MCID: SPN025
MIFTS: 21

Spinal Cord Melanoma

Categories: Cancer diseases, Neuronal diseases, Skin diseases

Aliases & Classifications for Spinal Cord Melanoma

MalaCards integrated aliases for Spinal Cord Melanoma:

Name: Spinal Cord Melanoma 12 15 71
Melanoma of the Spinal Cord 12

Classifications:



External Ids:

Disease Ontology 12 DOID:14151
NCIt 50 C5158
UMLS 71 C1336045

Summaries for Spinal Cord Melanoma

MalaCards based summary : Spinal Cord Melanoma, also known as melanoma of the spinal cord, is related to melanoma and skin melanoma. An important gene associated with Spinal Cord Melanoma is MLANA (Melan-A). Affiliated tissues include spinal cord, and related phenotypes are no phenotypic analysis and pigmentation

Related Diseases for Spinal Cord Melanoma

Diseases related to Spinal Cord Melanoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 melanoma 29.8 TYR MLANA IFNB1 HGF
2 skin melanoma 29.3 TYR MLANA MKI67
3 conjunctival pigmentation 10.1 MLANA CD68
4 sarcomatoid squamous cell skin carcinoma 10.1 MLANA CD68
5 skin sarcoma 10.1 MLANA CD68
6 balloon cell malignant melanoma 10.1 MLANA CD68
7 malignant granular cell myoblastoma 10.1 MLANA CD68
8 intravascular fasciitis 10.1 MLANA CD68
9 bladder sarcoma 10.1 MLANA CD68
10 cutaneous fibrous histiocytoma 10.1 MLANA CD68
11 granular cell tumor 10.1 MLANA CD68
12 mesenchymal cell neoplasm 10.1 MLANA CD68
13 papillary thyroid microcarcinoma 10.0 MKI67 HGF
14 connective tissue benign neoplasm 10.0 MLANA CD68
15 vascular cancer 10.0 MLANA CD68
16 subleukemic leukemia 10.0 OLIG2 MLANA
17 quadriplegia 10.0
18 extrinsic cardiomyopathy 10.0 IFNB1 CD68
19 angiosarcoma 10.0 MLANA CD68
20 malignant leptomeningeal tumor 9.9 TYR MLANA
21 meningeal melanoma 9.9 TYR MLANA
22 ciliary body cancer 9.9 TYR MLANA
23 melanoacanthoma 9.9 TYR MLANA
24 halo nevi 9.9 TYR MLANA
25 melanomatosis 9.9 TYR MLANA
26 epithelioid cell melanoma 9.9 TYR MLANA
27 central neurocytoma 9.9 OLIG2 MKI67
28 orbit rhabdomyosarcoma 9.9 TYR MLANA
29 hydrocephalus 9.9
30 benign ependymoma 9.9
31 cellular ependymoma 9.9
32 back pain 9.9
33 paresthesia 9.9
34 malignant fibrous histiocytoma 9.9 MKI67 CD68
35 nodular malignant melanoma 9.9 TYR MLANA
36 orofacial cleft 8 9.9 TYR MLANA
37 diffuse astrocytoma 9.9 OLIG2 MKI67
38 amelanotic melanoma 9.9 TYR MLANA
39 keratosis, seborrheic 9.9 TYR MLANA
40 angiomyolipoma 9.9 TYR MLANA
41 clear cell sarcoma 9.9 TYR MLANA
42 inflammatory myofibroblastic tumor 9.9 MKI67 CD68
43 vitiligo-associated multiple autoimmune disease susceptibility 1 9.8 TYR MLANA
44 ocular albinism 9.8 TYR MLANA
45 autoimmune disease of central nervous system 9.8 OLIG2 IFNB1
46 sarcoma, synovial 9.8 MKI67 HGF
47 ectodermal dysplasia 10b, hypohidrotic/hair/tooth type, autosomal recessive 9.8 OLIG2 CD68
48 diffuse meningeal melanocytosis 9.7 TYR MLANA HGF
49 neurofibroma 9.7 TYR MLANA HGF
50 sarcomatoid transitional cell carcinoma 9.7 TYR MLANA CD68

Graphical network of the top 20 diseases related to Spinal Cord Melanoma:



Diseases related to Spinal Cord Melanoma

Symptoms & Phenotypes for Spinal Cord Melanoma

MGI Mouse Phenotypes related to Spinal Cord Melanoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 no phenotypic analysis MP:0003012 9.7 CD68 HGF IFNB1 MKI67 MLANA OLIG2
2 pigmentation MP:0001186 9.13 HGF MLANA TYR
3 skeleton MP:0005390 9.02 CD68 HGF IFNB1 OLIG2 TYR

Drugs & Therapeutics for Spinal Cord Melanoma

Search Clinical Trials , NIH Clinical Center for Spinal Cord Melanoma

Genetic Tests for Spinal Cord Melanoma

Anatomical Context for Spinal Cord Melanoma

MalaCards organs/tissues related to Spinal Cord Melanoma:

40
Spinal Cord

Publications for Spinal Cord Melanoma

Articles related to Spinal Cord Melanoma:

(show all 33)
# Title Authors PMID Year
1
Primary spinal melanoma: A case report. 61
33581992 2021
2
Hydrocephalus Secondary to Intradural Extramedullary Malignant Melanoma of Spinal Cord. 61
31302270 2019
3
Primary Spinal Cord Melanoma of Intradural Extramedullary Origin. 61
31595127 2019
4
Primary Spinal Cord Melanoma - An Uncommon Entity. 61
31084668 2019
5
5-Aminolevulinic acid fluorescence-guided surgery for spinal cord melanoma metastasis: a technical note. 61
30091052 2018
6
Primary Spinal Cord Melanoma: A Case Report and a Systemic Review of Overall Survival. 61
29614357 2018
7
A rare case of primary spinal cord melanoma. 61
29904488 2018
8
Multifocal primary melanoma of the cervical spinal cord successfully treated by tumorectomy: a case report. 61
29581891 2018
9
18F-fluoroethyl-L-tyrosine positron emission tomography-guided diagnosis of a malignant intramedullary spinal cord tumor. 61
28105177 2016
10
Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine. 61
27127667 2016
11
Primary spinal melanoma treated with adjuvant radiotherapy and concurrent temozolomide: A case report and review of literature. 61
26881599 2015
12
An uncommon intramedullary tumor: primary spinal cord melanoma. 61
25187871 2014
13
Primary melanocytic tumors of the central nervous system: Report of two cases and review of literature. 61
25371847 2014
14
Primary spinal cord melanoma in thoracic spine with leptomeningeal dissemination and presenting hydrocephalus. 61
24904904 2013
15
Primary melanoma of the spinal cord: a case report. 61
23905124 2013
16
Multiple spinal cord melanoma: case report with emphasis on the difficult preoperative diagnosis. 61
24101278 2013
17
Primary melanoma of the spinal cord: a case report, molecular footprint, and review of the literature. 61
21444862 2011
18
Primary spinal cord melanoma. 61
20856666 2010
19
Primary intradural extramedullary melanoma of the cervical spinal cord: case report. 61
20308942 2010
20
Primary spinal cord melanoma - a case report. 61
20925006 2010
21
Primary intraparenchymatous spinal cord melanoma. 61
9601119 1998
22
[Primary intramedullary melanoma. Apropos of a case]. 61
8767918 1996
23
Primary spinal intramedullary malignant melanoma: case report. 61
2755570 1989
24
Primary spinal melanoma. 61
3783259 1987
25
[A case contribution on the question of primary intramedullary melanoma]. 61
545687 1979
26
Statistical study on malignant melanoma in Japan (1970-1976). 61
867422 1977
27
[Melanoma of the spinal cord in pregnancy (author's transl)]. 61
1239681 1975
28
[Surgical treatment of primary melanoma of the spinal cord]. 61
5997662 1966
29
[On melanoblastoma and melanoma of the spinal cord]. 61
5997669 1966
30
[A case of primary melanoma of the spinal cord]. 61
5856015 1965
31
Primary melanoma of the spinal cord. 61
13755836 1961
32
Primary malignant melanoma of the spinal cord. 61
13714515 1960
33
Primary malignant melanoma of the spinal cord. 61
14943319 1952

Variations for Spinal Cord Melanoma

Expression for Spinal Cord Melanoma

Search GEO for disease gene expression data for Spinal Cord Melanoma.

Pathways for Spinal Cord Melanoma

GO Terms for Spinal Cord Melanoma

Cellular components related to Spinal Cord Melanoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 melanosome GO:0042470 8.62 TYR MLANA

Sources for Spinal Cord Melanoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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