Spinal Cord Ependymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: SPN042 MIFTS: 30	Spinal Cord Ependymoma Categories: Cancer diseases, Neuronal diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

Sources

Aliases & Classifications for Spinal Cord Ependymoma

MalaCards integrated aliases for Spinal Cord Ependymoma:

Name: Spinal Cord Ependymoma ¹² ⁵⁵ ¹⁵

Ependymal Neoplasm of the Spinal Cord ¹²

Ependymoma of Spinal Cord ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5503

NCIt ⁵⁰ C3875

UMLS ⁷³ C0238432

Sources

Summaries for Spinal Cord Ependymoma

Disease Ontology : ¹² A spinal cord glioma that has material basis in cells linking the spinal cord central canal.

MalaCards based summary : Spinal Cord Ependymoma, also known as ependymal neoplasm of the spinal cord, is related to benign ependymoma and adult spinal cord ependymoma. An important gene associated with Spinal Cord Ependymoma is NF2 (Neurofibromin 2), and among its related pathways/superpathways is Protein-protein interactions at synapses. The drugs Dacarbazine and Temozolomide have been mentioned in the context of this disorder. Affiliated tissues include spinal cord.

Sources

Related Diseases for Spinal Cord Ependymoma

Diseases in the Spinal Cord Ependymoma family:

Adult Spinal Cord Ependymoma

Diseases related to Spinal Cord Ependymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)

#	Related Disease	Score	Top Affiliating Genes
1	benign ependymoma	30.4	EPB41L3 NF2
2	adult spinal cord ependymoma	12.4
3	multiple endocrine neoplasia, type i	11.2
4	ependymoma	10.8
5	multiple sclerosis	10.1
6	spinal cancer	10.0	HOXB13 NF2
7	neurofibromatosis, type iv, of riccardi	10.0
8	hydrocephalus	10.0
9	cervical dystonia	10.0
10	neurogenic bladder	10.0
11	astrocytoma	10.0
12	syringomyelia	10.0
13	myxopapillary ependymoma	10.0
14	dystonia	10.0
15	paraplegia	10.0
16	malignant ependymoma	10.0	EPB41 NF2
17	spinal cord glioma	9.9	HOXB13 RBM10
18	benign meningioma	9.8	EPB41L3 NF2
19	meningioma, radiation-induced	9.8	EPB41L3 NF2
20	neurofibromatosis, type ii	9.7	EPB41L3 NF2
21	meningioma, familial	9.7	EPB41 EPB41L3 NF2

Graphical network of the top 20 diseases related to Spinal Cord Ependymoma:

Sources

Symptoms & Phenotypes for Spinal Cord Ependymoma

Sources

Drugs & Therapeutics for Spinal Cord Ependymoma

Drugs for Spinal Cord Ependymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Dacarbazine

Approved, Investigational

Phase 2

4342-03-4

5351166

Synonyms:

(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide

(5Z)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide

(Dimethyltriazeno)imidazolecarboxamide

37626-23-6

4-(3,3-dimethyl-1-triazeno)imidazole-5-carboxamide

4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide

4-(3,3-Dimethyltriazeno)imidazole-5-carboxamide

4(5)-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide

4-(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide

4(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide

4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide

4-(Dimethyltriazeno)imidazole-5-c arboxamide

4-(dimethyltriazeno)imidazole-5-carboxamide

4-(dimethyltriazeno)Imidazole-5-carboxamide

4-(Dimethyltriazeno)imidazole-5-carboxamide

4-(or 5)-(3,3-Dimethyl-1-triazeno)imidazole-5(or 4)-carboxamide

4-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide

4-[3,3-dimethyltriaz-1-en-1-yl]-1H-imidazole-5-carboxamide

4342-03-4

5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide

5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide

5-(3,3-Dimethyl-1-triazenyl)-1H-imidazole-4-carboxamide

5-(3,3-Dimethyl-1-triazenyl)imidazole-4-carboxamide

5-(3,3-Dimethyltri azeno)imidazole-4-carboxamide

5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide

5-(3,3-Dimethyltriazeno)-imidazole-4-carbamide

5-(3,3-dimethyltriazeno)imidazole-4-carboxamide

5-(3,3-dimethyltriazeno)Imidazole-4-carboxamide

5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide

5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide

5-(Dimethyltriazeno)-4-imidazolecarboxamide

5-(dimethyltriazeno)imidazole-4-carboxamide

5-(dimethyltriazeno)Imidazole-4-carboxamide

5-(Dimethyltriazeno)imidazole-4-carboxamide

5-(Dimethyltriazeno)imidazole-4-carboximide

5(or 4)-(dimethyltriazeno)imidazol e-4(or 5)-carboxamide

5(or 4)-(dimethyltriazeno)imidazole-4(or 5)-carboxamide

5-[3,3-Dimethyl-1-triazenyl]imidazole-4-carboxamide

94361-71-4

AC1NQXVV

AC1NS01W

AC1NS4BN

AI3-52825

Biocarbazin

Biocarbazine

Biocarbazine R

BPBio1_000428

BRD-K35520305-001-07-8

BSPBio_000388

BSPBio_002091

C6H10N6O

Carboxamide, Dimethyl Imidazole

CAS-891986

CCRIS 190

CHEBI:4305

CHEMBL476

CID5281007

CID5351166

CID5353562

D00288

D003606

D2390_SIGMA

D3634

Dacarbazin

Dacarbazina

dacarbazine

Dacarbazine

Dacarbazine (JAN/USP/INN)

Dacarbazine [USAN:INN:BAN:JAN]

Dacarbazino

Dacarbazino [INN-Spanish]

Dacarbazinum

Dacarbazinum [INN-Latin]

Dacatic

DB00851

Decarbazine

Deticene

DIC

Dimethyl Imidazole Carboxamide

Dimethyl Triazeno Imidazole Carboxamide

Dimethyltriazenoimidazolecarboxamide

Di-methyl-triazenoimidazolecarboxamide

Di-me-triazenoimidazolecarboxamide

DivK1c_000326

DTCI

DTIC

DTIC Dome

DTIC, DTIC-Dome, Dacarbazine

Dtic-dome

Dtic-Dome

DTICDome

DTIC-Dome

Dtic-Dome (TN)

DTIE

EINECS 224-396-1

HE1150000

HMS1569D10

HMS2090A20

HMS2091I20

HMS501A08

HSDB 3219

I06-2280

I14-1659

ICDMT

ICDT

IDI1_000326

Imidazole carboxamide

Imidazole Carboxamide

Imidazole Carboxamide, Dimethyl

KBio1_000326

KBio2_001364

KBio2_003932

KBio2_006500

KBio3_001311

KBioGR_000896

KBioSS_001364

LS-119

MLS001332543

MLS001332544

MolPort-003-666-153

MolPort-003-846-120

MolPort-006-709-420

NCGC00016986-01

NCGC00091861-01

NCGC00091861-02

NCGC00091861-03

NCGC00091861-04

NCI60_004053

NCI-C04717

NCIMech_000261

NINDS_000326

NIOSH/HE1150000

NPFAPI-05

NSC 45388

NSC45388

NSC-45388

Prestwick_904

Prestwick0_000574

Prestwick1_000574

Prestwick2_000574

Prestwick3_000574

S1221_Selleck

SMP2_000251

SMR000857131

SPBio_001075

SPBio_002607

Spectrum_000884

SPECTRUM1500218

Spectrum2_001148

Spectrum3_000366

Spectrum4_000308

Spectrum5_000823

ST51014976

UNII-7GR28W0FJI

WLN: T5M CNJ DVZ ENUNN1&1

Temozolomide

Approved, Investigational

Phase 2

85622-93-1

5394

Synonyms:

3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide

3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-1,2,3,5-tetrazine-8-carboxamide

3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide

3,4-dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide

3,4-dihydro-3-Methyl-4-oxoimidazo(5,1-D)-as-tetrazine-8-carboxamide

3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide

3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide

3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide

3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-D)(1,2,3,5)tetrazine-8-carboxamide

