MCID: SPN026
MIFTS: 26

Spinal Cord Lymphoma

Categories: Blood diseases, Cancer diseases, Immune diseases, Neuronal diseases

Aliases & Classifications for Spinal Cord Lymphoma

MalaCards integrated aliases for Spinal Cord Lymphoma:

Name: Spinal Cord Lymphoma 12 15
Lymphoma of the Spinal Cord 12
Spinal Cord--Cancer 71
Spinal Cord Cancer 12
Spine Lymphoma 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14150
NCIt 50 C5157
ICD10 32 C72.0
UMLS 71 C1336044 C1658125

Summaries for Spinal Cord Lymphoma

Disease Ontology : 12 A spinal cancer that is located in the spinal cord and derives from lymphocytes.

MalaCards based summary : Spinal Cord Lymphoma, also known as lymphoma of the spinal cord, is related to central nervous system lymphoma and follicular lymphoma. An important gene associated with Spinal Cord Lymphoma is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways is IgA-Producing B Cells in the Intestine. Affiliated tissues include spinal cord, eye and brain.

Related Diseases for Spinal Cord Lymphoma

Diseases related to Spinal Cord Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 central nervous system lymphoma 29.8 CCR6 BCL6
2 follicular lymphoma 29.3 CR1 BCL6
3 spinal cancer 11.4
4 spinal meningioma 11.0
5 blastomycosis 10.1 CCR6 CABP1
6 lymphoma 10.1
7 viral pneumonia 10.0 CR1 CCR6
8 pyelitis 10.0 HAVCR1 CCR6
9 ureteral disease 10.0 HAVCR1 CCR6
10 acute cystitis 10.0 HAVCR1 CCR6
11 burkitt lymphoma 10.0
12 anaplastic large cell lymphoma 10.0
13 peripheral t-cell lymphoma 10.0
14 cauda equina syndrome 10.0
15 lymphosarcoma 10.0
16 primary central nervous system lymphoma 10.0
17 urinary tract obstruction 10.0 HAVCR1 CCR6
18 adult xanthogranuloma 10.0 HAVCR1 CR1
19 human immunodeficiency virus type 1 9.9
20 human herpesvirus 8 9.9
21 diffuse large b-cell lymphoma 9.9
22 demyelinating disease 9.9
23 b-cell lymphoma 9.9
24 chest wall lymphoma 9.9 CCR6 BCL6
25 cll/sll 9.9 CCR6 BCL6
26 spinal cord glioma 9.9
27 decubitus ulcer 9.9
28 glioma 9.9
29 glial tumor 9.9
30 central nervous system hematologic cancer 9.9 CCR6 BCL6
31 splenic disease 9.9 CCR6 BCL6
32 marginal zone b-cell lymphoma 9.8 CCR6 BCL6
33 mature t-cell and nk-cell lymphoma 9.8 CCR6 BCL6
34 t-cell/histiocyte rich large b cell lymphoma 9.8 CR1 BCL6
35 mature b-cell neoplasm 9.8 CCR6 BCL6
36 sezary's disease 9.8 CCR6 BCL6
37 lymphoma, mucosa-associated lymphoid type 9.8 CCR6 BCL6
38 acquired immunodeficiency syndrome 9.7 CCR6 BCL6
39 lymphoproliferative syndrome 9.6 CCR6 BCL6
40 lymphatic system cancer 9.5 CCR6 BCL6
41 leukemia, chronic lymphocytic 9.5 CR1 CCR6 BCL6
42 systemic lupus erythematosus 9.2 HAVCR1 CR1 CCR6 BCL6

Graphical network of the top 20 diseases related to Spinal Cord Lymphoma:



Diseases related to Spinal Cord Lymphoma

Symptoms & Phenotypes for Spinal Cord Lymphoma

Drugs & Therapeutics for Spinal Cord Lymphoma

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cyberknife Precision Radiation Delivery System for Tumors of the Spine Completed NCT00185666 Phase 1, Phase 2

