SCH
MCID: SPN012
MIFTS: 37

Spindle Cell Hemangioma (SCH)

Categories: Cancer diseases, Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Spindle Cell Hemangioma

MalaCards integrated aliases for Spindle Cell Hemangioma:

Name: Spindle Cell Hemangioma 12 60 15 74
Sch 12 77 17
Spindle Cell Hemangioendothelioma 60

Classifications:



External Ids:

Disease Ontology 12 DOID:496
NCIt 51 C4754
ICD10 via Orphanet 35 D18.0
UMLS via Orphanet 75 C1304508
Orphanet 60 ORPHA210584
UMLS 74 C1304508

Summaries for Spindle Cell Hemangioma

MalaCards based summary : Spindle Cell Hemangioma, also known as sch, is related to multiple enchondromatosis, maffucci type and enchondroma. An important gene associated with Spindle Cell Hemangioma is IDH1 (Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic), and among its related pathways/superpathways are Peroxisome and Cytosine methylation. Affiliated tissues include brain, testes and cortex.

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Related Diseases for Spindle Cell Hemangioma

Diseases related to Spindle Cell Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 multiple enchondromatosis, maffucci type 30.6 IDH1 IDH2
2 enchondroma 30.3 IDH1 IDH2
3 enchondromatosis, multiple, ollier type 30.1 IDH1 IDH2
4 hemangioendothelioma 11.6
5 hemangioma 10.6
6 interval angle-closure glaucoma 10.3 IDH1 IDH2
7 adult oligodendroglioma 10.3 IDH1 IDH2
8 intracranial chondrosarcoma 10.3 IDH1 IDH2
9 cytogenetically normal acute myeloid leukemia 10.3 IDH1 IDH2
10 chondroblastic osteosarcoma 10.3 IDH1 IDH2
11 intraductal papilloma 10.3 IDH1 IDH2
12 pilocytic astrocytoma of cerebellum 10.3 IDH1 IDH2
13 hepatitis c virus 10.3
14 hepatitis 10.3
15 hepatitis c 10.3
16 periosteal chondrosarcoma 10.3 IDH1 IDH2
17 glioma susceptibility 1 10.2 IDH1 IDH2
18 adult astrocytic tumour 10.2 IDH1 IDH2
19 fibrillary astrocytoma 10.2 IDH1 IDH2
20 diffuse infiltrative lymphocytosis syndrome 10.2 IDH1 IDH2
21 drug-induced mental disorder 10.2 IDH1 IDH2
22 drug psychosis 10.2 IDH1 IDH2
23 undifferentiated pleomorphic sarcoma 10.2 IDH1 IDH2
24 2-hydroxyglutaric aciduria 10.2 IDH1 IDH2
25 d-2-hydroxyglutaric aciduria 1 10.2 IDH1 IDH2
26 bile duct adenocarcinoma 10.2 IDH1 IDH2
27 asthma 10.2
28 noonan syndrome 3 10.2
29 brain stem glioma 10.1 IDH1 IDH2
30 angiosarcoma 10.1
31 supratentorial cancer 10.1 IDH1 IDH2
32 schizophrenia 10.1
33 hypothyroidism 10.1
34 cerebrum cancer 10.1 IDH1 IDH2
35 depression 10.1
36 central nervous system cancer 10.1 IDH1 IDH2
37 blastomycosis 10.0
38 ischemia 10.0
39 bronchitis 10.0
40 meningitis 10.0
41 nervous system cancer 10.0 IDH1 IDH2
42 arteriovenous malformation 10.0
43 cavernous hemangioma 10.0
44 colorectal cancer 10.0
45 hypertension, essential 10.0
46 allergic rhinitis 10.0
47 aspergillosis 10.0
48 leukemia 10.0
49 lymphedema 9.9
50 epithelioid hemangioendothelioma 9.9

Graphical network of the top 20 diseases related to Spindle Cell Hemangioma:



Diseases related to Spindle Cell Hemangioma

Symptoms & Phenotypes for Spindle Cell Hemangioma

Drugs & Therapeutics for Spindle Cell Hemangioma

Search Clinical Trials , NIH Clinical Center for Spindle Cell Hemangioma

Genetic Tests for Spindle Cell Hemangioma

Anatomical Context for Spindle Cell Hemangioma

MalaCards organs/tissues related to Spindle Cell Hemangioma:

42
Brain, Testes, Cortex, Prefrontal Cortex, Retina, Kidney, Pituitary

Publications for Spindle Cell Hemangioma

Articles related to Spindle Cell Hemangioma:

