MCID: SPN026
MIFTS: 26

Spinal Cord Lymphoma

Categories: Blood diseases, Cancer diseases, Immune diseases, Neuronal diseases

Aliases & Classifications for Spinal Cord Lymphoma

MalaCards integrated aliases for Spinal Cord Lymphoma:

Name: Spinal Cord Lymphoma 12 15
Lymphoma of the Spinal Cord 12
Spinal Cord--Cancer 71
Spinal Cord Cancer 12
Spine Lymphoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14150
NCIt 49 C5157
ICD10 32 C72.0
UMLS 71 C1336044 C1658125

Summaries for Spinal Cord Lymphoma

Disease Ontology : 12 A spinal cancer that is located in the spinal cord and derives from lymphocytes.

MalaCards based summary : Spinal Cord Lymphoma, also known as lymphoma of the spinal cord, is related to central nervous system lymphoma and spinal cancer. An important gene associated with Spinal Cord Lymphoma is CNST (Consortin, Connexin Sorting Protein). The drugs Olaparib and Durvalumab have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, eye and brain.

Related Diseases for Spinal Cord Lymphoma

Graphical network of the top 20 diseases related to Spinal Cord Lymphoma:



Diseases related to Spinal Cord Lymphoma

Symptoms & Phenotypes for Spinal Cord Lymphoma

Drugs & Therapeutics for Spinal Cord Lymphoma

Drugs for Spinal Cord Lymphoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Olaparib Approved Phase 2 763113-22-0 23725625
2
Durvalumab Approved, Investigational Phase 2 1428935-60-7
3 Poly(ADP-ribose) Polymerase Inhibitors Phase 2
4 Tin Fluorides Phase 2
5 Antineoplastic Agents, Immunological Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cyberknife Precision Radiation Delivery System for Tumors of the Spine Completed NCT00185666 Phase 1, Phase 2
2 A Phase II Study of Olaparib and Durvalumab (MEDI 4736) in Patients With IDH-Mutated Solid Tumors Not yet recruiting NCT03991832 Phase 2 Olaparib;Durvalumab

Search NIH Clinical Center for Spinal Cord Lymphoma

Genetic Tests for Spinal Cord Lymphoma

Anatomical Context for Spinal Cord Lymphoma

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Cord Lymphoma:

19
Spinal Cord

MalaCards organs/tissues related to Spinal Cord Lymphoma:

40
Spinal Cord, Eye, Brain, Kidney, T Cells, B Cells

Publications for Spinal Cord Lymphoma

Articles related to Spinal Cord Lymphoma:

(show all 25)
# Title Authors PMID Year
1
Nomograms Predict Survival Outcome of Primary Intramedullary Spinal Cord Lymphoma Patients. 61
31579048 2019
2
Primary Intramedullary Spinal Cord Lymphoma Presenting as a Cervical Ring-Enhancing Lesion in an AIDS Patient. 61
29951566 2018
3
Primary B-cell Spinal Cord Lymphoma of the Cervical Spine. 61
30152771 2018
4
Percutaneous Vertebroplasty for Primary Non-Hodgkin's Lymphoma of the Thoracic Spine: Case Report and Review of the Literature. 61
28727717 2017
5
Primary intramedullary spinal cord lymphoma: a population-based study. 61
28011925 2017
6
A rare cause of spinal mass: primary intramedullary spinal cord lymphoma. 61
26070282 2015
7
Primary CNS T-cell lymphoma of the spinal cord: case report and literature review. 61
25918197 2015
8
Primary intramedullary non-Hodgkin's lymphoma in an immunocompetent child. 61
25082378 2014
9
Concurrent primary vitreoretinal and spinal cord lymphoma: a unique entity. 61
25010176 2014
10
Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report. 61
24107866 2013
11
Tuberculosis of the spine masquerading as a spine lymphoma. A case report and discussion of diagnostic and therapeutic traps. 61
23650010 2013
12
Spinal cord tumors: new views and future directions. 61
23186903 2013
13
Primary intramedullary spinal cord lymphoma. 61
22728074 2012
14
Primary intramedullary spinal cord lymphoma. 61
21832220 2011
15
[Therapeutic management of central nervous system lymphomas in a single hematological institute]. 61
19812012 2009
16
[Primary intramedullary lymphoma. Case report]. 61
17689569 2007
17
Human herpesvirus 8-associated spinal cord lymphoma in an HIV-positive subject. 61
16916728 2006
18
Central nervous system lymphoproliferative disorder in pediatric kidney transplant recipients. 61
16712612 2006
19
[Primary intramedullary spinal cord lymphoma in HIV patients. MRI aspects]. 61
10637928 1999
20
[Spinal cord lymphoma]. 61
10609464 1999
21
Spinal cord lesions in patients with AIDS. 61
9113695 1997
22
Primary spinal cord lymphoma: MR appearance. 61
2398167 1990
23
Primary CNS lymphoma: lymphomatous meningitis presenting as a cauda equina lesion in an AIDS patient. 61
2207891 1990
24
Primary intramedullary spinal cord lymphoma: report of a case. 61
2432294 1986
25
Primary lymphoma of the spinal cord. 61
7086466 1982

Variations for Spinal Cord Lymphoma

Expression for Spinal Cord Lymphoma

Search GEO for disease gene expression data for Spinal Cord Lymphoma.

Pathways for Spinal Cord Lymphoma

GO Terms for Spinal Cord Lymphoma

Biological processes related to Spinal Cord Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein localization GO:0008104 8.62 TRAK2 BCL6

Sources for Spinal Cord Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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