Search NIH Clinical Center for Spinal Cord Lymphoma

Genetic Tests for Spinal Cord Lymphoma

Anatomical Context for Spinal Cord Lymphoma

The Foundational Model of Anatomy Ontology organs/tissues related to Spinal Cord Lymphoma:

19
Spinal Cord

MalaCards organs/tissues related to Spinal Cord Lymphoma:

40
Spinal Cord, Eye, Brain, Kidney

Publications for Spinal Cord Lymphoma

Articles related to Spinal Cord Lymphoma:

(show all 25)
# Title Authors PMID Year
1
Nomograms Predict Survival Outcome of Primary Intramedullary Spinal Cord Lymphoma Patients. 61
31579048 2019
2
Primary B-cell Spinal Cord Lymphoma of the Cervical Spine. 61
30152771 2018
3
Primary Intramedullary Spinal Cord Lymphoma Presenting as a Cervical Ring-Enhancing Lesion in an AIDS Patient. 61
29951566 2018
4
Percutaneous Vertebroplasty for Primary Non-Hodgkin's Lymphoma of the Thoracic Spine: Case Report and Review of the Literature. 61
28727717 2017
5
Primary intramedullary spinal cord lymphoma: a population-based study. 61
28011925 2017
6
A rare cause of spinal mass: primary intramedullary spinal cord lymphoma. 61
26070282 2015
7
Primary CNS T-cell lymphoma of the spinal cord: case report and literature review. 61
25918197 2015
8
Primary intramedullary non-Hodgkin's lymphoma in an immunocompetent child. 61
25082378 2014
9
Concurrent primary vitreoretinal and spinal cord lymphoma: a unique entity. 61
25010176 2014
10
Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report. 61
24107866 2013
11
Tuberculosis of the spine masquerading as a spine lymphoma. A case report and discussion of diagnostic and therapeutic traps. 61
23650010 2013
12
Spinal cord tumors: new views and future directions. 61
23186903 2013
13
Primary intramedullary spinal cord lymphoma. 61
22728074 2012
14
Primary intramedullary spinal cord lymphoma. 61
21832220 2011
15
[Therapeutic management of central nervous system lymphomas in a single hematological institute]. 61
19812012 2009
16
[Primary intramedullary lymphoma. Case report]. 61
17689569 2007
17
Human herpesvirus 8-associated spinal cord lymphoma in an HIV-positive subject. 61
16916728 2006
18
Central nervous system lymphoproliferative disorder in pediatric kidney transplant recipients. 61
16712612 2006
19
[Primary intramedullary spinal cord lymphoma in HIV patients. MRI aspects]. 61
10637928 1999
20
[Spinal cord lymphoma]. 61
10609464 1999
21
Spinal cord lesions in patients with AIDS. 61
9113695 1997
22
Primary spinal cord lymphoma: MR appearance. 61
2398167 1990
23
Primary CNS lymphoma: lymphomatous meningitis presenting as a cauda equina lesion in an AIDS patient. 61
2207891 1990
24
Primary intramedullary spinal cord lymphoma: report of a case. 61
2432294 1986
25
Primary lymphoma of the spinal cord. 61
7086466 1982

Variations for Spinal Cord Lymphoma

Expression for Spinal Cord Lymphoma

Search GEO for disease gene expression data for Spinal Cord Lymphoma.

Pathways for Spinal Cord Lymphoma

Pathways related to Spinal Cord Lymphoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.62 CR1 CCR6 BCL6

GO Terms for Spinal Cord Lymphoma

Cellular components related to Spinal Cord Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.8 HAVCR1 CR1 CCR6

Biological processes related to Spinal Cord Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral entry into host cell GO:0046718 8.96 HAVCR1 CR1
2 positive regulation of regulatory T cell differentiation GO:0045591 8.62 CR1 BCL6

Molecular functions related to Spinal Cord Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 virus receptor activity GO:0001618 8.62 HAVCR1 CR1

Sources for Spinal Cord Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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