MCID: SPN048
MIFTS: 22

Spindle Cell Thymoma

Categories: Cancer diseases, Immune diseases, Endocrine diseases

Aliases & Classifications for Spindle Cell Thymoma

MalaCards integrated aliases for Spindle Cell Thymoma:

Name: Spindle Cell Thymoma 12 15
Thymoma, Medullary 12
Medullary Thymoma 12
Thymoma, Type a 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3279
NCIt 50 C6454
SNOMED-CT 68 128707003
UMLS 73 C1266091

Summaries for Spindle Cell Thymoma

MalaCards based summary : Spindle Cell Thymoma, also known as thymoma, medullary, is related to thymoma and malignant type a thymoma. An important gene associated with Spindle Cell Thymoma is DES (Desmin). Related phenotypes are Decreased HPV16-GFP infection and Reduced mammosphere formation

Related Diseases for Spindle Cell Thymoma

Diseases related to Spindle Cell Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 thymoma 29.0 CD5 LCK
2 malignant type a thymoma 11.1
3 cutaneous leiomyosarcoma 10.4 DES MUC1
4 parachordoma 10.4 DES MUC1
5 ossifying fibromyxoid tumor 10.4 DES MUC1
6 syringocystadenoma papilliferum 10.4 DES MUC1
7 spindle cell rhabdomyosarcoma 10.4 DES MUC1
8 biphasic synovial sarcoma 10.4 DES MUC1
9 ovarian small cell carcinoma 10.4 DES MUC1
10 syringoma 10.4 DES MUC1
11 pleomorphic liposarcoma 10.4 DES MUC1
12 ischemic fasciitis 10.4 DES MUC1
13 desmoplastic small round cell tumor 10.3 DES MUC1
14 proximal spinal muscular atrophy 10.3 DES MUC1
15 perivascular epithelioid cell tumor 10.3 DES MUC1
16 reticulum cell sarcoma 10.3 DES MUC1
17 dedifferentiated liposarcoma 10.3 DES MUC1
18 mesenchymal chondrosarcoma 10.3 DES MUC1
19 extraskeletal ewing sarcoma 10.3 DES MUC1
20 plasmablastic lymphoma 10.3 DES MUC1
21 spindle cell sarcoma 10.3 DES MUC1
22 endosalpingiosis 10.3 MUC1 PAX8
23 rhabdoid cancer 10.3 DES MUC1
24 hemangiopericytoma, malignant 10.2 DES MUC1
25 sarcomatoid renal cell carcinoma 10.2 MUC1 PAX8
26 nephrogenic adenoma 10.2 MUC1 PAX8
27 malignant fibroxanthoma 10.2 DES MUC1
28 fasciitis 10.2 DES MUC1
29 spindle cell carcinoma 10.2 DES MUC1
30 mixed type thymoma 10.2 CD5 PAX8
31 atypical teratoid rhabdoid tumor 10.1 DES MUC1
32 giant cell tumor 10.1 DES MUC1
33 malignant ovarian surface epithelial-stromal neoplasm 10.0 MUC1 PAX8
34 ovary epithelial cancer 10.0 MUC1 PAX8
35 sarcoma, synovial 10.0 DES MUC1
36 chordoma 9.9 DES MUC1
37 thymus cancer 9.9 CD5 MUC1
38 pemphigus vulgaris, familial 9.8
39 factor x deficiency 9.8
40 pemphigus vulgaris 9.8
41 melanoma 9.8
42 cervicitis 9.8
43 pemphigus 9.8
44 carcinoid syndrome 9.8
45 cd45 deficiency 9.7 CD5 LCK
46 papillary carcinoma 9.7 MUC1 PAX8
47 dendritic cell thymoma 9.1 CD5 CD58 LCK
48 epithelial malignant thymoma 9.1 CD5 CD58 LCK

Graphical network of the top 20 diseases related to Spindle Cell Thymoma:



Diseases related to Spindle Cell Thymoma

Symptoms & Phenotypes for Spindle Cell Thymoma

GenomeRNAi Phenotypes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased HPV16-GFP infection GR00350-A 9.13 DES LCK PAX8
2 Reduced mammosphere formation GR00396-S 8.92 CD5 DES LCK PAX8

Drugs & Therapeutics for Spindle Cell Thymoma

Search Clinical Trials , NIH Clinical Center for Spindle Cell Thymoma

Genetic Tests for Spindle Cell Thymoma

Anatomical Context for Spindle Cell Thymoma

Publications for Spindle Cell Thymoma

Articles related to Spindle Cell Thymoma:

(show all 12)
# Title Authors Year
1
Concurrent spindle-cell thymoma and thymic cysts in a Barbary sheep (Ammotragus lervia): case report and review of the literature. ( 27698165 )
2016
2
The histomorphologic spectrum of spindle cell thymoma. ( 23260329 )
2012
3
Malignant melanoma of mediastinum misdiagnosed as a spindle cell thymoma in a fine needle aspirate: a case report. ( 16124173 )
2005
4
Fine-needle aspiration biopsy of ectopic cervical spindle-cell thymoma: a case report. ( 15880711 )
2005
5
Images in clinical medicine. Spindle-cell thymoma. ( 14534337 )
2003
6
Primary intrapulmonary spindle cell thymoma with marked granulomatous reaction: report of a case with review of literature. ( 14615837 )
2003
7
Pericardial rhabdomyomatous spindle cell thymoma with mucinous cystic degeneration. ( 11422489 )
2001
8
Pemphigus vulgaris associated with spindle cell thymoma. ( 8080421 )
1993
9
Thymic carcinosarcoma associated with a spindle cell thymoma: an immunohistochemical study. ( 1398523 )
1992
10
Novel factor X deficiency. Normal partial thromboplastin time and associated spindle cell thymoma. ( 4014297 )
1985
11
A spindle cell varient of thymic carcinoid tumor. A clinical, histologic, and fine structural study with emphasis on its distinction from spindle cell thymoma. ( 946757 )
1976
12
Epithelial nature of spindle-cell thymoma. An ultrastructural study. ( 5051674 )
1972

Variations for Spindle Cell Thymoma

Expression for Spindle Cell Thymoma

Search GEO for disease gene expression data for Spindle Cell Thymoma.

Pathways for Spindle Cell Thymoma

GO Terms for Spindle Cell Thymoma

Biological processes related to Spindle Cell Thymoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 T cell costimulation GO:0031295 8.62 CD5 LCK

Sources for Spindle Cell Thymoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....