Drugs for Spinal Muscular Atrophy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show top 50)
(show all 79)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Acetaminophen |
Approved |
Phase 4 |
|
103-90-2 |
1983 |
Synonyms:
4-(Acetylamino)phenol
4-Acetamidophenol
4-Acetaminophenol
4'-Hydroxyacetanilide
4-Hydroxyacetanilide
4-Hydroxyanilid kyseliny octove
A.F. anacin
ABDINE
Abenol
Abensanil
Abrol
Abrolet
Acamol
Accu-tap
Acenol
Acephen
Acertol
Aceta elixir
Aceta tablets
Acetaco
Acetagesic
Acetalgin
Acetamidophenol
Acetaminofen
ACETAMINOFÉN
ACETAMINOPHEN
Acetaminophen uniserts
acetaminophen|Panadol®|Tylenol®
Acetaminophene
ACÉTAMINOPHÈNE
Acetamol
Acetofen
Acetominophen
Actamin
Actamin extra
Actamin super
Actifed plus
Actimol
Actimol chewable tablets
Actimol children's suspension
Actimol infants' suspension
Actimol junior strength caplets
Actron
Afebrin
Afebryl
Aferadol
Algesidal
Algina
Algomol
Algotropyl
Allay
alpha-Per
Alpiny
Alpinyl
Alvedon
Amadil
Aminofen
Aminofen max
Anacin
Anacin 3
Anacin3
Anacin-3
Anacin-3 extra strength
Anadin dla dzieci
Anaflon
Analter
Anapap
Andox
Anelix
Anexsia
Anexsia 10/660
Anexsia 5/325
Anexsia 7.5/325
Anexsia 7.5/650
ANGIERS
Anhiba
Anoquan
Anti-algos
Antidol
Apacet
Apacet capsules
Apacet elixir
Apacet extra strength caplets
Apacet extra strength tablets
Apacet regular strength tablets
Apadon
Apamid
Apamide
APAP
a-Per
Apitrelal
Apo-acetaminophen
Arfen
Asetam
Asomal
Aspac
Aspirin free anacin maximum strength caplets
Aspirin free anacin maximum strength gel caplets
Aspirin free anacin maximum strength tablets
Aspirin-free anacin
Aspirin-free excedrin caplets
Asplin
Atasol
Atasol caplets
Atasol drops
Atasol forte caplets
Atasol forte tablets
Atasol oral solution
Atasol tablets
Atralidon
Babikan
Bacetamol
Bancap
Bancap HC
Banesin
Bayer Select
Bayer select allergy-sinus
Bayer select head cold
Bayer select headache pain
Bayer select maximum strength headache pain relief formula
Bayer select menstrual multi-symptom
Bayer select sinus pain relief
Benmyo
Ben-u-ron
Bickie-mol
Biocetamol
Bucet
Butalbital
Butapap
Cadafen
Calapol
Calmanticold
Calpol
CALPOL SIX PLUS
CALPOL SIX PLUS FASTMELTS
Capital with codeine
Captin
Causalon
Cefalex
Cetadol
CHILD LEMSIP
Children'S acetaminophen elixir drops
Children'S acetaminophen oral solution
Children'S tylenol chewable
Claradol codeine
Clixodyne
Codabrol
COD-Acamol forte
Codalgin
Codapane
Codicet
Codisal
Codisal forte
Codoliprane
Codral pain relief
Cofamol
CO-Gesic
Conacetol
Contac cough & sore throat formula
Contra-schmerz p
Coricidin
Coricidin D
Coricidin sinus
Cosutone
Croix blanche
CUPANOL
Cuponol
Curadon
Curpol
Custodial
DAFALGAN
Dapa
Dapa X-S
Darocet
Darvocet
Darvocet-N 50
Datril
Datril extra-strength
Daygrip
Demilets
Deminofen
Democyl
Demogripal
Desfebre
Dhamol
DHC Plus
Dial-a-gesic
Dial-alpha-gesic
Dimindol
Dirox
Disprol
DISPROL INFANT
DISPROL JNR
DISPROL PAED
Dolcor
Dolefin
Dolegrippin
Dolene ap-65
Dolgesic
Doliprane
Dolko
Dolofugin
Doloreduct
Dolorfug
Dolorol forte
Dolorstop
Dolotec
Dolprone
Dol-stop
Dorocoff
Dresan
Dristan cold no drowsiness
Dristancito
Drixoral Plus
Dularin
Duracetamol
Duradyne DHC
Durapan
Dymadon
Dymadon co
Dymadon forte
Dypap
Ecosetol
Elixodyne
Empracet
Endecon
Enelfa
Eneril
Esgic
Esgic-plus
Eu-med
Excedrin
Excedrin caplets
Excedrin extra strength caplets
Excipain
Exdol
Exdol strong
Fanalgic
Farmadol
Febranine
Febrectal
Febrectol
Febrex
Febricet
Febridol
Febrilix
Febrin
Febrinol
Febro-gesic
Febrolin
Femcet
Fendon
FENNINGS
Fensum
Fepanil
Feverall
Feverall junior strength
Feverall sprinkle caps junior strength
Fevor
Finimal
Finiweh
Fioricet
Fluparmol
Fortalidon p
Freka-cetamol
GALPAMOL
Gattaphen T
Gelocatil
Geluprane
Genapap
Genapap children's elixir
Genapap children's tablets
Genapap extra strength caplets
Genapap extra strength tablets
Genapap regular strength tablets
Genebs
Genebs extra strength caplets
Genebs regular strength tablets
Genebs X-tra
Geralgine-p
Gripin bebe
Grippostad
Gynospasmine
Hedex
Helon N
Homoolan
Hycomine compound
Hydrocet
Hydroxyacetanilide
Hy-phen
Ildamol
Inalgex
Infadrops
Infants' feverall
Influbene N
Injectapap
Intensin
Janupap
Junior disprol
JUNIOR PARAPAED
Kataprin
Kinder finimal
Korum
Kratofin simplex
Labamol
Lekadol
Lemgrip
Lemsip
Lestemp
Liquagesic
Liquigesic co
Liquiprin
Liquiprin children's elixir
Liquiprin infants" drops
Lonarid
Lonarid mono
Lorcet-HD
Lortab
Lupocet
Lyteca
Lyteca syrup
Magnidol
Malex N
Malgis
Malidens
MANDANOL
Maxadol
Medigesic plus
MEDINOL
MEDINOL FOR CHILDREN
MEDINOL OVER 6
Medinol paediatric
MEDINOL UNDER 6
MEDISED PLAIN
Medocodene
Melabon infantil
Mexalen
Midol maximum strength
Midol PM night time formula
Midol regular strength
Midol teen formula
Migraleve yellow
Minafen
Minoset
MIRADOL
Miralgin
Momentum
|
mono Praecimed
Multin
N-(4-Hydroxyphenyl)acetamide
N-(4-Hydroxyphenyl)acetanilide
N-Acetyl-4-aminophenol
N-Acetyl-p-aminophenol
Naldegesic
NAPA
Napafen
Napap
Naprinol
Nealgyl
Nebs
NeoCitran
Neodol
Neodolito
Neo-fepramol
Neopap
Neotrend
Neuridon
New cortal for children
NilnOcen
Nina
Nobedon
Nodolex
NO-Febril
Noral
Norcet
Norco
NSC-109028
NSC-3991
O-Acetaminophenol
OFIRMEV
Oltyl
Oralgan
Oraphen-PD
Ortensan
Oxycet
Oxycocet
Oxycodone 2.5/apap 500
Oxycodone 5/apap 500
p-(Acetylamino)phenol
Paceco
Pacemo
Pacemol
Pacet
p-Acetamidophenol
p-Acetaminophenol
p-Acetylaminophenol
Pacimol
Paedialgon
Paedol
Painex
Paldesic
Pamol
Panacete
Panadeine
Panadeine co
Panadiene
PANADO
Panado-co
Panado-co caplets
Panadol
PANADOL ACTIFAST
PANADOL ACTIFAST SOLB
PANADOL ADVAN
Panadol extra strength
PANADOL JNR
Panadol junior strength caplets
Panadol maximum strength caplets
Panadol maximum strength tablets
PANADOL OA
Panaleve
PANALEVE 6 PLUS
Panamax
Panasorb
Panasorbe
Panets
Panex
Panodil
Panofen
Pantalgin
Papa-Deine
Papa-deine #3
Papa-deine #4
Paracemol
Paracenol
Paracet
Paracetamol
PARACÉTAMOL
Paracetamol al
Paracetamol antipanin p
Paracetamol basics
Paracetamol BC
Paracetamol DC
Paracetamol dr. schmidgall
Paracetamol fecofar
Paracetamol genericon
Paracetamol hanseler
Paracetamol harkley
Paracetamol heumann
Paracetamol hexal
Paracetamol italfarmaco
Paracetamol nycomed
Paracetamol PB
Paracetamol raffo
Paracetamol ratiopharm
Paracetamol rosch
Paracetamol saar
Paracetamol smithkline beecham
Paracetamol stada
Paracetamol von CT
Paracetamol winthrop
Paracetamole
Paracetamolo
Paracetamolum
Paracetanol
Paracetol
Paracin
Paracod
Paracodol
Parador
Paradrops
Parakapton
Parake
Paralen
Paralief
Paralink
Paralyoc
PARAMIN
Paramol
Paramolan
Paranox
PARAPAED JNR
PARAPAED SIX PLUS
Parapan
Parasedol
Parasin
Paraspen
Para-suppo
Para-tabs
PARAVICT
Parcetol
Parelan
Parmol
Parogal
Paroma
Pasolind
Pasolind N
PCM Paracetamol lichtenstein
Pediapirin
Pediatrix
Pedric
Percocet
Percocet-5
Percocet-demi
Percogesic with codeine
Perdolan mono
PERFALGAN
Pe-tam
Phenaphen
Phenaphen caplets
Phenaphen w/codeine
Phendon
Phenipirin
Phogoglandin
Phrenilin
Phrenilin forte
P-HYDROXY-ACETANILID
p-Hydroxyacetanilide
p-Hydroxyphenolacetamide
Pinex
Piramin
Pirinasol
PLACIDEX
Plicet
Polmofen
Predimol
Predualito
Prestwick_13
Prodol
Prompt
Prontina
Propacet
Propacet 100
Proval #3
Puernol
Pulmofen
Pyregesic-C
Pyrigesic
Pyrinazine
Pyromed
Quiet world
Redutemp
Reliv
Remedol
Rhinex D-lay tablets
RIMADOL
Rivalgyl
Robigesic
Robitussin night relief
Rockamol plus
Rounox
Roxicet
Roxicet 5/500
Roxilox
RubieMol
Rubophen
Rupemol
Salzone
Sanicet
Sanicopyrine
Scanol
Scentalgyl
Scherzatabletten rezeptur 534
Schmerzex
Sedalito
Sedapap
Semolacin
Servigesic
Seskamol
Setakop
Setamol
Setol
Sifenol
Sinaspril
Sinedol
Sine-OFF sinus medicine caplets
Sinmol
Sinubid
SK-Apap
Snaplets-FR
Spalt fur die nacht
Spalt N
ST Joseph aspirin-free
ST Joseph aspirin-free for children
St. joseph cold tablets for children
St. joseph fever reducer
Stanback
Stopain
Sudafed severe cold formula
Sudafed sinus
Sunetheton
Supac
Supadol mono
Supofen
Suppap
Suppap-120
Suppap-325
Suppap-650
Supramol-m
Synalgos-DC-a
Tabalgin
Tachiprina
Talacen
Tapanol
Tapanol extra strength caplets
Tapanol extra strength tablets
Tapar
Tavist allergy/sinus/headache
Tazamol
Temlo
Tempanal
Tempra
Tempra caplets
Tempra chewable tablets
Tempra d.s
Tempra drops
Tempra syrup
Tencon
Termacet
Termalgin
Termalgine
Termofren
TheraFlu
Tibinide
Tibizide
Tiffy
Tisin
Tisiodrazida
Titralgan
TIXYMOL
Tizide
Tocris-1706
Toximer p
Tralgon
TRAMIL 500
Treupel mon
Treupel N
Treuphadol
Triad
Triaminic sore throat formula
Triaprin
Tricoton
Tussapap
Tycolet
TYL
Tylenol
Tylenol allergy sinus
Tylenol arthritis extended relief
Tylenol caplets
Tylenol children's chewable tablets
Tylenol children's elixir
Tylenol children's suspension liquid
Tylenol drops
Tylenol elixir
Tylenol extra strength adult liquid pain reliever
Tylenol extra strength caplets
Tylenol extra strength gelcaps
Tylenol extra strength tablets
Tylenol gelcaps
Tylenol infants drops
Tylenol infants" suspension drops
Tylenol junior strength caplets
Tylenol junior strength chewable tablets
Tylenol regular strength caplets
Tylenol regular strength tablets
Tylenol tablets
Tylex
Tylex CD
Tylol
Tylox
Tylox-325
Tymol
Ultracet
Upsanol
Utragin
Valadol
Valgesic
Valorin
Valorin extra
Vanquish
Veralgina
Vermidon
Verpol
Viclor richet
Vicodin
Vicodin es
Vicodin HP
Vips
Viruflu
Vivimed
Volpan
Wygesic
Zatinol
Zolben
|
|
2 |
|
Risdiplam |
Approved, Investigational |
Phase 4 |
|
1825352-65-5 |
118513932 |
Synonyms:
7-(4,7-Diazaspiro(2.5)oct-7-yl)-2-(2,8-dimethylimidazo(1,2-b)pyridazin-6-yl)-4H-pyrido(1,2-a)pyrimidin-4-one
7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one
Evrysdi
|
|
|
3 |
|
Antipyretics |
|
Phase 4 |
|
|
|
4 |
|
Immunologic Factors |
|
Phase 4 |
|
|
|
5 |
|
Vaccines |
|
Phase 4 |
|
|
|
6 |
|
Hydroxyurea |
Approved |
Phase 2, Phase 3 |
|
127-07-1 |
3657 |
Synonyms:
Biosupressin
Carbamohydroxamate
Carbamohydroxamic acid
Carbamohydroximate
Carbamohydroximic acid
Carbamohydroxyamic acid
Carbamoyl oxime
Carbamyl hydroxamate
Carbamyl hydroxamic acid
Droxia
Droxia®|Hydrea®|hydroxycarbamide|Siklos®|SQ-1089|Xromi®
Hidrix
Hidroxicarbamida
HU
Hydrea
Hydreia
Hydroxicarbamidum
Hydroxycarbamid
Hydroxycarbamide
Hydroxycarbamidum
|
Hydroxycarbamine
Hydroxyharnstoff
Hydroxylurea
HYDROXYUREA
Hydura
Hydurea
Idrossicarbamide
Idrossicarbamide [Dcit]
Litaler
Litalir
N-Carbamoylhydroxylamine
N-HYDROXYUREA
NSC-32065
Oncocarbide
Onco-Carbide
Oxyurea
SIKLOS
SQ-1089
Sterile Urea
Ureaphil
|
|
7 |
|
Dalfampridine |
Approved |
Phase 2, Phase 3 |
|
504-24-5 |
1727 |
Synonyms:
4-AMINOPYRIDINE
4-aminopyridine|4-AP|Ampyra®|EL-970
4-AP
4-PYRIDINAMINE
4-PYRIDYLAMINE
AMPYRA
AMPYRA EXTENDED RELEASE
AVITROL
DALFAMPRIDINE
EL-970
FAMPRIDINA
|
FAMPRIDINE
FAMPRIDINE-SR
FAMPRIDINUM
FAMPYRA
GAMMA-AMINOPYRIDINE
N07XX07
NEURELAN
NSC-15041
P-AMINOPYRIDINE
γ-Aminopyridine
|
|
8 |
|
Lactitol |
Approved, Investigational |
Phase 3 |
|
585-86-4 |
157355 |
Synonyms:
4-O-beta-D-Galactopyranosyl-D-glucitol
4-O-β-D-Galactopyranosyl-D-glucitol
D-Lactitol
Emportal
Importal
Lactitol
|
Lactitolum
Neda lactiv importal
Oponaf
Pizensy
WURCS=2.0/2,2,1/[H2122H][a2112h-1b_1-5]/1-2/a4-b1
|
|
9 |
|
Potassium Channel Blockers |
|
Phase 2, Phase 3 |
|
|
|
10 |
|
Immunoglobulins, Intravenous |
|
Phase 3 |
|
|
|
11 |
|
Immunoglobulins |
|
Phase 3 |
|
|
|
12 |
|
Immunoglobulin G |
|
Phase 3 |
|
|
|
13 |
|
Antibodies, Monoclonal |
|
Phase 3 |
|
|
|
14 |
|
Antibodies |
|
Phase 3 |
|
|
|
15 |
|
Leuprolide |
Approved, Investigational |
Phase 2 |
|
53714-56-0 |
657181 |
Synonyms:
(D-Leu(6),des-gly-NH2(10),pro-ethylamide(9))-gonadotropin-releasing hormone
ABBOTT-43818
ABBOTT-43818 FREE BASE
ABBOTT-43818|Fensolvi® (leuprolide acetate injectable suspension)|Lupron®|TAP-144
Acetate, leuprolide
CKD-841
Enantone
Leuprolide
Leuprolide acetate
Leuprolide monoacetate
Leuprolide, (DL-leu)-isomer
Leuprolide, (L-leu)-isomer
Leuprorelin
|
Leuprorelin acetate
Leuprorelina
Leuproreline
Leuprorelinum
L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide
Lupron
Monoacetate, leuprolide
NSC-377526
PGlu-his-TRP-ser-tyr-D-leu-leu-arg-pro-NHC2H5
PGlu-his-TRP-ser-tyr-D-leu-leu-arg-pro-nhet
TAP 144
TAP-144
TAP-144 FREE BASE
|
|
16 |
|
Testosterone |
Approved, Investigational |
Phase 2 |
|
58-22-0 |
5408 6013 |
Synonyms:
(+-)-8-ISO-TESTOSTERONE
(+-)-RETROTESTOSTERONE
(+)-TESTOSTERONE
(+-)-TESTOSTERONE
(17B)-17-HYDROXY-ANDROST-4-EN-3-ONE
(1S,2R,10R,11S,14S,15S)-14-HYDROXY-2,15-DIMETHYLTETRACYCLO[8.7.0.0^{2,7}.0^{11,15}]HEPTADEC-6-EN-5-ONE
13-ISO-TESTOSTERONE
17 beta Hydroxy 4 androsten 3 one
17 beta Hydroxy 8 alpha 4 androsten 3 one
17A-HYDROXY-(13A)-ANDROST-4-EN-3-ONE
17A-HYDROXY-13A-ANDROST-4-EN-3-ONE
17A-HYDROXY-14B-ANDROST-4-EN-3-ONE
17A-HYDROXY-ANDROST-4-EN-3-ONE
17-beta-Hydroxy-4-androsten-3-one
17BETA-HYDROXY-4-ANDROSTEN-3-ONE
17-beta-Hydroxy-8 alpha-4-androsten-3-one
17B-HYDROXY-(10A)-ANDROST-4-EN-3-ONE
17B-HYDROXY-(13A)-ANDROST-4-EN-3-ONE
17B-HYDROXY-(8A)-ANDROST-4-EN-3-ONE
17B-HYDROXY-(8A,10A)-ANDROST-4-EN-3-ONE
17B-HYDROXY-(9B)-ANDROST-4-EN-3-ONE
17B-HYDROXY-(9B,10A)-ANDROST-4-EN-3-ONE
17B-HYDROXY-13A-ANDROST-4-EN-3-ONE
17b-Hydroxy-4-androsten-3-one
17B-HYDROXY-8A-ANDROST-4-EN-3-ONE
17B-HYDROXY-ANDROST-4-EN-3-ON
17B-HYDROXYANDROST-4-EN-3-ONE
17B-HYDROXY-ANDROST-4-EN-3-ONE
17B-HYDROXYANDROST-4-ENE-3-ONE
17B-HYDROXY-D4-ANDROSTEN-3-ONE
17B-TESTOSTERONE
17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
17-HYDROXY-ANDROST-4-EN-3-ONE
17-HYDROXY-D4-ANDROSTEN-3-ONE
17Î’-hydroxy-4-androsten-3-one
4-ANDROSTEN-17BETA-OL-3-ONE
4-Androsten-17b-ol-3-one
4-ANDROSTEN-17Î’-OL-3-ONE
4-ANDROSTEN-3-ONE-17B-OL
8 Isotestosterone
8-Isotestosterone
8-ISO-TESTOSTERONE
9B,10A-TESTOSTERONE
9B-TESTOSTERONE
Andriol
Andro
Andro 100
Andro L.A. 200
ANDRODERM
Androderm®|Delatestryl®
ANDROGEL
ANDROGEL 1%
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
ANDROPATCH
Andropository 200
Androsorb
ANDROST-4-EN-17B-OL-3-ONE
ANDROST-4-ENE-17B-OL-3-ONE
Androtop
Andrusol
Andryl 200
AstraZeneca brand OF testosterone
Auxilium pharmaceuticals inc. brand OF testosterone
AXIRON
Bartor brand OF testosterone
Beta Testosterone
Bio-T-Gel
CDB 111C
CEPA brand OF testosterone
Cristerona T
Cristerone T
D4-ANDROSTEN-17B-OL-3-ONE
Dea No. 4000
Delatest
DELATESTRYL
Depotest
Depo-Testosterone
Depo-Testosterone Cypionate
Dr. kade brand OF testosterone
Epitestosteron
Everone 200
Faulding brand OF testosterone
Ferring brand OF testosterone
FORTESTA
Geno-cristaux gremy
GlaxoSmithKline brand OF testosterone
Hauck brand OF testosterone
Histerone
Homosteron
Homosterone
INTRINSA
Libigel
LUMITESTOSTERON
|
Malerone
Malestrone
Malogen in Oil
Malogen, Aquaspension Injection
MERTESTATE
Metandren
Methyltestosterone
NATESTO
Neo-Hombreol F
Neotestis
Neo-Testis
NSC-9700
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Ortho brand OF testosterone
Paladin brand OF testosterone
Pasadena brand OF testosterone
Perandren
Percutacrine androgenique
Primotest
Primoteston
RAC-17B-HYDROXY-(13A)ANDROST-4-EN-3-ONE
RAC-17B-HYDROXY-(8A)-ANDROST-4-EN-3-ONE
RAC-17B-HYDROXY-(9B,10A)ANDROST-4-EN-3-ONE
RAC-17B-HYDROXY-ANDROST-4-EN-3-ONE
Relibra
RETROTESTOSTERONE
Scheinpharm Testone-Cyp
Schering brand OF testosterone
SmithKline beecham brand OF testosterone
Solvay brand OF testosterone
Sterotate
STRIANT
STRIANT SR
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
TESTIM
TESTIM 1%
Testobase
TESTODERM
TESTODERM TTS
TESTOGEL
Testoject-50
Testolent
Testolin
TESTOPATCH
TESTOPEL
Testopel Pellets
Testopropon
TESTORAL
Testosteroid
TESTOSTERON
TESTOSTERONA
Testosterona [INN-Spanish]
TESTOSTERONE
TESTOSTÉRONE
TESTOSTERONE CIII
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone sulfate
TESTOSTERONUM
Testosteronum [INN-Latin]
Testostosterone
Testoviron
Testoviron schering
Testoviron T
Testred
Testred Cypionate 200
Testrin-P.A
Testro aq
TESTRONE
Testryl
TOSTRAN
Tostrelle
Tostrex
Trans-Testosterone
Ulmer brand OF testosterone
Unimed brand OF testosterone
Viatrel
Virilon
Virilon IM
Virormone
VIROSTERONE
VOGELXO
Watson brand OF testosterone
|
|
17 |
|
Levetiracetam |
Approved |
Phase 2 |
|
102767-28-2 |
441341 5284583 |
Synonyms:
AGB-101
alpha Ethyl 2 oxo 1 pyrrolidineacetamide
alpha-Ethyl-2-oxo-1-pyrrolidineacetamide
DESITREND
e Keppra
ELEPSIA XR
Etiracetam
Etiracetam, R isomer
Etiracetam, R-isomer
Etiracetam, S isomer
Etiracetam, S-isomer
Keppra
KEPPRA XR
Keppra®|Spritam®|UCB L059|UCB-L 059
LEVETIRACETAM
Levetiracetam [INN]
LEVETIRACETAM IN SODIUM CHLORIDE
|
Levetiracetame
Levetiracetamum
Levetiracetamum [INN-Latin]
Levitiracetam
MATEVER
N03AX14
R-Isomer etiracetam
S-Isomer etiracetam
SPRITAM
UCB brand OF levetiracetam
Ucb L059
Ucb L060
UCB-22059
Ucb-L059
UcbL060
Ucb-L060
|
|
18 |
|
Amifampridine |
Approved, Investigational |
Phase 2 |
|
54-96-6 |
5918 |
Synonyms:
3,4 Diaminopyridine
3,4-DAP
3,4-Diaminopyridine
3,4-DIAMMONIOPYRIDINIUM
3,4-Pyridinediamine
4,5-Diaminopyridine
4-DAP
Amifampridine
|
Amifampridine phosphate
DAP
Firdapse
NSC-521760
PYRIDINE-3,4-DIAMINE
Ruzurgi
ZENAS
|
|
19 |
|
Celecoxib |
Approved, Investigational |
Phase 2 |
|
169590-42-5 |
2662 |
Synonyms:
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENE-1-SULFONAMIDE
4-[5-(4-METHYLPHENYL)-3-TRIFLUOROMETHYL)-1H-PYRAZOL-YL]BENZENESULFONAMIDE
CELEBRA
Celebrex
CELECOX
Celecox®|Elyxyb® (DFN-15; oral solution)|Onsenal®|SC-58635|SC58635
Celecoxib
Célécoxib
|
Celecoxibum
Celocoxib
DFN15
DFN-15
Onsenal
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide
p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulphonamide
SC-58635
|
|
20 |
|
(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium |
Experimental |
Phase 2 |
|
461-06-3 |
|
Synonyms:
CARNITINE
CARNITINE CHLORIDE
|
|
|
21 |
|
Neurotransmitter Agents |
|
Phase 2 |
|
|
|
22 |
|
Anticonvulsants |
|
Phase 2 |
|
|
|
23 |
|
Bromides |
|
Phase 2 |
|
|
|
24 |
|
Pyridostigmine Bromide |
|
Phase 2 |
|
101-26-8 |
|
Synonyms:
KALYMIN
MESTINON
MESTINON 10
MESTINON RET
NSC-679759
|
PYRIDOSTIGMINE BROMIDE
REGONAL
REGONOL
RO-1-5130
|
|
25 |
|
Cholinesterase Inhibitors |
|
Phase 2 |
|
|
|
26 |
|
Cholinergic Agents |
|
Phase 2 |
|
|
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27 |
|
Hormone Antagonists |
|
Phase 2 |
|
|
|
28 |
|
Antineoplastic Agents, Hormonal |
|
Phase 2 |
|
|
|
29 |
|
Androgens |
|
Phase 2 |
|
|
|
30 |
|
Nootropic Agents |
|
Phase 2 |
|
|
|
31 |
|
Pharmaceutical Solutions |
|
Phase 2 |
|
|
|
32 |
|
4-phenylbutyric acid |
|
Phase 1, Phase 2 |
|
|
|
33 |
|
Analgesics |
|
Phase 2 |
|
|
|
34 |
|
Analgesics, Non-Narcotic |
|
Phase 2 |
|
|
|
35 |
|
Antirheumatic Agents |
|
Phase 2 |
|
|
|
36 |
|
Cyclooxygenase Inhibitors |
|
Phase 2 |
|
|
|
37 |
|
Cyclooxygenase 2 Inhibitors |
|
Phase 2 |
|
|
|
38 |
|
Anti-Inflammatory Agents, Non-Steroidal |
|
Phase 2 |
|
|
|
39 |
|
Anti-Inflammatory Agents |
|
Phase 2 |
|
|
|
40 |
|
Itraconazole |
Approved, Investigational |
Phase 1 |
|
84625-61-6 |
55283 |
Synonyms:
ITC
ITCZ
Itraconazol
ITRACONAZOLE
Itraconazole janssen brand
Itraconazolum
ITRAZOLE
Itrizole
ITZ
Janssen brand OF itraconazole
Janssen cilag brand OF itraconazole
|
Janssen-cilag brand OF itraconazole
ONMEL
Oriconazole
Orungal
R-51211
SPORANOS
Sporanox
SPORANOX I.V.
SPORANOX-PULSE
TOLSURA
|
|
41 |
|
Miconazole |
Approved, Investigational, Vet_approved |
Phase 1 |
|
22916-47-8 |
4189 |
Synonyms:
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
Brentan
CONOFITE
Dactarin
DERMAZOLE
DUMICOAT
Esteve brand OF miconazole
florid(nitrate)|Monistat®|R-14889
Janssen cilag brand OF miconazole
Janssen-cilag brand OF miconazole
Johnston and johnston brand OF miconazole nitrate
LORAMYC
MCZ
MICATIN
|
Miconasil nitrate
Miconazol
Miconazole
Miconazole esteve brand
Miconazole janssen-cilag brand
Miconazole nitrate
Miconazolum
Monistat
MONISTAT-3
MONISTAT-DERM
Nitrate, miconasil
Nitrate, miconazole
NSC-170986
Oravig
VUSION
|
|
42 |
|
Clotrimazole |
Approved, Vet_approved |
Phase 1 |
|
23593-75-1 |
2812 |
Synonyms:
(Chlorotrityl)imidazole
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole
1-(a-(2-Chlorophenyl)benzhydryl)imidazole
1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole
1-(O-Chloro-a,a-diphenylbenzyl)imidazole
1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole
1-(O-Chlorotrityl)imidazole
1-(O-Chloro-α,α-diphenylbenzyl)imidazole
1-(Α-(2-chlorophenyl)benzhydryl)imidazole
ABTRIM
ACTAVALL
Bay b 5097
BAY-5097
Bayer brand 1 OF clotrimazole
Bayer brand 2 OF clotrimazole
CANDIDEN
Canesten
Canesten 1-day cream combi-pak
Canesten 1-day therapy
Canesten 3-day therapy
Canesten 6-day therapy
CANESTEN AF
Canesten combi-pak 1-day therapy
Canesten combi-pak 3-day therapy
Canesten cream
CANESTEN CRM COMBI
CANESTEN INTERNAL
Canesten solution
CANESTEN VC
Canesten®|Lotrimin®
Canestine
Chlotrimazole
Clotrimaderm
Clotrimaderm cream
Clotrimazol
CLOTRIMAZOLE
Clotrimazole schering brand
Clotrimazolum
Desamix F
Empecid
FB b 5097
Fem care
FemCare
FUNGEDERM
GNF-PF-3499
Gyne lotrimin
Gyne-lotrimin
Gyne-lotrimin 3
Gyne-lotrimin 3 combination pack
Gyne-lotrimin combination pack
Gyne-lotrimin3
Gyne-lotrimin3 combination pack
|
Gynix
Kanesten
Klotrimazole
Lopac-C-6019
Lotrimax
Lotrimin
LOTRIMIN (TN)
Lotrimin af
Lotrimin af cream
Lotrimin af jock-itch cream
Lotrimin af lotion
Lotrimin af solution
Lotrimin cream
Lotrimin lotion
Lotrimin solution
Lotrisone
MASNODERM
mono-Baycuten
Monobaycuten
Mycelax
Mycelex
MYCELEX (TN)
Mycelex 7
Mycelex cream
Mycelex g
Mycelex otc
Mycelex solution
Mycelex troches
Mycelex twin pack
Mycelex: mycosporinrimazole
Mycelex-7
Mycelex-7 combination pack
Mycelex-g
MYCIL GOLD
Myclo cream
Myclo solution
Myclo spray solution
Myclo-gyne
Mycosporin
Mykosporin
Neo-zol cream
NSC-257473
Otomax
Pedisafe
Prestwick_120
PRIVACOM
Rimazole
Schering brand OF clotrimazole
Tibatin
Trimysten
Trivagizole 3
Veltrim
|
|
43 |
|
Midazolam |
Approved, Illicit |
Phase 1 |
|
59467-70-8 |
4192 |
Synonyms:
Buccolam
Buccolam®|Dormicum®|Nayzilam®|USL261 (nasal spray formulation)|Versed®
Dea no. 2884
Dormicum
Hydrochloride, midazolam
Maleate, midazolam
Mezolam
Midazolam
Midazolam base
MIDAZOLAM CIV
|
Midazolam Hcl
Midazolam hydrochloride
Midazolam maleate
Midazolamum
Midazolamum [INN-Latin]
Nayzilam
USL261
USL-261
Versed
|
|
44 |
|
Esomeprazole |
Approved, Investigational, Vet_approved |
Phase 1 |
|
73590-58-6, 119141-88-7 |
9568614 4594 |
Synonyms:
( -)-Omeprazole
(−)-omeprazole
(-)-Omeprazole
(S)-(−)-omeprazole
(S)-(-)-Omeprazole
(S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
(S)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
(S)-Omeprazole
(S)-omeprazole|Nexium®
2,3,5-Trimethylpyridine/Omeprazole
A02BC05
Alenia
Antra
Antra mups
AstraZeneca brand OF esomeprazole magnesium
Audazol
Aulcer
Axagon
Belmazol
Ceprandal
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
EMOZUL
Epirazole
Erbolin
Escz
Esofag
Esomeprazol
Esomeprazole
Ésoméprazole
Esomeprazole magnesium
Esomeprazole potassium
Esomeprazole sodium
Esomeprazole strontium
Esomeprazole strontium anhydrous
Esomeprazolum
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168/68
H 168/68|Losec®|Prilosec®
H-168/68
Indurgan
Inexium paranova
Inhibitron
Inhipump
Lensor
Logastric
Lomac
Losec
LOSEC MUPS
Lucen
Magnesium, omeprazole
Mepral
MEZZOPRAM
Miol
Miracid
Mopral
Morecon
Nexiam
Nexium
NEXIUM CONTROL
NEXIUM I.V.
Nexium IV
Nilsec
Nopramin
|
Nuclosina
Ocid
Olexin
Omapren
Omebeta 20
Omed
Omegast
OMEP
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole
Omeprazole magnesium
Omeprazole pellets
Omeprazole S-form
Omeprazole sodium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprol
OMERAN
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
OMP
Ompanyt
OMZ
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Perprazole
Prazentol
Prazidec
Prazolit
Prestwick_808
Prilosec
Prilosec otc
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
Sanamidol
Secrepina
Sodium, omeprazole
Strontium, esomeprazole
Tedec ulceral
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
VENTRA
Victrix
ZANPROL
Zefxon
Zegerid
Zepral
Zimor
Zoltum
|
|
45 |
|
Psychotropic Drugs |
|
Phase 1 |
|
|
|
46 |
|
Antifungal Agents |
|
Phase 1 |
|
|
|
47 |
|
Hydroxyitraconazole |
|
Phase 1 |
|
|
108222 |
Synonyms:
|
48 |
|
Cytochrome P-450 Enzyme Inhibitors |
|
Phase 1 |
|
|
|
49 |
|
Cytochrome P-450 CYP3A Inhibitors |
|
Phase 1 |
|
|
|
50 |
|
Anti-Anxiety Agents |
|
Phase 1 |
|
|
|
Interventional clinical trials:
(show top 50)
(show all 194)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy |
Unknown status |
NCT03648658 |
Phase 4 |
Paracetamol 120Mg/5mL Oral Suspension |
2 |
Comparison of the Immunogenicity of Intramuscular Versus Subcutaneous Administration of Trivalent Inactivated Influenza Vaccine in Individuals With Neuromuscular Diseases |
Completed |
NCT01422200 |
Phase 4 |
|
3 |
A Phase 4 Study of Nusinersen (BIIB058) Among Patients With Spinal Muscular Atrophy Who Received Onasemnogene Abeparvovec |
Recruiting |
NCT04488133 |
Phase 4 |
Nusinersen |
4 |
Long-Term Follow-Up Study of Patients With Spinal Muscular Atrophy Receiving Risdiplam Treatment |
Recruiting |
NCT05232929 |
Phase 4 |
Risdiplam |
5 |
A Phase IV Open-label, Single-arm, Single-dose, Multicenter Study to Evaluate the saFEty, toLerability and effIcacy of Gene Replacement Therapy With Intravenous OAV101 (AVXS-101) in Pediatric Patients From Latin America and Canada With Spinal Muscular Atrophy (SMA) - OFELIA |
Active, not recruiting |
NCT05073133 |
Phase 4 |
|
6 |
Risdiplam Exchange in Patients With Spinal Muscular Atrophy (SMA) Previously and Exclusively Treated With Nusinersen |
Not yet recruiting |
NCT05522361 |
Phase 4 |
Risdiplam |
7 |
Randomized Placebo Controlled Trial of Valproate and Levocarnitine in Children With Spinal Muscular Atrophy Aged 2-15 Years |
Unknown status |
NCT01671384 |
Phase 3 |
Valproate, Levocarnitine;Placebo |
8 |
A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Later-onset Spinal Muscular Atrophy |
Completed |
NCT02292537 |
Phase 3 |
Nusinersen |
9 |
Phase 3, Open-Label, Single-Arm, Single-Dose Gene Replacement Therapy Clinical Trial for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies Delivering AVXS-101 by Intravenous Infusion |
Completed |
NCT03306277 |
Phase 3 |
|
10 |
Phase 3, Open-Label, Single-Arm, Single-Dose Gene Replacement Therapy Clinical Trial for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies Delivering AVXS-101 by Intravenous Infusion |
Completed |
NCT03837184 |
Phase 3 |
|
11 |
A Randomized, Double-Blind, Placebo-Controlled Trial of Hydroxyurea in Spinal Muscular Atrophy |
Completed |
NCT00485511 |
Phase 2, Phase 3 |
Hydroxyurea |
12 |
A Global Study of a Single, One-Time Dose of AVXS-101 Delivered to Infants With Genetically Diagnosed and Pre-symptomatic Spinal Muscular Atrophy With Multiple Copies of SMN2 |
Completed |
NCT03505099 |
Phase 3 |
|
13 |
Phase 3, Open-Label, Single-Arm, Single-Dose Gene Replacement Therapy Clinical Trial for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies Delivering AVXS-101 by Intravenous Infusion |
Completed |
NCT03461289 |
Phase 3 |
|
14 |
Columbia SMA Project: 4-AP as a Potential SMA Therapeutic Agent and Biological Mechanisms of Action |
Completed |
NCT01645787 |
Phase 2, Phase 3 |
4-aminopyridine;Placebo |
15 |
Phase 3, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Apitegromab (SRK-015) in Patients With Later-Onset Spinal Muscular Atrophy Receiving Background Nusinersen or Risdiplam Therapy |
Recruiting |
NCT05156320 |
Phase 3 |
Apitegromab;Placebo |
16 |
A Phase 3b Study to Evaluate Higher Dose Nusinersen (BIIB058) in Patients With Spinal Muscular Atrophy Previously Treated With Risdiplam |
Recruiting |
NCT05067790 |
Phase 3 |
Nusinersen |
17 |
Escalating Dose and Randomized, Controlled Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy |
Recruiting |
NCT04089566 |
Phase 2, Phase 3 |
Nusinersen |
18 |
A Phase IIIb, Open-label, Single-arm, Single-dose, Multicenter Study to Evaluate the Safety, Tolerability and Efficacy of Gene Replacement Therapy With Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) |
Recruiting |
NCT04851873 |
Phase 3 |
|
19 |
A Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Ambulatory and Non-Ambulatory Participants With Spinal Muscular Atrophy With Open-Label Extension |
Recruiting |
NCT05337553 |
Phase 3 |
tadefgrobep alfa;Placebo |
20 |
A Two-Part, Seamless, Multi-Center, Randomized, Placebo-Controlled, Double-Blind Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Ambulant Patients With Spinal Muscular Atrophy |
Recruiting |
NCT05115110 |
Phase 2, Phase 3 |
RO7204239;Placebo;Risdiplam |
21 |
A Randomized, Sham-controlled, Double-blind Study to Evaluate the Efficacy and Safety of Intrathecal OAV101 in Type 2 Spinal Muscular Atrophy (SMA) Patients Who Are ≥ 2 to < 18 Years of Age, Treatment Naive, Sitting, and Never Ambulatory |
Recruiting |
NCT05089656 |
Phase 3 |
|
22 |
A Long-term Follow-up Study of Patients in the Clinical Trials for Spinal Muscular Atrophy Receiving AVXS-101 |
Active, not recruiting |
NCT04042025 |
Phase 3 |
|
23 |
An Open-Label Extension Study for Patients With Spinal Muscular Atrophy Who Previously Participated in Investigational Studies of ISIS 396443 |
Active, not recruiting |
NCT02594124 |
Phase 3 |
nusinersen |
24 |
A Two Part Seamless, Open-label, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Infants With Type 1 Spinal Muscular Atrophy |
Active, not recruiting |
NCT02913482 |
Phase 2, Phase 3 |
Risdiplam |
25 |
A Two Part Seamless, Multi-Center Randomized, Placebo-Controlled, Double-Blind Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy Patients |
Active, not recruiting |
NCT02908685 |
Phase 2, Phase 3 |
Placebo;Risdiplam |
26 |
A Long-Term Extension Study of Nusinersen (BIIB058) Administered at Higher Doses in Participants With Spinal Muscular Atrophy Who Previously Participated in an Investigational Study With Nusinersen |
Enrolling by invitation |
NCT04729907 |
Phase 3 |
Nusinersen |
27 |
An Open-Label, Multicenter, Extension Trial to Evaluate the Long-Term Safety and Efficacy of Apitegromab in Patients With Type 2 and Type 3 Spinal Muscular Atrophy Who Completed Previous Investigational Trials of Apitegromab |
Not yet recruiting |
NCT05626855 |
Phase 3 |
Apitegromab |
28 |
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 IT or OAV101 IV in Clinical Trials |
Not yet recruiting |
NCT05335876 |
Phase 3 |
|
29 |
Phase IIIb, Open-label, Single-arm, Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally (1.2 x 10^14 Vector Genomes) to Participants 2 to 12 Years of Age With Spinal Muscular Atrophy (SMA) Who Have Discontinued Treatment With Nusinersen (Spinraza®) or Risdiplam (Evrysdi®) |
Not yet recruiting |
NCT05386680 |
Phase 3 |
|
30 |
A Phase 3, Randomized, Double-Blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Infantile-onset Spinal Muscular Atrophy |
Terminated |
NCT02193074 |
Phase 3 |
nusinersen |
31 |
Safety and Efficacy Study of Anti-cholinesterase Therapy on the Motor Functions in Patients With Spinal Muscular Atrophy Type 3. |
Unknown status |
NCT02227823 |
Phase 2 |
Pyridostigmine Bromide |
32 |
The Effectiveness of Allogeneic Adipose Derived Mesenchymal Stem Cells (ADMSCs) in the Phenotypic Changes of Werdnig Hoffman Patients |
Unknown status |
NCT02855112 |
Phase 1, Phase 2 |
|
33 |
Autologous Purified Bone-Marrow-Derived Stem Cell Therapy for Motor Neuron Disease |
Unknown status |
NCT03067857 |
Phase 1, Phase 2 |
|
34 |
Phase II, Multicenter, Randomized, Adaptive, Double-blind, Placebo Controlled Study to Assess Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Year Old Spinal Muscular Atrophy (SMA) Patients. |
Completed |
NCT01302600 |
Phase 2 |
Olesoxime;Placebo |
35 |
Multicenter, Open-Label, Single-Arm Study to Evaluate Long-Term Safety, Tolerability, and Effectiveness of 10 mg/kg BID Olesoxime in Patients With Spinal Muscular Atrophy |
Completed |
NCT02628743 |
Phase 2 |
Olesoxime |
36 |
Prospective Controlled Trial of Valproic Acid in Ambulant Adults With Spinal Muscular Atrophy (VALIANTSMA) Study |
Completed |
NCT00481013 |
Phase 2 |
Valproic Acid (VPA);Placebo |
37 |
Phase I/II Trial of Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy Type I (CARNI-VAL Type I) |
Completed |
NCT00661453 |
Phase 1, Phase 2 |
Valproic Acid and Levocarnitine |
38 |
A Randomized, Placebo-Controlled, Crossover Study to Evaluate the Safety and Efficacy of Amifampridine Phosphate in Ambulatory Patients With Spinal Muscular Atrophy (SMA) Type 3 |
Completed |
NCT03781479 |
Phase 2 |
Amifampridine Phosphate;Placebo Oral Tablet |
39 |
Prospective Phase I/II Study to Evaluate Effects of Sodium Phenylbutyrate in Pre-symptomatic Infants With Spinal Muscular Atrophy |
Completed |
NCT00528268 |
Phase 1, Phase 2 |
Sodium phenylbutyrate (NaPB) |
40 |
Can Treatment With Human Growth Hormone Increase Strength in Spinal Muscular Atrophy Type II and III? |
Completed |
NCT00533221 |
Phase 2 |
somatotropin;Placebo |
41 |
A Study to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of ISIS 396443 Delivered Intrathecally to Patients With Infantile-Onset Spinal Muscular Atrophy |
Completed |
NCT01839656 |
Phase 2 |
nusinersen |
42 |
A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Multiple Dose Study of CK-2127107 in Two Ascending Dose Cohorts of Patients With Spinal Muscular Atrophy |
Completed |
NCT02644668 |
Phase 2 |
Placebo;Reldesemtiv 150 mg;Reldesemtiv 450 mg |
43 |
An Open-Label, Dose Escalation Study to Assess the Safety, Tolerability and Dose-Range Finding of Multiple Doses of ISIS 396443 Delivered Intrathecally to Patients With Spinal Muscular Atrophy |
Completed |
NCT01703988 |
Phase 1, Phase 2 |
Nusinersen |
44 |
A Pilot Therapeutic Trial Using Hydroxyurea in Type II and Type III Spinal Muscular Atrophy Patients |
Completed |
NCT00568802 |
Phase 1, Phase 2 |
Hydroxyurea;Placebo to match hydroxyurea |
45 |
A Pilot Therapeutic Trial Using Hydroxyurea in Type I Spinal Muscular Atrophy Patients |
Completed |
NCT00568698 |
Phase 1, Phase 2 |
Hydroxyurea;Placebo to match hydroxyurea |
46 |
Multi-center Phase II Trial of Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy (SMA CARNI-VAL Trial) |
Completed |
NCT00227266 |
Phase 2 |
Valproic Acid and Levocarnitine;Placebo |
47 |
A Phase II, Mono-center, Placebo-controlled, Double-blind, Crossover Trial to Investigate Effect and Efficacy of Pyridostigmine in Dutch Patients With Spinal Muscular Atrophy Types 2, 3 and 4 |
Completed |
NCT02941328 |
Phase 2 |
Pyridostigmine;Placebo |
48 |
Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease |
Completed |
NCT00004771 |
Phase 2 |
leuprolide;testosterone |
49 |
Effects of Power Mobility on the Development and Function of Young Children With Severe Motor Impairments |
Completed |
NCT01028833 |
Phase 2 |
|
50 |
A Pilot Trial of Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease |
Completed |
NCT00324454 |
Phase 2 |
|
Cell-based therapeutics:
Data from LifeMap, the Embryonic Development and Stem Cells Database
Stem-cell-based therapeutic approaches for Spinal Muscular Atrophy:
Embryonic/Adult Cultured Cells Related to Spinal Muscular Atrophy:
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