MCID: SPN043
MIFTS: 26

Spinal Cord Glioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Spinal Cord Glioma

MalaCards integrated aliases for Spinal Cord Glioma:

Name: Spinal Cord Glioma 12 15
Glial Tumor of Spinal Cord 12 74
Glial Neoplasm Spinal Cord 12
Glioma of Spinal Cord 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3185
NCIt 51 C4534
UMLS 74 C2937245

Summaries for Spinal Cord Glioma

Disease Ontology : 12 A spinal cancer that is located in the spinal cord and has material basis in glial cells.

MalaCards based summary : Spinal Cord Glioma, also known as glial tumor of spinal cord, is related to spinal cord ependymoma and glioma. An important gene associated with Spinal Cord Glioma is HOXB13 (Homeobox B13). Affiliated tissues include spinal cord and brain, and related phenotypes are nervous system and respiratory system

Related Diseases for Spinal Cord Glioma

Diseases related to Spinal Cord Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 spinal cord ependymoma 31.1 HOXB13 NF2 RBM10
2 glioma 10.6
3 cerebellopontine angle tumor 9.9 IDH1 NF2
4 glioma susceptibility 1 9.9
5 pneumothorax 9.9
6 pulmonary tuberculosis 9.9
7 glioblastoma multiforme 9.9
8 rhabdomyosarcoma 9.9
9 glioblastoma 9.9
10 myoclonus 9.9
11 central nervous system cancer 9.9 IDH1 NF2
12 nervous system cancer 9.7 IDH1 NF2
13 spinal cancer 9.6 HOXB13 NF2 NRXN2

Graphical network of the top 20 diseases related to Spinal Cord Glioma:



Diseases related to Spinal Cord Glioma

Symptoms & Phenotypes for Spinal Cord Glioma

MGI Mouse Phenotypes related to Spinal Cord Glioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.35 GNB1L HOXB13 NF2 NRXN2 PTBP2
2 respiratory system MP:0005388 8.92 IDH1 NF2 NRXN2 PTBP2

Drugs & Therapeutics for Spinal Cord Glioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy Recruiting NCT03668522
2 Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently Recruiting NCT03496181

Search NIH Clinical Center for Spinal Cord Glioma

Genetic Tests for Spinal Cord Glioma

Anatomical Context for Spinal Cord Glioma

MalaCards organs/tissues related to Spinal Cord Glioma:

42
Spinal Cord, Brain

Publications for Spinal Cord Glioma

Articles related to Spinal Cord Glioma:

(show all 28)
# Title Authors Year
1
Treatment outcomes of radiotherapy for primary spinal cord glioma. ( 30203111 )
2019
2
Letter: Impact of H3.3 K27M Mutation on Prognosis and Survival of Grade IV Spinal Cord Glioma on the Basis of New 2016 World Health Organization Classification of the Central Nervous System. ( 30379319 )
2018
3
Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF-κB Signaling Pathway. ( 30071522 )
2018
4
Impact of H3.3 K27M Mutation on Prognosis and Survival of Grade IV Spinal Cord Glioma on the Basis of New 2016 World Health Organization Classification of the Central Nervous System. ( 29718432 )
2018
5
Canine spinal cord glioma. ( 28074710 )
2017
6
Convection-enhanced delivery of a hydrophilic nitrosourea ameliorates deficits and suppresses tumor growth in experimental spinal cord glioma models. ( 28247160 )
2017
7
Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. ( 26671631 )
2016
8
Letter to the Editor: High-grade spinal cord glioma. ( 26895525 )
2016
9
Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. ( 27191809 )
2016
10
A Case of Congenital Malignant Spinal Cord Glioma as a Cause of Congenital Ascites in a Neonate. ( 27597917 )
2016
11
Long-term cure of high-grade spinal cord glioma in a pediatric patient who underwent cordectomy. ( 26252785 )
2015
12
Delayed development of a rhabdomyosarcoma following radiation for a spinal cord glioma. ( 23296545 )
2013
13
Animal model of intramedullary spinal cord glioma using human glioblastoma multiforme neurospheres. ( 22195609 )
2012
14
Spinal cord glioma metastasizing to the brain. ( 22529250 )
2012
15
Temozolomide for malignant primary spinal cord glioma: an experience of six cases and a literature review. ( 20526650 )
2011
16
Primary spinal cord glioma: a Surveillance, Epidemiology, and End Results database study. ( 19898743 )
2010
17
Targeted therapy of spinal cord glioma with a genetically modified Salmonella typhimurium. ( 19922490 )
2010
18
Establishment of intramedullary spinal cord glioma model in rats. ( 21034632 )
2010
19
Paroxysmal Kinesigenic Segmental Myoclonus due to a spinal cord glioma. ( 17595044 )
2007
20
Radiation-induced spinal cord glioma subsequent to treatment of Hodgkin's disease: case report and review. ( 16158216 )
2006
21
Spinal cord glioma in a ridge-nosed rattlesnake (Crotalus willardi). ( 17323575 )
2005
22
The prognostic value of neurologic function in astrocytic spinal cord glioma. ( 12816727 )
2003
23
A retrospective analysis of 52 cases of spinal cord glioma managed with radiation therapy. ( 11020582 )
2000
24
The role of radiotherapy in the management of spinal cord glioma. ( 7673019 )
1995
25
MRI of radiation induced spinal cord glioma. ( 2234396 )
1990
26
Intramedullary spinal cord glioma with intracranial seeding. ( 3998737 )
1985
27
Spinal cord glioma following irradiation for Hodgkin's disease. ( 7370950 )
1980
28
Spinal cord glioma after multiple fluoroscopies during artificial pneumothorax treatment of pulmonary tuberculosis: case report. ( 7381543 )
1980

Variations for Spinal Cord Glioma

Expression for Spinal Cord Glioma

Search GEO for disease gene expression data for Spinal Cord Glioma.

Pathways for Spinal Cord Glioma

GO Terms for Spinal Cord Glioma

Biological processes related to Spinal Cord Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 social behavior GO:0035176 8.96 GNB1L NRXN2
2 regulation of neural precursor cell proliferation GO:2000177 8.62 NF2 PTBP2

Sources for Spinal Cord Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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