(show top 50) (show all 1100)
# Title Authors Year
1
Spindle cell hemangioma of the spleen: A case report. ( 30817572 )
2019
2
Relation of Different Components of Climate with Human Pituitary-Thyroid Axis and FT3/FT4 Ratio: A Study on Euthyroid and SCH Subjects in Two Different Seasons. ( 30800161 )
2019
3
Spindle Cell Hemangioma in the Mucosa of the Upper Lip: A Case Report and Review of the Literature. ( 29780644 )
2018
4
Expression and Clinical Significance of Serum 25-OH-D in pregnant women with SCH (Subclinical Hypothyroidism) and GDM (Gestational Diabetes Mellitus). ( 30344591 )
2018
5
Chk1 inhibitor SCH 900776 enhances the antitumor activity of MLN4924 on pancreatic cancer. ( 29157102 )
2018
6
MELD-SCH: A megastudy of lexical decision in simplified Chinese. ( 28779457 )
2018
7
Toxic effects of Solanum xanthocarpum Sch &Wendle against Helicoverpa armigera (Hub.), Culex quinquefasciatus (Say.) and Eisenia fetida (Savigny, 1826). ( 29143256 )
2018
8
Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in Vitro Antitrypanosomal Activity. ( 29382040 )
2018
9
Synthesis of 3 H, 13 C2 , 2 H414 C-SCH 430765 and 35 S-SCH 500946, potent and selective inhibitors of the NPY5 receptor. ( 29493011 )
2018
10
Chemical diversity of the essential oils of twenty populations of Tanacetum polycephalum Sch. Bip. from Iran. ( 29768020 )
2018
11
CYP2D6 Allelic Variants *34, *17-2, *17-3, and *53 and a Thr309Ala Mutant Display Altered Kinetics and NADPH Coupling in Metabolism of Bufuralol and Dextromethorphan and Altered Susceptibility to Inactivation by SCH 66712. ( 29784728 )
2018
12
New Poisson-Sch type inequalities and their applications in quantum calculus. ( 30137887 )
2018
13
SCH-GAN: Semi-Supervised Cross-Modal Hashing by Generative Adversarial Network. ( 30273169 )
2018
14
Main Allelochemicals from the Rhizosphere Soil of Saussurea lappa (Decne.) Sch. Bip. and Their Effects on Plants' Antioxidase Systems. ( 30274332 )
2018
15
Pharmacological study of anti-inflammatory activity of aqueous extracts of Mikania glomerata (Spreng.) and Mikania laevigata (Sch. Bip. ex Baker). ( 30415057 )
2018
16
Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D1 receptor antagonist SCH-23390 or the serotonin 5-HT2C agonist lorcaserin. ( 30419272 )
2018
17
Endophytic Fungus Isolated From Achyrocline satureioides Exhibits Selective Antiglioma Activity-The Role of Sch-642305. ( 30420941 )
2018
18
Characterization of polycyclic aromatic hydrocarbons (PAHs) in small craft harbour (SCH) sediments in Nova Scotia, Canada. ( 30503437 )
2018
19
Evaluation of anti-HSV-1 activity and toxicity of hydroethanolic extract of Tanacetum parthenium (L.) Sch.Bip. (Asteraceae). ( 30668436 )
2018
20
Spindle Cell Hemangioma of the Midfoot: A Case Report. ( 29242801 )
2017
21
Effect of Thyroxin Treatment on Carotid Intima-Media Thickness (CIMT) Reduction in Patients with Subclinical Hypothyroidism (SCH): a Meta-Analysis of Clinical Trials. ( 28566564 )
2017
22
SEM studies on acanthocephalan parasite, Echinorhynchus veli infecting the fish Synaptura orientalis (Bl & Sch, 1801). ( 28316390 )
2017
23
A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma. ( 27768921 )
2017
24
Structural Determination of (-)-SCH 64874 and Hirsutellomycin by Semisynthesis. ( 27966974 )
2017
25
Reliability of volumetric and surface-based normalisation and smoothing techniques for PET analysis of the cortex: A test-retest analysis using [11C]SCH-23390. ( 28419852 )
2017
26
Further result on Dirichlet-Sch type inequality and its application. ( 28546734 )
2017
27
Phytotoxicity Study on Bidens sulphurea Sch. Bip. as a Preliminary Approach for Weed Control. ( 28605187 )
2017
28
EPICOG-SCH: A brief battery to screen cognitive impact of schizophrenia in stable outpatients. ( 28740826 )
2017
29
Selective A2A receptor antagonist SCH 58261 modulates striatal oxidative stress and alleviates toxicity induced by 3-Nitropropionic acid in male Wistar rats. ( 28795281 )
