MCID: SPN035
MIFTS: 51

Spindle Cell Sarcoma

Categories: Cancer diseases

Aliases & Classifications for Spindle Cell Sarcoma

MalaCards integrated aliases for Spindle Cell Sarcoma:

Name: Spindle Cell Sarcoma 12 6 15
Sarcoma 43 71
Sarcoma, Spindle Cell 71
Sarcoma Spindle Cell 54
Sarcoma - Category 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4235
MeSH 43 D012509
NCIt 49 C27005
SNOMED-CT 67 9801004
UMLS 71 C0205945 C1261473 C1299262

Summaries for Spindle Cell Sarcoma

Disease Ontology : 12 A sarcoma that results in cells that are spindle-shaped. They are usually resistant to radiation therapy.

MalaCards based summary : Spindle Cell Sarcoma, also known as sarcoma, is related to mediastinum sarcoma and ewing sarcoma of bone. An important gene associated with Spindle Cell Sarcoma is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Cytoskeletal Signaling. The drugs Lopinavir and Lamivudine have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and breast.

Wikipedia : 74 Spindle cell sarcoma is a type of connective tissue cancer in which the cells are spindle-shaped when... more...

Related Diseases for Spindle Cell Sarcoma

Diseases related to Spindle Cell Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2174)
# Related Disease Score Top Affiliating Genes
1 mediastinum sarcoma 34.2 MDM2 KRT7
2 ewing sarcoma of bone 34.2 VIM DES
3 endometrial stromal sarcoma 33.9 VIM S100B DES ACTC1
4 alveolar soft part sarcoma 33.9 VIM MYOG DES ACTC1
5 reticulum cell sarcoma 33.9 VIM MUC1 DES ACTC1
6 gallbladder sarcoma 33.8 MYOG DES
7 pancreas sarcoma 33.8 SERPINA3 MDM2
8 extraskeletal ewing sarcoma 33.8 VIM MUC1 DES
9 epithelioid sarcoma 33.7 VIM MUC1 KRT7 CD34
10 esophagus sarcoma 33.6 SSX2 CD34
11 vulvar sarcoma 33.6 CD34 ACTC1
12 undifferentiated embryonal sarcoma of the liver 33.5 SERPINA3 MYOG MDM2
13 central epithelioid sarcoma 33.4 VIM KRT7 CD34
14 vulvar proximal-type epithelioid sarcoma 33.3 VIM KRT7 CD34
15 botryoid rhabdomyosarcoma 33.2 MYOG DES ACTC1
16 retroperitoneal sarcoma 33.0 SSX2 MYOG MDM2 CD34
17 dendritic cell tumor 32.9 VIM S100B NCOA2 MUC1 ACTC1
18 bone angioendothelial sarcoma 32.9 SSX1 SS18
19 meninges sarcoma 32.9 SSX2 SS18 SERPINA3
20 kidney sarcoma 32.8 SSX2 SSX1 SS18
21 uterine carcinosarcoma 32.8 VIM VEGFA MUC1 DES
22 embryonal sarcoma 32.5 VIM SERPINA3 S100B MYOG MDM2 DES
23 desmoplastic small round cell tumor 32.5 VIM MUC1 DES
24 reticulosarcoma 32.4 SERPINA3 MUC1 CDKN1B
25 adenosarcoma 32.1 VIM SERPINA3 DES ACTC1
26 lung sarcoma 32.1 SSX2 SSX1 SS18 CD34
27 rhabdoid cancer 32.1 SSX2 SS18 MYOG
28 bednar tumor 32.1 VIM S100B
29 biphasic synovial sarcoma 32.0 VIM SSX2 SSX1 SS18 MUC1 DES
30 mesothelioma, malignant 31.9 VIM NF2 MUC1 KRT7 DES
31 prostate angiosarcoma 31.8 VEGFA CD34
32 epithelioid cell synovial sarcoma 31.8 SSX2 SSX1 SS18 KRT7 CD34
33 uterus leiomyosarcoma 31.6 MYOG KRT7 CD34
34 breast leiomyosarcoma 31.5 VEGFA KRT7 CD34
35 chordoma 31.3 VIM VEGFA SERPINA3 S100B MUC1 KRT7
36 wilms tumor 1 31.1 VEGFA MYOG KRT7 CD34
37 soft tissue sarcoma 31.0 VEGFA MDM2
38 chondrosarcoma, extraskeletal myxoid 30.9 SSX2 SSX1 SS18 CD34
39 monophasic synovial sarcoma 30.9 VIM SSX2 SSX1 SS18 S100B MUC1
40 rhabdoid tumor predisposition syndrome 1 30.8 VIM MUC1 DES ACTC1
41 rare tumor 30.8 NF2 DES ACTC1
42 meningioma, radiation-induced 30.8 VIM S100B NF2 MUC1
43 malignant mesenchymoma 30.7 SSX2 SERPINA3 MYOG MDM2 DES CD34
44 leiomyoma 30.6 VIM DES CD34 ACTC1
45 benign mesothelioma 30.6 KRT7 CD34
46 dedifferentiated liposarcoma 30.6 MYOG MDM2 DES ACTC1
47 retroperitoneal fibrosis 30.5 VIM MDM2
48 pyogenic granuloma 30.5 CD34 ACTC1
49 secretory meningioma 30.5 VIM SERPINA3 NF2 MUC1 KRT7
50 lymphangiosarcoma 30.4 VEGFA CD34

Graphical network of the top 20 diseases related to Spindle Cell Sarcoma:



Diseases related to Spindle Cell Sarcoma

Symptoms & Phenotypes for Spindle Cell Sarcoma

Drugs & Therapeutics for Spindle Cell Sarcoma

Drugs for Spindle Cell Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 603)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lopinavir Approved Phase 4 192725-17-0 92727