Aliases & Classifications for Splenic Abscess

MalaCards integrated aliases for Splenic Abscess:

Name: Splenic Abscess 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:2530
NCIt 50 C35347
SNOMED-CT 67 82053000
ICD10 32 D73.3
UMLS 70 C0272412

Summaries for Splenic Abscess

MalaCards based summary : Splenic Abscess is related to peritonitis and endocarditis, and has symptoms including hepatosplenomegaly An important gene associated with Splenic Abscess is LACTB (Lactamase Beta), and among its related pathways/superpathways is RHO GTPases Activate NADPH Oxidases. Affiliated tissues include spleen, colon and liver, and related phenotype is homeostasis/metabolism.

Related Diseases for Splenic Abscess

Diseases related to Splenic Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 544)
# Related Disease Score Top Affiliating Genes
1 peritonitis 31.0 F2 CRP ALB
2 endocarditis 31.0 LACTB F2 CRP ALB
3 cat-scratch disease 30.6 CRP CD4
4 typhoid fever 30.5 GPT F2 CRP ALB
5 splenic infarction 30.4 GPT F2 CRP ALB
6 aortic valve insufficiency 30.3 F2 CRP ALB
7 acquired immunodeficiency syndrome 30.3 CRP CD4 ALB
8 mitral valve insufficiency 30.2 F2 CRP ALB
9 acute pyelonephritis 30.1 GPT CRP ALB
10 pleural empyema 30.1 GPT F2 CRP CD4 ALB
11 actinomycosis 30.1 CRP CD4 ALB
12 aortitis 30.0 CRP CD4
13 bartonellosis 30.0 CRP CD4
14 splenic sequestration 30.0 F2 CD4
15 salmonellosis 30.0 LACTB GPT CD4 ALB
16 iritis 30.0 CRP CD4
17 liver cirrhosis 30.0 GPT F2 CRP ALB
18 chlamydia pneumonia 30.0 CRP CD4
19 splenic tuberculosis 30.0 F2 CRP CD4 ALB
20 cholecystitis 29.9 GPT F2 ALB
21 hepatorenal syndrome 29.9 GPT F2 ALB
22 neutrophilic dermatosis, acute febrile 29.9 CSF3 CRP
23 metabolic acidosis 29.9 GPT F2 ALB
24 meningoencephalitis 29.8 CRP CD4 ALB
25 peptic ulcer perforation 29.8 CRP ATP12A ALB
26 clostridium difficile colitis 29.8 CRP ATP12A ALB
27 gastroenteritis 29.8 LACTB CSF3 CRP ALB
28 disease by infectious agent 29.8 LACTB GPT CRP CD4 ALB
29 intestinal obstruction 29.7 GPT CRP ATP12A ALB
30 pyelonephritis 29.7 GPT CSF3 CRP ALB
31 thrombocytosis 29.7 F2 CSF3 CRP ALB
32 bronchopneumonia 29.6 GPT CRP CD4 ALB
33 appendicitis 29.5 CSF3 CRP ALB
34 portal hypertension 29.5 GPT F2 CD4 ALB
35 respiratory failure 29.5 GPT F2 CRP CD4 ALB
36 esophageal varix 29.5 GPT F2 ATP12A ALB
37 bacterial infectious disease 29.5 CSF3 CRP CD4
38 sickle cell anemia 29.4 GPT F2 CSF3 CRP ALB
39 pneumonia 29.4 LACTB CSF3 CRP ALB
40 pancytopenia 29.4 CSF3 CRP CD4
41 splenic disease 29.3 GPT F2 CRP CD4 ALB
42 acute cystitis 29.3 GPT F2 CRP CD4 ALB
43 miliary tuberculosis 29.2 CSF3 CRP CD4 ALB
44 drug allergy 29.1 GPT CRP CD4 ATP12A ALB
45 dysentery 29.1 GPT CRP CD4 ATP12A ALB
46 thrombocytopenia 29.0 GPT F2 CSF3 CRP ALB
47 malaria 28.4 GPT F2 CYBB CSF3 CRP CD4
48 cellulitis 28.4 LACTB GPT F2 CSF3 CRP CD4
49 exanthem 28.2 GPT F2 CSF3 CRP CD4 ATP12A
50 deficiency anemia 28.2 GPT F2 CSF3 CRP CD4 ATP12A

