MCID: SPN043
MIFTS: 27

Spinal Cord Glioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Spinal Cord Glioma

MalaCards integrated aliases for Spinal Cord Glioma:

Name: Spinal Cord Glioma 12 15
Glial Tumor of Spinal Cord 12 73
Glial Neoplasm Spinal Cord 12
Glioma of Spinal Cord 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3185
NCIt 50 C4534
SNOMED-CT 68 254947008

Summaries for Spinal Cord Glioma

Disease Ontology : 12 A spinal cancer that is located in the spinal cord and has material basis in glial cells.

MalaCards based summary : Spinal Cord Glioma, also known as glial tumor of spinal cord, is related to spinal cord ependymoma and glioma. An important gene associated with Spinal Cord Glioma is NRXN2 (Neurexin 2). Affiliated tissues include the spinal cord, spinal cord and brain, and related phenotypes are nervous system and respiratory system

Related Diseases for Spinal Cord Glioma

Diseases related to Spinal Cord Glioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 spinal cord ependymoma 31.7 HOXB13 RBM10
2 glioma 10.5
3 male reproductive organ cancer 10.0 HOXB13 TP53
4 glioma susceptibility 1 9.8
5 pneumothorax 9.8
6 pulmonary tuberculosis 9.8
7 glioblastoma multiforme 9.8
8 rhabdomyosarcoma 9.8
9 glioblastoma 9.8
10 myoclonus 9.8
11 spinal cancer 9.6 HOXB13 NRXN2 TP53
12 adult medulloblastoma 9.6 TP53 TUBB3
13 female reproductive organ cancer 9.4 TP53 TUBB3
14 nervous system cancer 9.3 TP53 TUBB3
15 respiratory system cancer 9.2 TP53 TUBB3
16 cell type cancer 9.0 TP53 TUBB3

Graphical network of the top 20 diseases related to Spinal Cord Glioma:



Diseases related to Spinal Cord Glioma

Symptoms & Phenotypes for Spinal Cord Glioma

MGI Mouse Phenotypes related to Spinal Cord Glioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.43 GNB1L HOXB13 NRXN2 PTBP2 TP53 TUBB3
2 respiratory system MP:0005388 8.92 NRXN2 PTBP2 TP53 TUBB3

Drugs & Therapeutics for Spinal Cord Glioma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently Recruiting NCT03496181 Not Applicable

Search NIH Clinical Center for Spinal Cord Glioma

Genetic Tests for Spinal Cord Glioma

Anatomical Context for Spinal Cord Glioma

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Cord Glioma:

19
The Spinal Cord

MalaCards organs/tissues related to Spinal Cord Glioma:

41
Spinal Cord, Brain

Publications for Spinal Cord Glioma

Articles related to Spinal Cord Glioma:

(show all 29)
# Title Authors Year
1
Impact of H3.3 K27M Mutation on Prognosis and Survival of Grade IV Spinal Cord Glioma on the Basis of New 2016 World Health Organization Classification of the Central Nervous System. ( 29718432 )
2018
2
Canine spinal cord glioma. ( 28074710 )
2017
3
Convection-enhanced delivery of a hydrophilic nitrosourea ameliorates deficits and suppresses tumor growth in experimental spinal cord glioma models. ( 28247160 )
2017
4
Letter to the Editor: High-grade spinal cord glioma. ( 26895525 )
2016
5
Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. ( 27191809 )
2016
6
A Case of Congenital Malignant Spinal Cord Glioma as a Cause of Congenital Ascites in a Neonate. ( 27597917 )
2016
7
Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. ( 26671631 )
2015
8
Long-term cure of high-grade spinal cord glioma in a pediatric patient who underwent cordectomy. ( 26252785 )
2015
9
Unique microenvironmental responses to PDGF stimulation in brain and spinal cord gliomas determine tumor phenotype. ( 25868602 )
2015
10
Delayed development of a rhabdomyosarcoma following radiation for a spinal cord glioma. ( 23296545 )
2013
11
Spinal cord glioma metastasizing to the brain. ( 22529250 )
2012
12
Platelet-derived growth factor receptor (PDGFR) expression in primary spinal cord gliomas. ( 21789698 )
2012
13
Animal model of intramedullary spinal cord glioma using human glioblastoma multiforme neurospheres. ( 22195609 )
2012
14
Temozolomide for malignant primary spinal cord glioma: an experience of six cases and a literature review. ( 20526650 )
2011
15
Establishment of intramedullary spinal cord glioma model in rats. ( 21034632 )
2010
16
Targeted therapy of spinal cord glioma with a genetically modified Salmonella typhimurium. ( 19922490 )
2010
17
Primary spinal cord glioma: a Surveillance, Epidemiology, and End Results database study. ( 19898743 )
2010
18
Paroxysmal Kinesigenic Segmental Myoclonus due to a spinal cord glioma. ( 17595044 )
2007
19
Radiation-induced spinal cord glioma subsequent to treatment of Hodgkin's disease: case report and review. ( 16158216 )
2006
20
Spinal cord glioma in a ridge-nosed rattlesnake (Crotalus willardi). ( 17323575 )
2005
21
The prognostic value of neurologic function in astrocytic spinal cord glioma. ( 12816727 )
2003
22
A retrospective analysis of 52 cases of spinal cord glioma managed with radiation therapy. ( 11020582 )
2000
23
Spinal cord gliomas: management and outcome with reference to adjuvant therapy. ( 10847645 )
2000
24
Prognostic factors and survival in patients with spinal cord gliomas after radiation therapy. ( 10440187 )
1999
25
The role of radiotherapy in the management of spinal cord glioma. ( 7673019 )
1995
26
MRI of radiation induced spinal cord glioma. ( 2234396 )
1990
27
Intramedullary spinal cord glioma with intracranial seeding. ( 3998737 )
1985
28
Spinal cord glioma following irradiation for Hodgkin's disease. ( 7370950 )
1980
29
Spinal cord glioma after multiple fluoroscopies during artificial pneumothorax treatment of pulmonary tuberculosis: case report. ( 7381543 )
1980

Variations for Spinal Cord Glioma

Expression for Spinal Cord Glioma

Search GEO for disease gene expression data for Spinal Cord Glioma.

Pathways for Spinal Cord Glioma

GO Terms for Spinal Cord Glioma

Biological processes related to Spinal Cord Glioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 social behavior GO:0035176 8.62 GNB1L NRXN2

Sources for Spinal Cord Glioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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