3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide

3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

85622-93-1

8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one

8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one

8-Carbamoyl-3-methylimidazo(5,1-D)-1,2,3,5-tetrazin-4(3H)-one

AC1L1K9B

AC-758

BIDD:GT0204

Bio-0147

BRN 5547136

C047246

C6H6N6O2

CCRG 81045

CCRG-81045

CCRIS 8996

CHEBI:153686

CHEMBL810

CID5394

CPD000466338

D06067

DB00853

Essex brand of temozolomide

HMS2051O12

HMS2090B08

I06-0149

I14-1943

LS-80558

M B 39831

m & b 39831

M & B 39831

m And b 39831

m And b-39831

M&B 39831

M&B-39831

M-39831

MB 39831

Methazolastone

MLS000759447

MLS001424028

MLS002701861

NCGC00167429-01

NCGC00167429-02

NCI60_003316

NSC 362856

NSC362856

NSC-362856

SAM001246636

Sch 52365

SCH 52365

Sch-52365

Schering brand of temozolomide

Schering-Plough brand of temozolomide

SMR000466338

STK623541

Temodal

Temodal (TN)

Temodar

Temozolamide

Temozolodida

Temozolodida [Spanish]

Temozolomid

Temozolomida

temozolomide

Témozolomide

Temozolomide (JAN/USAN/INN)

Temozolomide [INN:BAN]

Temozolomidum

Temozolomidum [Latin]

TL8005593

TMZ

TMZ-Bioshuttle

UNII-YF1K15M17Y

ZINC01482184

Bevacizumab

Approved, Investigational

Phase 2

216974-75-3

Synonyms:

216974-75-3

antiVEGF

anti-VEGF monoclonal antibody

Avastin

Avastin (TN)

bevacizumab

Bevacizumab

Bevacizumab (genetical recombination)

Bevacizumab (genetical recombination) (JAN)

bevacizumab-awwb

D06409

R-435

Carboplatin

Approved

Phase 2

41575-94-4

10339178 38904 498142

Synonyms:

(SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum

/h1-3H2,(H,7,8)(H,9,10)

1,1-Cyclobutanedicarboxylate diammine platinum (II)

1,1-Cyclobutanedicarboxylate diammine platinum(II)

2*-1

2*1H2

41575-94-4

70903-55-8

AC-1457

AC1L8I6U

Ambap41575-94-4

azanide

Blastocarb

BSPBio_003145

C 2538

C2043

C2538_SIGMA

C6H10N2O4Pt

Carbopaltin

Carboplat

carboplatin

Carboplatin

Carboplatin (JAN/USP/INN)

Carboplatin (USAN)

Carboplatin [USAN:INN:BAN:JAN]

Carboplatine

Carboplatine [French]

Carboplatino

Carboplatino [Spanish]

Carboplatinum

Carboplatinum [Latin]

Carbosin

Carbotec

Cbdca

CBDCA

CCRIS 3404

CHEBI:31355

CHEMBL1351

CHEMBL288376

CID10339178

CID2567

CID38904

CID426756

CID498142

CID5352133

CID6398587

CID6603770

cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum

cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(ii)

cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II)

cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)

cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II)

cis-Diammine(1,1-cyclobutanedicarboxylato) platinum

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum

cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)

cis-Diammine(cyclobutanedicarboxylato)platinum II

Cyclobutane-1,1-dicarboxylate

cyclobutane-1,1-dicarboxylic acid

D01363

DB00958

Diammine(1,1-cyclobutanedicarboxylato)platinum (II)

Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum

diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum

Diammine-1,1-cyclobutane dicarboxylate platinum II

DivK1c_000892

EINECS 255-446-0

Ercar

EU-0100230

HMS1921J16

HMS2090M05

HMS2092B22

HMS502M14

HSDB 6957

I14-2390

IDI1_000892

InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6

IUPAC: Azane

JM 8

JM8

JM-8

KBio1_000892

KBio2_002009

KBio2_004577

KBio2_007145

KBio3_002645

KBioGR_000713

KBioSS_002009

Lopac0_000230

Lopac-C-2538

LS-117689

MolPort-003-665-501

MolPort-003-845-609

NCGC00015223-01

NCGC00093695-01

NCGC00094961-01

NCGC00094961-02

NCGC00094961-03

NCGC00162099-01

NCGC00162099-02

NCGC00167800-01

NCGC00178242-01

nchembio.573-comp10

nchembio773-comp2

nchembio873-comp3

Nealorin

Neocarbo

NINDS_000892

NSC 201345

NSC 241240

NSC201345

NSC241240

NSC-241240

Paraplatin

Paraplatin (TN)

