MCID: SPN045
MIFTS: 19

Spinal Cord Primitive Neuroectodermal Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Spinal Cord Primitive Neuroectodermal Neoplasm

MalaCards integrated aliases for Spinal Cord Primitive Neuroectodermal Neoplasm:

Name: Spinal Cord Primitive Neuroectodermal Neoplasm 12 15
Spinal Cord Primitive Neuroectodermal Tumor 70
Spinal Cord Pnet 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6872
NCIt 50 C5406
UMLS 70 C1336048

Summaries for Spinal Cord Primitive Neuroectodermal Neoplasm

MalaCards based summary : Spinal Cord Primitive Neuroectodermal Neoplasm, also known as spinal cord primitive neuroectodermal tumor, is related to spastic paraplegia 33, autosomal dominant and spastic paraplegia 12, autosomal dominant. An important gene associated with Spinal Cord Primitive Neuroectodermal Neoplasm is ZFYVE27 (Zinc Finger FYVE-Type Containing 27), and among its related pathways/superpathways are Endocytosis and TGF-beta Signaling Pathway (WikiPathways). Affiliated tissues include spinal cord.

Related Diseases for Spinal Cord Primitive Neuroectodermal Neoplasm

Graphical network of the top 20 diseases related to Spinal Cord Primitive Neuroectodermal Neoplasm:



Diseases related to Spinal Cord Primitive Neuroectodermal Neoplasm

Symptoms & Phenotypes for Spinal Cord Primitive Neuroectodermal Neoplasm

Drugs & Therapeutics for Spinal Cord Primitive Neuroectodermal Neoplasm

Search Clinical Trials , NIH Clinical Center for Spinal Cord Primitive Neuroectodermal Neoplasm

Genetic Tests for Spinal Cord Primitive Neuroectodermal Neoplasm

Anatomical Context for Spinal Cord Primitive Neuroectodermal Neoplasm

MalaCards organs/tissues related to Spinal Cord Primitive Neuroectodermal Neoplasm:

40
Spinal Cord

Publications for Spinal Cord Primitive Neuroectodermal Neoplasm

Articles related to Spinal Cord Primitive Neuroectodermal Neoplasm:

# Title Authors PMID Year
1
Intramedullary spinal cord primitive neuroectodermal tumor presenting with hydrocephalus. 61
22532539 2013
2
Fanconi anemia and biallelic BRCA2 mutation diagnosed in a young child with an embryonal CNS tumor. 61
19530235 2009
3
Purely intramedullary spinal cord primitive neuroectodermal tumor: case report and review of the literature. 61
19688140 2009
4
FDG imaging of spinal cord primitive neuroectodermal tumor. 61
9669395 1998
5
Primary intramedullary spinal cord primitive neuroectodermal tumor with intracranial seeding in an infant. 61
8934026 1996
6
Intracranial metastasis from a spinal cord primitive neuroectodermal tumor: case report. 61
1317609 1992

Variations for Spinal Cord Primitive Neuroectodermal Neoplasm

Expression for Spinal Cord Primitive Neuroectodermal Neoplasm

Search GEO for disease gene expression data for Spinal Cord Primitive Neuroectodermal Neoplasm.

Pathways for Spinal Cord Primitive Neuroectodermal Neoplasm

Pathways related to Spinal Cord Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 ZFYVE9 ZFYVE27 HGS CHMP1B
2 11.08 ZFYVE9 HGS

GO Terms for Spinal Cord Primitive Neuroectodermal Neoplasm

Cellular components related to Spinal Cord Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 early endosome membrane GO:0031901 9.26 ZFYVE9 HGS
2 endosome GO:0005768 9.26 ZFYVE9 ZFYVE27 HGS CHMP1B
3 integral component of endoplasmic reticulum membrane GO:0030176 9.16 ZFYVE27 RTN1
4 endoplasmic reticulum tubular network GO:0071782 8.62 ZFYVE27 REEP1

Biological processes related to Spinal Cord Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endosomal transport GO:0016197 8.96 ZFYVE9 HGS
2 multivesicular body assembly GO:0036258 8.62 HGS CHMP1B

Molecular functions related to Spinal Cord Primitive Neuroectodermal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein domain specific binding GO:0019904 8.8 ZFYVE9 HGS CHMP1B

Sources for Spinal Cord Primitive Neuroectodermal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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