Aliases & Classifications for Spinal Disease

MalaCards integrated aliases for Spinal Disease:

Name: Spinal Disease 12 15
Spinal Disorder 55
Spinal Diseases 73

External Ids:

Disease Ontology 12 DOID:0060564
UMLS 73 C0037933

Summaries for Spinal Disease

MalaCards based summary : Spinal Disease, also known as spinal disorder, is related to spondyloarthropathy 1 and sacral agenesis with vertebral anomalies, and has symptoms including back pain, sciatica and acute back pain. An important gene associated with Spinal Disease is SMN1 (Survival Of Motor Neuron 1, Telomeric), and among its related pathways/superpathways are Hepatitis C and Hepatocellular Carcinoma and Differentiation Pathway. The drugs Lidocaine and Dexmedetomidine have been mentioned in the context of this disorder. Affiliated tissues include bone, spinal cord and testes.

Wikipedia : 76 Spinal disease (also known as a dorsopathy) refers to a condition impairing the backbone. These include... more...

Related Diseases for Spinal Disease

Diseases related to Spinal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 spondyloarthropathy 1 28.4 CRP MRAP
2 sacral agenesis with vertebral anomalies 11.3
3 cold agglutinin disease 10.8 CRP IL6
4 cryopyrin-associated periodic syndrome 10.7 CRP IL6
5 cardiogenic shock 10.7 CRP IL6
6 acute cholangitis 10.7 CRP IL6
7 neutrophilia, hereditary 10.7 CRP IL6
8 uremic pruritus 10.7 CRP IL6
9 castleman disease 10.7 CRP IL6
10 angina pectoris 10.7 CRP IL6
11 viral pneumonia 10.7 CRP IL6
12 cecal disease 10.7 CRP IL6
13 relapsing polychondritis 10.7 CRP IL6
14 central nervous system vasculitis 10.7 CRP IL6
15 subacute thyroiditis 10.7 CRP IL6
16 intussusception 10.7 CRP IL6
17 louse-borne relapsing fever 10.7 CRP IL6
18 multicentric castleman disease 10.7 CRP IL6
19 hypersensitivity reaction type iii disease 10.7 CRP IL6
20 critical limb ischemia 10.7 IL6 VEGFA
21 ischemic heart disease 10.7 CRP IL6
22 alexithymia 10.7 CRP IL6
23 intermittent explosive disorder 10.7 CRP IL6
24 intermediate coronary syndrome 10.7 CRP IL6
25 acute cystitis 10.7 CRP IL6
26 pulmonary aspergilloma 10.7 CRP VEGFA
27 systolic heart failure 10.7 CRP IL6
28 poems syndrome 10.7 IL6 VEGFA
29 polyarteritis nodosa 10.7 CRP IL6
30 prediabetes syndrome 10.7 CRP IL6
31 acute pyelonephritis 10.6 CRP IL6
32 apnea, obstructive sleep 10.6 CRP IL6
33 adult-onset still's disease 10.6 CRP IL6
34 primary effusion lymphoma 10.6 IL6 VEGFA
35 perinatal necrotizing enterocolitis 10.6 CRP IL6
36 viral meningitis 10.6 CRP IL6
37 spindle cell sarcoma 10.6 IL6 VEGFA
38 central retinal vein occlusion 10.6 IL6 VEGFA
39 eales disease 10.6 IL6 VEGFA
40 infective endocarditis 10.6 CRP IL6
41 hemorrhagic fever with renal syndrome 10.6 CRP IL6
42 lymph node disease 10.6 CRP IL6
43 rosacea 10.6 IL6 VEGFA
44 exanthem 10.6 CRP IL6
45 uterine anomalies 10.6 CRP IL6
46 bladder disease 10.6 CRP IL6
47 diabetic macular edema 10.6 IL6 VEGFA
48 leptospirosis 10.6 CRP IL6
49 pancreas disease 10.5 CRP IL6
50 discitis 10.5 CRP IVD

Graphical network of the top 20 diseases related to Spinal Disease:



Diseases related to Spinal Disease

Symptoms & Phenotypes for Spinal Disease

UMLS symptoms related to Spinal Disease:


back pain, sciatica, acute back pain

Drugs & Therapeutics for Spinal Disease

Drugs for Spinal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 425)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Not Applicable,Early Phase 1 137-58-6 3676
2
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 113775-47-6 68602 5311068
3
Dopamine Approved Phase 4,Phase 2,Phase 3,Not Applicable 51-61-6, 62-31-7 681
4
Norepinephrine Approved Phase 4,Not Applicable 51-41-2 439260
5
Thrombin Approved, Investigational Phase 4
6
Adalimumab Approved Phase 4,Phase 3,Phase 2,Not Applicable 331731-18-1 16219006
7
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 185243-69-0
8
Celecoxib Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 169590-42-5 2662
9
Sulfasalazine Approved Phase 4,Phase 2,Phase 3,Phase 1 599-79-1 5353980 5359476
10
Pamidronate Approved Phase 4,Phase 2 40391-99-9 4674
11
Ethambutol Approved Phase 4 74-55-5 3279 14052
12
Isoniazid Approved, Investigational Phase 4 54-85-3 3767
13
Pyrazinamide Approved, Investigational Phase 4 98-96-4 1046
14
Rifampicin Approved Phase 4,Phase 3 13292-46-1 5458213 5381226
15
Certolizumab pegol Approved Phase 4,Phase 3,Phase 2,Phase 1 428863-50-7
16
Infliximab Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 170277-31-3
17
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 1994-09-7, 94-09-7 2337
18
Menthol Approved Phase 4,Phase 3,Phase 1,Not Applicable 2216-51-5 16666
19
Tranexamic Acid Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1197-18-8 5526
20
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 2078-54-8 4943
21
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Not Applicable 15307-86-5 3033
22
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1959-05-2, 59-05-2 126941
23
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 83-43-2 6741
24
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1,Not Applicable 50-24-8 5755
25
Triamcinolone Approved, Vet_approved Phase 4,Early Phase 1,Not Applicable 124-94-7 31307
26
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 60142-96-3 3446
27
gamma-Aminobutyric acid Approved, Investigational Phase 4,Phase 3,Phase 2,Early Phase 1 56-12-2 119
28
Teriparatide Approved, Investigational Phase 4,Not Applicable 52232-67-4 16133850
29
Naloxone Approved, Vet_approved Phase 4,Not Applicable 465-65-6 5284596
30
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
31
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 52485-79-7 40400 644073
32
Bupivacaine Approved, Investigational Phase 4,Phase 3,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
33
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
34
Tramadol Approved, Investigational Phase 4,Phase 3,Not Applicable 27203-92-5 33741
35
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 57-27-2 5288826
36
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
37
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 59467-70-8 4192
38
Remifentanil Approved Phase 4,Phase 3,Phase 2,Not Applicable 132875-61-7 60815
39
Aminocaproic Acid Approved, Investigational Phase 4,Not Applicable 60-32-2 564
40
Diphenhydramine Approved, Investigational Phase 4 147-24-0, 58-73-1 3100
41
Histamine Approved, Investigational Phase 4,Not Applicable 75614-87-8, 51-45-6 774
42
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Not Applicable 148553-50-8 5486971
43
Promethazine Approved, Investigational Phase 4 60-87-7 4927
44
Nicardipine Approved, Investigational Phase 4 55985-32-5 4474
45
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 6740-88-1 3821
46
Alprostadil Approved, Investigational Phase 4 745-65-3 149351 5280723
47
Cefuroxime Approved Phase 4 55268-75-2 5361202 5479529
48
Betamethasone Approved, Vet_approved Phase 4,Early Phase 1,Not Applicable 378-44-9 9782
49
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-02-2 5743
50
Aceclofenac Approved, Investigational Phase 4,Not Applicable 89796-99-6

Interventional clinical trials:

(show top 50) (show all 1480)
# Name Status NCT ID Phase Drugs
1 The Effect of Perioperative Lidocaine Intravenous Infusion on Postoperative Recovery After Spine Surgery. Unknown status NCT02762656 Phase 4 Lidocaine
2 The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia Unknown status NCT02535273 Phase 4 Dexmedetomidine;Lidocaine;Low-dose Dexmedetomidine;Moderate-dose Dexmedetomidine;High-dose Dexmedetomidine;normal saline
3 Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery Unknown status NCT02535000 Phase 4 Duloxetine;Placebo
4 Post-Market Surveillance Study of the TM Ardis Interbody Fusion System Unknown status NCT02429908 Phase 4
5 Effect of Human Thrombin With Gelatin Matrix on Perioperative Blood Loss in Scoliosis Surgery Unknown status NCT01451788 Phase 4
6 Evaluation of Bone Union Following Anterior Cervical Fusion Using a NovoMax™ Unknown status NCT02425514 Phase 4
7 Danish Multicenter Study of Adalimumab in Spondyloarthritis Unknown status NCT00477893 Phase 4 Adalimumab;Placebo
8 Treatment of Axial Spondyloarthritis by Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ IgG Fc Fusion Protein Unknown status NCT02364479 Phase 4 etanercept;etanercept (half dose);placebo
9 Dose Reduction of Etanercept in Patients With Ankylosing Spondylitis Unknown status NCT02638896 Phase 4 etanercept (Half-Dose);etanercept (Full-Dose);Sulfasalazine;Celecoxib
10 Etanercept Versus Adalimumab in the Treatment of Patients With Ankylosing Spondylitis. A Switch Study Unknown status NCT02489760 Phase 4
11 Combined Treatment With TNF Inhibitor and Pamidronate in AS Patients: Effect on the Radiographic Progression Unknown status NCT02313727 Phase 4 Pamidronate
12 Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy Unknown status NCT01204008 Phase 4
13 The Optimal Duration of Preoperative Anti-tuberculosis Treatment of Spinal Tuberculosis Unknown status NCT02477852 Phase 4 Isoniazid;Rifampicin;Ethambutol;Pyrazinamide
14 Protocol for H.P. Acthar Gel in Moderately to Severely Active Psoriatic Arthritis Unknown status NCT01939132 Phase 4 Open label H.P. Acthar Gel
15 Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Unknown status NCT02132234 Phase 4 Etanercept;Adalimumab;Certolizumab;Infliximab
16 Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases Unknown status NCT01151644 Phase 4
17 Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker Unknown status NCT01072058 Phase 4 TNF blockers (infliximab, adalimumab, etanercept)
18 An Interventional Study to Assess the Efficacy and Safety of Oxycodone/Naloxone in Korean Patients With Spinal Disorders Completed NCT01811238 Phase 4 Oxycodone/naloxone
19 An Interventional Study to Assess the Efficacy and Safety of Buprenorphine in Korean Patients With Spinal Disorders Completed NCT01818700 Phase 4 Buprenorphine
20 Ultrasound Guided Modified Thoracolumbar Interfascial Plane Block for Spinal Surgery Completed NCT03079076 Phase 4 Bupivacaine;Saline
21 Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery Completed NCT02724111 Phase 4 sufficient dose of rocuronium;sugammadex 10 min after position change
22 Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion Completed NCT00808665 Phase 4 Dexmedetomidine;0.9% Saline
23 Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery Completed NCT02416804 Phase 4 Buprenorphine;Tramadol
24 Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™ Completed NCT01615328 Phase 4