Graphical network of the top 20 diseases related to Splenic Abscess:



Diseases related to Splenic Abscess

Symptoms & Phenotypes for Splenic Abscess

UMLS symptoms related to Splenic Abscess:


hepatosplenomegaly

MGI Mouse Phenotypes related to Splenic Abscess:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 ALB ATP12A CD4 CRP CYBB F2

Drugs & Therapeutics for Splenic Abscess

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Sarcopaenia is a Useful Risk Stratification Tool for Surgeons to Prognosticate Splenic Abscess Patients- A Retrospective Case Control Study Completed NCT03967041

Search NIH Clinical Center for Splenic Abscess

Genetic Tests for Splenic Abscess

Anatomical Context for Splenic Abscess

MalaCards organs/tissues related to Splenic Abscess:

40
Spleen, Colon, Liver, Myeloid, Bone, Bone Marrow, Kidney

Publications for Splenic Abscess

Articles related to Splenic Abscess:

(show top 50) (show all 937)
# Title Authors PMID Year
1
Splenic Abscess Following Sleeve Gastrectomy: A Systematic Review of Clinical Presentation and Management Methods. 61
33791929 2021
2
Splenic abscess by Cutibacterium propionicum in poorly controlled type 2 diabetes. 61
33795281 2021
3
Splenic Abscess Complicating Bariatric Surgery : A Systematic Review. 61
33703937 2021
4
Splenic Abscess Caused by Salmonella Typhi: an Uncommon Presentation. 61
32863358 2021
5
Sarcopenia is a useful risk stratification tool to prognosticate splenic abscess patients in the emergency department. 61
32917483 2021
6
Disseminated Melioidosis with Spinal Intraosseous Abscess. 61
33742639 2021
7
Hemophagocytic Lymphohistiocytosis in Children with Chronic Granulomatous Disease-Single-Center Experience from North India. 61
33259975 2021
8
Septic shock due to Granulicatella adiacens after endoscopic ultrasound-guided biopsy of a splenic mass: A case report. 61
33716452 2021
9
[Gas-Producing Splenic Abscess after Spleen Metastasis of Left Renal Cell Carcinoma Spleen Metastasis Successfully Treated with Sunitinib]. 61
33657773 2021
10
Isolated splenic abscess due to melioidosis in type 1 diabetes mellitus: laboratory diagnosis of Burkholderia pseudomallei in resource-restricted setting. 61
33541991 2021
11
Non-traumatic rupture of voluminous non-typhoid Salmonella splenic abscess presenting with peritonitis: Case report and review of the literature. 61
33477075 2021
12
Splenic abscess diagnosed following relapsing sterile peritonitis in a peritoneal dialysis patient: A case report with literature review. 61
33609413 2021
13
Primary splenic hodgkin lymphoma masquerading as splenic abscess. 61
33510123 2021
14
Clinical, Immunological, and Molecular Profile of Chronic Granulomatous Disease: A Multi-Centric Study of 236 Patients From India. 61
33717137 2021
15
An unusual case of abdominal pain and splenomegaly in a paediatric patient. 61
33796309 2021
16
Endovascular management of giant visceral artery aneurysms. 61
33436829 2021
17
A non-resolving splenic 'abscess' in an elderly male - An unusual manifestation of splenic lymphoma. 61
33356940 2020
18
Secondary infection of amoeba and typhoid fever in severe malnourished pediatric patient with Type I choledocal cyst: a case report. 61
33391767 2020
19
Splenic abscess in a tertiary care centre in India: clinical characteristics and prognostic factors. 61
33369845 2020
20
Pathogenic potential of Parabacteroides distasonis revealed in a splenic abscess case: a truth unfolded. 61
33318274 2020
21
A Clinical Challenge in the Emergency Department: A Case of Klebsiella Infective Endocarditis Presenting With Splenic Abscess. 61
33101821 2020
22
Surgical infective endocarditis and concurrent splenic abscess requiring splenectomy: a case series and review of the literature. 61
32535414 2020
23
Streptococcus agalactiae-Related Splenic Abscess in Uncontrolled Diabetes Mellitus. 61
