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MCID: SPN041
MIFTS: 52

Spinal Cord Disease

Categories: Bone diseases, Immune diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Spinal Cord Disease

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MalaCards integrated aliases for Spinal Cord Disease:

Name: Spinal Cord Disease 12 15
Spinal Cord Diseases 55 43 44 73
Myelopathy 12 29 15
Bone Marrow Diseases 73

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases Bone diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:319
ICD9CM 35 336.9
MeSH 44 D013118
NCIt 50 C97110
SNOMED-CT 68 48522003 95648003
Sources

Summaries for Spinal Cord Disease

About this section
MedlinePlus : 43 Your spinal cord is a bundle of nerves that runs down the middle of your back. It carries signals back and forth between your body and your brain. It is protected by your vertebrae, which are the bone disks that make up your spine. If you have an accident that damages the vertebrae or other parts of the spine, this can also injure the spinal cord. Other spinal cord problems include Tumors Infections such as meningitis and polio Inflammatory diseases Autoimmune diseases Degenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy Symptoms vary but might include pain, numbness, loss of sensation and muscle weakness. These symptoms can occur around the spinal cord, and also in other areas such as your arms and legs. Treatments often include medicines and surgery.

MalaCards based summary : Spinal Cord Disease, also known as spinal cord diseases, is related to myelitis and central nervous system disease, and has symptoms including seizures, tremor and myoclonus. An important gene associated with Spinal Cord Disease is AQP4 (Aquaporin 4), and among its related pathways/superpathways are TNF signaling pathway and Dendritic Cells Developmental Lineage Pathway. The drugs Propofol and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and brain, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : 76 The spinal cord is a long, thin, tubular structure made up of nervous tissue, that extends from the... more...

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Related Diseases for Spinal Cord Disease

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Diseases related to Spinal Cord Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 435)
# Related Disease Score Top Affiliating Genes
1 myelitis 31.3 AQP4 IL6 MBP MOG TNF
2 central nervous system disease 31.3 AQP4 IFNB1 IL6 MBP MOG TNF
3 transverse myelitis 30.1 AQP4 IL6 MBP TNF
4 acute transverse myelitis 30.0 AQP4 IL6
5 peripheral nervous system disease 29.9 AQP4 IL6 MBP MOG TNF
6 spinal cord injury 29.8 AQP4 GDNF IL6 TNF
7 neuromyelitis optica 29.7 AQP4 IL6 MBP MOG
8 optic neuritis 29.7 AQP4 MBP MOG TNF
9 neuritis 29.7 AQP4 MBP MOG TNF
10 primary progressive multiple sclerosis 29.6 IFNB1 MBP MOG TNF
11 acute disseminated encephalomyelitis 29.6 AQP4 MBP MOG
12 viral infectious disease 29.6 ERVW-1 IFNB1 IL6 TNF
13 traumatic brain injury 29.5 AQP4 IL6 MBP
14 demyelinating disease 29.5 AQP4 IFNB1 MBP MOG TNF
15 internuclear ophthalmoplegia 29.5 AQP4 IFNB1 MBP MOG
16 encephalitis 29.5 AQP4 ERVW-1 MOG
17 multiple sclerosis 29.4 AQP4 ERVW-1 IFNB1 IL6 MBP MOG
18 optic nerve disease 29.4 AQP4 BTD DPYSL5 IFNB1 MBP MOG
19 human immunodeficiency virus type 1 29.1 ERVW-1 GDNF IL6 TNF
20 myelopathy, htlv-1-associated 12.6
21 vascular myelopathy 12.5
22 htlv-1 associated myelopathy/tropical spastic paraparesis 12.4
23 syphilitic myelopathy 12.4
24 retrovirus-associated myelopathy 12.3
25 tropical spastic paraparesis 12.0
26 spondylosis 11.7
27 ossification of the posterior longitudinal ligament of spine 11.6
28 human t-cell leukemia virus type 1 11.5
29 foix-alajouanine syndrome 11.4
30 tabes dorsalis 11.3
31 neuroschistosomiasis 11.3
32 tethered spinal cord syndrome 11.2
33 sneddon syndrome 11.0
34 spastic paraparesis 10.8
35 radiculopathy 10.4
36 t-cell leukemia 10.4
37 leukemia 10.4
38 allergic encephalomyelitis 10.2 MBP MOG
39 adult t-cell leukemia 10.2
40 inappropriate adh syndrome 10.2 AQP4 AVPR2
41 alexia 10.2 AQP4 MBP
42 central pontine myelinolysis 10.2 AQP4 MBP
43 cranial nerve disease 10.2 AQP4 MBP MOG
44 marburg hemorrhagic fever 10.2 IFNB1 TNF
45 leukomalacia 10.2 IL6 TNF
46 cerebral palsy 10.2
47 syringomyelia 10.2
48 scorpion envenomation 10.1 IL6 TNF
49 angioimmunoblastic lymphadenopathy with dysproteinemia 10.1 IL6 TNF
50 critical limb ischemia 10.1 IL6 TNF