Paraplatin, Carboplatin

Paraplatin-AQ

Platinum(+2) Cation

platinum(2+)

Platinum(II), (1, 1-cyclobutanedicar

Platinum, {diammine[1,1-cyclobut

Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2)

Ribocarbo

S1215_Selleck

SPBio_000716

Spectrum_001529

SPECTRUM1502106

Spectrum2_000898

Spectrum3_001503

Spectrum4_000337

Spectrum5_001094

UNII-BG3F62OND5

Lapatinib

Approved March 2007, Investigational

Phase 2

388082-78-8, 231277-92-2

208908 9941095

Synonyms:

1xkk

231277-92-2

388082-78-8

4-[[3-Chloro-4-(3-fluorobenzyloxy)phenyl]amino]-6-[5-[[(2-methanesulfonylethyl)amino]methyl]furan-2-yl]quinazoline

AB1004631

AC-1314

AC1L4LL4

AKOS005145766

CHEBI:49603

CHEMBL1201179

CHEMBL554

CID11557040

CID208908

D04024

D08108

DB01259

DB02584

EN002712

FMM

GSK 572016

GSK572016

GW 572016

GW 572016X

GW2016

GW-2016

GW572016

GW-572016

GW-572016F

HMS2089H10

I01-1247

Kinome_3684

Kinome_3685

lapatinib

Lapatinib

Lapatinib (INN)

Lapatinib [INN]

lapatinib ditosylate

Lapatinib ditosylate

Lapatinib Ditosylate

Lapatinib ditosylate (USAN)

LAPATINIB DITOSYLATE MONOHYDRATE

Lapatinib tosilate hydrate

Lapatinib tosilate hydrate (JAN)

Lapatinib, Tykerb, GW572016

LS-187029

LS-187771

N-(3-chloro-4-(((3-Fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine

N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine

N-(3-chloro-4-((3-Fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulphonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine

N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-((2-methylsulfonylethylamino)methyl)-2-furyl)quinazolin-4-amine

N-(3-Chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine

N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine

N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE

N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine

NCGC00167507-01

nchembio866-comp20

NSC745750

TL80090051

Tycerb

Tykerb

Tykerb (TN)

Tyverb

UNII-0VUA21238F

Antineoplastic Agents, Alkylating

Phase 2

Protein Kinase Inhibitors

Phase 2

Alkylating Agents

Phase 2

Angiogenesis Inhibitors

Phase 2

Angiogenesis Modulating Agents

Phase 2

Proteasome Inhibitors

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma	Completed	NCT00826241	Phase 2	Temozolomide;Lapatinib
2	Carboplatin and Bevacizumab for Recurrent Ependymoma	Recruiting	NCT01295944	Phase 2	Carboplatin;Bevacizumab
3	Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma	Not yet recruiting	NCT03727841	Phase 2	Marizomib

Search NIH Clinical Center for Spinal Cord Ependymoma

Sources

Genetic Tests for Spinal Cord Ependymoma

Sources

Anatomical Context for Spinal Cord Ependymoma

MalaCards organs/tissues related to Spinal Cord Ependymoma:

⁴¹

Spinal Cord

Sources

Publications for Spinal Cord Ependymoma

Articles related to Spinal Cord Ependymoma:

(show all 47)