32884869 2020
24
Large Splenic Abscess Caused by Non-Typhoidal Salmonella in a Healthy Child Treated with Percutaneous Drainage. 61
32756354 2020
25
Splenic abscess after arterial embolization: a rare cause of acute abdomen. 61
32582433 2020
26
Systemic Melioidosis With Ruptured Splenic Abscess. 61
32509481 2020
27
Isolated splenic abscess due to Salmonella Berta in a healthy adult. 61
32269050 2020
28
Successful surgical management of coarctation of the aorta with infective endaortitis and splenic abscess: a case report. 61
32270732 2020
29
Splenic Abscess: Characterizing Management and Outcomes for a Rare Disease. 61
32223819 2020
30
Bilateral End-Organ Endophthalmitis in Setting of Serratia marcescens Urosepsis on 18F-FDG PET/CT. 61
31876818 2020
31
Challenges in the management of life-threatening complications caused by a rare case of sarcoid-lymphoma syndrome. 61
31832766 2020
32
Tuberculous splenic abscess in the immunocompetent host: a report and review of literature. 61
32072799 2020
33
Large-volume pneumoperitoneum and septic peritonitis secondary to splenic abscess rupture in a dog. 61
32020930 2020
34
Splenic abscess as a rare presentation of blastomycosis. 61
32060116 2020
35
Management of leak after sleeve gastrectomy: outcomes of 73 cases, treatment algorithm and predictors of resolution. 61
31707571 2020
36
Splenic mass of uncertain etiology in a 15-year-old male patient: a case report. 61
31988776 2020
37
Laparoscopic near-total splenectomy. Report of a case. 61
33191191 2020
38
A case report of septic shock and splenic abscess formation secondary to gastric band erosion: A rare complication of laparoscopic adjustable gastric banding. 61
32276217 2020
39
Splenic Abscess after Sleeve Gastrectomy. 61
32328107 2020
40
Colonic Adenocarcinoma Presenting as Splenic Abscess Secondary to Suspected Microperforation. 61
33283530 2020
41
Tuberculosis and Melioidosis at Distinct Sites Occurring Simultaneously. 61
31984142 2020
42
Lactobacillus acidophilus-Induced Endocarditis and Associated Splenic Abscess. 61
32313707 2020
43
Splenic abscess complicated by pleural empyema: A rare case report from rural Nepal. 61
33076203 2020
44
Severe Complications After Splenic Artery Embolization for Portal Hypertension Due to Hepatic Cirrhosis. 61
32110126 2020
45
Splenic abscess caused by Streptococcus anginosus bacteremia secondary to urinary tract infection: a case report and literature review. 61
33336055 2020
46
[A Case of Chemotherapy with Abscess Drainage for Pancreatic Cancer Detected Due to Peritonitis]. 61
32156964 2019
47
Hydatid Cyst of Spleen Presenting with Vague Symptoms: A Diagnostic Conundrum. 61
31737457 2019
48
Pylephlebitis treated with apixaban. 61
31545676 2019
49
Endovascular embolization of arterial bleeding in patients with severe acute pancreatitis. 61
31534570 2019
50
Gangrenous gas necrosis of the spleen: a case report. 61
31488072 2019

Variations for Splenic Abscess

Expression for Splenic Abscess

Search GEO for disease gene expression data for Splenic Abscess.

Pathways for Splenic Abscess

Pathways related to Splenic Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.74 NCF2 CYBB

GO Terms for Splenic Abscess

Cellular components related to Splenic Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADPH oxidase complex GO:0043020 8.62 NCF2 CYBB

Biological processes related to Splenic Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 superoxide metabolic process GO:0006801 9.16 NCF2 CYBB
2 superoxide anion generation GO:0042554 8.96 NCF2 CYBB
3 respiratory burst GO:0045730 8.62 NCF2 CYBB

Molecular functions related to Splenic Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 superoxide-generating NADPH oxidase activity GO:0016175 8.62 NCF2 CYBB

Sources for Splenic Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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