Comorbidity relations with Spinal Cord Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Decubitus Ulcer
Deficiency Anemia Hypertension, Essential
Osteoporosis Paraplegia
Prostate Cancer Spinal Stenosis

Graphical network of the top 20 diseases related to Spinal Cord Disease:



Diseases related to Spinal Cord Disease
Sources

Symptoms & Phenotypes for Spinal Cord Disease

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UMLS symptoms related to Spinal Cord Disease:


seizures, tremor, myoclonus, back pain, pain, headache, hemiplegia, syncope, chronic pain, sciatica, vertigo/dizziness, sleeplessness, hyperexplexia

MGI Mouse Phenotypes related to Spinal Cord Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.9 ADAMTS1 AQP4 AVPR2 BTD GDNF HBZ
2 hematopoietic system MP:0005397 9.65 AQP4 AVPR2 GDNF GNB1L HBZ IFNB1
3 renal/urinary system MP:0005367 9.17 ADAMTS1 AQP4 AVPR2 BTD GDNF GNB1L
Sources

Drugs & Therapeutics for Spinal Cord Disease

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Drugs for Spinal Cord Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 618)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
3
Lidocaine Approved, Vet_approved Phase 4,Phase 2 137-58-6 3676
4
Acetylcholine Approved Phase 4,Phase 2,Phase 3,Not Applicable 51-84-3 187
5
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 148553-50-8 5486971
6 tannic acid Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
7
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
8
Riluzole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 1744-22-5 5070
9
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-61-6, 62-31-7 681
10
Citalopram Approved Phase 4,Phase 3,Phase 1,Not Applicable 59729-33-8 2771
11
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7439-89-6 23925
12
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 302-25-0
13
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 50-24-8 5755
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 83-43-2 6741
15
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1,Not Applicable 2921-57-5
16
Oxybutynin Approved, Investigational Phase 4,Phase 2,Not Applicable 5633-20-5 4634
17
Meloxicam Approved, Vet_approved Phase 4 71125-38-7 54677470 5281106
18
Darifenacin Approved, Investigational Phase 4 133099-04-4 444031
19
Neostigmine Approved, Vet_approved Phase 4,Phase 1,Early Phase 1 59-99-4 4456
20
Tadalafil Approved, Investigational Phase 4,Phase 3 171596-29-5 110635
21
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
22
Oxcarbazepine Approved Phase 4 28721-07-5 34312
23 Piracetam Approved, Investigational Phase 4,Phase 3,Phase 2 7491-74-9
24
Amitriptyline Approved Phase 4 50-48-6 2160
25
Perphenazine Approved Phase 4 58-39-9 4748
26
Zoledronic acid Approved Phase 4,Phase 3,Phase 2 118072-93-8 68740
27
Mexiletine Approved, Investigational Phase 4,Phase 2 31828-71-4 4178
28
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
29
Phenol Approved, Experimental Phase 4,Not Applicable 108-95-2 996
30
Norepinephrine Approved Phase 4,Phase 2,Not Applicable 51-41-2 439260
31
Bupropion Approved Phase 4 34841-39-9, 34911-55-2 444
32
Zinc sulfate Approved, Investigational Phase 4,Not Applicable 7733-02-0
33
Zinc Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 7440-66-6
34
Pentetic acid Approved Phase 4,Phase 3,Phase 2 67-43-6
35
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 62-33-9, 60-00-4 6049
36
Teriparatide Approved, Investigational Phase 4,Phase 2 52232-67-4 16133850
37
Goserelin Approved Phase 4 65807-02-5 47725 5311128
38
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
39
Interferon beta-1a Approved, Investigational Phase 4,Phase 2 145258-61-3 6438354
40
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 93-14-1 3516
41
Dextromethorphan Approved Phase 4,Phase 3,Phase 2 125-71-3 5360696 5362449
42
Droxidopa Approved, Investigational Phase 4,Phase 1 23651-95-8 443940
43
leucovorin Approved Phase 4,Phase 1,Phase 2 58-05-9 6006 143
44
Cycloserine Approved Phase 4 68-41-7 6234 401
45
Denosumab Approved Phase 4 615258-40-7
46
Trazodone Approved, Investigational Phase 4,Phase 2 19794-93-5 5533
47
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
48
Vancomycin Approved Phase 4 1404-90-6 14969 441141
49
Serine Approved, Nutraceutical Phase 4,Phase 1,Phase 2 56-45-1 5951
50
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59-30-3 6037

Interventional clinical trials:

(show top 50) (show all 1884)
# Name Status NCT ID Phase Drugs
1 Anesthesia Induction in Patients Undergoing Surgery for Cervical Myelopathy Unknown status NCT01052337 Phase 4 anaesthetics: sevofluorane
2 Exoskeletons for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943669 Phase 4
3 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943656 Phase 4
4 Functional Electrical Stimulation-Assisted Walking: Reduction of Secondary Complications Due to Spinal Cord Injury Unknown status NCT00201968 Phase 4
5 Botox for Neurogenic Detrusor Overactivity and the Prevention of Autonomic Dysreflexia Following SCI Unknown status NCT02298660 Phase 4 BOTOX
6 Pregabalin for the Treatment and Prevention of Spinal Cord Injury Neuropathic Pain Unknown status NCT01479556 Phase 4 Pregabalin;Placebo
7 A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury Unknown status NCT00725790 Phase 4 Vardenafil;Placebo
8 Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine Unknown status NCT01841671 Phase 4
9 Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis Unknown status NCT00560287 Phase 4
10 Clinical Study of Solifenacin Succinate in Patients With Bladder Symptoms Due to Spinal Cord Injury or Multiple Sclerosis Completed NCT00629642 Phase 4 Solifenacin Succinate;Solifenacin Succinate;Oxybutynin Hydrochloride;Placebo
11 Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level Completed NCT00554528 Phase 4
12 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
13 Comparative Study of the Efficacy and Safety of Muscarinic M3 Receptors Antagonists in the Treatment of Neurogenic Detrusor Overactivity Completed NCT00800462 Phase 4 Oxybutynin Cl;Trospium Cl;Darifenacin Hydrogen Bromide (HBr)
14 Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage Completed NCT00745095 Phase 4 Neostigmine
15 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Completed NCT03226119 Phase 4
16 Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males Completed NCT01067391 Phase 4 tadalafil;placebo
17 Symptom Based Treatment of Neuropathic Pain Completed NCT02180880 Phase 4 Pregabalin and Oxcarbazepine
18 Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels Completed NCT01896037 Phase 4
19 Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients Completed NCT01579500 Phase 4 Botulinum toxin type A;normal saline
20 Pressure Ulcer Healing With Microcyn Completed NCT02001558 Phase 4 Microcyn
21 Assess Efficacy in Subjects With Traumatic Spinal Cord Injury Completed NCT00667966 Phase 4 Vardenafil (Levitra, BAY 38-9456), 10 mg;Placebo;Vardenafil (Levitra, BAY 38-9456), 20 mg
22 A Study Evaluating the Efficacy and Safety of Sildenafil in Men With Traumatic Spinal Cord Injury and Erectile Dysfunction Completed NCT00654082 Phase 4 sildenafil;placebo
23 Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia Completed NCT00507546 Phase 4 Ramelteon;Placebo
24 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
25 Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury Completed NCT00286520 Phase 4
26 Levetiracetam in Chronic Neuropathic Pain Following Spinal Cord Injury Completed NCT00252954 Phase 4 Levetiracetam
27 Chronic Pain in Spinal Cord Injury Completed NCT00006428 Phase 4 Amitriptyline
28 Zoledronic Acid Administration in Acute Spinal Cord Injury Completed NCT02042872 Phase 4 Zoledronic acid
29 Fractional Inactivated Poliovirus Vaccine Booster and Rotavirus Study Completed NCT02847026 Phase 4
30 Mexiletine for the Treatment of Muscle Cramps in ALS Completed NCT01811355 Phase 4 Mexiletine;Placebo
31 Immunogenicity of Monovalent Type 2 Oral Poliovirus Vaccine Completed NCT02643368 Phase 4
32 A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania Completed NCT02582255 Phase 4
33 A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age Completed NCT02580201 Phase 4
34 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrixâ„¢ During Pregnancy or Immediately Post-delivery Completed NCT02422264 Phase 4 Prevnar13
35 Intestinal and Humoral Immunity of Sequential Polio Vaccination Schedules Completed NCT02412514 Phase 4
36 Myobloc Atrophy Study Completed NCT02052024 Phase 4 Botox;MYOBLOC
37 Polio End-game Strategies - Poliovirus Type 2 Challenge Study Completed NCT02189811 Phase 4
38 Study of IMOVAX POLIO® Subcutaneous as a Booster Vaccine in Pre-school Age Children in Japan Completed NCT02005536 Phase 4
39 Feasibility of Telesurveillance and Home Cough Assistance for Amyotrophic Lateral Patients (ALS) Completed NCT00613899 Phase 4
40 Project to Improve Symptoms and Mood in People With Spinal Cord Injury Completed NCT00592384 Phase 4 venlafaxine XR;placebo
41 IPV Clinical Trial - The Gambia Completed NCT01847872 Phase 4 IPV IM Needle;IPV ID Needle;IPV IM Device;IPV ID Device
42 Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine Completed NCT01831050 Phase 4
43 CARE Canadian ALS Riluzole Evaluation Completed NCT00542412 Phase 4 Riluzole
44 An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich Ataxia Completed NCT01716221 Phase 4 bupropion & Citalopram;Bupropion & Placebo;Placebo & Citalopram;Placebo & Placebo
45 IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi. Completed NCT01695798 Phase 4
46 Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines Completed NCT01616693 Phase 4
47 Antibody Persistence to REVAXIS or DT Polio and Immune Response to TETRAVAC-ACELLULAIRE Completed NCT01546909 Phase 4
48 Sequential Inactivated Poliomyelitis Vaccine Followed by Oral Poliomyelitis Vaccine Versus Oral Poliomyelitis Vaccine Completed NCT01475539 Phase 4
49 Comparison of Immunogenicity and Reactogenicity of INFANRIXâ„¢ HEXA and HEXAVACâ„¢ Vaccines as a Primary Vaccination Course Completed NCT01457547 Phase 4
50 Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI) Completed NCT00826228 Phase 4 teriparatide

Search NIH Clinical Center for Spinal Cord Disease

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: spinal cord diseases

Sources

Genetic Tests for Spinal Cord Disease

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Genetic tests related to Spinal Cord Disease:

# Genetic test Affiliating Genes
1 Myelopathy 29
Sources

Anatomical Context for Spinal Cord Disease

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MalaCards organs/tissues related to Spinal Cord Disease:

41
Spinal Cord, Bone, Brain, Bone Marrow, Medulla Oblongata, T Cells, Cortex
Sources

Publications for Spinal Cord Disease

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Articles related to Spinal Cord Disease:

(show top 50) (show all 100)
# Title Authors Year
1
Agreement between transverse T2-weighted and three-dimensional constructive interference in steady state sequences in the evaluation of spinal cord disease in dogs. ( 29540556 )
2018
2
HIV and spinal cord disease. ( 29604979 )
2018
3
Application of fiber tractography and diffusion tensor imaging to evaluate spinal cord diseases in dogs. ( 28025450 )
2017
4
Evaluation of magnetic resonance imaging for the differentiation of inflammatory, neoplastic, and vascular intradural spinal cord diseases in the dog. ( 28421647 )
2017
5
Primary central nervous system lymphoma of T-cell origin: an unusual cause of spinal cord disease. ( 27878765 )
2016
6
Prevalence, clinical presentation, prognosis, and outcome of 17 dogs with spinal shock and acute thoracolumbar spinal cord disease. ( 26676985 )
2016
7
The intrinsic pathogenic role of autoantibodies to aquaporin 4 mediating spinal cord disease in a rat passive-transfer model. ( 25542977 )
2015
8
[Novel aspects of diagnostics and therapy of spinal cord diseases]. ( 25001239 )
2014
9
Autonomic rectal dysfunction in patients with multiple sclerosis and bowel symptoms is secondary to spinal cord disease. ( 24608309 )
2014
10
Sacral neuromodulation for neurogenic bladder and bowel dysfunction with multiple symptoms secondary to spinal cord disease. ( 25224602 )
2014
11
Depression and pain among inpatients with spinal cord injury and spinal cord disease: differences in symptoms and neurological function. ( 23072715 )
2013
12
STIR muscle hyperintensity in the cervical muscles associated with inflammatory spinal cord disease of unknown origin. ( 23458643 )
2013
13
Positron emission tomography in spinal cord disease. ( 24182699 )
2013
14
Low serum vitamin D levels and recurrent inflammatory spinal cord disease. ( 22083799 )
2012
15
Spinal cord disease in patients with cancer. ( 22810129 )
2012
16
Stress, internal resources and functioning in a person with spinal cord disease. ( 22430577 )
2012
17
Anorectal function and the effect of biofeedback therapy in ambulatory spinal cord disease patients having constipation. ( 20602567 )
2010
18
Feline spinal cord diseases. ( 20732602 )
2010
19
Clinical and magnetic resonance imaging findings in 92 cats with clinical signs of spinal cord disease. ( 18602328 )
2009
20
Surgical management of pressure ulcers during inpatient neurologic rehabilitation: outcomes for patients with spinal cord disease. ( 19569459 )
2009
21
Characterization of spatiotemporal gait characteristics in clinically normal dogs and dogs with spinal cord disease. ( 19951114 )
2009
22
The paralyzed cat. Neuroanatomic diagnosis and specific spinal cord diseases. ( 19389636 )
2009
23
Profound biotinidase deficiency in a child with predominantly spinal cord disease. ( 18645204 )
2008
24
Rehabilitation outcomes after infection-related spinal cord disease: a retrospective analysis. ( 18356619 )
2008
25
Signs of spinal cord disease in two heifers caused by Listeria monocytogenes. ( 14758832 )
2004
26
Spinal cord disease in West Nile virus infection. ( 12575663 )
2003
27
From the electrodiagnosis lab...H-reflexes in hand muscles after cervical spinal cord disease. ( 14598812 )
2003
28
Spinal cord disease in West Nile virus infection. ( 12571269 )
2003
29
[An autopsy case with subacute spinal cord disease showing progressive paraplegia]. ( 12166108 )
2002
30
Botulinum a toxin and detrusor sphincter dyssynergia: a double-blind lidocaine-controlled study in 13 patients with spinal cord disease. ( 12121731 )
2002
31
Electrophysiological evaluation of root and spinal cord disease. ( 12524565 )
2002
32
The use of magnetic motor evoked potentials in horses with cervical spinal cord disease. ( 11902758 )
2002
33
Correlation between severity of clinical signs and motor evoked potentials after transcranial magnetic stimulation in large-breed dogs with cervical spinal cord disease. ( 12420825 )
2002
34
Dysfunctional elimination syndrome in children without obvious spinal cord diseases. ( 11732126 )
2001
35
Intrathecal baclofen therapy for spinal origin spasticity: spinal cord injury, spinal cord disease, and multiple sclerosis. ( 22151114 )
1999
36
Spinal cord disease due to melioidosis. ( 10450444 )
1999
37
Spinal cord diseases-diagnosis and treatment ( 10369844 )
1999
38
Botulinum A toxin treatment for detrusor-sphincter dyssynergia in spinal cord disease. ( 9494997 )
1998
39
The effects of capsaicin on the neurogenic hyperreflexic detrusor. A double blind placebo controlled study in patients with spinal cord disease. Preliminary results. ( 9494998 )
1998
40
Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord diseases. ( 9825395 )
1998
41
Vertebrospinal angiography in the evaluation of vertebral and spinal cord disease. ( 8873094 )
1996
42
Chemosensitive epidural spinal cord disease in non-Hodgkins lymphoma. ( 8649545 )
1996
43
MR imaging in the diagnosis of intramedullary spinal cord diseases that involve specific neural pathways or vascular territories. ( 7645462 )
1995
44
Non-traumatic spinal cord diseases in Ibadan, Nigeria: aetiology and prognostic factors. ( 7788667 )
1995
45
Spinal cord disease due to vacuolar myelopathy in AIDS. ( 8039791 )
1994
46
[Ophthalmologic manifestations in spinal cord diseases caused by HTLV-I virus. Clinical study of 30 cases]. ( 8083490 )
1994
47
Spontaneous ejaculation secondary to spinal cord disease. ( 8164008 )
1994
48
Somatosensory potentials in dogs with naturally acquired thoracolumbar spinal cord disease. ( 8291776 )
1993
49
The diagnostic impact of magnetic resonance imaging on the evaluation of suspected spinal cord disease. ( 1441553 )
1992
50
Management of bowel dysfunction in children with spinal cord disease or injury by means of the enema continence catheter. ( 1735813 )
1992
Sources

Variations for Spinal Cord Disease

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Sources

Expression for Spinal Cord Disease

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Search GEO for disease gene expression data for Spinal Cord Disease.
Sources

Pathways for Spinal Cord Disease

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Pathways related to Spinal Cord Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
TNF signaling pathway 37
11.47 IFNB1 IL6 TNF
2
Dendritic Cells Developmental Lineage Pathway 65
11.2 IFNB1 IL6 TNF
3
Spinal Cord Injury 1
11.1 AQP4 GDNF IL6 MBP TNF
4
Cytokines and Inflammatory Response 1
10.59 IFNB1 IL6 TNF
Sources

GO Terms for Spinal Cord Disease

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Biological processes related to Spinal Cord Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of glial cell proliferation GO:0060252 9.26 IL6 TNF
2 negative regulation of lipid storage GO:0010888 9.16 IL6 TNF
3 humoral immune response GO:0006959 9.13 IFNB1 IL6 TNF
4 positive regulation of neuroinflammatory response GO:0150078 8.62 IL6 TNF
Sources

Sources for Spinal Cord Disease

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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