25 The Use of Intrathecal Morphine in the Management of Acute Pain Following Decompressive Lumbar Spinal Surgery Completed NCT01053039 Phase 4 Intrathecal Morphine;Intrathecal Saline
26 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
27 Barricaid EU Post Market Study for Primary Lumbar Disc Herniation Completed NCT01534065 Phase 4
28 Effect of Sugammadex for Muscle Motor Response and Awareness in Intraoperative Wakeup Completed NCT02390817 Phase 4 Sugammadex;Neostigmine
29 Efficacy and Safety of Expandable Spacer in the Treatment of Degenerative Disc Disease Using the Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgical Approach Completed NCT02075554 Phase 4
30 The Effect Site Concentration of Remifentanil for Conscious Sedation During Awake Nasotracheal Fiberoptic Intubation Completed NCT01052324 Phase 4 Remifentanil
31 Comparison of IDD Therapy and Non-surgical Treatment for Low Back Pain Caused by Degenerative Disc Disease Completed NCT00165893 Phase 4
32 Intermittent Epidural Bolus Versus Epidural Infusion for Posterior Spinal Fusion After Adolescent Idiopathic Scoliosis Completed NCT02669004 Phase 4 Intermittent bolus epidural morphine;continuous epidural morphine
33 Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery Completed NCT02063035 Phase 4 Tranexamic Acid;Placebo
34 Blood Propofol Concentrations in Children During Spinal Surgery Completed NCT01932424 Phase 4 Propofol 2% (Diprivan 2%, Astra Zeneca UK)
35 Proximal Junctional Kyphosis Following Long Instrumented Spinal Fusion: The Effect of Implant Selection Completed NCT01441999 Phase 4
36 MiDAS II (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study Completed NCT01082159 Phase 4
37 Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis Completed NCT00995371 Phase 4 Epidural Steroid Injection
38 Tranexamic Acid (TXA) Versus Epsilon Aminocaproic Acid (EACA) Versus Placebo for Spine Surgery Completed NCT00958581 Phase 4 Tranexamic Acid;Normal Saline;Epsilon aminocaproic acid
39 MiDAS I (Mild® Decompression Alternative to Open Surgery): Vertos Mild Patient Evaluation Study Completed NCT00956631 Phase 4
40 Lumbar Stenosis Outcomes Research (LUSTOR) Completed NCT00638443 Phase 4 Pregabalin;Diphenhydramine
41 Surgical Outcomes Using Variable Rod Diameters in the Treatment of Idiopathic Scoliosis Completed NCT00510575 Phase 4
42 Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery Completed NCT00508066 Phase 4 Bupivacaine;Normal Saline
43 Spine Research With Roentgen Stereophotogrammetric Analysis Completed NCT00493558 Phase 4
44 Effect of Nicardipine on Renal Function in Deliberate Hypotension Completed NCT02271191 Phase 4 Nicardipine
45 Analgetic and Anxiolytic Effect of Preoperative Pregabalin Completed NCT00353704 Phase 4 pregabalin;Placebo;morphine
46 Effects of Nonsteroidal Anti-inflammatory Drug (NSAID) on Inflammatory Lesion of Axial Spondyloarthritis Completed NCT03190603 Phase 4 Celecoxib
47 A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach Versus Routine Treatment Completed NCT02897115 Phase 4
48 Golimumab Versus Pamidronate for the Treatment of Axial Spondyloarthropathy: a 48-week Trial Completed NCT01718951 Phase 4 golimumab;Pamidronate
49 A Study to Evaluate the NSAIDS Sparing Effect of Etanercept in Subjects With Axial Spondyloarthritis Completed NCT01298531 Phase 4 etanercept;etanercept;placebo
50 Adalimumab in Axial Spondyloarthritis (ASIM) - MRI and Biomarkers in Patients With Spondyloarthritis Completed NCT01029847 Phase 4 Adalimumab;Placebo