#	Title	Authors	Year
1	Intramedullary spinal cord ependymoma and astrocytoma: intraoperative frozen-section diagnosis, extent of resection, and outcomes. ( 30485241 )		2018
2	Is NF2 a Key Player of the Differentially Expressed Gene Between Spinal Cord Ependymoma and Intracranial Ependymoma? ( 30031196 )	Kim KT...Kim JH	2018
3	Clinical outcomes of radiotherapy for spinal cord ependymoma with adverse prognostic features: a single-center study. ( 30203166 )	Byun HK...Suh CO	2018
4	Variety of preoperative MRI changes in spinal cord ependymoma of WHO grade II: a case series. ( 30209583 )	Kobayashi K...Imagama S	2018
5	Natural history of intramedullary spinal cord ependymoma in patients preferring nonoperative treatment. ( 28667596 )	Behmanesh B....Marquardt G.	2017
6	Regional Spinal Cord Atrophy Is Associated with Poor Outcome After Surgery on Intramedullary Spinal Cord Ependymoma: A New Aspect of Delayed Neurological Deterioration. ( 28104525 )	Behmanesh B....Marquardt G.	2017
7	LncRNA LINC00880 promotes cell proliferation, migration and invasion while inhibiting apoptosis by targeting CACNG5 through the MAPK signaling pathway in spinal cord ependymoma. ( 29215699 )		2017
8	Spinal cord ependymoma: a review of the literature and case series of ten patients. ( 27154165 )	Celano E...Hadjipanayis CG	2016
9	Spinal cord ependymoma presenting with neurological deficits in the setting of trauma. ( 24982562 )	Saad A.F....Opatowsky M.J.	2014
10	Spinal cord ependymoma associated with neurofibromatosis 1 : case report and review of the literature. ( 24570818 )		2014
11	Microsurgical resection of intramedullary spinal cord ependymoma. ( 25175587 )		2014
12	Spinal cord ependymoma in children--results of postoperative radiotherapy. ( 23490267 )	PA9dziwiatr K....Chojnacka M.	2013
13	Cytologic diagnosis of spinal cord ependymoma in cerebrospinal fluid. ( 23547427 )	Kalogeraki A....Stathopoulos E.N.	2012
14	Multiple sclerosis coexisting with spinal cord ependymoma: a case report. ( 23126220 )	Degirmenci E.	2012
15	Giant spinal cord ependymoma with CSF spread. ( 23008221 )		2012
16	Laser-assisted microsurgical resection of thoracic intramedullary spinal cord ependymoma. ( 26016400 )		2012
17	Clinical analysis of 21 cases of spinal cord ependymoma : positive clinical results of gross total resection. ( 20224707 )	Kaner T....Ozer A.F.	2010
18	TENS and FES for sensory impairment and gait dysfunction following removal of spinal cord ependymoma--a case report. ( 19387998 )	Donnellan C.P....Caldwell K.	2009
19	Total removal of cervicothoracic intramedullary 160-mm-long spinal cord ependymoma: a rare case report. ( 21686716 )	Yurt A....AtA+cA+ M.	2009
20	Outcome predictors in the management of spinal cord ependymoma. ( 16865377 )	Gavin Quigley D...Jenkinson MD	2007
21	Surgical and radiotherapy treatment of a spinal cord ependymoma in a dog. ( 16498832 )	Ueno H....Uzuka Y.	2006
22	Subtle clinical signs of a spinal cord ependymoma at the cervicothoracic level in an adult: a case report. ( 17549184 )	O'Shaughnessy J...Bussi?res A	2006
23	Spinal cord ependymoma: radical surgical resection and outcome. ( 12879876 )	Vandertop W.P.	2003
24	Spinal cord ependymoma: radical surgical resection and outcome. ( 12383361 )	Hanbali F....Gokaslan Z.L.	2002
25	Etoposide for recurrent spinal cord ependymoma. ( 11971113 )	Chamberlain MC	2002
26	Spinal cord ependymoma presenting with acute paraplegia due to tumoral bleeding. ( 11105838 )	Lagares A....Boto G.R.	2000
27	Special feature: pathological case of the month. Diagnosis and discussion: neurofibromatosis 2 with bilateral vestibular schwannomas and spinal cord ependymoma. ( 10980805 )	Arnold S.R....Gilbert-Barness E.	2000
28	[Multiple sclerosis, spinal cord ependymoma and intracranial meningioma: case report]. ( 11105086 )		2000
29	Surgical outcome of intramedullary spinal cord ependymoma. ( 10352743 )	Ohata K....Hakuba A.	1999
30	Diagnosis of spinal cord ependymoma and astrocytic tumours with magnetic resonance imaging. ( 10833579 )	Koyanagi I...Miyasaka K	1999
31	Lipidized (foamy) tumor cells in a spinal cord ependymoma with collagenous metaplasia. ( 9560021 )		1998
32	Spinal cord ependymoma: a positron emission tomographic study with (11C-methyl)-L-methionine. ( 8773278 )		1996
33	Giant spinal cord ependymoma in a child. Case report. ( 8913964 )		1996
34	Cervical dystonia due to spinal cord ependymoma: involvement of cervical cord segments in the pathogenesis of dystonia. ( 7565833 )	Cammarota A....Lera G.	1995
35	The pathogenesis of syringomyelia in spinal cord ependymoma. ( 7889696 )	Lohle P.N....Go K.G.	1994
36	Papilloedema and hydrocephalus in spinal cord ependymoma. ( 8199121 )	Kesler A....Manor R.S.	1994
37	Intramedullary abscess associated with a spinal cord ependymoma: case report. ( 1738441 )	Babu R...Ransohoff J	1992
38	Postoperative radiotherapy in the management of spinal cord ependymoma. ( 2013772 )	Whitaker S.J....Brada M.	1991
39	Spinal cord ependymoma in two young dogs. ( 3051647 )	de Vries-Chalmers Hoynk van Papendrecht H.R....van Nes J.J.	1988
40	A case of malignant spinal cord ependymoma in association with a duplication of part of the long arm of chromosome 12. ( 3989836 )		1985
41	Thoracic spinal cord ependymoma presenting with ejaculatory failure. Case report. ( 7054411 )	Berciano J....Dierssen G.	1982
42	Flaccid neurogenic bladder as a presenting symptom of spinal cord ependymoma. ( 513236 )		1979
43	Spinal cord ependymoma in a dog. ( 245206 )	Chaffee V.W.	1977
44	Rapid arteriovenous shunting in a spinal cord ependymoma. Case report. ( 1271096 )	YUHL E.T....Bentson J.R.	1976
45	A huge intramedullary spinal cord ependymoma with complete recovery following total excision. ( 1238917 )		1975
46	Repeated &quot;occult&quot; spinal subarachnoid hemorrhage and spinal cord ependymoma. ( 4854114 )		1974
47	Rupture of spinal cord ependymoma. Case report. ( 4743575 )	Payne N.S....McDonald J.V.	1973