2017
30
An Assessment of Five (PANSS, SAPS, SANS, NSA-16, CGI-SCH) commonly used Symptoms Rating Scales in Schizophrenia and Comparison to Newer Scales (CAINS, BNSS). ( 29430333 )
2017
31
Multifocal spindle cell hemangioma: Report of two cases. ( 26728826 )
2016
32
Intramedullary spindle cell hemangioma: case report. ( 27058496 )
2016
33
Spindle cell hemangioma in an elderly patient: Uncommon benign vascular neoplasm. ( 26945705 )
2016
34
A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcoma. ( 27362300 )
2016
35
Chemical composition of the essential oil from Pulicaria vulgaris var. graeca (Sch.-Bip.) Fiori (Asteraceae) growing wild in Sicily and its antimicrobial activity. ( 26180932 )
2016
36
Timing of SCH 23390 administration influences extinction of conditioned hyperactivity in mice. ( 26292185 )
2016
37
First Total Synthesis of Gliomasolide C and Formal Total Synthesis of Sch-725674. ( 26633579 )
2016
38
Hypotensive and antihypertensive effects of a hydroalcoholic extract from Senecio nutans Sch. Bip. (Compositae) in mice: Chronotropic and negative inotropic effect, a nifedipine-like action. ( 26724424 )
2016
39
A Pot-Economical Approach to the Total Synthesis of Sch-725674. ( 26760683 )
2016
40
Differential effects of co-administration of oxotremorine with SCH 23390 on impulsive choice in high-impulsive rats and low-impulsive rats. ( 26772787 )
2016
41
Identification of the Fluvirucin B2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadura fulva subsp. indica ATCC 53714: substrate Specificity of the β-Amino Acid Selective Adenylating Enzyme FlvN. ( 26818633 )
2016
42
Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones reduce oxidative damage in ultraviolet B-irradiated HaCaT cells via a p38MAPK-independent mechanism. ( 26855564 )
2016
43
Synthesis of (3) H, (2) H4 and (14) C-SCH 417690 (Vicriviroc). ( 26991320 )
2016
44
Systemic injection of the DAD1 antagonist SCH 23390 reduces saccharin seeking in rats. ( 27179937 )
2016
45
Total Synthesis of (+)-SCH 351448: Efficiency via Chemoselectivity and Redox-Economy Powered by Metal Catalysis. ( 27337561 )
2016
46
Hydroalcoholic extract and pure compounds from Senecio nutans Sch. Bip (Compositae) induce vasodilation in rat aorta through endothelium-dependent and independent mechanisms. ( 27392595 )
2016
47
Inhibitory effects of Saussurea involucrata (Kar. et Kir.) Sch. -Bip. on adjuvant arthritis in rats. ( 27616030 )
2016
48
Regio- and Stereoselective Homologation of 1,2-Bis(Boronic Esters): Stereocontrolled Synthesis of 1,3-Diols and Sch 725674. ( 27781356 )
2016
49
Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors. ( 27836402 )
2016
50
SCH 79797, a selective PAR1 antagonist, protects against ischemia/reperfusion-induced arrhythmias in the rat hearts. ( 27906419 )
2016

Variations for Spindle Cell Hemangioma

Expression for Spindle Cell Hemangioma

Search GEO for disease gene expression data for Spindle Cell Hemangioma.

Pathways for Spindle Cell Hemangioma

Pathways related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.87 IDH1 IDH2
2
Show member pathways
9.74 IDH1 IDH2

GO Terms for Spindle Cell Hemangioma

Biological processes related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tricarboxylic acid cycle GO:0006099 9.32 IDH1 IDH2
2 2-oxoglutarate metabolic process GO:0006103 9.26 IDH1 IDH2
3 NADP metabolic process GO:0006739 9.16 IDH1 IDH2
4 isocitrate metabolic process GO:0006102 8.96 IDH1 IDH2
5 glyoxylate cycle GO:0006097 8.62 IDH1 IDH2

Molecular functions related to Spindle Cell Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NAD binding GO:0051287 9.26 IDH1 IDH2
2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.16 IDH1 IDH2
3 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH1 IDH2
4 isocitrate dehydrogenase activity GO:0004448 8.62 IDH1 IDH2

Sources for Spindle Cell Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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