Search NIH Clinical Center for Spinal Disease

Genetic Tests for Spinal Disease

Anatomical Context for Spinal Disease

MalaCards organs/tissues related to Spinal Disease:

41
Bone, Spinal Cord, Testes, Brain, Bone Marrow, Heart, Endothelial

Publications for Spinal Disease

Articles related to Spinal Disease:

(show all 35)
# Title Authors Year
1
The potential of minimally invasive surgery to treat metastatic spinal disease versus open surgery: a systematic review and meta-analysis. ( 29408300 )
2018
2
Epidemiology and national trends in prevalence and surgical management of metastatic spinal disease. ( 29681425 )
2018
3
Controversies in the differential diagnosis of Brown-Sequard syndrome due to cervical spinal disease from stroke: A case series. ( 28971161 )
2017
4
Modified Frailty Index and Body Mass Index as Predictors of Adverse Surgical Outcomes in Degenerative Spinal Disease. ( 29368317 )
2017
5
Correlation of Functional Outcomes and Sagittal Alignment after Long Instrumented Fusion for Degenerative Thoracolumbar Spinal Disease. ( 29077603 )
2017
6
Patient-perceived surgical indication influences patient expectations of surgery for degenerative spinal disease. ( 28359906 )
2017
7
Comparison of Outcomes of Anterior, Posterior, and Transforaminal Lumbar Interbody Fusion Surgery at a Single Lumbar Level with Degenerative Spinal Disease. ( 28189865 )
2017
8
Robotic versus fluoroscopy-guided pedicle screw insertion for metastatic spinal disease: a matched-cohort comparison. ( 28463620 )
2017
9
Feasibility of a Modified E-PASS and POSSUM System for Postoperative Risk Assessment in Patients with Spinal Disease. ( 29277590 )
2017
10
What Is the Role of Epidural Steroid Injections in Lumbar Spinal Disease with Moderate Disability? ( 27228516 )
2016
11
Spinal disease in myeloma: cohort analysis at a specialist spinal surgery centre indicates benefit of early surgical augmentation or bracing. ( 27401073 )
2016
12
Dynamic stabilization using the Dynesys system versus posterior lumbar interbody fusion for the treatment of degenerative lumbar spinal disease: a clinical and radiological outcomes-based meta-analysis. ( 26721581 )
2016
13
Surgical Outcome Predictor in Degenerative Lumbar Spinal Disease Based on Health Related Quality of Life Using Euro-Quality 5 Dimensions Analysis. ( 27401654 )
2016
14
Survival analysis in patients with metastatic spinal disease: the influence of surgery, histology, clinical and neurologic status. ( 25992524 )
2015
15
Lumbosacral Plexopathy Caused by Presacral Recurrence of Colon Cancer Mimicking Degenerative Spinal Disease: A Case Report. ( 26217393 )
2015
16
Clinical reasoning in canine spinal disease: what combination of clinical information is useful? ( 26198211 )
2015
17
Artificial disc and vertebra system: a novel motion preservation device for cervical spinal disease after vertebral corpectomy. ( 26222819 )
2015
18
Lumbar subcutaneous edema and degenerative spinal disease in patients with low back pain: a retrospective MRI study. ( 25904349 )
2015
19
Smoking is Associated with Poorer Quality-Based Outcomes in Patients Hospitalized with Spinal Disease. ( 26075207 )
2015
20
Microbiology and epidemiology of infectious spinal disease. ( 25289121 )
2014
21
Current paradigms for metastatic spinal disease: an evidence-based review. ( 24145995 )
2014
22
Spinal instability as defined by the spinal instability neoplastic score is associated with radiotherapy failure in metastatic spinal disease. ( 24704681 )
2014
23
Comparison of one versus two cages in lumbar interbody fusion for degenerative lumbar spinal disease: a meta-analysis. ( 25179359 )
2014
24
Not neural deformation or compression but instability is the cause of symptoms in degenerative spinal disease. ( 25558142 )
2014
25
Comparative efficacy of levobupivacaine and ropivacaine for epidural block in outpatients with degenerative spinal disease. ( 25415777 )
2014
26
Minimally invasive percutaneous fixation techniques for metastatic spinal disease. ( 25179352 )
2014
27
Tumor extravasation following a cement augmentation procedure for vertebral compression fracture in metastatic spinal disease. ( 24905395 )
2014
28
Quantification of vertebral involvement in metastatic spinal disease. ( 24015159 )
2013
29
Imaging spectrum of CNS coccidioidomycosis: prevalence and significance of concurrent brain and spinal disease. ( 23701073 )
2013
30
Expanding the spectrum of inflammatory spinal disease: AS it was, as it is now. ( 23873819 )
2013
31
Inflammatory spinal disease in psoriatic arthritis: a report from the GRAPPA 2010 annual meeting. ( 22298270 )
2012
32
Charcot spinal disease after spinal cord injury. ( 18976172 )
2008
33
Inflammatory biomarkers, disease activity and spinal disease measures in patients with ankylosing spondylitis after treatment with infliximab. ( 17644552 )
2008
34
[Therapeutic use of "biologics" in inflammatory joint and spinal diseases]. ( 12428439 )
2002
35
[Peroneal muscle atrophy with talipes cavus. Pyramidal symptoms and sensory disorders in one family. On the problem of the nosological classification of hereditary spinal diseases and polyneuropathies]. ( 2255880 )
1990

Variations for Spinal Disease

Expression for Spinal Disease

Search GEO for disease gene expression data for Spinal Disease.

Pathways for Spinal Disease

Pathways related to Spinal Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 IL6 VEGFA
2 10.84 IL6 VEGFA
3
Show member pathways
10.43 CRP VEGFA
4 9.9 CRP IL6

GO Terms for Spinal Disease

Cellular components related to Spinal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SMN-Sm protein complex GO:0034719 9.26 SMN1 SMN2
2 SMN complex GO:0032797 9.16 SMN1 SMN2
3 perikaryon GO:0043204 9.13 NAIP SMN1 SMN2
4 Gemini of coiled bodies GO:0097504 8.62 SMN1 SMN2

Biological processes related to Spinal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nervous system development GO:0007399 9.56 NAIP SMN1 SMN2 VEGFA
2 acute-phase response GO:0006953 9.4 CRP IL6
3 spliceosomal complex assembly GO:0000245 9.37 SMN1 SMN2
4 spliceosomal snRNP assembly GO:0000387 9.32 SMN1 SMN2
5 import into nucleus GO:0051170 9.16 SMN1 SMN2
6 DNA-templated transcription, termination GO:0006353 8.96 SMN1 SMN2
7 negative regulation of lipid storage GO:0010888 8.62 CRP IL6

Molecular functions related to Spinal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.02 CRP MRAP SMN1 SMN2 VEGFA

Sources for Spinal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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