Sources

Genes for Spinal Cord Ependymoma

Genes related to Spinal Cord Ependymoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	NF2	Neurofibromin 2	Protein Coding	22.68	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	8805149 11063814
2	HOXB13	Homeobox B13	Protein Coding	15.84	DISEASES inferred ¹⁵
3	RBM10	RNA Binding Motif Protein 10	Protein Coding	15.57	DISEASES inferred ¹⁵
4	EPB41L3	Erythrocyte Membrane Protein Band 4.1 Like 3	Protein Coding	15.12	DISEASES inferred ¹⁵
5	EPB41	Erythrocyte Membrane Protein Band 4.1	Protein Coding	14.78	DISEASES inferred ¹⁵

Sources

Variations for Spinal Cord Ependymoma

Sources

Expression for Spinal Cord Ependymoma

Search GEO for disease gene expression data for Spinal Cord Ependymoma.

Sources

Pathways for Spinal Cord Ependymoma

Pathways related to Spinal Cord Ependymoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Protein-protein interactions at synapses ⁶⁶ Show member pathways Interactions of neurexins and neuroligins at synapses ⁶⁶	10.74	EPB41 EPB41L3

Sources

GO Terms for Spinal Cord Ependymoma

Biological processes related to Spinal Cord Ependymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	actin cytoskeleton organization	GO:0030036	9.26	EPB41 NF2
2	regulation of cell shape	GO:0008360	9.16	EPB41 EPB41L3
3	actomyosin structure organization	GO:0031032	8.96	EPB41 EPB41L3
4	cortical actin cytoskeleton organization	GO:0030866	8.62	EPB41 EPB41L3

Molecular functions related to Spinal Cord Ependymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	structural molecule activity	GO:0005198	9.26	EPB41 EPB41L3
2	structural constituent of cytoskeleton	GO:0005200	9.16	EPB41 EPB41L3
3	actin binding	GO:0003779	9.13	EPB41 EPB41L3 NF2
4	cytoskeletal protein binding	GO:0008092	8.8	EPB41 EPB41L3 NF2

Sources

Sources for Spinal Cord Ependymoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia