MCID: SPN092
MIFTS: 19

Spinal Shock

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Spinal Shock

MalaCards integrated aliases for Spinal Shock:

Name: Spinal Shock 52

Classifications:



Summaries for Spinal Shock

MalaCards based summary : Spinal Shock is related to spinal cord injury and spasticity. The drugs Prednisolone phosphate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and colon.

Wikipedia : 74 Spinal shock was first defined by Whytt in 1750 as a loss of sensation accompanied by motor paralysis... more...

Related Diseases for Spinal Shock

Diseases related to Spinal Shock via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 spinal cord injury 10.3
2 spasticity 10.1
3 resting heart rate, variation in 9.7
4 heart disease 9.7
5 neurogenic bladder 9.7
6 quadriplegia 9.7
7 spinal cord disease 9.7
8 congestive heart failure 9.7
9 paraplegia 9.7
10 peroneal nerve paralysis 9.7
11 diabetes insipidus 9.7
12 hypoglycemia 9.7
13 fibrocartilaginous embolism 9.7
14 spastic paraparesis 9.7

Graphical network of the top 20 diseases related to Spinal Shock:



Diseases related to Spinal Shock

Symptoms & Phenotypes for Spinal Shock

Drugs & Therapeutics for Spinal Shock

Drugs for Spinal Shock (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
2
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
3
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
4
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
5 Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
6
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
7 Gastrointestinal Agents Phase 3
8 Methylprednisolone Acetate Phase 3
9 Antineoplastic Agents, Hormonal Phase 3
10 Hematinics Phase 3
11 Hormones Phase 3
12 Neuroprotective Agents Phase 3
13 Antiemetics Phase 3
14 Hormone Antagonists Phase 3
15 Epoetin alfa Phase 3 113427-24-0
16 Protective Agents Phase 3
17 glucocorticoids Phase 3
18 Anti-Inflammatory Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of the Tolerability and Efficacy of Erythropoietin (EPO) Treatment in Spinal Shock: Comparative Study VS Methylprednisolone (MP) Terminated NCT00561067 Phase 3 Erythropoietin;Methylprednisolone
2 Therapeutic Effects of Early and Late Onset Peripheral Pudendal Neurostimulation on Bladder Function and Autonomic Neuroplasticity in SCI - a Controlled European Multicenter Study Withdrawn NCT01043848

Search NIH Clinical Center for Spinal Shock

Genetic Tests for Spinal Shock

Anatomical Context for Spinal Shock

MalaCards organs/tissues related to Spinal Shock:

40
Spinal Cord, Brain, Colon, Lung, Testes, Bone, Heart

Publications for Spinal Shock

Articles related to Spinal Shock:

(show top 50) (show all 311)
# Title Authors PMID Year
1
Rapid motor cortical reorganization following subacute spinal cord dysfunction. 61
32289708 2020
2
Midsagittal tissue bridges are associated with walking ability in incomplete spinal cord injury: A magnetic resonance imaging case series. 61
30346248 2020
3
[Neurophysiological methods for predicting outcome in cases of spine and spinal cord injury]. 61
32412199 2020
4
Predictors of urinary or fecal incontinence in dogs with thoracolumbar acute non-compressive nucleus pulposus extrusion. 61
31674064 2019
5
Cervical epidural hematoma after spinal manipulation therapy: a case report. 61
31638954 2019
6
Effects of early intravesical administration of resiniferatoxin to spinal cord-injured rats in neurogenic detrusor overactivity. 61
31180583 2019
7
Vasopressor support in managing acute spinal cord injury: current knowledge. 61
28252264 2019
8
Gunshot Acquired Spinal Cord Injury in Civilians. 61
30649823 2019
9
Combined tracheostomy and thyroidectomy in a patient with cervical spine fracture. 61
31193797 2019
10
Revisit Spinal Shock: Pattern of Reflex Evolution during Spinal Shock. 61
30402418 2018
11
Early Systemic Alterations in Severe Spinal Cord Injury: An Experimental Study on the Impact of Injury Level on Renal Function. 61
29985870 2018
12
Alterations in cardiac autonomic control in spinal cord injury. 61
28228335 2018
13
Male Incontinence: The Etiology or Basis of Treatment. 61
29249687 2017
14
Inadvertent Intrathecal Administration of Local Anesthetics Leading to Spinal Paralysis with Lipid Emulsion Rescue. 61
29849393 2017
15
Analysis of complications following posterior vertebral column resection for the treatment of severe angular kyphosis greater than 100°. 61
28526568 2017
16
Extracorporeal lung support in patients with spinal cord injury: Single center experience. 61
27077571 2017
17
Myelopathy: chameleons and mimics. 61
27872169 2017
18
Is neck massage safe? A rare case of tetraplegia and spinal shock after neck manipulation. 61
28228050 2017
19
Prolonged bradycardia, asystole and outcome of high spinal cord injury patients: Risk factors and management. 61
27695550 2016
20
Conus medullaris stroke. Does F wave predict return of ambulation? 61
27356660 2016
21
Chronic Myeloid Leukemia with Extramedullary Blast Crisis: Two Unusual Sites with Review of Literature. 61
27408365 2016
22
Use of enteral salbutamol in spinal shock. 61
26748957 2016
23
Ultrasonic measurement of rectal diameter and area in neurogenic bowel with spinal cord injury. 61
25432419 2016
24
Prevalence, clinical presentation, prognosis, and outcome of 17 dogs with spinal shock and acute thoracolumbar spinal cord disease. 61
26676985 2016
25
Acute transverse myelitis in childhood: A single centre experience from North India. 61
26924166 2016
26
Bladder response to acute sacral neuromodulation while treating rats in different phases of complete spinal cord injury: a preliminary study. 61
26742980 2015
27
Effect of Alpha-1-Adrenergic Agonist, Midodrine for the Management of Long-Standing Neurogenic Shock in Patient with Cervical Spinal Cord Injury: A Case Report. 61
27169082 2015
28
Biomarkers of spinal cord injury and ensuing bladder dysfunction. 61
25446137 2015
29
The role of brain-derived neurotrophic factor (BDNF) in the development of neurogenic detrusor overactivity (NDO). 61
25653370 2015
30
Sexuality and sexual dysfunction in spinal cord-injured men in Turkey. 61
26422842 2015
31
Spinal shock. Assessment & treatment of spinal cord injuries & neurogenic shock. 61
25630163 2014
32
Neurogenic lower urinary tract dysfunction: how, when, and with which patients do we use urodynamics? 61
25063601 2014
33
Lower motor neuron paralysis with extensive cord atrophy in parainfectious acute transverse myelitis. 61
25221410 2014
34
Iatrogenic risks and maternal health: Issues and outcomes. 61
24639842 2014
35
Effects of reversible spinalization on individual spinal neurons. 61
24285903 2013
36
Acute hydrocephalus following cervical spinal cord injury. 61
24175033 2013
37
Changes in renal function during acute spinal cord injury: implications for pharmacotherapy. 61
23608810 2013
38
[Traumatic neurogenic shock]. 61
23566590 2013
39
Lower motor neuron findings after upper motor neuron injury: insights from postoperative supplementary motor area syndrome. 61
23508473 2013
40
Control and role of plateau potential properties in the spinal cord. 61
23360269 2013
41
A, B, C, D, echo: limited transthoracic echocardiogram is a useful tool to guide therapy for hypotension in the trauma bay--a pilot study. 61
23271097 2013
42
Exercise pressor reflex function following acute hemi-section of the spinal cord in cats. 61
23403764 2013
43
[Unconventional treatment procedures of the bladder in paraplegia and myelomeningocele]. 61
23160608 2012
44
Remarkable recovery in an infant presenting with extensive perinatal cervical cord injury. 61
23230249 2012
45
The timing of established detrusor hyperreflexia in a rat model of neuropathic bladder. 61
22883436 2012
46
Comprehensive locomotor outcomes correlate to hyperacute diffusion tensor measures after spinal cord injury in the adult rat. 61
22119625 2012
47
Post meningocele repair urinary ascites in a neonate--a rare presentation. 61
22595607 2012
48
Central nervous system regeneration does not occur. 61
22105462 2012
49
Clean intermittent self-catheterization in neuro-urology. 61
22222962 2011
50
Management of detrusor external sphincter dyssynergia in neurogenic bladder. 61
22081065 2011

Variations for Spinal Shock

Expression for Spinal Shock

Search GEO for disease gene expression data for Spinal Shock.

Pathways for Spinal Shock

GO Terms for Spinal Shock

Sources for Spinal Shock

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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