndrome with leukodystrophy	9.6	NDUFS4 NDUFS2
3	leukodystrophy	9.6	NDUFS4 NDUFS2
4	mitochondrial disorders	9.5	NDUFS4 NDUFS2
5	leber optic atrophy	9.5	NDUFS4 NDUFS2
6	mitochondrial complex i deficiency, nuclear type 1	9.5	NDUFS4 NDUFS2
7	mitochondrial metabolism disease	9.4	NDUFS4 NDUFS2
8	liver disease	9.2	NDUFS4 NDUFS2

Graphical network of the top 20 diseases related to Spinal Cord Dermoid Cyst:

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Symptoms & Phenotypes for Spinal Cord Dermoid Cyst

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Drugs & Therapeutics for Spinal Cord Dermoid Cyst

Search Clinical Trials , NIH Clinical Center for Spinal Cord Dermoid Cyst

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Genetic Tests for Spinal Cord Dermoid Cyst

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Anatomical Context for Spinal Cord Dermoid Cyst

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Cord Dermoid Cyst:

¹⁹

Spinal Cord

MalaCards organs/tissues related to Spinal Cord Dermoid Cyst:

⁴⁰

Spinal Cord

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Publications for Spinal Cord Dermoid Cyst

Articles related to Spinal Cord Dermoid Cyst:

#	Title	Authors	PMID	Year
1	Spectrum of Complications in a Case of Intramedullary Dermoid. ⁶¹	Kumar S...Dhurvey D	31917306	2020

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Genes for Spinal Cord Dermoid Cyst

Genes related to Spinal Cord Dermoid Cyst (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	NDUFS2	NADH:Ubiquinone Oxidoreductase Core Subunit S2	Protein Coding	6.06	DISEASES inferred ¹⁵
2	NDUFS4	NADH:Ubiquinone Oxidoreductase Subunit S4	Protein Coding	5.6	DISEASES inferred ¹⁵

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Variations for Spinal Cord Dermoid Cyst

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Expression for Spinal Cord Dermoid Cyst

Search GEO for disease gene expression data for Spinal Cord Dermoid Cyst.

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Pathways for Spinal Cord Dermoid Cyst

Pathways related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Parkinson disease ³⁶ Show member pathways Alzheimer disease ³⁶ Huntington disease ³⁶	12.12	NDUFS4 NDUFS2
2	GABAergic synapse ³⁶ Show member pathways Morphine addiction ³⁶ Retrograde endocannabinoid signaling ³⁶	11.47	NDUFS4 NDUFS2
3	Metformin Pathway, Pharmacodynamics ⁶⁰	10.18	NDUFS4 NDUFS2

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GO Terms for Spinal Cord Dermoid Cyst

Cellular components related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	mitochondrial inner membrane	GO:0005743	9.16	NDUFS4 NDUFS2
2	respiratory chain	GO:0070469	8.96	NDUFS4 NDUFS2
3	mitochondrial respiratory chain complex I	GO:0005747	8.62	NDUFS4 NDUFS2

Biological processes related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	oxidation-reduction process	GO:0055114	9.16	NDUFS4 NDUFS2
2	mitochondrial respiratory chain complex I assembly	GO:0032981	8.96	NDUFS4 NDUFS2
3	mitochondrial electron transport, NADH to ubiquinone	GO:0006120	8.62	NDUFS4 NDUFS2

Molecular functions related to Spinal Cord Dermoid Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	NADH dehydrogenase (ubiquinone) activity	GO:0008137	8.96	NDUFS4 NDUFS2
2	oxidoreductase activity, acting on NAD(P)H	GO:0016651	8.62	NDUFS4 NDUFS2

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